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bendroflumethiazide and Diabetes Mellitus, Type 2

bendroflumethiazide has been researched along with Diabetes Mellitus, Type 2 in 6 studies

Bendroflumethiazide: A thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)
bendroflumethiazide : A sulfonamide consisting of 7-sulfamoyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide in which the hydrogen at position 6 is substituted by a trifluoromethyl group and that at position 3 is substituted by a benzyl group.

Diabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.

Research Excerpts

ExcerptRelevanceReference
"Bendroflumethiazide was accompanied by minor but significant elevations in fasting plasma glucose and serum C-peptide."6.67Enalapril versus bendroflumethiazide in type 2 diabetes complicated by hypertension. ( Dollerup, J; Knudsen, RE; Mogensen, CE; Nielsen, S; Schmitz, A, 1994)
"We examined the effects on insulin sensitivity of captopril either alone or in combination with low-dose bendroflumethiazide (1."5.13Comparison of effects of combined ACE inhibitor and low-dose thiazide diuretic with ACE inhibitor alone on insulin action in patients with hypertension and Type 2 diabetes: a double-blind crossover study. ( Atkinson, AB; Bell, PM; Browne, J; Ennis, CN; Hunter, SJ; McLaughlin, DM; Sheridan, B, 2008)
"Treatment of patients with type 2 diabetes with Irbesartan decreased urinary excretion of MG-H1, G-H1 and 3-NT, which may result from decreased exposure to these AGEs."2.77Effect of Irbesartan treatment on plasma and urinary markers of protein damage in patients with type 2 diabetes and microalbuminuria. ( Adaikalakoteswari, A; Parving, HH; Rabbani, N; Rossing, K; Rossing, P; Tarnow, L; Thornalley, PJ, 2012)
"Bendroflumethiazide was accompanied by minor but significant elevations in fasting plasma glucose and serum C-peptide."2.67Enalapril versus bendroflumethiazide in type 2 diabetes complicated by hypertension. ( Dollerup, J; Knudsen, RE; Mogensen, CE; Nielsen, S; Schmitz, A, 1994)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's3 (50.00)18.2507
2000's1 (16.67)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rabbani, N1
Adaikalakoteswari, A1
Rossing, K1
Rossing, P1
Tarnow, L1
Parving, HH1
Thornalley, PJ1
McLaughlin, DM1
Atkinson, AB2
Ennis, CN2
Browne, J1
Hunter, SJ1
Sheridan, B2
Bell, PM2
Gill, JS1
Al-Hussary, N1
Atkins, TW1
Taylor, KG1
Beevers, DG1
Harper, R1
Heaney, AP1
Gormley, M1
Johnston, GD1
Nielsen, S1
Schmitz, A1
Knudsen, RE1
Dollerup, J1
Mogensen, CE1
Lamey, PJ1
Gibson, J1
Barclay, SC1
Miller, S1

Trials

4 trials available for bendroflumethiazide and Diabetes Mellitus, Type 2

ArticleYear
Effect of Irbesartan treatment on plasma and urinary markers of protein damage in patients with type 2 diabetes and microalbuminuria.
    Amino acids, 2012, Volume: 42, Issue:5

    Topics: Albuminuria; Amino Acids; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Bendrofl

2012
Comparison of effects of combined ACE inhibitor and low-dose thiazide diuretic with ACE inhibitor alone on insulin action in patients with hypertension and Type 2 diabetes: a double-blind crossover study.
    Diabetic medicine : a journal of the British Diabetic Association, 2008, Volume: 25, Issue:5

    Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Bendroflumethiazide; Capto

2008
A comparison of the effects of low- and conventional-dose thiazide diuretic on insulin action in hypertensive patients with NIDDM.
    Diabetologia, 1995, Volume: 38, Issue:7

    Topics: Adult; Antihypertensive Agents; Bendroflumethiazide; Blood Glucose; Cross-Over Studies; Diabetes Mel

1995
Enalapril versus bendroflumethiazide in type 2 diabetes complicated by hypertension.
    QJM : monthly journal of the Association of Physicians, 1994, Volume: 87, Issue:12

    Topics: Adult; Aged; Bendroflumethiazide; Diabetes Mellitus, Type 2; Double-Blind Method; Enalapril; Female;

1994

Other Studies

2 other studies available for bendroflumethiazide and Diabetes Mellitus, Type 2

ArticleYear
Possible role for insulin receptors in the mechanism of thiazide induced glucose tolerance.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1984, Volume: 2, Issue:3

    Topics: Bendroflumethiazide; Blood Glucose; Diabetes Mellitus, Type 2; Diuretics; Drug Tolerance; Erythrocyt

1984
Grinspan's syndrome: a drug-induced phenomenon?
    Oral surgery, oral medicine, and oral pathology, 1990, Volume: 70, Issue:2

    Topics: Aged; Aged, 80 and over; Atenolol; Bendroflumethiazide; Chlorpropamide; Diabetes Mellitus, Type 2; D

1990