benfluorex has been researched along with Mitral Valve Insufficiency in 15 studies
Mitral Valve Insufficiency: Backflow of blood from the LEFT VENTRICLE into the LEFT ATRIUM due to imperfect closure of the MITRAL VALVE. This can lead to mitral valve regurgitation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The authors describe the case of a simultaneous mitral bioprosthesis hypertrophic scaring and native aortic valve fibrosis during benfluorex therapy in a 40-year-old woman." | 7.78 | Mitral bioprosthesis hypertrophic scaring and native aortic valve fibrosis during benfluorex therapy. ( Ayme-Dietrich, E; Bischoff, N; Dallemand, R; Gasser, B; Lawson, R; Monassier, L, 2012) |
| "Benfluorex was withdrawn from European markets in June 2010 after reports of an association with heart valve lesions." | 5.38 | Increased risk of left heart valve regurgitation associated with benfluorex use in patients with diabetes mellitus: a multicenter study. ( Arnalsteen, E; Boulanger, J; Donal, E; Ederhy, S; Ennezat, PV; Garban, T; Jeu, A; Jobic, Y; Maréchaux, S; Réant, P; Rusinaru, D; Tribouilloy, C, 2012) |
| "Adjusted RR for mitral insufficiency and aortic insufficiency admissions were 2." | 5.36 | Benfluorex and valvular heart disease: a cohort study of a million people with diabetes mellitus. ( Allemand, H; Fagot, JP; Montastruc, JL; Neumann, A; Païta, M; Ricordeau, P; Simon, D; Tuppin, P; Weill, A, 2010) |
| "The authors describe the case of a simultaneous mitral bioprosthesis hypertrophic scaring and native aortic valve fibrosis during benfluorex therapy in a 40-year-old woman." | 3.78 | Mitral bioprosthesis hypertrophic scaring and native aortic valve fibrosis during benfluorex therapy. ( Ayme-Dietrich, E; Bischoff, N; Dallemand, R; Gasser, B; Lawson, R; Monassier, L, 2012) |
| "Benfluorex was withdrawn from European markets in June 2010 after reports of an association with heart valve lesions." | 1.38 | Increased risk of left heart valve regurgitation associated with benfluorex use in patients with diabetes mellitus: a multicenter study. ( Arnalsteen, E; Boulanger, J; Donal, E; Ederhy, S; Ennezat, PV; Garban, T; Jeu, A; Jobic, Y; Maréchaux, S; Réant, P; Rusinaru, D; Tribouilloy, C, 2012) |
| "Adjusted RR for mitral insufficiency and aortic insufficiency admissions were 2." | 1.36 | Benfluorex and valvular heart disease: a cohort study of a million people with diabetes mellitus. ( Allemand, H; Fagot, JP; Montastruc, JL; Neumann, A; Païta, M; Ricordeau, P; Simon, D; Tuppin, P; Weill, A, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 14 (93.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Eugène, M | 1 |
| Bruneval, P | 4 |
| Bonnet, N | 1 |
| Attias, D | 1 |
| Nicot, P | 1 |
| Frachon, I | 2 |
| Hill, C | 1 |
| Tribouilloy, C | 5 |
| Maréchaux, S | 3 |
| Jobic, Y | 5 |
| Jeu, A | 3 |
| Ederhy, S | 2 |
| Donal, E | 2 |
| Réant, P | 2 |
| Arnalsteen, E | 2 |
| Boulanger, J | 2 |
| Garban, T | 2 |
| Ennezat, PV | 4 |
| Andréjak, M | 4 |
| Rusinaru, D | 5 |
| Borer, JS | 1 |
| Plurien, F | 1 |
| Iung, B | 1 |
| Malergue, MC | 1 |
| Czitrom, D | 1 |
| Henon, P | 1 |
| Tribouilloy, L | 1 |
| Leleu, F | 1 |
| Sevestre, H | 1 |
| Peltier, M | 1 |
| Caus, T | 1 |
| Etienne, Y | 1 |
| Le Gal, G | 1 |
| Humbert, M | 1 |
| Leroyer, C | 1 |
| Weill, A | 1 |
| Païta, M | 1 |
| Tuppin, P | 1 |
| Fagot, JP | 1 |
| Neumann, A | 1 |
| Simon, D | 1 |
| Ricordeau, P | 1 |
| Montastruc, JL | 2 |
| Allemand, H | 1 |
| Ayme-Dietrich, E | 1 |
| Lawson, R | 1 |
| Gasser, B | 1 |
| Dallemand, R | 1 |
| Bischoff, N | 1 |
| Monassier, L | 1 |
| Noize, P | 1 |
| Sauer, M | 1 |
| Moreau, M | 1 |
| Pathak, A | 1 |
| Bagheri, H | 1 |
2 reviews available for benfluorex and Mitral Valve Insufficiency
| Article | Year |
|---|---|
[About the settlement of litigations concerning the harm caused by benfluorex (Mediator®)].
Topics: Aortic Valve Insufficiency; Appetite Depressants; Causality; Compensation and Redress; Cross-Section | 2013 |
[Benfluorex and valvular heart disease].
Topics: Aortic Valve Insufficiency; Appetite Depressants; Cohort Studies; Cross-Sectional Studies; Echocardi | 2011 |
13 other studies available for benfluorex and Mitral Valve Insufficiency
| Article | Year |
|---|---|
Benfluorex-induced severe primary tricuspid and mitral regurgitation requiring a double-valve replacement.
Topics: Fenfluramine; Heart Valve Prosthesis Implantation; Humans; Hypolipidemic Agents; Mitral Valve Insuff | 2018 |
Frequency of drug-induced valvular heart disease in patients previously exposd to benfluorex: a multicentre prospective study.
Topics: Analysis of Variance; Aortic Valve Insufficiency; Appetite Depressants; Case-Control Studies; Diabet | 2013 |
Drug-induced valve disease and considerations of benefit versus risk.
Topics: Aortic Valve Insufficiency; Appetite Depressants; Female; Fenfluramine; Humans; Hypolipidemic Agents | 2013 |
Calcifications in benfluorex-induced valve heart disease: a misknown association.
Topics: Aged; Aortic Valve Insufficiency; Appetite Depressants; Calcinosis; Fenfluramine; Heart Valve Diseas | 2015 |
Fatal dynamic mitral regurgitation as a presentation of benfluorex-Induced valvular heart toxicity.
Topics: Aged; Appetite Depressants; Autopsy; Echocardiography; Fatal Outcome; Fenfluramine; Heart Valve Pros | 2015 |
Restrictive organic mitral regurgitation associated with benfluorex therapy.
Topics: Aged; Appetite Depressants; Body Mass Index; Cardiomyopathy, Restrictive; Diabetes Mellitus; Drug Th | 2010 |
Benfluorex and unexplained valvular heart disease: a case-control study.
Topics: Aged; Case-Control Studies; Female; Fenfluramine; Heart Valve Diseases; Humans; Hypolipidemic Agents | 2010 |
Benfluorex and valvular heart disease: a cohort study of a million people with diabetes mellitus.
Topics: Adult; Aged; Aortic Valve Insufficiency; Appetite Depressants; Cohort Studies; Databases, Factual; D | 2010 |
How can benfluorex-related heart valve disease be identified by echocardiography?
Topics: Aortic Valve Insufficiency; Appetite Depressants; Echocardiography, Doppler, Color; Female; Fenflura | 2011 |
Mitral bioprosthesis hypertrophic scaring and native aortic valve fibrosis during benfluorex therapy.
Topics: Adult; Aortic Valve; Bioprosthesis; Cicatrix, Hypertrophic; Female; Fenfluramine; Fibrosis; Heart Va | 2012 |
Increased risk of left heart valve regurgitation associated with benfluorex use in patients with diabetes mellitus: a multicenter study.
Topics: Aged; Aortic Valve Insufficiency; Appetite Depressants; Diabetes Mellitus; Echocardiography; Europe; | 2012 |
Benfluorex: lesions on a bioprosthetic heart valve too.
Topics: Adult; Aortic Valve Insufficiency; Appetite Depressants; Bioprosthesis; Device Removal; Drug Adminis | 2012 |
Valvular heart disease in a patient taking benfluorex.
Topics: Female; Fenfluramine; Glucose Intolerance; Humans; Middle Aged; Mitral Valve Insufficiency; Tricuspi | 2006 |