benfluorex has been researched along with Aortic Valve Insufficiency in 11 studies
Aortic Valve Insufficiency: Pathological condition characterized by the backflow of blood from the ASCENDING AORTA back into the LEFT VENTRICLE, leading to regurgitation. It is caused by diseases of the AORTIC VALVE or its surrounding tissue (aortic root).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Benfluorex was withdrawn from European markets in June 2010 after reports of an association with heart valve lesions." | 5.38 | Increased risk of left heart valve regurgitation associated with benfluorex use in patients with diabetes mellitus: a multicenter study. ( Arnalsteen, E; Boulanger, J; Donal, E; Ederhy, S; Ennezat, PV; Garban, T; Jeu, A; Jobic, Y; Maréchaux, S; Réant, P; Rusinaru, D; Tribouilloy, C, 2012) |
| "Adjusted RR for mitral insufficiency and aortic insufficiency admissions were 2." | 5.36 | Benfluorex and valvular heart disease: a cohort study of a million people with diabetes mellitus. ( Allemand, H; Fagot, JP; Montastruc, JL; Neumann, A; Païta, M; Ricordeau, P; Simon, D; Tuppin, P; Weill, A, 2010) |
| "Benfluorex was withdrawn from European markets in June 2010 after reports of an association with heart valve lesions." | 1.38 | Increased risk of left heart valve regurgitation associated with benfluorex use in patients with diabetes mellitus: a multicenter study. ( Arnalsteen, E; Boulanger, J; Donal, E; Ederhy, S; Ennezat, PV; Garban, T; Jeu, A; Jobic, Y; Maréchaux, S; Réant, P; Rusinaru, D; Tribouilloy, C, 2012) |
| "Adjusted RR for mitral insufficiency and aortic insufficiency admissions were 2." | 1.36 | Benfluorex and valvular heart disease: a cohort study of a million people with diabetes mellitus. ( Allemand, H; Fagot, JP; Montastruc, JL; Neumann, A; Païta, M; Ricordeau, P; Simon, D; Tuppin, P; Weill, A, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 11 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Trinh, NTH | 1 |
| Solé, E | 1 |
| Benkebil, M | 1 |
| Nicot, P | 1 |
| Frachon, I | 1 |
| Hill, C | 1 |
| Tribouilloy, C | 5 |
| Maréchaux, S | 4 |
| Jobic, Y | 4 |
| Jeu, A | 3 |
| Ederhy, S | 2 |
| Donal, E | 2 |
| Réant, P | 2 |
| Arnalsteen, E | 2 |
| Boulanger, J | 2 |
| Garban, T | 2 |
| Ennezat, PV | 4 |
| Andréjak, M | 3 |
| Rusinaru, D | 4 |
| Borer, JS | 1 |
| Plurien, F | 1 |
| Bruneval, P | 2 |
| Iung, B | 1 |
| Bellemin, JP | 1 |
| Senellart, F | 1 |
| Arnaud-Crozat, E | 1 |
| Ramadan, R | 1 |
| Obadia, JF | 1 |
| Touati, G | 1 |
| Fleury, JP | 1 |
| Weill, A | 1 |
| Païta, M | 1 |
| Tuppin, P | 1 |
| Fagot, JP | 1 |
| Neumann, A | 1 |
| Simon, D | 1 |
| Ricordeau, P | 1 |
| Montastruc, JL | 1 |
| Allemand, H | 1 |
2 reviews available for benfluorex and Aortic Valve Insufficiency
| Article | Year |
|---|---|
[About the settlement of litigations concerning the harm caused by benfluorex (Mediator®)].
Topics: Aortic Valve Insufficiency; Appetite Depressants; Causality; Compensation and Redress; Cross-Section | 2013 |
[Benfluorex and valvular heart disease].
Topics: Aortic Valve Insufficiency; Appetite Depressants; Cohort Studies; Cross-Sectional Studies; Echocardi | 2011 |
9 other studies available for benfluorex and Aortic Valve Insufficiency
| Article | Year |
|---|---|
Benefits of combining change-point analysis with disproportionality analysis in pharmacovigilance signal detection.
Topics: Adverse Drug Reaction Reporting Systems; Aortic Valve Insufficiency; Appetite Depressants; Data Inte | 2019 |
Frequency of drug-induced valvular heart disease in patients previously exposd to benfluorex: a multicentre prospective study.
Topics: Analysis of Variance; Aortic Valve Insufficiency; Appetite Depressants; Case-Control Studies; Diabet | 2013 |
Drug-induced valve disease and considerations of benefit versus risk.
Topics: Aortic Valve Insufficiency; Appetite Depressants; Female; Fenfluramine; Humans; Hypolipidemic Agents | 2013 |
Calcifications in benfluorex-induced valve heart disease: a misknown association.
Topics: Aged; Aortic Valve Insufficiency; Appetite Depressants; Calcinosis; Fenfluramine; Heart Valve Diseas | 2015 |
Operative finding of aortic cusp prolapse in benfluorex-induced aortic regurgitation.
Topics: Adult; Aged; Aortic Valve; Aortic Valve Insufficiency; Aortic Valve Prolapse; Appetite Depressants; | 2015 |
Benfluorex and valvular heart disease: a cohort study of a million people with diabetes mellitus.
Topics: Adult; Aged; Aortic Valve Insufficiency; Appetite Depressants; Cohort Studies; Databases, Factual; D | 2010 |
How can benfluorex-related heart valve disease be identified by echocardiography?
Topics: Aortic Valve Insufficiency; Appetite Depressants; Echocardiography, Doppler, Color; Female; Fenflura | 2011 |
Increased risk of left heart valve regurgitation associated with benfluorex use in patients with diabetes mellitus: a multicenter study.
Topics: Aged; Aortic Valve Insufficiency; Appetite Depressants; Diabetes Mellitus; Echocardiography; Europe; | 2012 |
Benfluorex: lesions on a bioprosthetic heart valve too.
Topics: Adult; Aortic Valve Insufficiency; Appetite Depressants; Bioprosthesis; Device Removal; Drug Adminis | 2012 |