bengazole-a has been researched along with Melanoma* in 1 studies
1 other study(ies) available for bengazole-a and Melanoma
Article | Year |
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New structures and bioactivity patterns of bengazole alkaloids from a choristid marine sponge.
New bengazoles 3-9 as inseparable mixtures are reported from the sponge Jaspis cf. coricea collected in Papua New Guinea. These compounds contain a new variation of the unusual bisoxazole core present in bengazole A [1]. The B-ring oxazole hexatetraol side chain is varyingly substituted with either myristic acid or 13-methylmyristic acid. Hydrolysis of three different bengazole mixtures each yielded an identical tetraol, bengazole Z [11]. Topics: Alkaloids; Animals; Antineoplastic Agents; Colonic Neoplasms; Drug Screening Assays, Antitumor; Humans; Hydrolysis; Melanoma; Oxazoles; Porifera; Tumor Cells, Cultured | 1993 |