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benfluorex and Pulmonary Hypertension

benfluorex has been researched along with Pulmonary Hypertension in 10 studies

Research Excerpts

ExcerptRelevanceReference
"Benfluorex is a fenfluramine derivative which has been marketed between 1976 and 2009."5.46Fatal postoperative systemic pulmonary hypertension in benfluorex-induced valvular heart disease surgery: A case report. ( Banfi, C; Baufreton, C; Bruneval, P; Ennezat, PV; Fouquet, O; Giraud, R; Rousselet, MC, 2017)
"Benfluorex was marketed in France until 2009, despite its similar pharmacological properties with fenfluramine and its derivatives known to be a cause of pulmonary arterial hypertension (PAH)."5.38Pulmonary hypertension associated with benfluorex exposure. ( Bergot, E; Bourdin, A; Chaumais, MC; Cottin, V; Dromer, C; Frachon, I; Habib, G; Humbert, M; Jaïs, X; Lamblin, N; Montani, D; Pison, C; Poubeau, P; Prevot, G; Reynaud-Gaubert, M; Sanchez, O; Savale, L; Simonneau, G; Sitbon, O; Tubert-Bitter, P, 2012)
" Further studies should be conducted to determine the subsequent course of benfluorex-induced VHD and PAH, and to identify genetic, biological and clinical factors that determine individual susceptibility to developing such adverse effects."2.50Adverse effects of benfluorex on heart valves and pulmonary circulation. ( Andréjak, M; Maréchaux, S; Peltier, M; Szymanski, C; Tribouilloy, C, 2014)
"Benfluorex is a fenfluramine derivative which has been marketed between 1976 and 2009."1.46Fatal postoperative systemic pulmonary hypertension in benfluorex-induced valvular heart disease surgery: A case report. ( Banfi, C; Baufreton, C; Bruneval, P; Ennezat, PV; Fouquet, O; Giraud, R; Rousselet, MC, 2017)
"Benfluorex was marketed in France until 2009, despite its similar pharmacological properties with fenfluramine and its derivatives known to be a cause of pulmonary arterial hypertension (PAH)."1.38Pulmonary hypertension associated with benfluorex exposure. ( Bergot, E; Bourdin, A; Chaumais, MC; Cottin, V; Dromer, C; Frachon, I; Habib, G; Humbert, M; Jaïs, X; Lamblin, N; Montani, D; Pison, C; Poubeau, P; Prevot, G; Reynaud-Gaubert, M; Sanchez, O; Savale, L; Simonneau, G; Sitbon, O; Tubert-Bitter, P, 2012)
"Benfluorex is an amphetamine appetite suppressant derived from fenfluramine."1.36Benfluorex: increasing reports of valve disorders. ( , 2010)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (10.00)29.6817
2010's9 (90.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Szymanski, C1
Andréjak, M1
Peltier, M1
Maréchaux, S2
Tribouilloy, C2
Baufreton, C1
Bruneval, P1
Rousselet, MC1
Ennezat, PV1
Fouquet, O1
Giraud, R1
Banfi, C1
Gueffet, JP2
Piriou, N1
Trochu, JN1
Droogmans, S1
Cosyns, B1
Van Camp, G1
Le Ven, F1
Habib, G2
Eicher, JC1
Blanchard-Lemoine, B1
Rousseau, J1
Hénon, P1
Jobic, Y1
Etienne, Y1
Nau, JY1
Savale, L1
Chaumais, MC1
Cottin, V1
Bergot, E1
Frachon, I1
Prevot, G1
Pison, C1
Dromer, C1
Poubeau, P1
Lamblin, N1
Reynaud-Gaubert, M1
Bourdin, A1
Sanchez, O1
Tubert-Bitter, P1
Jaïs, X1
Montani, D1
Sitbon, O1
Simonneau, G1
Humbert, M1

Reviews

1 review available for benfluorex and Pulmonary Hypertension

ArticleYear
Adverse effects of benfluorex on heart valves and pulmonary circulation.
    Pharmacoepidemiology and drug safety, 2014, Volume: 23, Issue:7

    Topics: Echocardiography; Fenfluramine; Heart Valve Diseases; Heart Valves; Humans; Hypertension, Pulmonary;

2014

Other Studies

9 other studies available for benfluorex and Pulmonary Hypertension

ArticleYear
Fatal postoperative systemic pulmonary hypertension in benfluorex-induced valvular heart disease surgery: A case report.
    Medicine, 2017, Volume: 96, Issue:2

    Topics: Appetite Depressants; Fatal Outcome; Female; Fenfluramine; Heart Valve Diseases; Heart Valve Prosthe

2017
Benfluorex: negative data in France, but still on the market. Neuropsychiatric disorders, pulmonary hypertension and heart valve damage.
    Prescrire international, 2009, Volume: 18, Issue:101

    Topics: Appetite Depressants; Fenfluramine; France; Heart Valve Diseases; Humans; Hypertension, Pulmonary; N

2009
Benfluorex: increasing reports of valve disorders.
    Prescrire international, 2010, Volume: 19, Issue:105

    Topics: Appetite Depressants; Fenfluramine; France; Heart Valve Diseases; Humans; Hypertension, Pulmonary; P

2010
Valvular heart disease associated with benfluorex.
    Archives of cardiovascular diseases, 2010, Volume: 103, Issue:5

    Topics: Appetite Depressants; Diuretics; Echocardiography, Doppler, Color; Female; Fenfluramine; Furosemide;

2010
Benfluorex: the last chapter of drug-induced valvular heart disease?
    European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology, 2011, Volume: 12, Issue:4

    Topics: Anti-Arrhythmia Agents; Antihypertensive Agents; Appetite Depressants; Europe; Fenfluramine; France;

2011
Valvular heart disease associated with benfluorex therapy: results from the French multicentre registry.
    European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology, 2011, Volume: 12, Issue:4

    Topics: Appetite Depressants; Body Mass Index; Comorbidity; Dose-Response Relationship, Drug; Echocardiograp

2011
Benfluorex: how many deaths?
    Prescrire international, 2011, Volume: 20, Issue:113

    Topics: Appetite Depressants; Familial Primary Pulmonary Hypertension; Fenfluramine; France; Heart Valve Dis

2011
[The French are wary of their drugs].
    Revue medicale suisse, 2011, May-25, Volume: 7, Issue:296

    Topics: Appetite Depressants; Body Mass Index; Cause of Death; Drugs, Generic; Fenfluramine; France; Heart V

2011
Pulmonary hypertension associated with benfluorex exposure.
    The European respiratory journal, 2012, Volume: 40, Issue:5

    Topics: Adult; Aged; Appetite Depressants; Familial Primary Pulmonary Hypertension; Female; Fenfluramine; Hu

2012