bendazac has been researched along with Chemical and Drug Induced Liver Injury in 9 studies
bendazac : A monocarboxylic acid that is glycolic acid in which the hydrogen attached to the 2-hydroxy group is replaced by a 1-benzyl-1H-indazol-3-yl group. Although it has anti-inflammatory, antinecrotic, choleretic and antilipidaemic properties and has been used for the treatment of various inflammatory skin disorders, its principal effect is to inhibit the denaturation of proteins. Its lysine salt is used in the management of cataracts.
Chemical and Drug Induced Liver Injury: A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We proposed a systematic classification scheme using FDA-approved drug labeling to assess the DILI potential of drugs, which yielded a benchmark dataset with 287 drugs representing a wide range of therapeutic categories and daily dosage amounts." | 1.37 | FDA-approved drug labeling for the study of drug-induced liver injury. ( Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V, 2011) |
| "This NSAID is used in Spain for the treatment of cataracts, from a total of 112 patients observing such therapy." | 1.29 | [Bendazac hepatotoxicity: analysis of 16 cases]. ( del Portillo Rubí, A; Prada Mínguez, A; Prieto de Paula, JM; Rodríguez Rodríguez, E; Sanz de la Fuente, H; Villamandos Nicás, V, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 4 (44.44) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (44.44) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fourches, D | 1 |
| Barnes, JC | 1 |
| Day, NC | 1 |
| Bradley, P | 1 |
| Reed, JZ | 1 |
| Tropsha, A | 1 |
| Chen, M | 2 |
| Vijay, V | 1 |
| Shi, Q | 2 |
| Liu, Z | 2 |
| Fang, H | 2 |
| Tong, W | 3 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Suzuki, A | 1 |
| Thakkar, S | 1 |
| Yu, K | 1 |
| Hu, C | 1 |
| Prieto de Paula, JM | 3 |
| Rodríguez Rodríguez, E | 2 |
| Villamandos Nicás, V | 2 |
| Sanz de la Fuente, H | 1 |
| Prada Mínguez, A | 1 |
| del Portillo Rubí, A | 1 |
| Cancelo Suárez, P | 2 |
| Echevarría Iturbe, C | 1 |
| Alcalde, M | 1 |
| García-Díaz, M | 1 |
| Najarro, F | 1 |
| Pascasio, JM | 1 |
| Sánchez Sánchez, A | 1 |
| Ballesteros, JA | 1 |
| Badosa, AM | 1 |
| Usandizaga, I | 1 |
| Amengual, M | 1 |
2 reviews available for bendazac and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr | 2016 |
[Chronic active hepatitis due to bendazac].
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Chemical and Drug Induced Liver Injury; Chemi | 1994 |
7 other studies available for bendazac and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Des | 2011 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
[Bendazac hepatotoxicity: analysis of 16 cases].
Topics: Age Factors; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cataract; Chemical an | 1995 |
[Toxic and autoimmune type I-like hepatitis and hyporegenerative anemia caused by bendazac].
Topics: Aged; Aged, 80 and over; Anemia, Aplastic; Anti-Inflammatory Agents, Non-Steroidal; Autoimmune Disea | 1994 |
[Toxic hepatitis caused by bendazac].
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver In | 1993 |
Hepatotoxicity due to bindazac.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Cataract; Chemical and Drug Induced Liver Injury; Fem | 1987 |