bendroflumethiazide has been researched along with Hypertension in 296 studies
Bendroflumethiazide: A thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)
bendroflumethiazide : A sulfonamide consisting of 7-sulfamoyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide in which the hydrogen at position 6 is substituted by a trifluoromethyl group and that at position 3 is substituted by a benzyl group.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| "5 mg/day and potassium chloride was compared with that of enalapril 10 mg/day and amlodipine 5 mg/day in patients with mild to moderate primary hypertension." | 9.12 | Efficacy and safety of 24 weeks of therapy with bendroflumethiazide 1.25 mg/day or 2.5 mg/day and potassium chloride compared with enalapril 10 mg/day and amlodipine 5 mg/day in patients with mild to moderate primary hypertension : a multicentre, randomis ( Borrild, N; Rasmussen, S; Vang Andersen, J, 2006) |
| " It is not known if subjects with a high ratio have aldosteronism or aldosterone-sensitive hypertension is debated but it is important to know whether spironolactone is superior to other diuretics such as bendroflumethiazide in this setting." | 9.12 | Does the aldosterone:renin ratio predict the efficacy of spironolactone over bendroflumethiazide in hypertension? A clinical trial protocol for RENALDO (RENin-ALDOsterone) study. ( Alhashmi, K; Connell, JM; Ford, I; MacDonald, TM; McInnes, GT; McMahon, AD; Parthasarathy, HK; Struthers, AD, 2007) |
| " Doxazosin, a selective alpha(1)-adrenergic blocker, in addition to lowering blood pressure, has been shown to have positive effects on glucose metabolism and lipid profiles in patients with hypertension." | 9.11 | Doxazosin versus bendrofluazide: a comparison of the metabolic effects in British South Asians with hypertension. ( Collins, B; Hobbs, FR; Khan, T, 2005) |
| "The association between change in glucose metabolism and change in skeletal muscle magnesium (Mg) concentration induced by antihypertensive treatment was evaluated in 37 patients with essential hypertension randomly treated with either lisinopril or bendrofluazide." | 9.10 | Skeletal muscle magnesium content is correlated with plasma glucose concentration in patients with essential hypertension treated with lisinopril or bendrofluazide. ( Andersson, PE; Haenni, A; Lind, L; Lithell, H; Reneland, R, 2002) |
| "The therapeutic efficacy of long acting diltiazem 300 mg od (Tildiem LA) was compared with sustained release nifedipine 20 mg bd and bendrofluazide 5 mg od in a multicentre study with 230 patients diagnosed with mild to moderate essential hypertension, with 77, 77 and 76 randomized to the diltiazem, nifedipine SR and bendrofluazide groups respectively." | 9.07 | A comparative study of long acting diltiazem (Tildiem LA) with sustained release nifedipine (nifedipine SR) and bendrofluazide in the treatment of mild to moderate hypertension. ( Belgrave, GP; Hosie, J; Nasar, MA; Walters, EG, 1994) |
| "The acute effects on urinary electrolyte excretion and plasma potassium were compared of the anti-hypertensive dihydrofuropyridine cicletanine with the thiazide bendrofluazide in 6 patients with uncomplicated essential hypertension." | 9.06 | A comparison of the acute effects of cicletanine and bendrofluazide on urinary electrolytes and plasma potassium in essential hypertension. ( MacGregor, GA; Markandu, ND; Singer, DR; Sugden, AL, 1990) |
| "The efficacy of sustained-release propranolol 160 mg (Inderal LA), bendrofluazide 5 mg and the combination preparation Inderex (bendrofluazide 5 mg and Inderal LA) in the treatment of hypertension was investigated." | 9.06 | Treatment of hypertension with a fixed ratio combination of long-acting propranolol and bendrofluazide, and influence of age of the subject. ( Davis, JM; Herrick, AL; Weir, RJ, 1989) |
| "The effects of verapamil and bendrofluazide used singly and in combination were examined in patients with primary hypertension in a patient blind, partly observer blind placebo controlled study of parallel group design; there were ten subjects in each arm of the trial." | 9.06 | Verapamil and bendrofluazide in the treatment of hypertension: a controlled study of effectiveness alone and in combination. ( Benjamin, N; Phillips, RJ; Robinson, BF, 1988) |
| "A sample of 500 patients with mild to moderate hypertension, who had been successfully controlled on once daily timolol/bendrofluazide at the end of a 3-month general practice study, was followed up after approximately 1 year of treatment." | 9.06 | Long-term follow-up of 500 patients with mild to moderate hypertension who had successfully completed a 3-month general practice study of a timolol-bendrofluazide combination ('Prestim'). ( Fairey, IT; Head, AC; Marsh, BT, 1987) |
| "A randomized, double-blind study was undertaken to compare atenolol and captopril as second-step agents in the treatment of essential hypertension resistant to 5 mg bendrofluazide daily." | 9.06 | Comparative efficacy of captopril and atenolol in moderately severe essential hypertension. ( Blake, S; Carey, M, 1986) |
| "The effects of 5 mg bendroflumethiazide plus 15 mmol potassium chloride versus 50 mg hydrochlorothiazide plus 5 mg amiloride on blood pressure and serum electrolytes were investigated in a 12-week, open, randomized study with parallel treatment groups." | 9.06 | The effects of bendroflumethiazide/potassium chloride versus hydrochlorothiazide/amiloride on blood pressure and serum electrolytes in patients with mild to moderate hypertension seen in general practice. ( Bredesgaard, P; Johansen, P; Jørgensen, F, 1986) |
| "Participants in the Medical Research Council treatment trial for mild hypertension are randomly allocated to one of four treatment groups: bendrofluazide, propranolol, or a placebo for either of these drugs." | 9.05 | Adverse reactions to bendrofluazide and propranolol for the treatment of mild hypertension. Report of Medical Research Council Working Party on Mild to Moderate Hypertension. ( , 1981) |
| "1 To compare the efficacy of indapamide with that of bendrofluazide a randomised trial was carried out in twenty patients with essential hypertension." | 9.05 | Indapamide and bendrofluazide: a comparison in the management of essential hypertension. ( Bing, RF; Russell, GI; Swales, JD; Thurston, H, 1981) |
| "The effect of conventional propranolol and bendrofluazide tablets given twice daily has been compared with an equivalent dosage combined in a single capsule given twice daily in fourteen patients with essential hypertension." | 9.05 | Treatment of essential hypertension with a combination of propranolol and bendrofluazide. ( Dawes, PM; Solomon, LR, 1980) |
| "1 Indoramin, an alpha-adrenoreceptor blocking agent has been given as a third agent to patients with severe hypertension treated with adequate doses of a beta-adrenoceptor blocking drug and a thiazide diuretic." | 9.05 | Evaluation of indoramin added to oxprenolol and bendrofluazide as a third agent in severe hypertension. ( Barritt, DW; Kettle, MA; Marshall, AJ, 1980) |
| "The beta-adrenergic blocking drug, timolol, was combined with bendrofluazide in a comparative trial between once and twice daily dosage, conducted on 51 patients suffering from hypertension seen in general practice." | 9.04 | Timolol and bendrofluazide in the management of hypertension in general practice. ( Wheatley, D, 1978) |
| "In patients with uncontrolled hypertension addition of xipamide 20 mg daily to bendrofluazide 5 mg daily produced no significant additive antihypertensive effect, and the 95% confidence limits excluded a clinically important response." | 7.67 | Xipamide: no advantage over bendrofluazide in hypertension. ( Freestone, S; Ramsay, LE, 1984) |
| "Amiloride 40 mg was as effective as the other diuretics." | 6.73 | The spironolactone, amiloride, losartan, and thiazide (SALT) double-blind crossover trial in patients with low-renin hypertension and elevated aldosterone-renin ratio. ( Ashby, MJ; Brown, MJ; Hood, SJ; Taylor, KP, 2007) |
| "Aldosterone antagonism has BP-independent effects on arterial stiffness." | 6.71 | Aldosterone-to-renin ratio, arterial stiffness, and the response to aldosterone antagonism in essential hypertension. ( Feely, J; Mahmud, A, 2005) |
| "Bendroflumethiazide was accompanied by minor but significant elevations in fasting plasma glucose and serum C-peptide." | 6.67 | Enalapril versus bendroflumethiazide in type 2 diabetes complicated by hypertension. ( Dollerup, J; Knudsen, RE; Mogensen, CE; Nielsen, S; Schmitz, A, 1994) |
| "Hypertension is a major risk factor for stroke and heart disease in the elderly." | 6.67 | A double-blind trial of captopril or bendrofluazide in newly diagnosed senile hypertension. ( Hadley, L; Inch, S; Starr, JM; Whalley, LJ; White, A, 1994) |
| "Bendroflumethiazide 5 mg was given to 17 patients with essential hypertension who had persistent mild to moderate hypertension despite treatment with nifedipine slow-release tablets 20 mg bid." | 6.66 | The effects of bendroflumethiazide added to nifedipine in patients with hypertension. ( Beevers, DG; Gill, JS; Zezulka, AV, 1987) |
| "Prazosin appears to be a potent and appropriate third agent." | 6.64 | Evaluation of beta blockade bendrofluazide, and prazosin in severe hypertension. ( Barritt, DW; Heaton, ST; Marshall, AJ; Pocock, J, 1977) |
| "For chlorthalidone, there were four comparisons with other medications, and the summary RR was statistically significant for cardiovascular disease outcomes (RR = 0." | 6.55 | Should we switch from bendrofluazide to chlorthalidone as the initial treatment for hypertension? A review of the available medication. ( Arroll, B; Wallace, H, 2017) |
| " Initial dosage of 1 tablet b." | 5.27 | [Potassium-sparing effect of triamterene in a 3-component combination preparation for the therapy of hypertension]. ( Dittrich, H; Nagler, J, 1986) |
| "6%) patients who required a dosage reduction and 2 (0." | 5.26 | A multi-centre general practice study on the use of a timolol/bendrofluazide combination ('Prestim') in the management of hypertension: preliminary report. ( Head, AC; Langrick, AF, 1981) |
| " In a complementary investigation, 14 patients who completed the 16-weeks' treatment were changed onto a regimen in which the drug dosage remained unchanged but was taken on a once-daily basis for a further 16 weeks to assess the efficacy of once-daily dosing and to monitor any further long-term changes in biochemistry." | 5.26 | A hospital out-patient study of timolol/bendrofluazide combination ('Prestim') in essential hypertension. ( Kubik, MM, 1980) |
| "The aim of this study was to evaluate the effect of baseline heart rate on the efficacy of atenolol-based compared with amlodipine-based therapy in patients with hypertension uncomplicated by coronary heart disease in the ASCOT-BPLA (Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm)." | 5.14 | Baseline heart rate, antihypertensive treatment, and prevention of cardiovascular outcomes in ASCOT (Anglo-Scandinavian Cardiac Outcomes Trial). ( Campbell, NR; Dahlöf, B; Dobson, JE; Poulter, NR; Sever, PS; Wedel, H, 2009) |
| "We examined the effects on insulin sensitivity of captopril either alone or in combination with low-dose bendroflumethiazide (1." | 5.13 | Comparison of effects of combined ACE inhibitor and low-dose thiazide diuretic with ACE inhibitor alone on insulin action in patients with hypertension and Type 2 diabetes: a double-blind crossover study. ( Atkinson, AB; Bell, PM; Browne, J; Ennis, CN; Hunter, SJ; McLaughlin, DM; Sheridan, B, 2008) |
| "5 mg/day and potassium chloride was compared with that of enalapril 10 mg/day and amlodipine 5 mg/day in patients with mild to moderate primary hypertension." | 5.12 | Efficacy and safety of 24 weeks of therapy with bendroflumethiazide 1.25 mg/day or 2.5 mg/day and potassium chloride compared with enalapril 10 mg/day and amlodipine 5 mg/day in patients with mild to moderate primary hypertension : a multicentre, randomis ( Borrild, N; Rasmussen, S; Vang Andersen, J, 2006) |
| " It is not known if subjects with a high ratio have aldosteronism or aldosterone-sensitive hypertension is debated but it is important to know whether spironolactone is superior to other diuretics such as bendroflumethiazide in this setting." | 5.12 | Does the aldosterone:renin ratio predict the efficacy of spironolactone over bendroflumethiazide in hypertension? A clinical trial protocol for RENALDO (RENin-ALDOsterone) study. ( Alhashmi, K; Connell, JM; Ford, I; MacDonald, TM; McInnes, GT; McMahon, AD; Parthasarathy, HK; Struthers, AD, 2007) |
| "Twenty-four patients with hypertension were assigned, in a random crossover fashion, to a sequence of bendroflumethiazide, nifedipine LA and enalapril, each for 4 weeks, followed by a 1-week period of dose omission." | 5.11 | Comparison of the effects of a 7-day period of non-compliance on blood pressure control using three different antihypertensive agents. ( Girvin, BG; Johnston, GD, 2004) |
| " Doxazosin, a selective alpha(1)-adrenergic blocker, in addition to lowering blood pressure, has been shown to have positive effects on glucose metabolism and lipid profiles in patients with hypertension." | 5.11 | Doxazosin versus bendrofluazide: a comparison of the metabolic effects in British South Asians with hypertension. ( Collins, B; Hobbs, FR; Khan, T, 2005) |
| "The association between change in glucose metabolism and change in skeletal muscle magnesium (Mg) concentration induced by antihypertensive treatment was evaluated in 37 patients with essential hypertension randomly treated with either lisinopril or bendrofluazide." | 5.10 | Skeletal muscle magnesium content is correlated with plasma glucose concentration in patients with essential hypertension treated with lisinopril or bendrofluazide. ( Andersson, PE; Haenni, A; Lind, L; Lithell, H; Reneland, R, 2002) |
| "To compare quality of life with the selective beta1-blocker bisoprolol and the thiazide diuretic bendrofluazide in patients with mild to moderate hypertension." | 5.09 | Impact of antihypertensive treatment on quality of life: comparison between bisoprolol and bendrofluazide. ( de Hoon, JN; Van Bortel, LM; van de Ven, LL; Vanmolkot, FH, 1999) |
| "To evaluate the association between skeletal muscle mineral balance and effect of antihypertensive treatment, 37 patients with essential hypertension, randomly treated with either lisinopril or bendrofluazide, were investigated with skeletal muscle biopsies before and after 6 months of treatment." | 5.08 | The blood pressure response to antihypertensive treatment with lisinopril or bendrofluazide is related to the calcium and magnesium contents in skeletal muscle. ( Haenni, A; Lind, L; Lithell, H, 1996) |
| "Combination therapy increased glucose production (compared with captopril alone), indicating hepatic insulin resistance." | 5.08 | Effects of combination therapy with an angiotensin converting enzyme inhibitor and thiazide diuretic on insulin action in essential hypertension. ( Atkinson, AB; Bell, PM; Crothers, E; Ennis, CN; Harper, R; Hunter, SJ; Johnston, GD; Sheridan, B, 1998) |
| "The therapeutic efficacy of long acting diltiazem 300 mg od (Tildiem LA) was compared with sustained release nifedipine 20 mg bd and bendrofluazide 5 mg od in a multicentre study with 230 patients diagnosed with mild to moderate essential hypertension, with 77, 77 and 76 randomized to the diltiazem, nifedipine SR and bendrofluazide groups respectively." | 5.07 | A comparative study of long acting diltiazem (Tildiem LA) with sustained release nifedipine (nifedipine SR) and bendrofluazide in the treatment of mild to moderate hypertension. ( Belgrave, GP; Hosie, J; Nasar, MA; Walters, EG, 1994) |
| "The metabolic effects of lisinopril and bendrofluazide therapy were studied in 61 patients with essential hypertension in a randomized, double-blind study with parallel groups." | 5.07 | Electrolyte changes and metabolic effects of lisinopril/bendrofluazide treatment. Results from a randomized, double-blind study with parallel groups. ( Andersson, PE; Berne, C; Haenni, A; Lind, L; Lithell, H, 1994) |
| "Twelve patients with essential hypertension who were already on treatment with the long-acting calcium antagonist amlodipine (5 mg once daily) were entered into a double-blind, randomized crossover study of the addition of one month's treatment with either bendrofluazide (5 mg once daily) or matching placebo." | 5.07 | A double-blind crossover study of the effect of concomitant diuretic therapy in hypertensive patients treated with amlodipine. ( Buckley, MG; Cappuccio, FP; MacGregor, GA; Markandu, ND; Miller, MA; Sagnella, GA; Singer, DR, 1991) |
| "In a randomized primary prevention trial including 3,234 men with mild to moderate uncomplicated hypertension, the effect of the beta-blocker metoprolol or a thiazide diuretic as an initial antihypertensive therapy was compared regarding the risk of sudden cardiovascular death during a follow-up ranging from 2." | 5.07 | Primary prevention of sudden cardiovascular death in hypertensive patients. Mortality results from the MAPHY Study. ( Barber, H; Berglund, G; Eliasson, K; Elmfeldt, D; Jastrup, B; Karatzas, N; Leer, J; Olsson, G; Tuomilehto, J; Warnold, I, 1991) |
| "The acute effects on urinary electrolyte excretion and plasma potassium were compared of the anti-hypertensive dihydrofuropyridine cicletanine with the thiazide bendrofluazide in 6 patients with uncomplicated essential hypertension." | 5.06 | A comparison of the acute effects of cicletanine and bendrofluazide on urinary electrolytes and plasma potassium in essential hypertension. ( MacGregor, GA; Markandu, ND; Singer, DR; Sugden, AL, 1990) |
| "The efficacy of sustained-release propranolol 160 mg (Inderal LA), bendrofluazide 5 mg and the combination preparation Inderex (bendrofluazide 5 mg and Inderal LA) in the treatment of hypertension was investigated." | 5.06 | Treatment of hypertension with a fixed ratio combination of long-acting propranolol and bendrofluazide, and influence of age of the subject. ( Davis, JM; Herrick, AL; Weir, RJ, 1989) |
| "The effects of verapamil and bendrofluazide used singly and in combination were examined in patients with primary hypertension in a patient blind, partly observer blind placebo controlled study of parallel group design; there were ten subjects in each arm of the trial." | 5.06 | Verapamil and bendrofluazide in the treatment of hypertension: a controlled study of effectiveness alone and in combination. ( Benjamin, N; Phillips, RJ; Robinson, BF, 1988) |
| "A sample of 500 patients with mild to moderate hypertension, who had been successfully controlled on once daily timolol/bendrofluazide at the end of a 3-month general practice study, was followed up after approximately 1 year of treatment." | 5.06 | Long-term follow-up of 500 patients with mild to moderate hypertension who had successfully completed a 3-month general practice study of a timolol-bendrofluazide combination ('Prestim'). ( Fairey, IT; Head, AC; Marsh, BT, 1987) |
| "A randomized, double-blind study was undertaken to compare atenolol and captopril as second-step agents in the treatment of essential hypertension resistant to 5 mg bendrofluazide daily." | 5.06 | Comparative efficacy of captopril and atenolol in moderately severe essential hypertension. ( Blake, S; Carey, M, 1986) |
| "The antihypertensive efficacy of propranolol in the treatment of mild hypertension was significantly impaired in cigarette smokers, whereas that of bendrofluazide was not affected by smoking habit." | 5.06 | The relationship between smoking and the response to anti-hypertensive treatment in mild hypertensives in the Medical Research Council's trial of treatment. ( Brennan, PJ; Greenberg, G; Thompson, SG, 1987) |
| "The effects of 5 mg bendroflumethiazide plus 15 mmol potassium chloride versus 50 mg hydrochlorothiazide plus 5 mg amiloride on blood pressure and serum electrolytes were investigated in a 12-week, open, randomized study with parallel treatment groups." | 5.06 | The effects of bendroflumethiazide/potassium chloride versus hydrochlorothiazide/amiloride on blood pressure and serum electrolytes in patients with mild to moderate hypertension seen in general practice. ( Bredesgaard, P; Johansen, P; Jørgensen, F, 1986) |
| "In 93 patients with hypertension uncontrolled by bendrofluazide 5 mg plus atenolol 100 mg daily, the effects of adding nifedipine (up to 60 mg/day, n = 31), prazosin (up to 20 mg/day, n = 31), or hydralazine (up to 200 mg/day, n = 31) were compared in a 6 month open random parallel group study." | 5.06 | Comparison of nifedipine, prazosin and hydralazine added to treatment of hypertensive patients uncontrolled by thiazide diuretic plus beta-blocker. ( Parnell, L; Ramsay, LE; Waller, PC, 1987) |
| "The antihypertensive effect and metabolic side effects of bendroflumethiazide have been compared with those of propranolol in two randomly selected groups, of 53 previously untreated middle-aged men during 6 years' treatment for mild to moderately severe essential hypertension." | 5.05 | beta-blockers or diuretics in hypertension? A six year follow-up of blood pressure and metabolic side effects. ( Andersson, O; Berglund, G, 1981) |
| "Participants in the Medical Research Council treatment trial for mild hypertension are randomly allocated to one of four treatment groups: bendrofluazide, propranolol, or a placebo for either of these drugs." | 5.05 | Adverse reactions to bendrofluazide and propranolol for the treatment of mild hypertension. Report of Medical Research Council Working Party on Mild to Moderate Hypertension. ( , 1981) |
| "The anti-hypertensive action and tolerability of single daily doses of 80 mg nadolol, or 80 mg nadolol and 5 mg bendroflumethiazide were assessed in 30 subjects with mild or moderate hypertension." | 5.05 | [Evaluation of the antihypertensive effect and tolerability of nadolol administered alone or in association with bendroflumethiazide]. ( Gragnoli, G; Kristodhullu, A; Mondillo, S; Righi, GA; Turchetti, V, 1984) |
| "A within-patient randomized, double-blind, crossover study was performed to investigate mechanisms of action of bendroflumethiazide in mild essential hypertension." | 5.05 | Antihypertensive action of bendroflumethiazide: increased prostacyclin production? ( Dollery, CT; Friedman, LA; Hensby, CN; Webster, J, 1980) |
| "In a double-blind cross-over multicentre study lasting for 16 weeks, the antihypertensive effect of atenolol (100 mg once a day) was compared with that of methyldopa (250 mg thrice a day) in 48 patients with mild to moderately severe hypertension." | 5.05 | Antihypertensive effect of atenolol (100 mg once a day) and methyldopa (250 mg thrice a day). A double-blind cross-over multicentre study. ( Brøns, M; Christensen, CK; Geday, E; Jacobsen, FK; Jensen, SN; Kristensen, BO; Linde, NC, 1981) |
| "1 To compare the efficacy of indapamide with that of bendrofluazide a randomised trial was carried out in twenty patients with essential hypertension." | 5.05 | Indapamide and bendrofluazide: a comparison in the management of essential hypertension. ( Bing, RF; Russell, GI; Swales, JD; Thurston, H, 1981) |
| "The effect of conventional propranolol and bendrofluazide tablets given twice daily has been compared with an equivalent dosage combined in a single capsule given twice daily in fourteen patients with essential hypertension." | 5.05 | Treatment of essential hypertension with a combination of propranolol and bendrofluazide. ( Dawes, PM; Solomon, LR, 1980) |
| "1 Indoramin, an alpha-adrenoreceptor blocking agent has been given as a third agent to patients with severe hypertension treated with adequate doses of a beta-adrenoceptor blocking drug and a thiazide diuretic." | 5.05 | Evaluation of indoramin added to oxprenolol and bendrofluazide as a third agent in severe hypertension. ( Barritt, DW; Kettle, MA; Marshall, AJ, 1980) |
| "Nine patients with essential hypertension treated with bendroflumethiazide were given captopril 25 mg orally on three occasions to study the pharmacokinetics and blood pressure effects." | 5.05 | Pharmacokinetics of captopril and its effects on blood pressure during acute and chronic administration and in relation to food intake. ( Kågedal, B; Karlberg, BE; Larsson, R; Ohman, KP, 1985) |
| "Fifty-five patients with mild to moderate, renal or essential hypertension were admitted to a double blind cross-over trial of 18 weeks, involving treatment periods with placebo, the thiazide bendrofluazide (15 mg daily) and the beta blocker atenolol (600 mg daily)." | 5.04 | Relative value of beta blockers and thiazides for initiating antihypertensive therapy. Beta blockers or thiazides in hypertension. ( Amery, A; De Plaen, JF; Fagard, R; Lijnen, P; Missotten, A, 1976) |
| "Atenolol was compared with five other beta-blockers and a thiazide diuretic in a randomised cross-over trial of once-daily treatment of essential hypertension." | 5.04 | Randomised study of six beta-blockers and a thiazide diuretic in essential hypertension. ( Wilcox, RG, 1978) |
| "The beta-adrenergic blocking drug, timolol, was combined with bendrofluazide in a comparative trial between once and twice daily dosage, conducted on 51 patients suffering from hypertension seen in general practice." | 5.04 | Timolol and bendrofluazide in the management of hypertension in general practice. ( Wheatley, D, 1978) |
| "In 15 patients with moderate to severe hypertension (WHO II--III) atenolol was evaluated against a thiazide diuretic (bendrofluazide) in a single blind crossover study." | 5.04 | [Atenelol and bendrofluazide in the treatment of medium and severe hypertension (preliminary report)]. ( Braendli, B; Bucher, HJ; Nager, F; Truniger, B, 1978) |
| "A randomized double-blind crossover trial of labetalol, bendrofluazide and placebo was carried out in 18 patients with mild to moderate hypertension." | 5.04 | Labetalol and bendrofluazide: comparison of their antihypertensive effects. ( Caterson, RJ; Collett, P; Duggin, GG; Horvath, JS; Kelly, DH; Tiller, DJ, 1979) |
| "The pilot phase of the British multicentre randomized controlled trial of treatment for mild hypertension has shown: (1) that unselected subjects, aged 35-64 years, with mild hypertension are willing to enter and remain in a long-term trial even though asymptomatic; (2) that the differences of mean systolic and mean diastolic pressure achieved between treated and control subjects is sufficient to produce the expected difference in terminating events with the 18000 patients calculated as needed for the full-scale trial; (3) that side effects with the two selected active primary regimens (bendrofluazide and propranolol) are common but mild (no serious side effects or toxic reactions have been reported); (4) that the work load imposed by the trial, though considerable during screening and the initiation of patients into the trial, can largely be taken by specially trained nursing staff, and when screening is completed the trial does not impose a heavy burden of follow-up examinations; (5) that there are no adverse psychological effects caused by alerting asymptomatic people to their raised pressure and enrolling them into a prolonged programme of clinical attendance; (6) that the total costs of carrying out a full-scale trial--estimated at about lb." | 5.04 | Medical Research Council's Treatment Trial for mild hypertension: an interim report. ( Brennan, PJ; Mann, AH; Miall, WE, 1976) |
| "Thiazide and thiazide-like diuretics are widely used in the management of hypertension, but recently the equivalence of hydrochlorothiazide and chlorthalidone for blood pressure (BP) lowering and prevention of cardiovascular disease has been questioned." | 4.88 | Meta-analysis of dose-response relationships for hydrochlorothiazide, chlorthalidone, and bendroflumethiazide on blood pressure, serum potassium, and urate. ( Chaturvedi, N; Hardy, R; Hughes, AD; Peterzan, MA, 2012) |
| " Starting dosage for bendroflumethiazide and lisinopril is 2." | 3.77 | The Hypertension in the Very Elderly Trial (HYVET). Rationale, methodology and comparison with previous trials. ( Amery, A; Bulpitt, CJ; Coope, J; Evans, JG; Fletcher, AE; Lightowlers, S; O'Malley, K; Palmer, A; Potter, J; Sever, P, 1994) |
| "We correlated the BP response to spironolactone 50 mg/day to baseline ARR in 69 hypertensive patients (mean [+/-SD] age 57 +/- 2 years, 65% male), consisting of 39 subjects with long-standing hypertension (4." | 3.73 | Does aldosterone-to-renin ratio predict the antihypertensive effect of the aldosterone antagonist spironolactone? ( Feely, J; Hall, M; Mahgoub, M; Mahmud, A, 2005) |
| "In patients with uncontrolled hypertension addition of xipamide 20 mg daily to bendrofluazide 5 mg daily produced no significant additive antihypertensive effect, and the 95% confidence limits excluded a clinically important response." | 3.67 | Xipamide: no advantage over bendrofluazide in hypertension. ( Freestone, S; Ramsay, LE, 1984) |
| "In the Medical Research Council trial for the treatment of mild hypertension, bendrofluazide showed an unexpected and sizeable benefit compared with propranolol in the reduction of stroke." | 3.67 | Does angiotensin-II protect against strokes? ( Brown, J; Brown, MJ, 1986) |
| "This study was designed to assess the effectiveness of a timolol/bendrofluazide combination (Prestim) in mild to moderate essential hypertension in patients not achieving control of blood pressure on a variety of drugs used alone or in combination (methyldopa, diuretics, beta-blockers, etc." | 3.66 | The use of timolol/bendrofluazide (Prestim) in the treatment of hypertensive patients failing to respond to other antihypertensives. ( Ellis, R; Wood, SJ, 1983) |
| "In patients with hypertension resistant to three or four drugs including a thiazide diuretic substitution of frusemide for the thiazide, or the addition of spironolactone, produced significant reductions in blood pressure and body weight." | 3.66 | Diuretic treatment of resistant hypertension. ( Freestone, S; Ramsay, LE; Silas, JH, 1980) |
| "Iodine metabolism and thyroid hormones in blood were studied in 19 men and 11 women who had been treated with thiazides for arterial hypertension from 1 month to 15 years." | 3.66 | Influence of thiazides on thyroid parameters in man. ( Bech, K; Hansen, JM; Siersbaek-Nielsen, K; Skovsted, L, 1978) |
| "Treatment of patients with type 2 diabetes with Irbesartan decreased urinary excretion of MG-H1, G-H1 and 3-NT, which may result from decreased exposure to these AGEs." | 2.77 | Effect of Irbesartan treatment on plasma and urinary markers of protein damage in patients with type 2 diabetes and microalbuminuria. ( Adaikalakoteswari, A; Parving, HH; Rabbani, N; Rossing, K; Rossing, P; Tarnow, L; Thornalley, PJ, 2012) |
| "Resistant hypertension is a well recognized clinical entity, which has been inadequately researched to date." | 2.76 | Baseline predictors of resistant hypertension in the Anglo-Scandinavian Cardiac Outcome Trial (ASCOT): a risk score to identify those at high-risk. ( Chang, CL; Dahlöf, B; Gupta, AK; Nasothimiou, EG; Poulter, NR; Sever, PS, 2011) |
| "Isolated systolic hypertension is an important risk factor for cardiovascular disease and results primarily from elastic artery stiffening." | 2.74 | Comparison of the effects of antihypertensive agents on central blood pressure and arterial stiffness in isolated systolic hypertension. ( Brown, MJ; Cockcroft, JR; Dhakam, Z; Mackenzie, IS; McEniery, CM; Wilkinson, IB, 2009) |
| "5 mg; n=22), captopril (50 mg twice daily; n=22) or a capsule containing each of the 4 above at one-quarter dosage (n=22) in a parallel group design for 4 weeks." | 2.73 | Low-dose quadruple antihypertensive combination: more efficacious than individual agents--a preliminary report. ( Feely, J; Mahmud, A, 2007) |
| "Amiloride 40 mg was as effective as the other diuretics." | 2.73 | The spironolactone, amiloride, losartan, and thiazide (SALT) double-blind crossover trial in patients with low-renin hypertension and elevated aldosterone-renin ratio. ( Ashby, MJ; Brown, MJ; Hood, SJ; Taylor, KP, 2007) |
| "Aldosterone antagonism has BP-independent effects on arterial stiffness." | 2.71 | Aldosterone-to-renin ratio, arterial stiffness, and the response to aldosterone antagonism in essential hypertension. ( Feely, J; Mahmud, A, 2005) |
| " Bendrofluazide appears to be an ineffective hypotensive agent at the standard dosage in the initial post-stroke period." | 2.71 | Bendrofluazide fails to reduce elevated blood pressure levels in the immediate post-stroke period. ( Eames, PJ; Panerai, RB; Potter, JF; Robinson, TG, 2005) |
| "Hypertension is associated with cognitive impairment in older adults." | 2.71 | Differential cognitive outcomes in the Hypertensive Old People in Edinburgh study. ( Starr, JM; Whalley, LJ, 2005) |
| "Hypertension is associated with impaired cognition, but it is unclear whether this impairment is reversible." | 2.68 | The effects of antihypertensive treatment on cognitive function: results from the HOPE study. ( Deary, IJ; Starr, JM; Whalley, LJ, 1996) |
| "Bendroflumethiazide was accompanied by minor but significant elevations in fasting plasma glucose and serum C-peptide." | 2.67 | Enalapril versus bendroflumethiazide in type 2 diabetes complicated by hypertension. ( Dollerup, J; Knudsen, RE; Mogensen, CE; Nielsen, S; Schmitz, A, 1994) |
| "Hypertension is a major risk factor for stroke and heart disease in the elderly." | 2.67 | A double-blind trial of captopril or bendrofluazide in newly diagnosed senile hypertension. ( Hadley, L; Inch, S; Starr, JM; Whalley, LJ; White, A, 1994) |
| "Captopril is a suitable alternative to bendrofluazide as an antihypertensive drug for elderly people with regard to ECG detected cardiac complications." | 2.67 | Hypertensive Old People in Edinburgh (HOPE) Study: electrocardiographic changes after captopril or bendrofluazide treatment. ( Starr, JM; Whalley, LJ, 1993) |
| "Ketanserin treatment reduced the incidence of nightmares (p less than 0." | 2.67 | Serotonin antagonism reduces the adverse symptoms of beta blockade. ( Chandler, A; Gould, SE; Korlipara, K; Taylor, NA, 1990) |
| " However, variability of plasma potassium within the dose interval was not increased markedly, and 12 hourly dosing is probably satisfactory for both potassium chloride and spironolactone at the doses studied." | 2.67 | Adequacy of twice daily dosing with potassium chloride and spironolactone in thiazide treated hypertensive patients. ( Brawn, LA; Ramsay, LE; Toner, JM; Yeo, WW, 1991) |
| "When bendroflumethiazide was added the favourable effect of captopril on the blood lipids disappeared while the undesirable effect of metoprolol became more pronounced." | 2.67 | The effect of captopril and metoprolol as monotherapy or combined with bendroflumethiazide on blood lipids. ( Foss, OP; Jensen, EK, 1990) |
| " After at least 6 months of treatment, the mean daily dosage of indoramin was higher among patients who received indoramin alone (122 mg/day) than among those who received indoramin plus a diuretic (92 mg/day)." | 2.66 | Antihypertensive therapy with indoramin in the elderly. ( Allen, IE; Deitch, MW; Pascucci, VL, 1986) |
| "A randomised trial of the treatment of hypertension in 884 patients aged 60 to 79 years at the onset showed a reduction of 18/11 mm Hg in blood pressure over a mean follow up period of 4." | 2.66 | Randomised trial of treatment of hypertension in elderly patients in primary care. ( Coope, J; Warrender, TS, 1986) |
| "Treatment with propranolol in non-smoking men in the highest age and blood pressure categories would lead to a reduction in the number having strokes from three to one or two and might possibly reduce the number experiencing myocardial infarction from seven to four." | 2.66 | Stroke and coronary heart disease in mild hypertension: risk factors and the value of treatment. Medical Research Council Working Party. ( , 1988) |
| "The propranolol-treated smokers tended to be younger, taller, thinner, and wre more likely to be black." | 2.66 | Cigarette smoking interferes with treatment of hypertension. ( Freis, ED; Henderson, WG; Materson, BJ; Reda, D, 1988) |
| "3." | 2.66 | Changes in calcium metabolic indices during long-term treatment of patients with essential hypertension. ( Bergström, R; Hvarfner, A; Lithell, H; Ljunghall, S; Mörlin, C; Wide, L, 1988) |
| "The patients with complex arrhythmias were older (p less than 0." | 2.66 | Ventricular dysrhythmias in middle-aged hypertensive men treated either with a diuretic agent or a beta-blocker. ( Hardarson, T; Ragnarsson, J; Snorrason, SP, 1987) |
| "Bendroflumethiazide 5 mg was given to 17 patients with essential hypertension who had persistent mild to moderate hypertension despite treatment with nifedipine slow-release tablets 20 mg bid." | 2.66 | The effects of bendroflumethiazide added to nifedipine in patients with hypertension. ( Beevers, DG; Gill, JS; Zezulka, AV, 1987) |
| "Counts of ventricular extrasystoles were significantly higher (p = 0." | 2.65 | Ventricular extrasystoles during thiazide treatment: substudy of MRC mild hypertension trial. ( , 1983) |
| "Atenolol was withdrawn in those allocated to labetalol and minoxidil was given only to men." | 2.65 | The 'third drug' trial: a comparative study of anti-hypertensive agents added to treatment when blood pressure is uncontrolled by a beta-blocker plus thiazide diuretic. ( Latham, L; Lorimer, AR; McAreavey, D; McLaren, D; Ramsay, LE; Reid, JL; Robertson, JI; Robertson, MP; Weir, RJ, 1983) |
| "Atenolol was withdrawn in those allocated to labetalol, and minoxidil was given only to men." | 2.65 | "Third drug" trial: comparative study of antihypertensive agents added to treatment when blood pressure remains uncontrolled by a beta blocker plus thiazide diuretic. ( Latham, L; Lorimer, AR; McAreavey, D; McLaren, AD; Ramsey, LE; Reid, JL; Robertson, JI; Robertson, MP; Weir, RJ, 1984) |
| " 4 The results suggest that the duration of antihypertensive effect of methyldopa is long enough to permit twice daily dosing, but that single daily dosing cannot be recommended for most patients." | 2.65 | Duration of effect of single daily dose methyldopa therapy. ( Dollery, CT; Orozco-Gonzalez, M; Polak, G; Wright, JM, 1982) |
| "Prazosin appears to be a potent and appropriate third agent." | 2.64 | Evaluation of beta blockade bendrofluazide, and prazosin in severe hypertension. ( Barritt, DW; Heaton, ST; Marshall, AJ; Pocock, J, 1977) |
| " In the dosage used, hydrallazine affected only the diastolic blood pressure, and when added to either bendrofluazide or bendrofluazide plus atenolol it produced a further mean reduction in pressure of 6 mm Hg." | 2.64 | Contribution of atenolol, bendrofluazide, and hydrallazine to management of severe hypertension. ( Mitchell, JR; Wilcox, RG, 1977) |
| " The plasma half-life after 5 mg averaged 4." | 2.64 | Pharmacokinetics of bendroflumenthiazide in hypertensive patients. ( Beermann, B; Groschinsky-Grind, M; Lindström, B; Wikland, B, 1978) |
| "When reserpine was withdrawn from nine women they followed a modified protocol comparing bendrofluazide and potassium chloride with potassium chloride alone." | 2.64 | Mild hypertension: a clinical trial conducted in hospital general practice. ( Garrett, RT; Joesbury, HE; Phillips, CA; Smith, AJ; Wilkes, E, 1976) |
| "Propranolol treatment gave a sustained reduction of PRA." | 2.64 | Plasma renin activity and blood pressure during long term treatment with propranolol and diuretic. ( Hesse, B; Nielsen, I; Steiness, E, 1976) |
| "Hypertension is an important risk factor for adverse cardiovascular events including stroke, myocardial infarction, heart failure and renal failure." | 2.55 | Pharmacotherapy for hypertension in adults aged 18 to 59 years. ( Gueyffier, F; Musini, VM; Puil, L; Salzwedel, DM; Wright, JM, 2017) |
| "For chlorthalidone, there were four comparisons with other medications, and the summary RR was statistically significant for cardiovascular disease outcomes (RR = 0." | 2.55 | Should we switch from bendrofluazide to chlorthalidone as the initial treatment for hypertension? A review of the available medication. ( Arroll, B; Wallace, H, 2017) |
| " These complications may be mitigated with careful monitoring, dosage adjustment, and replacement of electrolyte losses." | 2.41 | Diuretic complications. ( Greenberg, A, 2000) |
| "Flecainide has been shown to reduce salt absorption in animal bowel." | 1.34 | Flecainide cardiotoxicity precipitated by electrolyte imbalance. Caution with thiazide diuretics. ( Khavandi, A; Walker, PR, 2007) |
| " If patients failed to respond adequately at this dosage level, prazosin (0." | 1.27 | Timolol/bendrofluazide combination ('Prestim') in the treatment of poorly controlled hypertensive patients in general practice. ( Douglas-Jones, AP, 1984) |
| "When nifedipine was given to patients already on bendrofluazide, there was an additional fall in blood pressure." | 1.27 | Nifedipine, sodium intake, diuretics, and sodium balance. ( Cappuccio, FP; MacGregor, GA; Markandu, ND; Pevahouse, JB, 1987) |
| " Initial dosage of 1 tablet b." | 1.27 | [Potassium-sparing effect of triamterene in a 3-component combination preparation for the therapy of hypertension]. ( Dittrich, H; Nagler, J, 1986) |
| "6%) patients who required a dosage reduction and 2 (0." | 1.26 | A multi-centre general practice study on the use of a timolol/bendrofluazide combination ('Prestim') in the management of hypertension: preliminary report. ( Head, AC; Langrick, AF, 1981) |
| "Amiloride was disproportionately potent in lowering serum bicarbonate, and the data do not suggest that these drugs elevate plasma potassium simply by correcting metabolic alkalosis." | 1.26 | Amiloride, spironolactone, and potassium chloride in thiazide-treated hypertensive patients. ( Fraser, R; Hettiarachchi, J; Morton, JJ; Ramsay, LE, 1980) |
| " In a complementary investigation, 14 patients who completed the 16-weeks' treatment were changed onto a regimen in which the drug dosage remained unchanged but was taken on a once-daily basis for a further 16 weeks to assess the efficacy of once-daily dosing and to monitor any further long-term changes in biochemistry." | 1.26 | A hospital out-patient study of timolol/bendrofluazide combination ('Prestim') in essential hypertension. ( Kubik, MM, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 202 (68.24) | 18.7374 |
| 1990's | 47 (15.88) | 18.2507 |
| 2000's | 33 (11.15) | 29.6817 |
| 2010's | 14 (4.73) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| McNally, RJ | 1 |
| Morselli, F | 1 |
| Farukh, B | 1 |
| Chowienczyk, PJ | 1 |
| Faconti, L | 1 |
| Musini, VM | 1 |
| Gueyffier, F | 1 |
| Puil, L | 1 |
| Salzwedel, DM | 1 |
| Wright, JM | 2 |
| Goodyear-Smith, F | 1 |
| Arroll, B | 1 |
| Wallace, H | 1 |
| Macfarlane, TV | 1 |
| Pigazzani, F | 1 |
| Flynn, RWV | 1 |
| MacDonald, TM | 5 |
| Ripley, DP | 1 |
| Negrou, K | 1 |
| Oliver, JJ | 1 |
| Worthy, G | 1 |
| Struthers, AD | 3 |
| Plein, S | 1 |
| Greenwood, JP | 1 |
| Whitehead, J | 1 |
| Cleary, F | 1 |
| Turner, A | 1 |
| Kobel, MC | 1 |
| Nielsen, TK | 1 |
| Graumann, O | 1 |
| Chong, SJ | 1 |
| Howard, KA | 1 |
| Knox, C | 1 |
| Mehlsen, J | 1 |
| Mackenzie, IS | 1 |
| McEniery, CM | 1 |
| Dhakam, Z | 1 |
| Brown, MJ | 4 |
| Cockcroft, JR | 1 |
| Wilkinson, IB | 1 |
| Poulter, NR | 3 |
| Dobson, JE | 1 |
| Sever, PS | 4 |
| Dahlöf, B | 2 |
| Wedel, H | 2 |
| Campbell, NR | 1 |
| Almuntaser, I | 1 |
| Mahmud, A | 4 |
| Brown, A | 1 |
| Murphy, R | 1 |
| King, G | 1 |
| Crean, P | 1 |
| Feely, J | 4 |
| Parthasarathy, HK | 2 |
| Alhashmi, K | 2 |
| McMahon, AD | 2 |
| McInnes, GT | 2 |
| Ford, I | 2 |
| Connell, JM | 2 |
| Rabbani, N | 1 |
| Adaikalakoteswari, A | 1 |
| Rossing, K | 1 |
| Rossing, P | 2 |
| Tarnow, L | 1 |
| Parving, HH | 2 |
| Thornalley, PJ | 1 |
| Gupta, AK | 1 |
| Nasothimiou, EG | 1 |
| Chang, CL | 1 |
| Hoorn, EJ | 1 |
| Walsh, SB | 1 |
| McCormick, JA | 1 |
| Fürstenberg, A | 1 |
| Yang, CL | 1 |
| Roeschel, T | 1 |
| Paliege, A | 1 |
| Howie, AJ | 1 |
| Conley, J | 1 |
| Bachmann, S | 1 |
| Unwin, RJ | 1 |
| Ellison, DH | 1 |
| Peterzan, MA | 1 |
| Hardy, R | 1 |
| Chaturvedi, N | 1 |
| Hughes, AD | 1 |
| Haenni, A | 3 |
| Reneland, R | 1 |
| Andersson, PE | 2 |
| Lind, L | 3 |
| Lithell, H | 4 |
| COHEN, BM | 1 |
| FELDMAN, LH | 1 |
| GALBRAITH, JM | 1 |
| GRIEBLE, HG | 4 |
| JOHNSTON, LC | 4 |
| FULLER, JB | 2 |
| HATTINGER, J | 1 |
| AHBEL, AS | 1 |
| BREITENBACH, B | 1 |
| SOLTH, K | 1 |
| CRANSTON, WI | 1 |
| JUEL-JENSEN, BE | 1 |
| SEMMENCE, AM | 1 |
| JONES, RP | 1 |
| FORBES, JA | 1 |
| MUTCH, LM | 1 |
| KUEHNS, K | 1 |
| KUEPMANN, M | 1 |
| MAGNUS, D | 1 |
| CUMMINGS, DE | 1 |
| GOODMAN, RM | 1 |
| STEIGMANN, F | 1 |
| SCHOENBERGER, JA | 2 |
| ORVIS, HH | 1 |
| EPSTEIN, JH | 1 |
| KESSLER, S | 1 |
| THOMAS, RE | 1 |
| TAMAGNA, IG | 1 |
| ROEDIGER, PM | 1 |
| ALDEN, J | 1 |
| BEARDWOOD, D | 1 |
| HUTCHISON, JC | 3 |
| SIEGEL, I | 1 |
| GOSFIELD, E | 1 |
| GILLENWATER, J | 1 |
| REID, WJ | 1 |
| KING, JC | 1 |
| Girvin, BG | 1 |
| Johnston, GD | 7 |
| Michael, AB | 1 |
| Wallis, P | 1 |
| TELFEYAN, SA | 1 |
| Eames, PJ | 1 |
| Robinson, TG | 1 |
| Panerai, RB | 1 |
| Potter, JF | 1 |
| Starr, JM | 4 |
| Whalley, LJ | 4 |
| Schrader, J | 1 |
| Kulschewski, A | 1 |
| Hobbs, FR | 1 |
| Khan, T | 1 |
| Collins, B | 1 |
| Mahgoub, M | 1 |
| Hall, M | 1 |
| Füessl, HS | 1 |
| Rasmussen, S | 1 |
| Borrild, N | 1 |
| Vang Andersen, J | 1 |
| Vaikkakara, S | 1 |
| James, RA | 1 |
| Pearce, SH | 1 |
| Talks, SJ | 1 |
| Khavandi, A | 1 |
| Walker, PR | 1 |
| Spencer, CG | 2 |
| Felmeden, DC | 1 |
| Blann, AD | 2 |
| Lip, GY | 2 |
| Hood, SJ | 1 |
| Taylor, KP | 1 |
| Ashby, MJ | 1 |
| Rahn, KH | 1 |
| Mulatero, P | 1 |
| Milan, A | 1 |
| Veglio, F | 1 |
| McLaughlin, DM | 1 |
| Atkinson, AB | 5 |
| Ennis, CN | 4 |
| Browne, J | 1 |
| Hunter, SJ | 2 |
| Sheridan, B | 5 |
| Bell, PM | 5 |
| Pacy, PJ | 1 |
| Dodson, PM | 1 |
| Kubicki, AJ | 1 |
| Fletcher, RF | 1 |
| Taylor, KG | 2 |
| Coope, JR | 1 |
| Berglund, G | 7 |
| Andersson, O | 5 |
| Rodatz, KW | 1 |
| Hörder, MH | 1 |
| Elmfeldt, D | 2 |
| Wilhelmsen, L | 3 |
| Ellis, R | 1 |
| Wood, SJ | 1 |
| Freis, ED | 4 |
| Wheatley, D | 3 |
| Swales, JD | 8 |
| Bing, RF | 6 |
| Swart, S | 2 |
| Thurston, H | 8 |
| Lijnen, P | 4 |
| Staessen, J | 2 |
| Fagard, R | 4 |
| Amery, A | 6 |
| Cressman, MD | 1 |
| Gifford, RW | 1 |
| Verschueren, LJ | 1 |
| Peacock, K | 1 |
| Hodge, B | 1 |
| Mann, A | 1 |
| Gragnoli, G | 1 |
| Righi, GA | 1 |
| Turchetti, V | 1 |
| Mondillo, S | 1 |
| Kristodhullu, A | 1 |
| McAreavey, D | 2 |
| Ramsay, LE | 10 |
| Latham, L | 2 |
| Lorimer, AR | 4 |
| McLaren, D | 1 |
| Reid, JL | 4 |
| Robertson, JI | 2 |
| Robertson, MP | 2 |
| Weir, RJ | 4 |
| Degenring, FH | 1 |
| Ramsey, LE | 1 |
| McLaren, AD | 1 |
| Head, AC | 3 |
| Freestone, S | 2 |
| Andersen, GS | 3 |
| Gill, JS | 3 |
| Al-Hussary, N | 1 |
| Atkins, TW | 1 |
| Beevers, DG | 4 |
| Marchetta, F | 1 |
| Chiarini, C | 1 |
| Degli Esposti, E | 1 |
| Santoro, A | 1 |
| Sturani, A | 1 |
| Zuccalà, A | 1 |
| Zucchelli, P | 1 |
| Greenberg, G | 3 |
| Brennan, PJ | 4 |
| Miall, WE | 6 |
| Douglas-Jones, AP | 1 |
| Mörl, H | 1 |
| Al-Khader, AA | 1 |
| McGale, EH | 1 |
| Craven, D | 1 |
| Aber, GM | 1 |
| Wester, PO | 2 |
| Webster, J | 7 |
| Dollery, CT | 6 |
| Hensby, CN | 3 |
| Friedman, LA | 1 |
| Kristensen, BO | 1 |
| Brøns, M | 1 |
| Christensen, CK | 1 |
| Geday, E | 1 |
| Jacobsen, FK | 1 |
| Jensen, SN | 1 |
| Linde, NC | 1 |
| Russell, GI | 2 |
| Lewis, PJ | 1 |
| Crowley, KT | 1 |
| Heagerty, AM | 1 |
| Orozco-Gonzalez, M | 1 |
| Polak, G | 2 |
| Gomez, G | 2 |
| Langrick, AF | 1 |
| Hettiarachchi, J | 2 |
| Fraser, R | 2 |
| Morton, JJ | 2 |
| Solomon, LR | 1 |
| Dawes, PM | 3 |
| Silas, JH | 1 |
| Kubik, MM | 1 |
| Marshall, AJ | 3 |
| Kettle, MA | 1 |
| Barritt, DW | 3 |
| Winchester, JF | 1 |
| Kellett, RJ | 1 |
| Boddy, K | 1 |
| Boyle, P | 2 |
| Dargie, HJ | 1 |
| Mahaffey, ME | 1 |
| Ward, DM | 1 |
| Kennedy, AC | 1 |
| Rapeport, WG | 1 |
| Grimwood, VC | 1 |
| Korlipara, K | 3 |
| Grillage, MG | 1 |
| James, I | 1 |
| Anderton, JL | 1 |
| Selfridge, DI | 1 |
| Harper, R | 3 |
| Heaney, AP | 1 |
| Gormley, M | 1 |
| Hommel, E | 1 |
| Smidt, UM | 1 |
| Bulpitt, CJ | 3 |
| Fletcher, AE | 3 |
| Coope, J | 3 |
| Evans, JG | 2 |
| Lightowlers, S | 2 |
| O'Malley, K | 2 |
| Palmer, A | 2 |
| Potter, J | 2 |
| Sever, P | 3 |
| Nielsen, S | 1 |
| Schmitz, A | 1 |
| Knudsen, RE | 1 |
| Dollerup, J | 1 |
| Mogensen, CE | 1 |
| Inch, S | 1 |
| White, A | 1 |
| Hadley, L | 1 |
| Hosie, J | 1 |
| Nasar, MA | 1 |
| Belgrave, GP | 1 |
| Walters, EG | 1 |
| Berne, C | 1 |
| Fraser, A | 1 |
| Webb, DJ | 2 |
| Poulter, N | 2 |
| Chang, L | 1 |
| Bevan, EG | 1 |
| Pringle, SD | 1 |
| Waller, PC | 3 |
| Herrick, AL | 2 |
| Findlay, JG | 1 |
| Murray, GD | 1 |
| Carmichael, HA | 1 |
| Deary, IJ | 1 |
| Antonios, TF | 1 |
| Cappuccio, FP | 6 |
| Markandu, ND | 8 |
| Sagnella, GA | 3 |
| MacGregor, GA | 8 |
| Ritter, JM | 1 |
| Brett, SE | 1 |
| Woods, JD | 1 |
| Benjamin, N | 2 |
| Stratton, PD | 1 |
| Barrow, SE | 1 |
| Onion, CW | 1 |
| Dutton, CE | 1 |
| Walley, T | 1 |
| Turnbull, CJ | 1 |
| Dunne, WT | 1 |
| Buchan, IE | 1 |
| Fanestil, DD | 1 |
| Vaughn, DA | 1 |
| Ma, L | 1 |
| Hyde, RH | 1 |
| Printz, MP | 1 |
| Wilson, R | 1 |
| McDermott, BJ | 1 |
| Conroy, C | 1 |
| Crothers, E | 1 |
| Morgan, TO | 1 |
| Girvin, B | 1 |
| Isles, CG | 1 |
| Kitchin, NR | 1 |
| Andrews, PA | 1 |
| Sampson, SA | 1 |
| Wiggam, MI | 1 |
| Walmsley, A | 1 |
| Vanmolkot, FH | 1 |
| de Hoon, JN | 1 |
| van de Ven, LL | 1 |
| Van Bortel, LM | 1 |
| Greenberg, A | 1 |
| Lim, PO | 2 |
| Donnan, PT | 1 |
| Mayet, J | 1 |
| Ariff, B | 1 |
| Wasan, B | 1 |
| Chapman, N | 1 |
| Shahi, M | 2 |
| Foale, RA | 2 |
| Thom, SA | 1 |
| Tzemos, N | 1 |
| Ebbs, D | 1 |
| Uusimaa, P | 1 |
| Tokola, H | 1 |
| Ruskoaho, H | 1 |
| Vuolteenaho, O | 1 |
| Risteli, J | 1 |
| Ylitalo, A | 1 |
| Peuhkurinen, K | 1 |
| Bovet, P | 1 |
| Burnier, M | 1 |
| Madeleine, G | 1 |
| Waeber, B | 1 |
| Paccaud, F | 1 |
| Deary, AJ | 1 |
| Schumann, AL | 1 |
| Murfet, H | 1 |
| Haydock, SF | 1 |
| Foo, RS | 1 |
| Gurney, D | 1 |
| De Plaen, JF | 1 |
| Missotten, A | 2 |
| Wilcox, RG | 3 |
| Gudbrandsson, T | 1 |
| Hansson, L | 2 |
| Wilkinson, PR | 2 |
| Issler, H | 1 |
| Hesp, R | 2 |
| Raftery, EB | 2 |
| Pocock, J | 1 |
| Heaton, ST | 1 |
| Spira, M | 1 |
| Sivertsson, R | 1 |
| Deering, RB | 1 |
| Fox, AS | 1 |
| Ison, LJ | 1 |
| Mitchell, JR | 1 |
| Shelton, J | 1 |
| Roberts, CJ | 1 |
| Heaton, S | 1 |
| Braendli, B | 1 |
| Bucher, HJ | 1 |
| Nager, F | 1 |
| Truniger, B | 1 |
| Baber, NS | 2 |
| Jäättelä, A | 1 |
| Karatzas, NB | 1 |
| Papazachos, G | 1 |
| Clouva, P | 1 |
| Tsaknakis, T | 1 |
| Dawson, A | 1 |
| Johnson, BF | 1 |
| Smith, IK | 1 |
| Munro-Faure, AD | 1 |
| Horvath, JS | 1 |
| Caterson, RJ | 1 |
| Collett, P | 1 |
| Duggin, GG | 1 |
| Kelly, DH | 1 |
| Tiller, DJ | 1 |
| Zacharias, F | 1 |
| Lee, MR | 1 |
| Ball, SG | 1 |
| Thomas, TH | 1 |
| Morgan, DB | 1 |
| Robinson, IG | 1 |
| Allen, B | 1 |
| Agrawal, RL | 2 |
| Alliott, RJ | 1 |
| George, M | 1 |
| Trafford, JA | 1 |
| Jequier, PW | 1 |
| Lishman, JD | 1 |
| Turner, JR | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparisons Of Inflammatory Biomarkers And Cardiovascular Risk Scores Before And After Conversion To Full Dose Myfortic® Using Two Hour Neoral® Monitoring.[NCT02058875] | Phase 4 | 0 participants (Actual) | Interventional | 2014-02-28 | Withdrawn (stopped due to The study funder retracted their grant funding offer before contract signed.) | ||
| Effect of Combined Antihypertensive Therapy on Blood Pressure and Sexual Function in Patients With Essential Hypertension[NCT01238705] | Phase 4 | 280 participants (Anticipated) | Interventional | 2008-04-30 | Recruiting | ||
| Effect of Nebivolol on Blood Pressure in a Model of Hypertension Sensitive to Potentiation of Nitric Oxide Bioactivity[NCT01044693] | 20 participants (Actual) | Interventional | 2010-01-31 | Completed | |||
| Effects of Nebivolol on Microvascular Perfusion in the Skeletal Muscles During Exercise in Hypertensive Patients[NCT01501929] | Phase 4 | 32 participants (Actual) | Interventional | 2010-08-31 | Completed | ||
| Comparison of Single and Combination Diuretics in Low-Renin Hypertension[NCT02351973] | Phase 4 | 423 participants (Actual) | Interventional | 2009-11-30 | Active, not recruiting | ||
| Optimum Treatment for Drug-Resistant Hypertension[NCT02369081] | Phase 4 | 348 participants (Actual) | Interventional | 2009-05-31 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Change from baseline (8 pm) in heart rate at the time of maximal BP-lowering effect (NCT01044693)
Timeframe: 8 pm - 8 am
| Intervention | bpm (Mean) |
|---|---|
| Placebo Capsule | -3 |
| Nebivolol 5 mg | -6 |
| Metoprolol Tartrate 50 mg | -6 |
| Sildenafil 25 mg | 0 |
Nocturnal sodium excretion was defined as the ratio of urinary sodium to urinary creatinine. (NCT01044693)
Timeframe: 8 pm - 8 am
| Intervention | mEq/mg (Mean) |
|---|---|
| Placebo Capsule | 0.145 |
| Nebivolol 5 mg | 0.127 |
| Metoprolol Tartrate 50 mg | 0.139 |
| Sildenafil 25 mg | 0.125 |
Orthostatic tolerance was defined as the area under the curve of standing systolic blood pressure calculated by the trapezoidal rule (upright systolic blood pressure multiplied by standing time) during a 10-minute standing test (NCT01044693)
Timeframe: 10 min standing
| Intervention | mm Hg*min (Mean) |
|---|---|
| Placebo Capsule | 594 |
| Nebivolol 5 mg | 675 |
| Metoprolol Tartrate 50 mg | 696 |
| Sildenafil 25 mg | 575 |
Maximal change from baseline in systolic blood pressure, measured from 8 pm to 8 am, after a single dose of the intervention (NCT01044693)
Timeframe: 8 pm - 8 am
| Intervention | mm Hg (Mean) | |
|---|---|---|
| Baseline supine at 8 pm | Change in systolic BP | |
| Metoprolol Tartrate 50 mg | 157 | -7 |
| Nebivolol 5 mg | 162 | -24 |
| Placebo Capsule | 154 | 1 |
| Sildenafil 25 mg | 158 | -20 |
Endothelial cell (EC) was collected after a 20-guage angiocatheter was inserted into the contralateral forearm vein under sterile conditions. Three J-shaped vascular guidewires (St. Jude, St. Paul, MN) were advanced sequentially into the vein up to 10 cm. Endothelial cells were collected by gentle abrasion and placed into a dissociation buffer (0.5% bovine serum albumin, 2mM EDTA, and 100 ug/ml heparin in PBS). Endothelial cells were recovered from the tips of guide wires by repeated washing into collection tubes and subsequent centrifugation. EC were incubated with monoclonal antibodies against the polyclonal antibodies against NADPH oxidase p47 subunit. The intensity of staining was measured using fluorescence microscopy. (NCT01501929)
Timeframe: 12 weeks
| Intervention | Ratio human to HUVEC p47Phox expression (Mean) |
|---|---|
| Metoprolol | 0.47 |
| Nebivolol | 0.44 |
Microvascular perfusion of skeletal muscle were measured during handgrip at 20 cycle per minute after 12 weeks of metoprolol, and after 12 weeks of nebivolol (NCT01501929)
Timeframe: 12 weeks
| Intervention | video intensity units/ second (Median) |
|---|---|
| Metoprolol | 43.938 |
| Nebivolol | 74.584 |
12 reviews available for bendroflumethiazide and Hypertension
| Article | Year |
|---|---|
A review of the prescribing trend of thiazide-type and thiazide-like diuretics in hypertension: A UK perspective.
Topics: Antihypertensive Agents; Bendroflumethiazide; Blood Pressure; Drug Prescriptions; Drug Utilization; | 2019 |
Pharmacotherapy for hypertension in adults aged 18 to 59 years.
Topics: Adult; Antihypertensive Agents; Bendroflumethiazide; Blood Pressure; Cause of Death; Coronary Diseas | 2017 |
Should we switch from bendrofluazide to chlorthalidone as the initial treatment for hypertension? A review of the available medication.
Topics: Antihypertensive Agents; Bendroflumethiazide; Chlorthalidone; Drug Substitution; Humans; Hypertensio | 2017 |
The effect of indapamide vs. bendroflumethiazide for primary hypertension: a systematic review.
Topics: Bendroflumethiazide; Blood Pressure; Coronary Artery Disease; Diuretics; Humans; Hypertension; Indap | 2019 |
Meta-analysis of dose-response relationships for hydrochlorothiazide, chlorthalidone, and bendroflumethiazide on blood pressure, serum potassium, and urate.
Topics: Antihypertensive Agents; Bendroflumethiazide; Blood Pressure; Chlorthalidone; Dose-Response Relation | 2012 |
[Old or new antihypertensives--which are better?].
Topics: Adrenergic beta-Antagonists; Amlodipine; Angiotensin I; Angiotensin Receptor Antagonists; Angiotensi | 2005 |
The Hypertension in the Very Elderly Trial (HYVET). Rationale, methodology and comparison with previous trials.
Topics: Aged; Aged, 80 and over; Bendroflumethiazide; Delayed-Action Preparations; Diltiazem; Follow-Up Stud | 1994 |
Diuretic complications.
Topics: Acid-Base Equilibrium; Antihypertensive Agents; Bendroflumethiazide; Cardiovascular Diseases; Diuret | 2000 |
Beta-blockers vs. thiazides in the treatment of hypertension: a review of the experience of the large national trials.
Topics: Adrenergic beta-Antagonists; Bendroflumethiazide; Clinical Trials as Topic; Coronary Disease; Diuret | 1990 |
Calcium antagonists: use in hypertension evaluation of calcium antagonists in combination with diuretics.
Topics: Bendroflumethiazide; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Diuretics; | 1988 |
Ethnics differences in the reactions to drugs and xenobiotics. Antihypertensive agents.
Topics: Antihypertensive Agents; Bendroflumethiazide; Black People; Clinical Trials as Topic; Diuresis; Diur | 1986 |
Diuretic therapy.
Topics: Bendroflumethiazide; Diuretics; Edema; Furosemide; Humans; Hypertension; Skin Diseases; Thiadiazines | 1972 |
172 trials available for bendroflumethiazide and Hypertension
| Article | Year |
|---|---|
Aortic remodelling following the treatment and regression of hypertensive left ventricular hypertrophy: a cardiovascular magnetic resonance study.
Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Aorta, Th | 2015 |
Comparison of the effects of antihypertensive agents on central blood pressure and arterial stiffness in isolated systolic hypertension.
Topics: Administration, Oral; Aged; Analysis of Variance; Antihypertensive Agents; Arteries; Atenolol; Bendr | 2009 |
Baseline heart rate, antihypertensive treatment, and prevention of cardiovascular outcomes in ASCOT (Anglo-Scandinavian Cardiac Outcomes Trial).
Topics: Aged; Amlodipine; Antihypertensive Agents; Atenolol; Bendroflumethiazide; Coronary Disease; Europe; | 2009 |
Does the ratio of serum aldosterone to plasma renin activity predict the efficacy of diuretics in hypertension? Results of RENALDO.
Topics: Aldosterone; Bendroflumethiazide; Blood Pressure; Cross-Over Studies; Diuretics; Drug Therapy, Combi | 2010 |
Effect of Irbesartan treatment on plasma and urinary markers of protein damage in patients with type 2 diabetes and microalbuminuria.
Topics: Albuminuria; Amino Acids; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Bendrofl | 2012 |
Baseline predictors of resistant hypertension in the Anglo-Scandinavian Cardiac Outcome Trial (ASCOT): a risk score to identify those at high-risk.
Topics: Aged; Algorithms; Amlodipine; Antihypertensive Agents; Atenolol; Bendroflumethiazide; Diuretics; Dru | 2011 |
Skeletal muscle magnesium content is correlated with plasma glucose concentration in patients with essential hypertension treated with lisinopril or bendrofluazide.
Topics: Antihypertensive Agents; Bendroflumethiazide; Biopsy; Blood Glucose; Data Interpretation, Statistica | 2002 |
Comparison of the effects of a 7-day period of non-compliance on blood pressure control using three different antihypertensive agents.
Topics: Antihypertensive Agents; Bendroflumethiazide; Blood Pressure; Calcium Channel Blockers; Enalapril; H | 2004 |
Aldosterone-to-renin ratio, arterial stiffness, and the response to aldosterone antagonism in essential hypertension.
Topics: Aldosterone; Arteries; Bendroflumethiazide; Blood Flow Velocity; Blood Pressure; Compliance; Cross-O | 2005 |
Bendrofluazide fails to reduce elevated blood pressure levels in the immediate post-stroke period.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Bendroflumethiazide; Blood Pressure; Female; Human | 2005 |
Differential cognitive outcomes in the Hypertensive Old People in Edinburgh study.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Bendroflumethiazide; Blood Pressure; Captopril; Co | 2005 |
Doxazosin versus bendrofluazide: a comparison of the metabolic effects in British South Asians with hypertension.
Topics: Adolescent; Adrenergic alpha-Antagonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; A | 2005 |
Efficacy and safety of 24 weeks of therapy with bendroflumethiazide 1.25 mg/day or 2.5 mg/day and potassium chloride compared with enalapril 10 mg/day and amlodipine 5 mg/day in patients with mild to moderate primary hypertension : a multicentre, randomis
Topics: Adult; Aged; Amlodipine; Bendroflumethiazide; Enalapril; Female; Humans; Hypertension; Male; Middle | 2006 |
Low-dose quadruple antihypertensive combination: more efficacious than individual agents--a preliminary report.
Topics: Adrenergic beta-Antagonists; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive | 2007 |
Does the aldosterone:renin ratio predict the efficacy of spironolactone over bendroflumethiazide in hypertension? A clinical trial protocol for RENALDO (RENin-ALDOsterone) study.
Topics: Aldosterone; Bendroflumethiazide; Cross-Over Studies; Double-Blind Method; Humans; Hypertension; Ren | 2007 |
Effects of "newer" and "older" antihypertensive drugs on hemorrheological, platelet, and endothelial factors. A substudy of the Anglo-Scandinavian Cardiac Outcomes Trial.
Topics: Adrenergic beta-Antagonists; Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihyperte | 2007 |
The spironolactone, amiloride, losartan, and thiazide (SALT) double-blind crossover trial in patients with low-renin hypertension and elevated aldosterone-renin ratio.
Topics: Aged; Aldosterone; Amiloride; Bendroflumethiazide; Cross-Over Studies; Double-Blind Method; Female; | 2007 |
Comparison of effects of combined ACE inhibitor and low-dose thiazide diuretic with ACE inhibitor alone on insulin action in patients with hypertension and Type 2 diabetes: a double-blind crossover study.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Bendroflumethiazide; Capto | 2008 |
Hypertension in the over-60s.
Topics: Age Factors; Aged; Atenolol; Bendroflumethiazide; Humans; Hypertension; Middle Aged; Propanolamines | 1980 |
beta-blockers or diuretics in hypertension? A six year follow-up of blood pressure and metabolic side effects.
Topics: Adrenergic beta-Antagonists; Bendroflumethiazide; Blood Glucose; Blood Pressure; Clinical Trials as | 1981 |
Adverse reactions to bendrofluazide and propranolol for the treatment of mild hypertension. Report of Medical Research Council Working Party on Mild to Moderate Hypertension.
Topics: Adult; Bendroflumethiazide; Clinical Trials as Topic; Double-Blind Method; Erectile Dysfunction; Fem | 1981 |
Incidence and importance of metabolic side-effects during antihypertensive therapy.
Topics: Adrenergic beta-Antagonists; Bendroflumethiazide; Blood Glucose; Cholesterol; Clinical Trials as Top | 1983 |
Veterans Administration cooperative study on nadolol as monotherapy and in combination with a diuretic.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Bendroflumethiazide; Clinical Trials as Topic; Diure | 1984 |
Psychological stress and cardiovascular diseases.
Topics: Anti-Anxiety Agents; Bendroflumethiazide; Cardiovascular Diseases; Clinical Trials as Topic; Cloraze | 1984 |
Ventricular extrasystoles during thiazide treatment: substudy of MRC mild hypertension trial.
Topics: Adult; Bendroflumethiazide; Cardiac Complexes, Premature; Female; Humans; Hypertension; Male; Middle | 1983 |
Effect of bendrofluazide on the renin-angiotensin-aldosterone system and prostaglandins in captopril-resistant hypertensive patients.
Topics: Bendroflumethiazide; Captopril; Clinical Trials as Topic; Dinoprost; Dinoprostone; Double-Blind Meth | 1983 |
Controversies in hypertension: mild hypertension, isolated systolic hypertension, and the choice of a step one drug.
Topics: Adult; Aged; Antihypertensive Agents; Bendroflumethiazide; Blood Pressure; Clinical Trials as Topic; | 1983 |
Double-blind comparison between propranolol and bendroflumethiazide in captopril-treated resistant hypertensive patients.
Topics: Bendroflumethiazide; Body Weight; Captopril; Clinical Trials as Topic; Double-Blind Method; Drug Res | 1983 |
Prestim in the management of mild to moderate essential hypertension in general practice.
Topics: Adult; Aged; Bendroflumethiazide; Clinical Trials as Topic; Drug Combinations; Female; Humans; Hyper | 1983 |
Efficacy of nadolol alone and combined with bendroflumethiazide and hydralazine for systemic hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Bendroflumethiazide; Blood Pressure; Clinical Trials as Topic; | 1983 |
Hypertension: psychological aspects and diagnostic impact in a clinical trial.
Topics: Adult; Bendroflumethiazide; Blood Pressure; Clinical Trials as Topic; Female; Follow-Up Studies; Hum | 1984 |
Hydrochlorothiazide and bendroflumethiazide in low doses--a comparative trial.
Topics: Adult; Aged; Bendroflumethiazide; Blood Glucose; Blood Pressure; Clinical Trials as Topic; Double-Bl | 1984 |
[Evaluation of the antihypertensive effect and tolerability of nadolol administered alone or in association with bendroflumethiazide].
Topics: Adolescent; Adult; Aged; Bendroflumethiazide; Clinical Trials as Topic; Drug Evaluation; Drug Therap | 1984 |
The 'third drug' trial: a comparative study of anti-hypertensive agents added to treatment when blood pressure is uncontrolled by a beta-blocker plus thiazide diuretic.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Atenolol; Bendroflumethiazide; Blood Pressure; Cli | 1983 |
"Third drug" trial: comparative study of antihypertensive agents added to treatment when blood pressure remains uncontrolled by a beta blocker plus thiazide diuretic.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Atenolol; Bendroflumethiazide; Blood Pressure; Cli | 1984 |
Antihypertensive treatment in elderly patients in general practice (preliminary results).
Topics: Aged; Antihypertensive Agents; Atenolol; Bendroflumethiazide; Blood Pressure; Female; Humans; Hypert | 1983 |
[Combination therapy of hypertension. Results of a study with Docidrazin].
Topics: Bendroflumethiazide; Blood Pressure; Clinical Trials as Topic; Drug Combinations; Female; Humans; Hy | 1982 |
Urinary zinc excretion during treatment with different diuretics.
Topics: Adult; Aged; Bendroflumethiazide; Bumetanide; Chlorthalidone; Clinical Trials as Topic; Diuretics; F | 1980 |
Antihypertensive action of bendroflumethiazide: increased prostacyclin production?
Topics: Adult; Aged; Bendroflumethiazide; Blood Pressure; Electrolytes; Epoprostenol; Female; Humans; Hypert | 1980 |
Labetalol in mild and moderate hypertension. A report from the General Practitioner Research Group.
Topics: Adult; Aged; Bendroflumethiazide; Clinical Trials as Topic; Double-Blind Method; Ethanolamines; Fema | 1980 |
Circulating prostacyclin concentrations may be increased by bendrofluazide in patients with essential hypertension.
Topics: Bendroflumethiazide; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Epoprostenol; Hu | 1980 |
Antihypertensive effect of atenolol (100 mg once a day) and methyldopa (250 mg thrice a day). A double-blind cross-over multicentre study.
Topics: Adult; Aged; Atenolol; Bendroflumethiazide; Clinical Trials as Topic; Dose-Response Relationship, Dr | 1981 |
Indapamide and bendrofluazide: a comparison in the management of essential hypertension.
Topics: Adult; Bendroflumethiazide; Blood Pressure; Body Weight; Diuretics; Electrolytes; Female; Humans; Hy | 1981 |
Duration of effect of single daily dose methyldopa therapy.
Topics: Adult; Bendroflumethiazide; Blood Pressure; Double-Blind Method; Drug Administration Schedule; Heart | 1982 |
Treatment of essential hypertension with a combination of propranolol and bendrofluazide.
Topics: Adult; Bendroflumethiazide; Blood Pressure; Double-Blind Method; Drug Combinations; Drug Therapy, Co | 1980 |
Evaluation of indoramin added to oxprenolol and bendrofluazide as a third agent in severe hypertension.
Topics: Bendroflumethiazide; Blood Pressure; Drug Therapy, Combination; Female; Heart Rate; Humans; Hyperten | 1980 |
Metolazone and bendroflumethiazide in hypertension: physiologic and metabolic observations.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Bendroflumethiazide; Blood Pressure; Diuretics; Fe | 1980 |
The effect of tenidap on the anti-hypertensive efficacy of thiazide diuretics in patients treated for mild to moderate hypertension.
Topics: Adult; Aged; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Bendroflumethiazide; Diu | 1995 |
A comparison of the effects of low- and conventional-dose thiazide diuretic on insulin action in hypertensive patients with NIDDM.
Topics: Adult; Antihypertensive Agents; Bendroflumethiazide; Blood Glucose; Cross-Over Studies; Diabetes Mel | 1995 |
Angiotensin-converting enzyme inhibition in diabetic nephropathy: ten years' experience.
Topics: Adult; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Bendroflumethiazide; Blood Pressure; C | 1995 |
The Hypertension in the Very Elderly Trial (HYVET). Rationale, methodology and comparison with previous trials.
Topics: Aged; Aged, 80 and over; Bendroflumethiazide; Delayed-Action Preparations; Diltiazem; Follow-Up Stud | 1994 |
Effects of low dose versus conventional dose thiazide diuretic on insulin action in essential hypertension.
Topics: Bendroflumethiazide; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Female; | 1994 |
Enalapril versus bendroflumethiazide in type 2 diabetes complicated by hypertension.
Topics: Adult; Aged; Bendroflumethiazide; Diabetes Mellitus, Type 2; Double-Blind Method; Enalapril; Female; | 1994 |
A double-blind trial of captopril or bendrofluazide in newly diagnosed senile hypertension.
Topics: Aged; Bendroflumethiazide; Blood Cell Count; Blood Pressure; Captopril; Double-Blind Method; Female; | 1994 |
A comparative study of long acting diltiazem (Tildiem LA) with sustained release nifedipine (nifedipine SR) and bendrofluazide in the treatment of mild to moderate hypertension.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Bendroflumethiazide; Blood Pressure; Delaye | 1994 |
Electrolyte changes and metabolic effects of lisinopril/bendrofluazide treatment. Results from a randomized, double-blind study with parallel groups.
Topics: Bendroflumethiazide; Blood Glucose; Double-Blind Method; Electrolytes; Female; Glucose Tolerance Tes | 1994 |
The Hypertension in the Very Elderly Trial (HYVET).
Topics: Aged; Aged, 80 and over; Bendroflumethiazide; Cerebrovascular Disorders; Humans; Hypertension; Lisin | 1994 |
Hypertensive Old People in Edinburgh (HOPE) Study: electrocardiographic changes after captopril or bendrofluazide treatment.
Topics: Aged; Aged, 80 and over; Bendroflumethiazide; Captopril; Dose-Response Relationship, Drug; Double-Bl | 1993 |
Effects of atenolol withdrawal in patients on triple antihypertensive therapy.
Topics: Adult; Aged; Atenolol; Bendroflumethiazide; Captopril; Double-Blind Method; Drug Therapy, Combinatio | 1993 |
The effects of antihypertensive treatment on cognitive function: results from the HOPE study.
Topics: Aged; Antihypertensive Agents; Bendroflumethiazide; Cognition; Diuretics; Double-Blind Method; Femal | 1996 |
A diuretic is more effective than a beta-blocker in hypertensive patients not controlled on amlodipine and lisinopril.
Topics: Adrenergic beta-Antagonists; Adult; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypert | 1996 |
Prostacyclin biosynthesis in essential hypertension before and during treatment.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Amlodipine; Antihypertensive Agents; Bendroflumethiazide; | 1996 |
The blood pressure response to antihypertensive treatment with lisinopril or bendrofluazide is related to the calcium and magnesium contents in skeletal muscle.
Topics: Analysis of Variance; Antihypertensive Agents; Bendroflumethiazide; Biopsy; Blood Pressure; Calcium; | 1996 |
A low dose atenolol/bendrofluazide combination in patients with mild to moderate hypertension.
Topics: Adult; Antihypertensive Agents; Atenolol; Bendroflumethiazide; Dose-Response Relationship, Drug; Dou | 1997 |
Effects of combination therapy with an angiotensin converting enzyme inhibitor and thiazide diuretic on insulin action in essential hypertension.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Bendroflumethiazide; Blood Pressu | 1998 |
A randomized comparison of a conventional dose, a low dose and alternate-day dosing of bendrofluazide in hypertensive patients.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Bendroflumethiazide; Blood Pressure; Choles | 1998 |
A randomised double-blind study comparing nifedipine GITS 20 mg and bendrofluazide 2.5 mg administered once daily in mild-to-moderate hypertension.
Topics: Aged; Bendroflumethiazide; Blood Pressure; Calcium Channel Blockers; Diuretics; Double-Blind Method; | 1999 |
Low dose bendrofluazide (1.25 mg) effectively lowers blood pressure over 24 h: results of a randomized, double-blind, placebo-controlled crossover study.
Topics: Aged; Antihypertensive Agents; Bendroflumethiazide; Blood Pressure; Blood Pressure Monitoring, Ambul | 1999 |
Impact of antihypertensive treatment on quality of life: comparison between bisoprolol and bendrofluazide.
Topics: Adult; Aged; Antihypertensive Agents; Bendroflumethiazide; Bisoprolol; Blood Pressure; Cross-Over St | 1999 |
Does the Dundee Step Test predict outcome in treated hypertension? A sub-study protocol for the ASCOT trial. Anglo-Scandinavian Cardiac Outcome Trial.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Atenolol; Bendroflumethiazide; Blood Pressure; Diu | 2000 |
Nebivolol reverses endothelial dysfunction in essential hypertension: a randomized, double-blind, crossover study.
Topics: Acetylcholine; Adrenergic beta-Antagonists; Antihypertensive Agents; Atenolol; Bendroflumethiazide; | 2001 |
Nebivolol reverses endothelial dysfunction in essential hypertension: a randomized, double-blind, crossover study.
Topics: Acetylcholine; Adrenergic beta-Antagonists; Antihypertensive Agents; Atenolol; Bendroflumethiazide; | 2001 |
Nebivolol reverses endothelial dysfunction in essential hypertension: a randomized, double-blind, crossover study.
Topics: Acetylcholine; Adrenergic beta-Antagonists; Antihypertensive Agents; Atenolol; Bendroflumethiazide; | 2001 |
Nebivolol reverses endothelial dysfunction in essential hypertension: a randomized, double-blind, crossover study.
Topics: Acetylcholine; Adrenergic beta-Antagonists; Antihypertensive Agents; Atenolol; Bendroflumethiazide; | 2001 |
A comparison of selected antihypertensives and the use of conventional vs ambulatory blood pressure in the detection and treatment of hypertension.
Topics: Adult; Aged; Amlodipine; Analysis of Variance; Antihypertensive Agents; Bendroflumethiazide; Blood P | 2001 |
Double-blind, placebo-controlled crossover comparison of five classes of antihypertensive drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Amlodipine; Angiotensin-Converting | 2002 |
Double-blind, placebo-controlled crossover comparison of five classes of antihypertensive drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Amlodipine; Angiotensin-Converting | 2002 |
Double-blind, placebo-controlled crossover comparison of five classes of antihypertensive drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Amlodipine; Angiotensin-Converting | 2002 |
Double-blind, placebo-controlled crossover comparison of five classes of antihypertensive drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Amlodipine; Angiotensin-Converting | 2002 |
Von Willebrand factor, soluble P-selectin, and target organ damage in hypertension: a substudy of the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT).
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Atenolol; Bendroflumethiazide; Blood Pressure; Cro | 2002 |
Relative value of beta blockers and thiazides for initiating antihypertensive therapy. Beta blockers or thiazides in hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Bendroflumethiazide; Clinical Trials as Topic; Drug Ev | 1976 |
Randomised study of six beta-blockers and a thiazide diuretic in essential hypertension.
Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; Atenolol; Bendroflumethiazide; Clinical Trials as To | 1978 |
Combination therapy with saluretics and atenolol in essential hypertension. Effects on blood pressure, electrolytes and uric acid.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Bendroflumethiazide; Chlorthalidone; Diuretics; | 1979 |
Evaluation of beta blockade bendrofluazide, and prazosin in severe hypertension.
Topics: Adult; Aged; Atenolol; Bendroflumethiazide; Blood Pressure; Clinical Trials as Topic; Drug Evaluatio | 1977 |
Another trial in mild hypertension?
Topics: Bendroflumethiazide; Blood Pressure; Clinical Trials as Topic; Cost-Benefit Analysis; Humans; Hypert | 1977 |
A crossover comparison of a timolol/bendrofluazide combination and methyldopa in essential hypertension.
Topics: Adult; Aged; Bendroflumethiazide; Blood Pressure; Drug Combinations; Female; Heart Rate; Humans; Hyp | 1977 |
Randomised controlled trial of treatment for mild hypertension: design and pilot trial. Report of Medical Research Council Working Party on Mild to Moderate Hypertension.
Topics: Adult; Bendroflumethiazide; Clinical Trials as Topic; Economics, Medical; England; Female; Humans; H | 1977 |
The management vf essential hypertension with once daily administration of timolol maleate and bendrofluazide.
Topics: Adolescent; Adult; Aged; Bendroflumethiazide; Clinical Trials as Topic; Female; Humans; Hypertension | 1977 |
Contribution of atenolol, bendrofluazide, and hydrallazine to management of severe hypertension.
Topics: Bendroflumethiazide; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Femal | 1977 |
Combination hypotensive therapy with atenolol, bendrofluazide and hydrallazine.
Topics: Angiotensin II; Atenolol; Bendroflumethiazide; Blood Pressure; Clinical Trials as Topic; Double-Blin | 1977 |
The relative potency of amiloride and spironolactone in bendrofluazide-treated hypertensive patients [proceedings].
Topics: Amiloride; Bendroflumethiazide; Clinical Trials as Topic; Humans; Hypertension; Pyrazines; Spironola | 1978 |
Timolol and bendrofluazide in the management of hypertension in general practice.
Topics: Bendroflumethiazide; Blood Pressure; Clinical Trials as Topic; Drug Combinations; Humans; Hypertensi | 1978 |
Comparison of natriuretic, uricosuric, and antihypertensive properties of tienilic acid, bendrofluazide, and spironolactone.
Topics: Bendroflumethiazide; Blood Pressure; Clinical Trials as Topic; Diuretics; Double-Blind Method; Glyco | 1979 |
[Atenelol and bendrofluazide in the treatment of medium and severe hypertension (preliminary report)].
Topics: Atenolol; Bendroflumethiazide; Clinical Trials as Topic; Diastole; Female; Humans; Hypertension; Mal | 1978 |
Beta-adrenoceptor blocking drugs and diuretics in hypertension.
Topics: Bendroflumethiazide; Blood Pressure; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Hy | 1979 |
The fixed combination of propranolol and bendrofluazide in the treatment of hypertension.
Topics: Adult; Aged; Bendroflumethiazide; Capsules; Clinical Trials as Topic; Double-Blind Method; Drug Comb | 1979 |
Timolol and bendroflumethiazide in the treatment of hypertension.
Topics: Adult; Bendroflumethiazide; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Female | 1979 |
A comparison of the effects of labetalol, bendrofluazide and their combination in hypertension.
Topics: Adult; Bendroflumethiazide; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Comb | 1979 |
Labetalol and bendrofluazide: comparison of their antihypertensive effects.
Topics: Adult; Bendroflumethiazide; Clinical Trials as Topic; Double-Blind Method; Ethanolamines; Female; Hu | 1979 |
The treatment of hypertension with propranolol and bendrofluazide.
Topics: Adult; Aged; Bendroflumethiazide; Double-Blind Method; Drug Combinations; Humans; Hypertension; Midd | 1979 |
Pharmacokinetics of bendroflumenthiazide in hypertensive patients.
Topics: Adult; Aged; Bendroflumethiazide; Blood Pressure; Creatinine; Electrocardiography; Female; Heart Rat | 1978 |
[Controlled comparative trial of acebutolol and bendrofluazide alone or in association for the treatment of hypertension].
Topics: Acebutolol; Anxiety; Bendroflumethiazide; Clinical Trials as Topic; Drug Therapy, Combination; Femal | 1975 |
A new beta-adrenergic blocking drug in hypertension. A report from the General Practitioner Research Group.
Topics: Acebutolol; Bendroflumethiazide; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans | 1976 |
Mild hypertension: a clinical trial conducted in hospital general practice.
Topics: Adult; Aged; Bendroflumethiazide; Blood Pressure; Clinical Trials as Topic; Drug Combinations; Famil | 1976 |
Plasma renin concentration and the hypotensive effect of bendrofluazide and of atenolol.
Topics: Antihypertensive Agents; Atenolol; Bendroflumethiazide; Clinical Trials as Topic; Humans; Hypertensi | 1976 |
Medical Research Council's Treatment Trial for mild hypertension: an interim report.
Topics: Adult; Bendroflumethiazide; Clinical Trials as Topic; Female; Humans; Hypertension; Male; Middle Age | 1976 |
Controlled evaluation of bendroflumethiazide in the treatment of essential hypertension.
Topics: Adult; Aged; Bendroflumethiazide; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Hyperte | 1975 |
Antihypertensive effect and side-effects of bendroflumethiazide and propranolol.
Topics: Bendroflumethiazide; Blood Glucose; Blood Pressure; Heart Rate; Humans; Hypertension; Insulin; Male; | 1976 |
The problems of morbidity and therapy in borderline hypertension.
Topics: Adult; Bendroflumethiazide; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Persona | 1976 |
Plasma renin activity and blood pressure during long term treatment with propranolol and diuretic.
Topics: Adult; Bendroflumethiazide; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hypertension | 1976 |
Atenolol and bendrofluazide in hypertension.
Topics: Adult; Aged; Atenolol; Bendroflumethiazide; Body Weight; Clinical Trials as Topic; Drug Evaluation; | 1975 |
Quality of life on antihypertensive therapy: a double-blind trial comparing quality of life on pinacidil and nifedipine in combination with a thiazide diuretic. European Pinacidil Study Group.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Bendroflumethiazide; Blood Pressure; Data Interpre | 1992 |
Potassium supplementation versus bendrofluazide in mildly to moderately hypertensive Kenyans.
Topics: Adult; Bendroflumethiazide; Black People; Blood Pressure; Female; Humans; Hypertension; Kenya; Male; | 1991 |
A double-blind crossover study of the effect of concomitant diuretic therapy in hypertensive patients treated with amlodipine.
Topics: Adult; Amlodipine; Bendroflumethiazide; Blood Pressure; Calcium Channel Blockers; Double-Blind Metho | 1991 |
British MRC trial of treatment for mild hypertension--a more favorable interpretation.
Topics: Bendroflumethiazide; Cerebrovascular Disorders; Dose-Response Relationship, Drug; England; Humans; H | 1991 |
Serotonin antagonism reduces the adverse symptoms of beta blockade.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Bendroflumethiazide; Female; Humans; Hy | 1990 |
Primary prevention of sudden cardiovascular death in hypertensive patients. Mortality results from the MAPHY Study.
Topics: Adult; Arteriosclerosis; Bendroflumethiazide; Death, Sudden; Diuretics; Follow-Up Studies; Humans; H | 1991 |
The prevention of the maternal manifestations of pre-eclampsia by intensive antihypertensive treatment.
Topics: Adult; Atenolol; Bendroflumethiazide; Birth Weight; Drug Therapy, Combination; Embryonic and Fetal D | 1991 |
Adequacy of twice daily dosing with potassium chloride and spironolactone in thiazide treated hypertensive patients.
Topics: Adult; Aged; Bendroflumethiazide; Drug Administration Schedule; Drug Therapy, Combination; Female; H | 1991 |
[The optimal dose of bendroflumethiazide in hypertension. A randomized double-blind dose-response study].
Topics: Adult; Aged; Bendroflumethiazide; Dose-Response Relationship, Drug; Double-Blind Method; Drug Evalua | 1990 |
A comparison of the acute effects of cicletanine and bendrofluazide on urinary electrolytes and plasma potassium in essential hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Bendroflumethiazide; Blood Pressure; Creatinine; Diuretics; Do | 1990 |
Relation between dose of bendrofluazide, antihypertensive effect, and adverse biochemical effects.
Topics: Adult; Aged; Bendroflumethiazide; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Met | 1990 |
The effect of captopril and metoprolol as monotherapy or combined with bendroflumethiazide on blood lipids.
Topics: Adult; Aged; Bendroflumethiazide; Body Weight; Captopril; Cholesterol; Cholesterol, HDL; Drug Therap | 1990 |
Review: ventricular extrasystoles and thiazide treatment.
Topics: Bendroflumethiazide; Cardiac Complexes, Premature; Clinical Trials as Topic; Humans; Hypertension | 1985 |
Antihypertensive therapy with indoramin in the elderly.
Topics: Age Factors; Aged; Bendroflumethiazide; Blood Pressure; Clinical Trials as Topic; Drug Therapy, Comb | 1986 |
Calcium antagonists and sodium balance: effect of changes in sodium intake and of the addition of a thiazide diuretic on the blood pressure lowering effect of nifedipine.
Topics: Adult; Bendroflumethiazide; Blood Pressure; Double-Blind Method; Female; Humans; Hypertension; Male; | 1987 |
[Multicenter study of atenolol, combined with hydralazine and bendroflumethiazide in the treatment of essential, mild, and severe, arterial hypertension].
Topics: Adult; Aged; Atenolol; Bendroflumethiazide; Drug Therapy, Combination; Female; Humans; Hydralazine; | 1989 |
Pharmacokinetics of captopril and its effects on blood pressure during acute and chronic administration and in relation to food intake.
Topics: Adult; Aged; Bendroflumethiazide; Blood Pressure; Captopril; Eating; Female; Food; Half-Life; Heart | 1985 |
Treatment of hypertension with a fixed ratio combination of long-acting propranolol and bendrofluazide, and influence of age of the subject.
Topics: Adult; Age Factors; Aged; Aspartate Aminotransferases; Bendroflumethiazide; Delayed-Action Preparati | 1989 |
An assessment of Half-Inderal LA and Inderal LA in the treatment of hypertension in elderly subjects.
Topics: Aged; Bendroflumethiazide; Delayed-Action Preparations; Dose-Response Relationship, Drug; Double-Bli | 1989 |
Single doses of enalapril and atenolol in hypertensive patients treated with bendrofluazide.
Topics: Adult; Aged; Atenolol; Bendroflumethiazide; Blood Pressure; Double-Blind Method; Drug Therapy, Combi | 1987 |
Angiotensin converting enzyme inhibitors in the clinic: first-dose hypotension.
Topics: Atenolol; Bendroflumethiazide; Drug Therapy, Combination; Enalapril; Humans; Hypertension; Hypotensi | 1987 |
MRC trial of treatment of mild hypertension: principal results. Medical Research Council Working Party.
Topics: Adult; Bendroflumethiazide; Blood Pressure; Cerebrovascular Disorders; Clinical Trials as Topic; Cor | 1985 |
Coronary heart disease in the Medical Research Council trial of treatment of mild hypertension. Medical Research Council Working Party on Mild Hypertension.
Topics: Adult; Bendroflumethiazide; Clinical Trials as Topic; Coronary Disease; Death, Sudden; Female; Human | 1988 |
Comparison of enalapril and bendrofluazide for treatment of systemic hypertension.
Topics: Adolescent; Adult; Aged; Bendroflumethiazide; Clinical Trials as Topic; Double-Blind Method; Enalapr | 1987 |
Antihypertensive effect of single doses of enalapril in hypertensive patients treated with bendrofluazide.
Topics: Adult; Aged; Bendroflumethiazide; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Ena | 1987 |
Comparative trial of ketanserin or bendrofluazide as add-on therapy in hypertensive patients uncontrolled on a beta-blocker alone.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Bendroflumethiazide; Clinical Trials as Topic; Double-B | 1988 |
Randomised trial of treatment of hypertension in elderly patients in primary care.
Topics: Aged; Atenolol; Bendroflumethiazide; Blood Pressure; Cerebrovascular Disorders; Clinical Trials as T | 1986 |
The mild hypertension dilemma: results of the British MRC trial.
Topics: Adult; Antihypertensive Agents; Bendroflumethiazide; Cardiovascular Diseases; Cerebrovascular Disord | 1986 |
Stroke and coronary heart disease in mild hypertension: risk factors and the value of treatment. Medical Research Council Working Party.
Topics: Adult; Age Factors; Bendroflumethiazide; Blood Pressure; Cerebrovascular Disorders; Coronary Disease | 1988 |
Cigarette smoking interferes with treatment of hypertension.
Topics: Adult; Bendroflumethiazide; Black People; Double-Blind Method; Humans; Hydrochlorothiazide; Hyperten | 1988 |
Changes in calcium metabolic indices during long-term treatment of patients with essential hypertension.
Topics: Adult; Bendroflumethiazide; Blood Pressure; Calcium; Fatty Acids, Nonesterified; Female; Humans; Hyp | 1988 |
Calcium antagonists: use in hypertension evaluation of calcium antagonists in combination with diuretics.
Topics: Bendroflumethiazide; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Diuretics; | 1988 |
Verapamil and bendrofluazide in the treatment of hypertension: a controlled study of effectiveness alone and in combination.
Topics: Adult; Bendroflumethiazide; Blood Pressure; Body Weight; Clinical Trials as Topic; Double-Blind Meth | 1988 |
Ventricular dysrhythmias in middle-aged hypertensive men treated either with a diuretic agent or a beta-blocker.
Topics: Aged; Amiloride; Arrhythmias, Cardiac; Bendroflumethiazide; Clinical Trials as Topic; Drug Combinati | 1987 |
Mild hypertension--a therapeutic dilemma. The results of the MRC trial in Britain.
Topics: Adult; Bendroflumethiazide; Cerebrovascular Disorders; Clinical Trials as Topic; Female; Humans; Hyp | 1987 |
An update on the Medical Research Council Hypertension Trial.
Topics: Adult; Bendroflumethiazide; Blood Pressure; Cerebrovascular Disorders; Clinical Trials as Topic; Fem | 1987 |
Long-term follow-up of 500 patients with mild to moderate hypertension who had successfully completed a 3-month general practice study of a timolol-bendrofluazide combination ('Prestim').
Topics: Adult; Aged; Bendroflumethiazide; Body Weight; Clinical Trials as Topic; Drug Combinations; Female; | 1987 |
The effects of bendroflumethiazide added to nifedipine in patients with hypertension.
Topics: Adult; Bendroflumethiazide; Blood Glucose; Blood Pressure; Body Weight; Clinical Trials as Topic; De | 1987 |
Comparison of the antihypertensive efficacy and adverse reactions to two doses of bendrofluazide and hydrochlorothiazide and the effect of potassium supplementation on the hypotensive action of bendrofluazide: substudies of the Medical Research Council's
Topics: Adult; Bendroflumethiazide; Blood Pressure; Clinical Trials as Topic; Female; Humans; Hydrochlorothi | 1987 |
Comparative efficacy of captopril and atenolol in moderately severe essential hypertension.
Topics: Adult; Atenolol; Bendroflumethiazide; Captopril; Clinical Trials as Topic; Double-Blind Method; Drug | 1986 |
Further results of the MRC treatment trial for mild hypertension.
Topics: Bendroflumethiazide; Cerebrovascular Disorders; Clinical Trials as Topic; Coronary Disease; Death, S | 1987 |
Results of MRC (UK) trial of drug therapy for mild hypertension.
Topics: Adult; Bendroflumethiazide; Blood Pressure; Cerebrovascular Disorders; Clinical Trials as Topic; Fem | 1987 |
Double-blind comparison of Inderal LA (160 mg), Half-Inderal LA (80 mg), and Half-Inderal LA plus bendrofluazide (2.5 mg) in the treatment of elderly hypertensive patients.
Topics: Aged; Bendroflumethiazide; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; | 1987 |
A double-blind study of Inderex in the treatment of essential hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Bendroflumethiazide; Clinical Trials as Topic; Delayed-Action | 1987 |
The Medical Research Council Hypertension Trial: the smoking patient.
Topics: Adult; Bendroflumethiazide; Cerebrovascular Disorders; Coronary Disease; Female; Humans; Hypertensio | 1988 |
A double-blind study of the blood pressure lowering effect of a thiazide diuretic in hypertensive patients already on nifedipine and a beta-blocker.
Topics: Adult; Aged; Atenolol; Bendroflumethiazide; Blood Pressure; Double-Blind Method; Drug Therapy, Combi | 1987 |
Ethnics differences in the reactions to drugs and xenobiotics. Antihypertensive agents.
Topics: Antihypertensive Agents; Bendroflumethiazide; Black People; Clinical Trials as Topic; Diuresis; Diur | 1986 |
The Medical Research Council Trial.
Topics: Adult; Bendroflumethiazide; Blood Pressure; Clinical Trials as Topic; Female; Humans; Hypertension; | 1986 |
[Beta-blockers or thiazides for middle-aged and elderly patients with hypertension? A multicenter study in general practice].
Topics: Aged; Atenolol; Bendroflumethiazide; Clinical Trials as Topic; Humans; Hypertension; Middle Aged; Po | 1986 |
Low-dose antihypertensive treatment with a thiazide diuretic is not diabetogenic. A 10-year controlled trial with bendroflumethiazide.
Topics: Bendroflumethiazide; Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus; Follow-Up Studies; | 1986 |
The relationship between smoking and the response to anti-hypertensive treatment in mild hypertensives in the Medical Research Council's trial of treatment.
Topics: Adult; Bendroflumethiazide; Blood Pressure; Clinical Trials as Topic; Diastole; Female; Follow-Up St | 1987 |
The effects of bendroflumethiazide/potassium chloride versus hydrochlorothiazide/amiloride on blood pressure and serum electrolytes in patients with mild to moderate hypertension seen in general practice.
Topics: Adult; Aged; Amiloride; Bendroflumethiazide; Blood Pressure; Drug Therapy, Combination; Electrolytes | 1986 |
Comparison of nifedipine, prazosin and hydralazine added to treatment of hypertensive patients uncontrolled by thiazide diuretic plus beta-blocker.
Topics: Adult; Aged; Atenolol; Bendroflumethiazide; Blood Pressure; Drug Administration Schedule; Drug Thera | 1987 |
"Inderex" therapy in general practice.
Topics: Adult; Aged; Bendroflumethiazide; Blood Pressure; Clinical Trials as Topic; Drug Combinations; Famil | 1985 |
Effects of felodipine on rest and exercise heart rate and blood pressure in hypertensive patients.
Topics: Adult; Antihypertensive Agents; Bendroflumethiazide; Blood Pressure; Clinical Trials as Topic; Doubl | 1985 |
Fixed ratio combination of propranolol and bendrofluazide in the treatment of hypertension.
Topics: Adult; Aged; Bendroflumethiazide; Blood Pressure; Clinical Trials as Topic; Drug Combinations; Femal | 1985 |
[A 10-year follow-up of men with mild hypertension. Bendroflumethiazide and propranolol give equal effect in treatment of high blood pressure].
Topics: Bendroflumethiazide; Blood Glucose; Clinical Trials as Topic; Follow-Up Studies; Humans; Hypertensio | 1985 |
[Effective blood pressure reduction and few side-effects in treatment with captopril and diuretics].
Topics: Adult; Aged; Bendroflumethiazide; Captopril; Clinical Trials as Topic; Drug Therapy, Combination; Fe | 1985 |
[Controlled study of the antihypertensive efficacy of the combination of nadolol and bendroflumethiazide with respect to nadolol alone and placebo].
Topics: Adult; Antihypertensive Agents; Bendroflumethiazide; Clinical Trials as Topic; Double-Blind Method; | 1985 |
Atenolol versus bendroflumethiazide in middle-aged and elderly hypertensives.
Topics: Aged; Atenolol; Bendroflumethiazide; Blood Pressure; Clinical Trials as Topic; Drug Therapy, Combina | 1985 |
Third-line therapy. A cautionary note.
Topics: Atenolol; Bendroflumethiazide; Captopril; Chlorthalidone; Female; Humans; Hypertension; Male; Methyl | 1985 |
Adjuvant effect of bendrofluazide on propranolol in hypertension.
Topics: Adult; Bendroflumethiazide; Clinical Trials as Topic; Evaluation Studies as Topic; Female; Humans; H | 1972 |
Control of moderately raised blood pressure. Report of a co-operative randomized controlled trial.
Topics: Aged; Antihypertensive Agents; Bendroflumethiazide; Blood Pressure; Cardiovascular Diseases; Clinica | 1973 |
Practolol and bendrofluazide in treatment of hypertension.
Topics: Adult; Bendroflumethiazide; Blood Pressure; Body Weight; Clinical Trials as Topic; Drug Combinations | 1974 |
Controlled trial of hypotensive agents in hypertension in pregnancy.
Topics: Bendroflumethiazide; Birth Weight; Clinical Trials as Topic; Female; Fetal Death; Humans; Hypertensi | 1968 |
[Comparative assessment of the results of new antihypertensive drugs].
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Bendroflumethiazide; Female; Humans; Hypertension; | 1968 |
Metabolic and hypotensive effects of a new rauwolfia-thiazide combination.
Topics: Adult; Aged; Bendroflumethiazide; Benzothiadiazines; Blood Glucose; Blood Pressure; Blood Urea Nitro | 1969 |
115 other studies available for bendroflumethiazide and Hypertension
| Article | Year |
|---|---|
Guest Editorial: How valuable are systematic reviews for primary health care practitioners?
Topics: Bendroflumethiazide; Chlorthalidone; Humans; Hypertension; Primary Health Care | 2017 |
Bayesian sample sizes for exploratory clinical trials comparing multiple experimental treatments with a control.
Topics: Antihypertensive Agents; Bayes Theorem; Bendroflumethiazide; Bias; Blood Pressure; Dose-Response Rel | 2015 |
Acute renal failure and arterial hypertension due to subcapsular haematoma: is percutaneous drainage a feasible treatment?
Topics: Acute Kidney Injury; Aged; Antihypertensive Agents; Bendroflumethiazide; Blood Pressure; Drainage; F | 2016 |
Hypokalaemia and drinking green tea: a literature review and report of 2 cases.
Topics: Aged; Amlodipine; Antihypertensive Agents; Bendroflumethiazide; Drinking Behavior; Female; Humans; H | 2016 |
[Hypertension--does it matter how blood pressure is lowered?].
Topics: Amlodipine; Anticholesteremic Agents; Antihypertensive Agents; Atenolol; Atorvastatin; Bendroflumeth | 2008 |
Blood pressure control determines improvement in diastolic dysfunction in early hypertension.
Topics: Antihypertensive Agents; Bendroflumethiazide; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Fe | 2009 |
The calcineurin inhibitor tacrolimus activates the renal sodium chloride cotransporter to cause hypertension.
Topics: Analysis of Variance; Animals; Bendroflumethiazide; Calcineurin Inhibitors; Calcium; Cell Line; Chlo | 2011 |
Anti-hypertensive therapy with a fixed mixture of benzydroflumethiazide and Rauwolfia whole root.
Topics: Alkaloids; Antihypertensive Agents; Bendroflumethiazide; Chlorothiazide; Hypertension; Hypnotics and | 1960 |
A new antihypertensive preparation combining Rauwolfia, bendroflumethiazide and potassium.
Topics: Antihypertensive Agents; Bendroflumethiazide; Humans; Hypertension; North Carolina; Potassium; Rauwo | 1962 |
Bendroflumethiazide in hypertension and edematous states. Use in office practice.
Topics: Bendroflumethiazide; Chlorothiazide; Edema; Hypertension | 1962 |
Treatment of arterial hypertensive disease with diuretics. II. Effects on electrolytes and uric acid of bendroflumethiazide, potassium chloride, and spironolactone.
Topics: Bendroflumethiazide; Diuretics; Electrolytes; Humans; Hypertension; Potassium Chloride; Spironolacto | 1962 |
Treatment of arterial hypertensive disease with diuretics. I. Effects on blood pressure of bendroflumethiazide, potassium chloride, and spironolactone.
Topics: Bendroflumethiazide; Blood Pressure; Blood Pressure Determination; Diuretics; Humans; Hypertension; | 1962 |
[A contribution to the therapy of hypertension and postapoplectic sequelae].
Topics: Bendroflumethiazide; Cerebral Hemorrhage; Humans; Hypertension; Potassium; Reserpine | 1962 |
Combination Rauwolfia-diuretic preparations in the treatment of hypertension.
Topics: Bendroflumethiazide; Diuretics; Humans; Hypertension; Hypnotics and Sedatives; Rauwolfia | 1963 |
[Treatment of hypertension with Repicin].
Topics: Bendroflumethiazide; Chlorides; Humans; Hypertension; Hypotension; Potassium; Reserpine | 1962 |
EFFECTS OF ORAL DIURETICS ON RAISED ARTERIAL PRESSURE.
Topics: Arterial Pressure; Bendroflumethiazide; Benzothiadiazines; Blood; Blood Pressure Determination; Body | 1963 |
[POTASSIUM METABOLISM IN THE TREATMENT OF ESSENTIAL HYPERTENSION WITH THIAZIDE PREPARATIONS].
Topics: Bendroflumethiazide; Essential Hypertension; Humans; Hypertension; Metabolism; Potassium; Thiazides | 1963 |
BENDROFLUMETHIAZIDE IN THE TREATMENT OF CARDIAC EDEMA AND HYPERTENSION.
Topics: Ascorbic Acid; Bendroflumethiazide; Diuretics; Edema, Cardiac; Electrolytes; Feeding and Eating Diso | 1964 |
TREATMENT OF ARTERIAL HYPERTENSIVE DISEASE WITH DIURETICS. III. CHLORTHALIDONE ALONE AND IN COMBINATION WITH SPIRONOLACTONE.
Topics: Bendroflumethiazide; Cardiomegaly; Chlorides; Chlorthalidone; Coronary Disease; Creatine; Creatinine | 1964 |
ANTIHYPERTENSIVE THERAPY WITH ORAL DIURETICS.
Topics: Antihypertensive Agents; Bendroflumethiazide; Biomedical Research; Blood Chemical Analysis; Blood Pr | 1964 |
BENZOTHIADIAXINES AND DIABETES MELLITUS. II. COMPARISON OF HYPERGLYCEMIC EFFECTS OF BENDROFLUMETHIAZIDE AND CHLOROTHIAZIDE IN HYPERTENSIVE PATIENTS WITH DIABETES MELLITUS.
Topics: Amylases; Bendroflumethiazide; Blood; Blood Glucose; Chlorothiazide; Diabetes Mellitus; Drug Therapy | 1964 |
USE OF BENDROFLUMETHIAZIDE WITH POTASSIUM SUPPLEMENT IN TOXEMIA OF PREGNANCY.
Topics: Bendroflumethiazide; Blood; Blood Pressure; Drug Therapy; Eclampsia; Edema; Female; Fetal Death; Hum | 1965 |
SIX-MONTH DOUBLE-BLIND STUDY OF BENZOTHIADIAZINE DRUG EFFECTS ON HYPERTENSION AND SELECTED BLOOD CHEMISTRIES.
Topics: Bendroflumethiazide; Biomedical Research; Blood Chemical Analysis; Double-Blind Method; Drug Therapy | 1965 |
RAUWOLFIA-BENDROFLUMETHIAZIDE IN THE TREATMENT OF HYPERTENSION.
Topics: Bendroflumethiazide; Blood Pressure; Blood Pressure Determination; Chlorides; Drug Therapy; Geriatri | 1965 |
Clinical evaluation of bendroflumethiazide in hypertension and edematous states.
Topics: Bendroflumethiazide; Chlorothiazide; Edema; Edetic Acid; Hypertension | 1962 |
A case of hypertension and hyperkalaemia.
Topics: Antihypertensive Agents; Bendroflumethiazide; Diabetes Complications; Humans; Hyperkalemia; Hyperten | 2004 |
LOW-DOSAGE BENDROFLUMETHIAZIDE IN THE MANAGEMENT OF EDEMA AND HYPERTENSION.
Topics: Bendroflumethiazide; Disease Management; Edema; Hypertension; Toxicology | 1963 |
Does aldosterone-to-renin ratio predict the antihypertensive effect of the aldosterone antagonist spironolactone?
Topics: Aldosterone; Antihypertensive Agents; Bendroflumethiazide; Blood Pressure; Female; Humans; Hypertens | 2005 |
[Antihypertensive therapy: campaign of the giants].
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Atenolol; Bendroflumethiazide; Coronary Disease; D | 2005 |
A second corneal arcus?
Topics: Antihypertensive Agents; Arcus Senilis; Bendroflumethiazide; Female; Humans; Hypercalcemia; Hyperten | 2007 |
Flecainide cardiotoxicity precipitated by electrolyte imbalance. Caution with thiazide diuretics.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bendroflumethiazide; Diuretics; Drug Interactions; Ele | 2007 |
[Treating essential hypertension. Are beta blockers still first choice?].
Topics: Adrenergic beta-Antagonists; Amlodipine; Antihypertensive Agents; Atenolol; Bendroflumethiazide; Cor | 2007 |
Letter regarding article by Hood et al, "The Spironolactone, Amiloride, Losartan, and Thiazide (SALT) double-blind crossover trial in patients with low-renin hypertension and elevated aldosterone-renin ratio".
Topics: Aldosterone; Amiloride; Antihypertensive Agents; Bendroflumethiazide; Cross-Over Studies; Double-Bli | 2008 |
Treatment of arterial hypertensive disease with diuretics. V. Spironolactone, an aldosterone antagonist.
Topics: Adult; Bendroflumethiazide; Blood Pressure; Body Weight; Chlorthalidone; Female; Humans; Hyperaldost | 1967 |
Long-term treatment of hypertension with a preparation combining rauwolfia and bendroflumethiazide.
Topics: Adult; Aged; Bendroflumethiazide; Female; Humans; Hypertension; Male; Middle Aged; Phytotherapy; Pla | 1967 |
Comparison of the hypotensive and metabolic effects of bendrofluazide therapy and a high fibre, low fat, low sodium diet in diabetic subjects with mild hypertension.
Topics: Bendroflumethiazide; Blood Pressure; Diabetes Mellitus; Diet, Sodium-Restricted; Dietary Fats; Dieta | 1984 |
[Combined treatment of arterial hypertension. Comparison of a beta-blocker plus a saluretic combination with beta-blocker].
Topics: Adrenergic beta-Antagonists; Bendroflumethiazide; Drug Combinations; Female; Heart Rate; Humans; Hyp | 1983 |
The use of timolol/bendrofluazide (Prestim) in the treatment of hypertensive patients failing to respond to other antihypertensives.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Bendroflumethiazide; Diuretics; D | 1983 |
Diuretics, sodium intake, and renin in the management of hypertension.
Topics: Adult; Bendroflumethiazide; Blood Pressure; Body Weight; Diet, Sodium-Restricted; Diuretics; Female; | 1984 |
[Docidrazin. Long-term observation with a 3-component antihypertensive agent].
Topics: Adult; Aged; Antihypertensive Agents; Bendroflumethiazide; Drug Combinations; Female; Humans; Hydral | 1983 |
A multi-centre, general practice assessment of a timolol/bendrofluazide combination ('Prestim') in the treatment of mild to moderate hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Bendroflumethiazide; Blood Pressure; Drug Combinations; Female | 1984 |
Xipamide: no advantage over bendrofluazide in hypertension.
Topics: Bendroflumethiazide; Blood Pressure; Diuretics; Drug Synergism; Drug Therapy, Combination; Female; H | 1984 |
Possible role for insulin receptors in the mechanism of thiazide induced glucose tolerance.
Topics: Bendroflumethiazide; Blood Glucose; Diabetes Mellitus, Type 2; Diuretics; Drug Tolerance; Erythrocyt | 1984 |
[Treatment of essential arterial hypertension with nadolol and bendroflumethiazide].
Topics: Adult; Antihypertensive Agents; Bendroflumethiazide; Drug Evaluation; Drug Therapy, Combination; Fem | 1983 |
Effects of diuretic and beta-blocker therapy in the Medical Research Council Trial.
Topics: Adult; Bendroflumethiazide; Blood Pressure; Electrocardiography; England; Female; Humans; Hypertensi | 1984 |
Timolol/bendrofluazide combination ('Prestim') in the treatment of poorly controlled hypertensive patients in general practice.
Topics: Adult; Aged; Antihypertensive Agents; Bendroflumethiazide; Blood Pressure; Drug Combinations; Family | 1984 |
Dissociated renin-aldosterone response to acute sodium depletion in patients with a previous history of pregnancy-associated hypertension.
Topics: Adolescent; Adult; Aldosterone; Bendroflumethiazide; Blood Pressure; Body Weight; Female; Humans; Hy | 1980 |
Factors affecting the production of prostacyclin in man.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Bendroflumethiazide; Diabetic Retinopathy; Epoprostenol; Female | 1981 |
Plasma renin in long-term diuretic treatment of hypertension: effect of discontinuation and restarting therapy.
Topics: Bendroflumethiazide; Body Weight; Female; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged | 1982 |
The addition of prazosin to standard triple therapy in the treatment of severe hypertension.
Topics: Adult; Aged; Bendroflumethiazide; Blood Pressure; Drug Therapy, Combination; Electrocardiography; Fe | 1982 |
The effect of different antihypertensive therapies on plasma lipids.
Topics: Aged; Bendroflumethiazide; Cholesterol; Ethanolamines; Female; Humans; Hypertension; Labetalol; Lipo | 1982 |
A multi-centre general practice study on the use of a timolol/bendrofluazide combination ('Prestim') in the management of hypertension: preliminary report.
Topics: Adolescent; Adult; Aged; Aging; Bendroflumethiazide; Blood Pressure; Drug Combinations; Female; Huma | 1981 |
Amiloride, spironolactone, and potassium chloride in thiazide-treated hypertensive patients.
Topics: Adult; Aldosterone; Amiloride; Angiotensin II; Bendroflumethiazide; Bicarbonates; Blood Pressure; Di | 1980 |
Diuretic treatment of resistant hypertension.
Topics: Adult; Aged; Bendroflumethiazide; Body Weight; Cyclopenthiazide; Drug Resistance; Female; Furosemide | 1980 |
A hospital out-patient study of timolol/bendrofluazide combination ('Prestim') in essential hypertension.
Topics: Adolescent; Adult; Aged; Bendroflumethiazide; Drug Combinations; Female; Heart Rate; Humans; Hyperte | 1980 |
Low dose thiazide diuretic. Is not available for prescribing.
Topics: Bendroflumethiazide; Drug Costs; Drug Prescriptions; Humans; Hypertension | 1994 |
Low dose thiazide diuretic. May not lower blood pressure effectively.
Topics: Bendroflumethiazide; Blood Pressure; Drug Administration Schedule; Humans; Hypertension | 1994 |
Local clinical guidelines: description and evaluation of a participative method for their development and implementation.
Topics: Aged; Antihypertensive Agents; Bendroflumethiazide; Blood Pressure; Dose-Response Relationship, Drug | 1996 |
Thiazide diuretics normalize urinary calcium in spontaneously hypertensive male rats.
Topics: Animals; Bendroflumethiazide; Calcium; Chlorides; Diuretics; Hypertension; Ion Transport; Kidney Tub | 1997 |
Atenolol, bendrofluazide and their use in combination.
Topics: Antihypertensive Agents; Atenolol; Bendroflumethiazide; Drug Therapy, Combination; Humans; Hypertens | 1998 |
Topical non-steroidal drugs are systemically absorbed and may cause renal disease.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Bendroflumethiazide; Biopsy; Diuretics; Fenoprofen; Glomeru | 1999 |
Improvement in midwall myocardial shortening with regression of left ventricular hypertrophy.
Topics: Adult; Antihypertensive Agents; Bendroflumethiazide; Blood Pressure; Cardiac Output; Echocardiograph | 2000 |
Vasoactive peptides and procollagen propeptides in patients with hypertension in relation to cardiac hypertrophy and diastolic heart failure: design of the study and patient characteristics.
Topics: Amlodipine; Antihypertensive Agents; Atenolol; Atrial Natriuretic Factor; Bendroflumethiazide; Cardi | 2001 |
Monitoring one-year compliance to antihypertension medication in the Seychelles.
Topics: Adult; Antihypertensive Agents; Atenolol; Bendroflumethiazide; Cross-Sectional Studies; Drug Monitor | 2002 |
Total body and serum potassium during prolonged thiazide therapy for essential hypertension.
Topics: Bendroflumethiazide; Bicarbonates; Blood Pressure; Blood Pressure Determination; Humans; Hypertensio | 1975 |
Low renin hypertension. A distinct entity.
Topics: Adolescent; Adult; Aged; Bendroflumethiazide; Blood Pressure; Female; Humans; Hypertension; Male; Mi | 1976 |
Potassium supplementation of thiazide therapy.
Topics: Adult; Aged; Bendroflumethiazide; Female; Humans; Hypertension; Male; Middle Aged; Potassium; Potass | 1976 |
Salt intake and diuretic treatment of hypertension.
Topics: Adult; Bendroflumethiazide; Blood Pressure; Circadian Rhythm; Diet, Sodium-Restricted; Evaluation St | 1979 |
Primary hypertension refractory to triple drug treatment - a study on central and peripheral hemodynamics.
Topics: Bendroflumethiazide; Drug Therapy, Combination; Hemodynamics; Humans; Hydralazine; Hydrochlorothiazi | 1979 |
Tienilic acid in hypertension with hyperuricaemia.
Topics: Allopurinol; Bendroflumethiazide; Creatinine; Female; Glycolates; Gout; Humans; Hypertension; Male; | 1979 |
Hypertension and hyperkalaemia responding to bendrofluazide.
Topics: Adult; Aldosterone; Arginine Vasopressin; Bendroflumethiazide; Diet, Sodium-Restricted; Furosemide; | 1979 |
Labetalol and bendrofluazide.
Topics: Bendroflumethiazide; Diuretics; Drug Therapy, Combination; Ethanolamines; Humans; Hypertension; Labe | 1979 |
Effects on rat urinary kallikrein excretion of bumetanide, bendroflumethiazide and hydralazine.
Topics: Administration, Oral; Animals; Bendroflumethiazide; Bumetanide; Diuretics; Hydralazine; Hypertension | 1977 |
Factors influencing serum potassium in treated hypertension.
Topics: Adult; Aged; Bendroflumethiazide; Creatinine; Diuretics; Female; Humans; Hypertension; Hypokalemia; | 1977 |
Renin subgroups in essential hypertension: an analysis and critique.
Topics: Angiotensin II; Bendroflumethiazide; Humans; Hypertension; Middle Aged; Renin; Sodium | 1978 |
Influence of thiazides on thyroid parameters in man.
Topics: Adult; Bendroflumethiazide; Diuretics; Female; Humans; Hydrochlorothiazide; Hydroflumethiazide; Hype | 1978 |
Sympathetic nervous function and renin activity in hypertensives on long term drug treatment with propranolol, methyldopa or bendrofluazide.
Topics: Adult; Antihypertensive Agents; Bendroflumethiazide; Blood Pressure; Female; Humans; Hypertension; M | 1978 |
Plasma renin and angiotensin II measurement in hypertensive and normal subjects: correlation of basal and stimulated states.
Topics: Adult; Angiotensin II; Bendroflumethiazide; Diazoxide; Female; Humans; Hypertension; Male; Middle Ag | 1977 |
[Treatment of hypertension using propranolol combined with hydralazine and a thiazidine diuretic. 1st results].
Topics: Adult; Aged; Bendroflumethiazide; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertensi | 1975 |
[Saluretics or beta blocking agents in the treatment of hypertension?].
Topics: Bendroflumethiazide; Blood Glucose; Humans; Hypertension; Insulin; Male; Middle Aged; Potassium; Pro | 1976 |
The case for low dose diuretic therapy.
Topics: Bendroflumethiazide; Cyclopenthiazide; Diuretics; Dose-Response Relationship, Drug; Humans; Hyperten | 1991 |
Antihypertensive and adverse biochemical effects of bendrofluazide.
Topics: Adrenergic beta-Antagonists; Bendroflumethiazide; Humans; Hypertension | 1990 |
Regression of hypertensive left ventricular hypertrophy and left ventricular diastolic function.
Topics: Adult; Aged; Bendroflumethiazide; Blood Pressure; Captopril; Cardiomegaly; Diastole; Drug Administra | 1990 |
Antihypertensive and adverse biochemical effects of bendrofluazide.
Topics: Bendroflumethiazide; Humans; Hypertension; Potassium Chloride | 1990 |
Grinspan's syndrome: a drug-induced phenomenon?
Topics: Aged; Aged, 80 and over; Atenolol; Bendroflumethiazide; Chlorpropamide; Diabetes Mellitus, Type 2; D | 1990 |
Antihypertensive and adverse biochemical effects of bendrofluazide.
Topics: Antihypertensive Agents; Bendroflumethiazide; Cholesterol; Humans; Hypertension | 1990 |
Severe thiazide-induced hyponatraemia during treatment with enalapril.
Topics: Aged; Bendroflumethiazide; Drug Therapy, Combination; Enalapril; Female; Humans; Hypertension; Hypon | 1987 |
[Efficacy of the nadolol-bendroflumethiazide combination in the treatment of arterial hypertension].
Topics: Adrenergic beta-Antagonists; Aged; Bendroflumethiazide; Drug Combinations; Female; Humans; Hypertens | 1986 |
[Nadolol + bendroflumethiazide in a fixed combination and in sequential administration. Experimental research on antihypertensive efficacy and tolerability].
Topics: Adrenergic beta-Antagonists; Aged; Bendroflumethiazide; Drug Combinations; Drug Therapy, Combination | 1986 |
Does angiotensin-II protect against strokes?
Topics: Angiotensin II; Bendroflumethiazide; Cerebral Infarction; Cerebrovascular Circulation; Cerebrovascul | 1986 |
Strokes in mild hypertension: diastolic rules.
Topics: Bendroflumethiazide; Blood Pressure Determination; Cerebrovascular Disorders; Diastole; Humans; Hype | 1986 |
Diuretics and calcium antagonists in hypertension.
Topics: Bendroflumethiazide; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension | 1988 |
Changes in red cell sodium content and blood pressure levels with potassium supplementation in black hypertensive patients.
Topics: Bendroflumethiazide; Black People; Blood Pressure; Drug Therapy, Combination; Erythrocytes; Female; | 1988 |
Age and antihypertensive drugs (hydrochlorothiazide, bendroflumethiazide, nadolol and captopril).
Topics: Adult; Aged; Aging; Bendroflumethiazide; Black People; Blood Pressure; Captopril; Dose-Response Rela | 1988 |
Nifedipine, sodium intake, diuretics, and sodium balance.
Topics: Bendroflumethiazide; Blood Pressure; Drug Interactions; Drug Therapy, Combination; Female; Humans; H | 1987 |
An abnormal response of the adrenal cortex to insulin: glucose in essential hypertension.
Topics: Adrenal Cortex; Aldosterone; Bendroflumethiazide; Blood Pressure; Glucose; Humans; Hydrocortisone; H | 1986 |
[Study of tolerance to antihypertensive medication].
Topics: Antihypertensive Agents; Bendroflumethiazide; Drug Tolerance; Humans; Hypertension; Middle Aged; Pro | 1987 |
Does a diuretic cause a further fall in blood pressure in hypertensive patients already on nifedipine?
Topics: Adult; Aged; Bendroflumethiazide; Blood Pressure; Drug Evaluation; Drug Therapy, Combination; Female | 1986 |
Treating mild hypertension.
Topics: Bendroflumethiazide; Cerebrovascular Disorders; Coronary Disease; Female; Humans; Hypertension; Male | 1985 |
[Potassium-sparing effect of triamterene in a 3-component combination preparation for the therapy of hypertension].
Topics: Bendroflumethiazide; Blood Pressure; Bupranolol; Drug Combinations; Female; Heart Rate; Humans; Hype | 1986 |
Renal excretion of electrolytes in patients on long-term diuretic therapy for arterial hypertension and/or congestive heart failure.
Topics: Aged; Bendroflumethiazide; Diuretics; Electrolytes; Extracellular Space; Female; Furosemide; Heart F | 1985 |
Potassium and diuretic therapy.
Topics: Bendroflumethiazide; Diuresis; Humans; Hypertension; Potassium | 1972 |
Letter: Potassium supplements.
Topics: Bendroflumethiazide; Drug Therapy, Combination; Humans; Hyperkalemia; Hypertension; Potassium; Potas | 1974 |
Beta blockers in hypertension.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Bendroflumethiazide; Diuretics; Drug Therapy, | 1973 |
[Pharmacological studies on diuretics. 7. Diuretic activity and mechanism of action of a new thiazide diuretic, penfluzide].
Topics: Adenosine Triphosphatases; Alkalosis; Animals; Antihypertensive Agents; Bendroflumethiazide; Blood P | 1973 |
Blood lipids and the treatment of essential hypertension with methyldopa and bendrolfuazide.
Topics: Adult; Aged; Bendroflumethiazide; Drug Therapy, Combination; Female; Humans; Hypertension; Lipids; M | 1974 |
Thiazide-induced hypercalcemia in vitamin D-treated hypoparathyroidism.
Topics: Adult; Aged; Bendroflumethiazide; Calcium; Chlorothiazide; Edema; Female; Humans; Hypercalcemia; Hyp | 1972 |
Detection of hypertension in childhood.
Topics: Age Factors; Bendroflumethiazide; Child; Child, Preschool; Cholesterol; Guanethidine; Humans; Hypert | 1973 |
The effect of bendroflumethiazide on total, ultrafiltrable and ionized calcium in serum in normocalcaemic renal stone formers and in hyperparathyroidism.
Topics: Absorption; Administration, Oral; Adult; Aged; Bendroflumethiazide; Blood Proteins; Calcium; Creatin | 1973 |
[The antihypertensive effects of bendroflumethiazide, hydroflumethiazide, trichlormethiazide, chlorthalidone and furosemide].
Topics: Adult; Aged; Bendroflumethiazide; Chlorthalidone; Diuretics; Female; Furosemide; Humans; Hydroflumet | 1973 |
[Treatment of arterial hypertension by diuretic sulfamide-reserpine association. 20 cases].
Topics: Aged; Bendroflumethiazide; Drug Synergism; Humans; Hypertension; Reserpine | 1970 |
Clinical evaluation of Declinax in Nigerian hypertensives.
Topics: Adult; Aged; Amidines; Antihypertensive Agents; Bendroflumethiazide; Drug Synergism; Female; Humans; | 1970 |
Reversible hypercalcemia associated with prolonged thiazide administration to control hypertension.
Topics: Bendroflumethiazide; Blood Chemical Analysis; Humans; Hypercalcemia; Hyperparathyroidism, Secondary; | 1970 |
Essential hypertension and its treatment by the family physician. A study of sixty-one cases.
Topics: Aged; Bendroflumethiazide; Drug Synergism; Family Practice; Female; Humans; Hypertension; Male; Midd | 1970 |
Hypertension. I.
Topics: Adult; Bendroflumethiazide; Cerebrovascular Disorders; Coronary Disease; Diuretics; Female; Humans; | 1971 |