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benfluorex and Body Weight

benfluorex has been researched along with Body Weight in 14 studies

Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.

Research Excerpts

ExcerptRelevanceReference
"3 ng/mL, means +/- SE), the clinical and metabolic effects of benfluorex (B), a lipid-lowering drug able to improve insulin sensitivity."9.08Benfluorex in obese noninsulin dependent diabetes mellitus patients poorly controlled by insulin: a double blind study versus placebo. ( Camisasca, R; Cassisa, C; Pacchioni, M; Piatti, PM; Pontiroli, AE; Pozza, G, 1996)
"3 ng/mL, means +/- SE), the clinical and metabolic effects of benfluorex (B), a lipid-lowering drug able to improve insulin sensitivity."5.08Benfluorex in obese noninsulin dependent diabetes mellitus patients poorly controlled by insulin: a double blind study versus placebo. ( Camisasca, R; Cassisa, C; Pacchioni, M; Piatti, PM; Pontiroli, AE; Pozza, G, 1996)
" Body weight, insulin, and leptin were decreased (p < 0."3.76MR molecular imaging of aortic angiogenesis. ( Cai, K; Caruthers, SD; Huang, W; Lanza, GM; Wickline, SA; Williams, TA; Winter, PM; Zhang, H, 2010)
"It has been reported that benfluorex ameliorates the insulin resistance induced by high-fat feeding when its administration is initiated at the same time as the change in diet."3.70Benfluorex improves muscle insulin responsiveness in middle-aged rats previously subjected to long-term high-fat feeding. ( Gumà, A; Muñoz, P; Palacín, M; Sevilla, L; Testar, X; Zorzano, A, 1999)
" Treatment once a day for 14 days with 25 mg benfluorex per kg body weight lowered body weight, decreased circulating insulin and resulted in an increase in hepatic glycogen."3.68Effects of chronic benfluorex treatment on the activities of key enzymes of hepatic carbohydrate metabolism in old Sprague-Dawley rats. ( Geelen, MJ; Schmitz, MG; Tielens, AG; van den Heuvel, JM, 1993)
"Rats of the JCR:LA-corpulent strain were treated with benfluorex daily at a dose of 25 mg/kg body weight."3.68Decreased serum lipids, serum insulin and triacylglycerol synthesis in adipose tissue of JCR:LA-corpulent rats treated with benfluorex. ( al-Sieni, AI; Brindley, DN; Hales, P; Russell, JC, 1991)
"(1) Rats were fed on diets enriched with sucrose, beef tallow or corn oil and treated for 11-16 days with 50 mg of benfluorex per kg of body weight."3.67Effects of chronic administration of benfluorex to rats on the metabolism of corticosterone, glucose, triacylglycerols, glycerol and fatty acid. ( Akester, H; Brindley, DN; Derrick, GP; Finnerty, C; Irvine, CD; Macdonald, IA; Patmore, RD; Saxton, J; Spencer, H; Yule-Smith, A, 1988)
"Benfluorex + insulin is a valid alternative for obese patients who remain poorly controlled despite insulin or who require high doses of insulin."2.69Added benfluorex in obese insulin-requiring type 2 diabetes. ( Bauduceau, B; Brun, JM; Guillon-Metz, F; Leutenegger, M; Martin, C; Nicolino-Peltier, C; Richard, JL; Vannereau, D, 1998)
"Benfluorex-treated animals showed significant decreases in glucose intolerance, hyperinsulinemia, hypertriglyceridemia, hypercholesterolemia, and plasma LDL- and VLDL-cholesterol, with no evidence of aortic atheroma."1.30Metabolic and anti-atherogenic effects of long-term benfluorex in dyslipidemic insulin-resistant sand rats (Psammomys obesus). ( Bennani, N; El Madani, T; Hadjiisky, P; Marquié, G; Pieraggi, MT; Ravel, D; Seguin, L; Solera, ML, 1998)
"Benfluorex treatment and pair feeding decreased serum triacylglycerol concentrations by about 50%; there was a preferential loss of triacylglycerols containing longer chain fatty acids in the males, whereas this selectivity was not seen in the females."1.29Effects of benfluorex on serum triacylglycerols and insulin sensitivity in the corpulent rat. ( Brindley, DN; Dolphin, PJ; Graham, SE; Russell, JC, 1996)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19904 (28.57)18.7374
1990's9 (64.29)18.2507
2000's0 (0.00)29.6817
2010's1 (7.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cai, K1
Caruthers, SD1
Huang, W1
Williams, TA1
Zhang, H1
Wickline, SA1
Lanza, GM1
Winter, PM1
Glikmanas, M1
Tielens, AG1
van den Heuvel, JM1
Schmitz, MG1
Geelen, MJ1
Pontiroli, AE1
Pacchioni, M1
Piatti, PM1
Cassisa, C1
Camisasca, R1
Pozza, G1
Russell, JC2
Graham, SE1
Dolphin, PJ1
Brindley, DN3
Fields, M1
Lewis, CG1
Leutenegger, M1
Bauduceau, B1
Brun, JM2
Guillon-Metz, F1
Martin, C1
Nicolino-Peltier, C1
Richard, JL1
Vannereau, D1
Marquié, G1
El Madani, T1
Solera, ML1
Pieraggi, MT1
Hadjiisky, P1
Ravel, D1
Seguin, L1
Bennani, N1
Sevilla, L1
Gumà, A1
Muñoz, P1
Testar, X1
Palacín, M1
Zorzano, A1
Asmal, AC1
Leary, WP1
Deppe, W1
Lockett, CJ1
Hales, P1
al-Sieni, AI1
Akester, H1
Derrick, GP1
Irvine, CD1
Patmore, RD1
Spencer, H1
Yule-Smith, A1
Finnerty, C1
Saxton, J1
Macdonald, IA1
Ranquin, R1

Trials

4 trials available for benfluorex and Body Weight

ArticleYear
Benfluorex in obese noninsulin dependent diabetes mellitus patients poorly controlled by insulin: a double blind study versus placebo.
    The Journal of clinical endocrinology and metabolism, 1996, Volume: 81, Issue:10

    Topics: 3-Hydroxybutyric Acid; Appetite Depressants; Body Weight; C-Peptide; Diabetes Mellitus; Diabetes Mel

1996
Added benfluorex in obese insulin-requiring type 2 diabetes.
    Diabetes & metabolism, 1998, Volume: 24, Issue:1

    Topics: Adolescent; Adult; Aged; Blood Glucose; Body Weight; C-Peptide; Diabetes Mellitus; Diabetes Mellitus

1998
[Antidiabetic efficacy of benfluorex. Clinical data].
    Presse medicale (Paris, France : 1983), 1992, Sep-09, Volume: 21, Issue:28

    Topics: Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Female; Fenfluramine; Humans; Hypolipidemic A

1992
Effects of benfluorex on patients with endogenous hypertriglyceridaemia.
    Current medical research and opinion, 1987, Volume: 10, Issue:8

    Topics: Adult; Aged; Body Weight; Double-Blind Method; Female; Fenfluramine; Humans; Hyperlipidemias; Hypoli

1987

Other Studies

10 other studies available for benfluorex and Body Weight

ArticleYear
MR molecular imaging of aortic angiogenesis.
    JACC. Cardiovascular imaging, 2010, Volume: 3, Issue:8

    Topics: Animals; Aorta; Appetite Depressants; Atherosclerosis; Body Weight; Cholesterol; Disease Models, Ani

2010
[Efficacy of benfluorex in the treatment of multiple metabolic overloads: preliminary results concerning 1609 cases].
    Journees annuelles de diabetologie de l'Hotel-Dieu, 1980

    Topics: Body Weight; Carbohydrate Metabolism; Fenfluramine; Humans; Hypolipidemic Agents; Lipid Metabolism;

1980
Effects of chronic benfluorex treatment on the activities of key enzymes of hepatic carbohydrate metabolism in old Sprague-Dawley rats.
    Biochemical pharmacology, 1993, Nov-02, Volume: 46, Issue:9

    Topics: Aging; Animals; Body Weight; Fenfluramine; Glucose; Glycogen; Insulin; Liver; Male; Phosphoenolpyruv

1993
Effects of benfluorex on serum triacylglycerols and insulin sensitivity in the corpulent rat.
    Canadian journal of physiology and pharmacology, 1996, Volume: 74, Issue:8

    Topics: Animals; Body Weight; Disease Models, Animal; Eating; Female; Fenfluramine; Hypolipidemic Agents; In

1996
Benfluorex, a hypotriglyceridemic drug, reduces lipid peroxidation and alleviates adverse metabolic complications of copper deficiency.
    Nutrition (Burbank, Los Angeles County, Calif.), 1997, Volume: 13, Issue:10

    Topics: Amylases; Analysis of Variance; Animals; Body Weight; Cohort Studies; Copper; Diet; Fasting; Fenflur

1997
Metabolic and anti-atherogenic effects of long-term benfluorex in dyslipidemic insulin-resistant sand rats (Psammomys obesus).
    Life sciences, 1998, Volume: 63, Issue:1

    Topics: Animal Nutritional Physiological Phenomena; Animals; Aorta; Arteriosclerosis; Body Weight; Cholester

1998
Benfluorex improves muscle insulin responsiveness in middle-aged rats previously subjected to long-term high-fat feeding.
    Life sciences, 1999, Volume: 64, Issue:1

    Topics: Aging; Animals; Biological Transport; Blood Glucose; Blotting, Northern; Body Weight; Deoxyglucose;

1999
The effects of benfluramate on carbohydrate metabolism in obesity.
    Research communications in chemical pathology and pharmacology, 1977, Volume: 18, Issue:1

    Topics: Adult; Blood Glucose; Body Weight; Carbohydrate Metabolism; Female; Fenfluramine; Humans; Kinetics;

1977
Decreased serum lipids, serum insulin and triacylglycerol synthesis in adipose tissue of JCR:LA-corpulent rats treated with benfluorex.
    Biochimica et biophysica acta, 1991, Aug-20, Volume: 1085, Issue:1

    Topics: Adipose Tissue; Animals; Body Weight; Feeding Behavior; Female; Fenfluramine; Glucose; Hormones; Hyp

1991
Effects of chronic administration of benfluorex to rats on the metabolism of corticosterone, glucose, triacylglycerols, glycerol and fatty acid.
    Biochemical pharmacology, 1988, Feb-15, Volume: 37, Issue:4

    Topics: Animals; Appetite Depressants; Blood Glucose; Body Weight; Corticosterone; Eating; Fatty Acids; Fenf

1988