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bendroflumethiazide and Coronary Disease

bendroflumethiazide has been researched along with Coronary Disease in 19 studies

Bendroflumethiazide: A thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)
bendroflumethiazide : A sulfonamide consisting of 7-sulfamoyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide in which the hydrogen at position 6 is substituted by a trifluoromethyl group and that at position 3 is substituted by a benzyl group.

Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.

Research Excerpts

ExcerptRelevanceReference
"The aim of this study was to evaluate the effect of baseline heart rate on the efficacy of atenolol-based compared with amlodipine-based therapy in patients with hypertension uncomplicated by coronary heart disease in the ASCOT-BPLA (Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm)."5.14Baseline heart rate, antihypertensive treatment, and prevention of cardiovascular outcomes in ASCOT (Anglo-Scandinavian Cardiac Outcomes Trial). ( Campbell, NR; Dahlöf, B; Dobson, JE; Poulter, NR; Sever, PS; Wedel, H, 2009)
"Treatment with propranolol in non-smoking men in the highest age and blood pressure categories would lead to a reduction in the number having strokes from three to one or two and might possibly reduce the number experiencing myocardial infarction from seven to four."2.66Stroke and coronary heart disease in mild hypertension: risk factors and the value of treatment. Medical Research Council Working Party. ( , 1988)
"Hypertension is an important risk factor for adverse cardiovascular events including stroke, myocardial infarction, heart failure and renal failure."2.55Pharmacotherapy for hypertension in adults aged 18 to 59 years. ( Gueyffier, F; Musini, VM; Puil, L; Salzwedel, DM; Wright, JM, 2017)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-199014 (73.68)18.7374
1990's1 (5.26)18.2507
2000's3 (15.79)29.6817
2010's1 (5.26)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Musini, VM1
Gueyffier, F1
Puil, L1
Salzwedel, DM1
Wright, JM1
Poulter, NR1
Dobson, JE1
Sever, PS1
Dahlöf, B1
Wedel, H1
Campbell, NR1
JOHNSTON, LC1
GRIEBLE, HG1
SCHOENBERGER, JA1
FULLER, JB1
Füessl, HS1
Rahn, KH1
Cressman, MD1
Gifford, RW1
Christiansen, C2
Christensen, MS2
Hagen, C2
Stocklund, KE2
Transbøl, I2
Jensen, J1
Miall, WE3
Sigurd, B1
Olesen, KH1
Wennevold, A1
Greenberg, G1
Brennan, P1
Dollery, C1
Brennan, PJ1
Breckenridge, A1
Hentzer, L1
Persson, I1

Reviews

2 reviews available for bendroflumethiazide and Coronary Disease

ArticleYear
Pharmacotherapy for hypertension in adults aged 18 to 59 years.
    The Cochrane database of systematic reviews, 2017, 08-16, Volume: 8

    Topics: Adult; Antihypertensive Agents; Bendroflumethiazide; Blood Pressure; Cause of Death; Coronary Diseas

2017
Beta-blockers vs. thiazides in the treatment of hypertension: a review of the experience of the large national trials.
    Journal of cardiovascular pharmacology, 1990, Volume: 16 Suppl 5

    Topics: Adrenergic beta-Antagonists; Bendroflumethiazide; Clinical Trials as Topic; Coronary Disease; Diuret

1990

Trials

10 trials available for bendroflumethiazide and Coronary Disease

ArticleYear
Baseline heart rate, antihypertensive treatment, and prevention of cardiovascular outcomes in ASCOT (Anglo-Scandinavian Cardiac Outcomes Trial).
    Journal of the American College of Cardiology, 2009, Sep-22, Volume: 54, Issue:13

    Topics: Aged; Amlodipine; Antihypertensive Agents; Atenolol; Bendroflumethiazide; Coronary Disease; Europe;

2009
Controversies in hypertension: mild hypertension, isolated systolic hypertension, and the choice of a step one drug.
    Clinical cardiology, 1983, Volume: 6, Issue:1

    Topics: Adult; Aged; Antihypertensive Agents; Bendroflumethiazide; Blood Pressure; Clinical Trials as Topic;

1983
[Effects of natural estrogen/gestagen and thiazide on cardiovascular risk factors in normal menopausal women. A 2-year double-blind placebo study].
    Ugeskrift for laeger, 1981, Aug-24, Volume: 143, Issue:35

    Topics: Adult; Bendroflumethiazide; Coronary Disease; Double-Blind Method; Estrogens; Female; Humans; Menopa

1981
The supra-additive natriuretic effect addition of bendroflumethiazide and bumetanide in congestive heart failure. Permutation trial tests in patients in long-term treatment with bumetanide.
    American heart journal, 1975, Volume: 89, Issue:2

    Topics: Adult; Bendroflumethiazide; Benzoates; Butylamines; Chlorides; Clinical Trials as Topic; Coronary Di

1975
MRC trial of treatment of mild hypertension: principal results. Medical Research Council Working Party.
    British medical journal (Clinical research ed.), 1985, Jul-13, Volume: 291, Issue:6488

    Topics: Adult; Bendroflumethiazide; Blood Pressure; Cerebrovascular Disorders; Clinical Trials as Topic; Cor

1985
Coronary heart disease in the Medical Research Council trial of treatment of mild hypertension. Medical Research Council Working Party on Mild Hypertension.
    British heart journal, 1988, Volume: 59, Issue:3

    Topics: Adult; Bendroflumethiazide; Clinical Trials as Topic; Coronary Disease; Death, Sudden; Female; Human

1988
The mild hypertension dilemma: results of the British MRC trial.
    Journal of clinical hypertension, 1986, Volume: 2, Issue:3 Suppl

    Topics: Adult; Antihypertensive Agents; Bendroflumethiazide; Cardiovascular Diseases; Cerebrovascular Disord

1986
Stroke and coronary heart disease in mild hypertension: risk factors and the value of treatment. Medical Research Council Working Party.
    British medical journal (Clinical research ed.), 1988, Jun-04, Volume: 296, Issue:6636

    Topics: Adult; Age Factors; Bendroflumethiazide; Blood Pressure; Cerebrovascular Disorders; Coronary Disease

1988
Further results of the MRC treatment trial for mild hypertension.
    Nephron, 1987, Volume: 47 Suppl 1

    Topics: Bendroflumethiazide; Cerebrovascular Disorders; Clinical Trials as Topic; Coronary Disease; Death, S

1987
The Medical Research Council Hypertension Trial: the smoking patient.
    American heart journal, 1988, Volume: 115, Issue:1 Pt 2

    Topics: Adult; Bendroflumethiazide; Cerebrovascular Disorders; Coronary Disease; Female; Humans; Hypertensio

1988

Other Studies

7 other studies available for bendroflumethiazide and Coronary Disease

ArticleYear
TREATMENT OF ARTERIAL HYPERTENSIVE DISEASE WITH DIURETICS. III. CHLORTHALIDONE ALONE AND IN COMBINATION WITH SPIRONOLACTONE.
    The American journal of the medical sciences, 1964, Volume: 247

    Topics: Bendroflumethiazide; Cardiomegaly; Chlorides; Chlorthalidone; Coronary Disease; Creatine; Creatinine

1964
[Antihypertensive therapy: campaign of the giants].
    MMW Fortschritte der Medizin, 2005, Dec-15, Volume: 147, Issue:51-52

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Atenolol; Bendroflumethiazide; Coronary Disease; D

2005
[Treating essential hypertension. Are beta blockers still first choice?].
    MMW Fortschritte der Medizin, 2007, May-03, Volume: 149, Issue:18

    Topics: Adrenergic beta-Antagonists; Amlodipine; Antihypertensive Agents; Atenolol; Bendroflumethiazide; Cor

2007
Effects of natural estrogen/gestagen and thiazide on coronary risk factors in normal postmenopausal women. A 2-year double-blind placebo study.
    Acta obstetricia et gynecologica Scandinavica, 1981, Volume: 60, Issue:4

    Topics: Adult; Bendroflumethiazide; Blood Glucose; Blood Pressure; Body Weight; Coronary Disease; Double-Bli

1981
Treating mild hypertension.
    British medical journal (Clinical research ed.), 1985, Jul-13, Volume: 291, Issue:6488

    Topics: Bendroflumethiazide; Cerebrovascular Disorders; Coronary Disease; Female; Humans; Hypertension; Male

1985
Hypertension. I.
    British medical journal, 1971, Jan-02, Volume: 1, Issue:5739

    Topics: Adult; Bendroflumethiazide; Cerebrovascular Disorders; Coronary Disease; Diuretics; Female; Humans;

1971
Small bowel ulceration. An evaluation of thiazide therapy.
    Geriatrics, 1968, Volume: 23, Issue:1

    Topics: Aged; Bendroflumethiazide; Biphenyl Compounds; Burns, Chemical; Coronary Disease; Delayed-Action Pre

1968