Page last updated: 2024-11-02

benoxinate and Intraocular Pressure

benoxinate has been researched along with Intraocular Pressure in 10 studies

benoxinate: RN given refers to parent cpd; structure
oxybuprocaine : A benzoate ester in which 4-amino-3-butoxybenzoic acid and 2-(diethylamino)ethanol have combined to form the ester bond; an ester-based local anaesthetic (ester "caine") used especially in ophthalmology and otolaryngology.

Intraocular Pressure: The pressure of the fluids in the eye.

Research Excerpts

ExcerptRelevanceReference
" A prospective study on 18 volunteers and 10 glaucoma patients was set up to find out whether oxybuprocaine eyedrops or repeated applanation tonometry could have anything to do with this."7.67The influence of oxybuprocaine (Novesine) on the intraocular pressure. ( de Heer, LJ; Leys, M; van Rij, G, 1986)
"We studied, using anesthetized albino rabbits, whether polymodal receptors are responsible for rise in the intraocular pressure (IOP) caused by algesic substances, and also whether substance P (SP) is involved in this phenomenon."3.68Implication of polymodal receptor activities in intraocular pressure elevation by neurogenic inflammation. ( Awaya, S; Kumazawa, T; Mizumura, K; Yokoyama, K, 1990)
" A prospective study on 18 volunteers and 10 glaucoma patients was set up to find out whether oxybuprocaine eyedrops or repeated applanation tonometry could have anything to do with this."3.67The influence of oxybuprocaine (Novesine) on the intraocular pressure. ( de Heer, LJ; Leys, M; van Rij, G, 1986)
"In aging eyes phenylephrine drops have no significant effect on the depth of the anterior chamber, whereas pilocarpine drops produce a significant shallowing."3.66Acute shallowing of the anterior chamber. ( Mapstone, R, 1981)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19904 (40.00)18.7374
1990's1 (10.00)18.2507
2000's3 (30.00)29.6817
2010's2 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ehongo, A1
De Maertelaer, V1
Pourjavan, S1
Sanchis-Gimeno, JA1
Palanca-Sanfrancisco, JM1
García-Lázaro, S1
Madrid-Costa, D1
Cerviño, A1
Jóhannesson, G1
Hallberg, P1
Eklund, A1
Behndig, A1
Lindén, C1
Sauder, G1
Jonas, JB1
Innemee, HC1
de Jonge, A1
van Meel, JC1
Timmermans, PB1
van Zwieten, PA1
Mapstone, R1
Jose, JG1
Basta, M1
Cramer, KJ1
Fain, M1
Turetsky, D1
Pianka, P1
Weintraub-Padova, H1
Lazar, M1
Geyer, O1
Yokoyama, K1
Awaya, S1
Mizumura, K1
Kumazawa, T1
Leys, M1
van Rij, G1
de Heer, LJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of Clonidine Added to Lidocaine in Sub-Tenon's and Peribulbar Anesthesia: Assessments of Intraocular Pressure (IOP), Ocular Perfusion Pressure (OPP) and Ocular Pulse Amplitude (OPA)[NCT02733757]Phase 280 participants (Actual)Interventional2013-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Intraocular Pressure (IOP)

(NCT02733757)
Timeframe: Within 10 minutes before the surgery procedure

InterventionmmHg (Mean)
Sub-Tenon's Group Control18
Sub-Tenon's Group Clonidine16
Peribulbar Group Control19
Peribulbar Group Clonidine16

Trials

2 trials available for benoxinate and Intraocular Pressure

ArticleYear
Topical anesthesia for penetrating trabeculectomy.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2002, Volume: 240, Issue:9

    Topics: Aged; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Local; Cocaine; Female; Glaucoma; Human

2002
Effect of sub-Tenon's and peribulbar anesthesia on intraocular pressure and ocular pulse amplitude.
    Journal of cataract and refractive surgery, 2001, Volume: 27, Issue:8

    Topics: Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Blood Pressure; Fascia; Female; Huma

2001

Other Studies

8 other studies available for benoxinate and Intraocular Pressure

ArticleYear
Effect of topical corneal anaesthesia on ocular response analyzer parameters: pilot study.
    International ophthalmology, 2009, Volume: 29, Issue:5

    Topics: Adult; Anesthetics, Local; Cornea; Cross-Sectional Studies; Humans; Intraocular Pressure; Middle Age

2009
The effect of anesthetic eye drop instillation on the distribution of corneal thickness.
    Cornea, 2013, Volume: 32, Issue:5

    Topics: Administration, Topical; Anesthetics, Local; Cornea; Corneal Topography; Emmetropia; Female; Humans;

2013
Effects of topical anaesthetics and repeated tonometry on intraocular pressure.
    Acta ophthalmologica, 2014, Volume: 92, Issue:2

    Topics: Adult; Anesthetics, Local; Female; Healthy Volunteers; Humans; Intraocular Pressure; Male; Middle Ag

2014
Differential effects of selective alpha 1- and alpha 2-adrenoceptor agonists on intraocular pressure in the conscious rabbit.
    Documenta ophthalmologica. Advances in ophthalmology, 1982, Jan-29, Volume: 52, Issue:3-4

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Clonidine; Female; Intra

1982
Acute shallowing of the anterior chamber.
    The British journal of ophthalmology, 1981, Volume: 65, Issue:7

    Topics: Acetazolamide; Aged; Aging; Anterior Chamber; Glaucoma; Humans; Intraocular Pressure; Iris; Middle A

1981
Lack of effects of anesthetic on measurement of intraocular pressure by Goldmann tonometry.
    American journal of optometry and physiological optics, 1983, Volume: 60, Issue:4

    Topics: Administration, Topical; Anesthetics, Local; Humans; Intraocular Pressure; Procaine; Propoxycaine; T

1983
Implication of polymodal receptor activities in intraocular pressure elevation by neurogenic inflammation.
    Japanese journal of ophthalmology, 1990, Volume: 34, Issue:2

    Topics: Animals; Anterior Chamber; Aspirin; Bradykinin; Female; Glucose; Intraocular Pressure; Male; Neuriti

1990
The influence of oxybuprocaine (Novesine) on the intraocular pressure.
    Documenta ophthalmologica. Advances in ophthalmology, 1986, Jan-15, Volume: 61, Issue:3-4

    Topics: Adult; Female; Glaucoma; Humans; Intraocular Pressure; Male; Procaine; Tonometry, Ocular

1986