bendroflumethiazide has been researched along with Hypokalemia in 24 studies
Bendroflumethiazide: A thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)
bendroflumethiazide : A sulfonamide consisting of 7-sulfamoyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide in which the hydrogen at position 6 is substituted by a trifluoromethyl group and that at position 3 is substituted by a benzyl group.
Hypokalemia: Abnormally low potassium concentration in the blood. It may result from potassium loss by renal secretion or by the gastrointestinal route, as by vomiting or diarrhea. It may be manifested clinically by neuromuscular disorders ranging from weakness to paralysis, by electrocardiographic abnormalities (depression of the T wave and elevation of the U wave), by renal disease, and by gastrointestinal disorders. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The beta adrenergic blocking drug, timolol, tended to correct the hypokalemia of short-term bendrofluazide treatment in 6 healthy male subjects and although the effect was small it was significant." | 9.04 | Amelioration of bendrofluazide-induced hypokalemia by timolol. ( Davies, DL; Fraser, R; Hettiarachchi, J; Ramsay, LE; Watson, WS, 1977) |
| "Twelve patients with essential hypertension who were already on treatment with the long-acting calcium antagonist amlodipine (5 mg once daily) were entered into a double-blind, randomized crossover study of the addition of one month's treatment with either bendrofluazide (5 mg once daily) or matching placebo." | 5.07 | A double-blind crossover study of the effect of concomitant diuretic therapy in hypertensive patients treated with amlodipine. ( Buckley, MG; Cappuccio, FP; MacGregor, GA; Markandu, ND; Miller, MA; Sagnella, GA; Singer, DR, 1991) |
| "High doses of inhaled albuterol produce substantial improvements in bronchodilatation but are associated with dose-related systemic side effects including hypokalemia and hypomagnesemia." | 5.06 | Prior treatment with diuretic augments the hypokalemic and electrocardiographic effects of inhaled albuterol. ( Lipworth, BJ; McDevitt, DG; Struthers, AD, 1989) |
| "The beta adrenergic blocking drug, timolol, tended to correct the hypokalemia of short-term bendrofluazide treatment in 6 healthy male subjects and although the effect was small it was significant." | 5.04 | Amelioration of bendrofluazide-induced hypokalemia by timolol. ( Davies, DL; Fraser, R; Hettiarachchi, J; Ramsay, LE; Watson, WS, 1977) |
| " These complications may be mitigated with careful monitoring, dosage adjustment, and replacement of electrolyte losses." | 2.41 | Diuretic complications. ( Greenberg, A, 2000) |
| "Rhabdomyolysis is a severe condition with an incidence of 28% in hypokalaemic patients." | 1.40 | [Rhabdomyolysis caused by thiazid-induced hypokalaemia]. ( Bach, PT; Raaber, N, 2014) |
| "Flecainide has been shown to reduce salt absorption in animal bowel." | 1.34 | Flecainide cardiotoxicity precipitated by electrolyte imbalance. Caution with thiazide diuretics. ( Khavandi, A; Walker, PR, 2007) |
| "Amiloride was disproportionately potent in lowering serum bicarbonate, and the data do not suggest that these drugs elevate plasma potassium simply by correcting metabolic alkalosis." | 1.26 | Amiloride, spironolactone, and potassium chloride in thiazide-treated hypertensive patients. ( Fraser, R; Hettiarachchi, J; Morton, JJ; Ramsay, LE, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (66.67) | 18.7374 |
| 1990's | 3 (12.50) | 18.2507 |
| 2000's | 3 (12.50) | 29.6817 |
| 2010's | 2 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bach, PT | 1 |
| Raaber, N | 1 |
| Chong, SJ | 1 |
| Howard, KA | 1 |
| Knox, C | 1 |
| LYON, AF | 1 |
| DEGRAFF, AC | 1 |
| GOSFIELD, E | 1 |
| GILLENWATER, J | 1 |
| Clayton, JA | 1 |
| Rodgers, S | 1 |
| Blakey, J | 1 |
| Avery, A | 1 |
| Hall, IP | 1 |
| Khavandi, A | 1 |
| Walker, PR | 1 |
| Dige-Petersen, H | 1 |
| Hvidt, S | 1 |
| Struthers, AD | 3 |
| Whitesmith, R | 1 |
| Reid, JL | 1 |
| Toner, JM | 1 |
| Ramsay, LE | 4 |
| Hettiarachchi, J | 2 |
| Fraser, R | 2 |
| Morton, JJ | 1 |
| Chataway, SJ | 1 |
| Mumford, CJ | 1 |
| Ironside, JW | 1 |
| Greenberg, A | 1 |
| Davies, DL | 1 |
| Watson, WS | 1 |
| Arif, MA | 1 |
| Eaton, S | 1 |
| Boyle, P | 1 |
| Ramsay, MH | 1 |
| Cappuccio, FP | 1 |
| Markandu, ND | 1 |
| Singer, DR | 1 |
| Buckley, MG | 1 |
| Miller, MA | 1 |
| Sagnella, GA | 1 |
| MacGregor, GA | 1 |
| Lipworth, BJ | 2 |
| McDevitt, DG | 2 |
| Forrester, TE | 1 |
| Grell, GA | 1 |
| Petri, M | 1 |
| Cumber, P | 1 |
| Grimes, L | 1 |
| Treby, D | 1 |
| Bryant, R | 1 |
| Rawlins, D | 1 |
| Ising, H | 1 |
| Güttler, F | 1 |
| Pedersen, A | 1 |
| Fichman, MP | 1 |
| Vorherr, H | 1 |
| Kleeman, CR | 1 |
| Telfer, N | 1 |
| Condon, JR | 1 |
| Nassim, R | 1 |
1 review available for bendroflumethiazide and Hypokalemia
| Article | Year |
|---|---|
Diuretic complications.
Topics: Acid-Base Equilibrium; Antihypertensive Agents; Bendroflumethiazide; Cardiovascular Diseases; Diuret | 2000 |
6 trials available for bendroflumethiazide and Hypokalemia
| Article | Year |
|---|---|
Bendroflumethiazid and sweat electrolytes.
Topics: Adult; Bendroflumethiazide; Electrolytes; Female; Humans; Hypokalemia; Hyponatremia; Potassium; Sodi | 1967 |
Prior thiazide diuretic treatment increases adrenaline-induced hypokalaemia.
Topics: Adult; Bendroflumethiazide; Blood Pressure; Clinical Trials as Topic; Diuretics; Electrocardiography | 1983 |
Amelioration of bendrofluazide-induced hypokalemia by timolol.
Topics: Bendroflumethiazide; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Heart Rate; Huma | 1977 |
A double-blind crossover study of the effect of concomitant diuretic therapy in hypertensive patients treated with amlodipine.
Topics: Adult; Amlodipine; Bendroflumethiazide; Blood Pressure; Calcium Channel Blockers; Double-Blind Metho | 1991 |
Hypokalemic and ECG sequelae of combined beta-agonist/diuretic therapy. Protection by conventional doses of spironolactone but not triamterene.
Topics: Adult; Albuterol; Bendroflumethiazide; Drug Synergism; Drug Therapy, Combination; Electrocardiograph | 1990 |
Prior treatment with diuretic augments the hypokalemic and electrocardiographic effects of inhaled albuterol.
Topics: Administration, Inhalation; Adult; Albuterol; Bendroflumethiazide; Blood Pressure; Creatinine; Diure | 1989 |
17 other studies available for bendroflumethiazide and Hypokalemia
| Article | Year |
|---|---|
[Rhabdomyolysis caused by thiazid-induced hypokalaemia].
Topics: Adult; Bendroflumethiazide; Female; Humans; Hypokalemia; Rhabdomyolysis; Thiazides | 2014 |
Hypokalaemia and drinking green tea: a literature review and report of 2 cases.
Topics: Aged; Amlodipine; Antihypertensive Agents; Bendroflumethiazide; Drinking Behavior; Female; Humans; H | 2016 |
DIURETIC THERAPY. VI. METABOLIC COMPLICATIONS OF THIAZIDE THERAPY AND THEIR CORRECTION.
Topics: Bendroflumethiazide; Blood; Blood Urea Nitrogen; Diuretics; Humans; Hydrochlorothiazide; Hyperglycem | 1964 |
SIX-MONTH DOUBLE-BLIND STUDY OF BENZOTHIADIAZINE DRUG EFFECTS ON HYPERTENSION AND SELECTED BLOOD CHEMISTRIES.
Topics: Bendroflumethiazide; Biomedical Research; Blood Chemical Analysis; Double-Blind Method; Drug Therapy | 1965 |
Thiazide diuretic prescription and electrolyte abnormalities in primary care.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Bendroflumethiazide; Cross-Sectional Studies; Family Pr | 2006 |
Flecainide cardiotoxicity precipitated by electrolyte imbalance. Caution with thiazide diuretics.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bendroflumethiazide; Diuretics; Drug Interactions; Ele | 2007 |
Long-term thiazide diuretics.
Topics: Aged; Bendroflumethiazide; Female; Gout; Humans; Hypokalemia; Male; Middle Aged; Time Factors | 1981 |
Thiazide-induced hypokalaemia; prevalence higher in women.
Topics: Aged; Bendroflumethiazide; Diuretics; Female; Humans; Hypokalemia; Male; Middle Aged; Potassium; Sex | 1984 |
Amiloride, spironolactone, and potassium chloride in thiazide-treated hypertensive patients.
Topics: Adult; Aldosterone; Amiloride; Angiotensin II; Bendroflumethiazide; Bicarbonates; Blood Pressure; Di | 1980 |
Self-induced myopathy.
Topics: Antihypertensive Agents; Bendroflumethiazide; Candy; Female; Glycyrrhiza; Humans; Hypokalemia; Middl | 1997 |
The effect of oral potassium supplements on plasma potassium in normokalaemic and hypokalaemic patients.
Topics: Administration, Oral; Bendroflumethiazide; Female; Humans; Hypokalemia; Male; Middle Aged; Potassium | 1977 |
Factors influencing serum potassium in treated hypertension.
Topics: Adult; Aged; Bendroflumethiazide; Creatinine; Diuretics; Female; Humans; Hypertension; Hypokalemia; | 1977 |
Changes in red cell sodium content and blood pressure levels with potassium supplementation in black hypertensive patients.
Topics: Bendroflumethiazide; Black People; Blood Pressure; Drug Therapy, Combination; Erythrocytes; Female; | 1988 |
The metabolic effects of thiazide therapy in the elderly: a population study.
Topics: Aged; Bendroflumethiazide; Blood Glucose; Female; Humans; Hypokalemia; Magnesium; Male; Potassium; S | 1986 |
Baseosis and hypopotassaemia in chronic hypercapnia: the influence of chloride and potassium intake during administration of diuretics.
Topics: Adult; Alkalosis; Ammonium Chloride; Bendroflumethiazide; Bicarbonates; Carbon Dioxide; Chlorides; E | 1973 |
Diuretic-induced hyponatremia.
Topics: Adult; Aged; Alkalosis; Bendroflumethiazide; Biological Assay; Blood Urea Nitrogen; Bromine; Carbon | 1971 |
Hypophosphataemia and hypokalaemia.
Topics: Bendroflumethiazide; Calcium; Calcium Metabolism Disorders; Humans; Hypokalemia; Phosphates | 1970 |