Page last updated: 2024-08-25

bendamustine hydrochloride and Kahler Disease

bendamustine hydrochloride has been researched along with Kahler Disease in 85 studies

Research

Studies (85)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's14 (16.47)29.6817
2010's57 (67.06)24.3611
2020's14 (16.47)2.80

Authors

AuthorsStudies
Gogia, A; Gupta, R; Kumar, L; Kumar, S; Malik, PS; Pathak, N; Prasad, CP; Sahoo, RK; Sharma, A1
Bashey, A; Brown, S; Holland, HK; Jackson, KC; Morris, LE; Shegda, N; Solh, M; Solomon, SR; Zhang, X1
Akhtar, S; Brouwer, R; Drayson, M; Dunn, J; Iqbal, G; Lindsay, J; Ramasamy, K; Schey, S; Stalker, V; Varghese, S1
Costa, BA; Mouhieddine, TH; Ortiz, RJ; Richter, J1
Ballestrero, A; Calabrese, M; Ceccardi, A; Cuccarolo, P; Dameri, M; Garlaschi, A; Gristina, L; Stabile, M; Tagliafico, A; Valente, I; Zoppoli, G1
Fu, CC; Jin, S; Ma, X; Shang, JJ; Wang, J; Wu, DP; Yao, Y1
Chu, XX; Deng, XZ; Fan, CB; Hao, HY; Liu, GQ; Ran, XH; Wu, HY; Yuan, CL; Zhong, YP; Zhou, X1
Arai, S; Bharadwaj, S; Budde, LE; Dahiya, S; Frank, MJ; Goyal, A; Hosoya, H; Hovanky, V; Htut, M; Janakiram, M; Jensen, A; Latchford, T; Leahy, S; Liu, L; Mei, M; Miklos, D; Muffly, LS; Sahaf, B; Sidana, S1
Assal, A; Bhutani, D; Hu, J; Leng, S; Lentzsch, S; Mapara, M; Pan, S; Raza, S; Wei, A1
Fiala, MA; Ghobadi, A; Goldsmith, SR; Schroeder, MA; Stockerl-Goldstein, K; Vij, R; Wang, B; Wildes, TM1
Dingeldein, G; Goldschmidt, H; Habermehl, C; Knauf, W; Kunz, C; Moehler, T; Raab, MS; Schlag, R; Terzer, T; Walter, S; Welslau, M1
Andrea, M; Becker, C; Bill, M; Braunert, L; Edelmann, T; Franke, GN; Grimm, J; Hammerschmidt, D; Hoffmann, FA; Holzhey, T; Holzvogt, B; Holzvogt, M; Jentzsch, M; Platzbecker, U; Pönisch, W; Remane, Y; Scholz, M; Schönfelder-Fricke, U; Schwarz, M; Schwarzer, A; Schwind, S; Wang, SY; Zehrfeld, T1
Badillo, M; Chen, W; Feng, L; Graham, V; Jain, P; Lee, HC; Lee, HJ; Lu, R; Manasanch, EE; Oriabure, O; Orlowski, RZ; Wang, ML1
Aquino, S; Boccadoro, M; Corradini, P; Einsele, H; Engelhardt, M; Gay, F; Gentili, S; Gramatzki, M; Günther, A; Montefusco, V; Offidani, M; Palumbo, A; Patriarca, F; Pönisch, W; Salvini, M; Schub, N; Sonneveld, P; Spada, S; Straka, C; Wäsch, R1
Bergsagel, PL; Chesi, M; Garayoa, M; González-Díaz, M; González-Méndez, L; Gutiérrez, NC; Hernández-García, S; Herrero, AB; López-Iglesias, AA; Martín-Sánchez, M; Mateos, MV; Mehrling, T; Misiewicz-Krzeminska, I; Ocio, EM; Paíno, T; Primo, D; Quwaider, D; San-Miguel, JF; San-Segundo, L1
Andrea, M; Beck, J; Becker, C; Bill, M; Edelmann, T; Gläser, D; Heyn, S; Hoffmann, FA; Jentzsch, M; Kragl, B; Kreibich, U; Lange, T; Mohren, M; Mügge, LO; Niederwieser, D; Pönisch, W; Schliwa, T; Schwarzer, A; Schwind, S; Uhlig, J; Winkelmann, C; Zehrfeld, T1
Campioni, M; DeCosta, L; Fink, L; Flinois, A; Gazzola, C; Gonzalez-McQuire, S; Leleu, H; Mennini, FS; Schoen, P; Yong, K1
Chao, NJ; Garrett, AH; Gasparetto, C; Green, MM; Kang, Y; Li, Z; Long, GD; McIntyre, JL; Rizzieri, DA; Sivaraj, D1
Badiali, S; Billio, A; Cappelletto, PC; Cortelazzo, S; Luminari, S; Marabese, A; Marcheselli, L; Mian, M; Mondello, P; Pascarella, A; Patriarca, F; Pescosta, N; Tagariello, G; Zambello, R1
Bacher, U; Betticher, D; Brégy, R; Egger, T; Farag, SA; Jeker, B; Mansouri Taleghani, B; Novak, U; Pabst, T; Prediletto, I; Zander, T1
Christos, PJ; Coleman, M; Gergis, U; Gomez-Arteaga, A; Greenberg, JD; Guarneri, D; Hsu, J; Mark, TM; Mayer, SA; Niesvizky, R; Pearse, RN; Phillips, AA; Rossi, A; Shore, TB; van Besien, K1
Goldschmidt, H; Kropff, M; Mügge, LO; Pönisch, W1
Coleman, M; Gergis, U; Greenberg, J; Mark, TM; Mayer, S; Niesvizky, R; Pearse, R; Reid, W; Shore, T; Van Besien, K1
Cai, B; Gao, C; Huang, J; Lee, CK; Liu, B; Lyu, H; Wang, S1
Bell, S; Bird, J; Bowcock, S; Cavenagh, J; Cook, G; D'Sa, S; Davies, F; Lai, M; Morgan, G; Owen, R; Pratt, G; Snowden, JA; Yong, K1
Huang, B; Li, J; Liu, J; Lu, B; Pan, J; Zheng, D1
Al-Ali, HK; Beck, J; Edelmann, T; Hebenstreit, K; Heyn, S; Hoffmann, FA; Jäkel, N; Lange, T; Mohren, M; Niederwieser, D; Pönisch, W; Röhrborn, R; Schmalfeld, M; Schwarzer, A; Wagner, I; Winkelmann, C; Zehrfeld, T1
Giannotta, A; Guaragna, G; Mele, G; Melpignano, A; Quarta, G; Spina, A1
Al Ali, H; Andrea, M; Bachmann, A; Becker, C; Bourgeois, M; Edelmann, T; Egert, M; Fricke, S; Heyn, S; Hoffmann, FA; Krahl, R; Kreibich, U; Lindner, T; Moll, B; Niederwieser, D; Petros, S; Pönisch, W; Remane, Y; Schliwa, T; Schmalfeld, M; Schwarzer, A; Stiegler, R; Vucinic, V; Weidhase, L1
Bossio, S; De Stefano, L; Gentile, M; Granata, T; Lucia, E; Martino, M; Mazzone, C; Morabito, F; Morabito, L; Palummo, A; Recchia, AG; Vigna, E1
Adam, Z; Greil, R; Kasparu, H; Leitgeb, C; Linkesch, W; Ludwig, H; Pour, L; Rauch, E; Seebacher, A; Weißmann, A; Zojer, N1
Amiot, M; Descamps, G; Le Gouill, S; Lemieux-Blanchard, E; Maïga, S; Moreau, P; Pellat-Deceunynck, C; Surget, S1
Lerner, R; Nahi, H; Svedmyr, E1
Motlló, C; Oriol, A1
Lentzsch, S1
Akutsu, M; Furukawa, Y; Hiraoka, N; Kano, Y; Kikuchi, J; Koyama, D; Mori, S; Nakamura, Y; Ueda, T; Uesawa, M; Wada, T; Yamauchi, T1
Cavo, M; Offidani, M; Palumbo, A; Patriarca, F; Petrucci, MT1
Andrea, M; Becker, C; Behre, G; Bourgeois, M; Edelmann, T; Gutsche, K; Hammerschmidt, D; Hennig, E; Heyn, S; Hoffmann, FA; Holzvogt, B; Kaiser, T; Krahl, R; Kreibich, U; Lindner, T; Niederwieser, D; Plötze, M; Pönisch, W; Reifenrath, K; Remane, Y; Schliwa, T; Schwarz, M; Schwarzer, A; Vucinic, V; Winkelmann, C; Zehrfeld, T1
Aujesky, D; Oestmann, A1
Chim, CS; Wong, KY1
Nakaseko, C1
Aitchison, R; Blesing, N; Lau, IJ; Peniket, A; Rabin, N; Ramasamy, K; Roberts, P; Smith, D; Yong, K1
Gertz, MA2
Anglaret, B; Avet-Loiseau, H; Banos, A; Benboubker, L; Benramdane, R; Casassus, P; Chaleteix, C; Cony-Makhoul, P; Decaux, O; Dejoie, T; Dib, M; Fitoussi, O; Fontan, J; Garderet, L; Hulin, C; Jardel, H; Kolb, B; Leleu, X; Lenain, P; Mathiot, C; Moreau, P; Pegourie, B; Pétillon, MO; Rodon, P; Roussel, M; Royer, B; Stoppa, AM; Tiab, M; Traullé, C; Vilque, JP1
Andriani, A; Baldini, L; Ballanti, S; Baraldi, A; Bongarzoni, V; Califano, C; Derudas, D; Falcone, A; Fragasso, A; Fraticelli, VL; Madonna, E; Mansueto, G; Mele, G; Mussetti, A; Musto, P; Nozza, A; Patriarca, F; Storti, S; Vincelli, D; Zambello, R1
Becker, N; Benner, A; Breitkreutz, I; Egerer, G; Goldschmidt, H; Heining, C; Hillengass, J; Ho, AD; Kosely, F; Raab, MS1
Brown, SR; Cavenagh, J; Cavet, J; Cook, G; Cook, M; Davies, F; Flanagan, L; Gregory, W; Morgan, G; Morris, C; Orti, G; Schey, S; Sherratt, D; Tillotson, AL; Williams, C; Yong, K1
AlAli, HK; Andrea, M; Becker, C; Edelmann, T; Franke, GN; Gutsche, K; Hammerschmidt, D; Heyn, S; Hoffmann, FA; Holzvogt, B; Jentzsch, M; Kreibich, U; Lange, T; Leiblein, S; Niederwieser, D; Plötze, M; Poenisch, W; Reifenrath, K; Schliwa, T; Schwarz, M; Schwarzbach, H; Schwarzer, A; Schwind, S; Vucinic, V; Zehrfeld, T1
Gentile, M; Giagnuolo, G; Mendicino, F; Morabito, F; Morabito, L; Recchia, AG; Vigna, E1
Hänel, M; Schmeel, FC; Schmeel, LC; Schmidt-Wolf, IG; Stöhr, E1
Casado, F; de la Fuente, A; de la Rubia, J; Debén, G; Delgado, J; Echeveste, A; Grande, C; Lahuerta, JJ; Loscertales, J; Mateos, MV; Olave, MT; Osorio, S; Peña, A; Peñalver, FJ; Pérez Ceballos, E; Salar, A; Sastre, JL1
Birgin, A; Buadi, FK; Duarte, L; Fiala, M; Gertz, MA; Krishnan, A; Kumar, SK; LaPlant, B; Laumann, K; Levy, J; Maharaj, M; Roy, V; Stockerl Goldstein, K; Vij, R; Zimmerman, T1
Berardi, M; Biagioli, T; Bosi, A; Brogi, M; Caldini, A; Nozzoli, C; Staderini, M; Terreni, A1
Brunetti, G; Cartoni, C; Chisini, M; Finsinger, P; Foà, R; Gentilini, F; Petrucci, MT1
Pecherstorfer, M; Zwickl, H; Zwickl-Traxler, E1
Console, G; Gentile, M; Martino, M; Messina, G; Molica, S; Morabito, F; Recchia, AG; Tripepi, G; Vincelli, ID1
Badiali, S; Bari, A; Cocito, F; Corso, A; Gentile, M; Guarini, A; Marcheselli, L; Marcheselli, R; Mazzone, C; Mele, G; Minoia, C; Morabito, F; Musto, P; Palumbo, A; Pozzi, S; Ria, R; Rivolti, E; Sacchi, S; Vincelli, I1
Akkoç, N; Ar, MC; Aydın, Y; Eşkazan, AE; Öngören, Ş; Salihoğlu, A; Soysal, T; Yalnız, FF1
Boldt, T; Goldschmidt, H; Haas, A; Hoffmann, FA; Kreibich, U; Niederwieser, D; Pönisch, W; Ritter, U; Rohrberg, R; Rozanski, M; Schirmer, V; Schwalbe, E; Schwarzer, A; Uhlig, J; Zehrfeld, T1
Stewart, AK1
Bölke, E; Bruns, I; Czibere, A; Fenk, R; Haas, R; Kobbe, G; Michael, M; Neumann, F; Safaian, NN; Zohren, F1
Cheson, BD; Dreyling, M; Friedberg, J; Gribben, J; Hoelzer, D; Knop, S; Montillo, M; Moreau, P; Pieper, A; Rummel, M; Wendtner, CM1
Fiore, J; Kozyreva, O; May, SK; Tapan, U1
Corderoy, S; Hazel, B; Mahmood, S; Ramasamy, K; Schey, S1
Hata, H1
Banos, A; Caillot, D; Damaj, G; Fitoussi, O; Garidi, R; Hulin, C; Malard, F; Marit, G; Moreau, P; Morineau, N; Royer, B; Stoppa, AM; Tiab, M1
Abbas, M; Agha, M; Boyiadzis, M; Burt, S; Dai, L; Kennedy, RC; Lentzsch, S; Mapara, MY; Normolle, D; O'Sullivan, A; Pregja, SL; Roodman, GD; Shuai, Y; Waas, J; Zonder, JA1
Andrea, M; Bachmann, A; Hammerschmidt, D; Kreibich, U; Lindner, T; Niederwieser, D; Petros, S; Pönisch, W; Schwarz, M; Schwarzer, A; Wagner, I; Winkelmann, C; Zehrfeld, T1
Hoy, SM1
Berenson, JR; Bessudo, A; Boccia, RV; Gorak, EJ; Gravenor, DS; Kewalramani, T; Mayo, D; Nassir, Y; Noga, SJ; Patel-Donnelly, D; Siegel, RS; Swift, RA; Yellin, O1
Ali, HA; Aßmann, M; Becker, C; Bourgeois, M; Edelmann, T; Hensel, G; Heyn, S; Hoffmann, FA; Hurtz, HJ; Jäkel, N; Krahl, R; Löschcke, K; Mohren, M; Moll, B; Niederwieser, D; Pönisch, W; Rohrberg, R; Schmalfeld, M; Schönfelder, U; Schwarzer, A; Wagner, I; Zehrfeld, T1
Alsina, M; Anderson, KC; Bensinger, W; Biermann, JS; Cohen, AD; Devine, S; Djulbegovic, B; Faber, EA; Gasparetto, C; Hernandez-Illizaliturri, F; Huff, CA; Kassim, A; Krishnan, AY; Kumar, R; Liedtke, M; Meredith, R; Raje, N; Schriber, J; Shead, DA; Singhal, S; Somlo, G; Stockerl-Goldstein, K; Treon, SP; Weber, D; Yahalom, J; Yunus, F1
Cheson, BD; Diehl, V1
Gandhi, V1
Schrijvers, D; Vermorken, JB1
Niederwieser, D; Pönisch, W1
Cheson, BD1
Bremer, K1
Einsele, H; Haen, M; Hebart, H; Knop, S; Schwedes, R; Straka, C1
Assmann, M; Bittrich, A; Dachselt, K; Freund, M; Friedrich, T; Grobe, N; Harksel, B; Helbig, W; Herold, M; Merkle, K; Mitrou, PS; Niederwieser, D; Pasold, R; Pönisch, W; Richter, P; Schirmer, V; Schulze, A; Schulze, M; Stelzer, E; Subert, R; Wilhelm, G1
Baumann, P; Emmerich, B; Gaul, L; Mandl-Weber, S; Schmidmaier, R1
Baumann, P; Bumeder, I; Emmerich, B; Meinhardt, G; Schmidmaier, R; Straka, C1
Bruns, I; Czibere, A; Fenk, B; Fenk, R; Graef, T; Haas, R; Kobbe, G; Michael, M; Neumann, F; Zohren, F1

Reviews

13 review(s) available for bendamustine hydrochloride and Kahler Disease

ArticleYear
Revisiting the role of alkylating agents in multiple myeloma: Up-to-date evidence and future perspectives.
    Critical reviews in oncology/hematology, 2023, Volume: 187

    Topics: Alkylating Agents; Bendamustine Hydrochloride; Cyclophosphamide; Humans; Multiple Myeloma; Receptors, Chimeric Antigen

2023
An old drug with a new future: bendamustine in multiple myeloma.
    Expert opinion on pharmacotherapy, 2013, Volume: 14, Issue:16

    Topics: Alkylating Agents; Bendamustine Hydrochloride; Humans; Multiple Myeloma; Nitrogen Mustard Compounds; Treatment Outcome

2013
[New drugs in the treatment of multiple myeloma].
    Medicina clinica, 2014, Sep-15, Volume: 143, Issue:6

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Clinical Trials as Topic; Drug Synergism; Drugs, Investigational; Histone Deacetylase Inhibitors; Humans; Immunologic Factors; Molecular Targeted Therapy; Multiple Myeloma; Nitrogen Mustard Compounds; Protease Inhibitors; Protein Kinase Inhibitors; Thalidomide

2014
Bendamustine for the treatment of multiple myeloma in first-line and relapsed-refractory settings: a review of clinical trial data.
    Leukemia & lymphoma, 2015, Volume: 56, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Bendamustine Hydrochloride; Clinical Trials as Topic; Humans; Multiple Myeloma; Neoplasm Recurrence, Local

2015
[Treatment of transplant-eligible symptomatic multiple myeloma].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2014, Volume: 55, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Autografts; Bendamustine Hydrochloride; Boronic Acids; Bortezomib; Combined Modality Therapy; Consolidation Chemotherapy; Cyclophosphamide; Dexamethasone; Drug Discovery; Hematopoietic Stem Cell Transplantation; Humans; Induction Chemotherapy; Lenalidomide; Maintenance Chemotherapy; Melphalan; Multiple Myeloma; Neoplasm, Residual; Nitrogen Mustard Compounds; Pyrazines; Remission Induction; Thalidomide; Transplantation Conditioning

2014
Bendamustine in multiple myeloma.
    European journal of haematology, 2015, Volume: 95, Issue:5

    Topics: Autografts; Bendamustine Hydrochloride; Humans; Multiple Myeloma; Peripheral Blood Stem Cell Transplantation; Transplantation Conditioning

2015
Novel therapies for relapsed myeloma.
    Hematology. American Society of Hematology. Education Program, 2009

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Boronic Acids; Bortezomib; Clinical Trials as Topic; Drug Administration Schedule; Drug Screening Assays, Antitumor; Drugs, Investigational; Heat-Shock Proteins; Histone Deacetylase Inhibitors; Humans; Immunologic Factors; Mice; Mice, Transgenic; Multiple Myeloma; Neoplasm Proteins; Nitrogen Mustard Compounds; Oligopeptides; Protease Inhibitors; Proteasome Inhibitors; Proto-Oncogene Proteins c-akt; Pyrazines; Salvage Therapy; Thalidomide

2009
Optimal use of bendamustine in chronic lymphocytic leukemia, non-Hodgkin lymphomas, and multiple myeloma: treatment recommendations from an international consensus panel.
    Clinical lymphoma, myeloma & leukemia, 2010, Volume: 10, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Drug Administration Schedule; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Non-Hodgkin; Multiple Myeloma; Nitrogen Mustard Compounds

2010
[Development of novel agents for multiple myeloma; now and the future].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2011, Volume: 52, Issue:8

    Topics: Animals; Antibodies, Monoclonal, Humanized; Bendamustine Hydrochloride; Benzoquinones; Benzylamines; Clinical Trials as Topic; Cyclams; Drug Discovery; Drug Therapy, Combination; Heterocyclic Compounds; Humans; Hydroxamic Acids; Lactams, Macrocyclic; Molecular Targeted Therapy; Multiple Myeloma; Nitrogen Mustard Compounds; Oligopeptides; Thalidomide; Vorinostat

2011
Bendamustine: a review of its use in the management of chronic lymphocytic leukaemia, rituximab-refractory indolent non-Hodgkin's lymphoma and multiple myeloma.
    Drugs, 2012, Oct-01, Volume: 72, Issue:14

    Topics: Antineoplastic Agents, Alkylating; Bendamustine Hydrochloride; Disease-Free Survival; Dose-Response Relationship, Drug; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Non-Hodgkin; Multiple Myeloma; Nitrogen Mustard Compounds; Randomized Controlled Trials as Topic; Retrospective Studies

2012
Metabolism and mechanisms of action of bendamustine: rationales for combination therapies.
    Seminars in oncology, 2002, Volume: 29, Issue:4 Suppl 13

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Chlorambucil; DNA Repair; Drug Synergism; G2 Phase; Humans; Immunologic Factors; Multiple Myeloma; Nitrogen Mustard Compounds; S Phase

2002
Phase I studies with bendamustine: an update.
    Seminars in oncology, 2002, Volume: 29, Issue:4 Suppl 13

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Drug Administration Schedule; Europe; Hematologic Neoplasms; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Lymphopenia; Multiple Myeloma; Nitrogen Mustard Compounds; Research Design

2002
Hematologic malignancies: new developments and future treatments.
    Seminars in oncology, 2002, Volume: 29, Issue:4 Suppl 13

    Topics: Adenine Nucleotides; Alemtuzumab; Alkaloids; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Antibodies, Neoplasm; Antineoplastic Agents; Apoptosis; Arabinonucleosides; Bendamustine Hydrochloride; Boronic Acids; Bortezomib; Cell Cycle; Cell Survival; Clofarabine; Cytosine; Dioxolanes; Flavonoids; Hematologic Neoplasms; Humans; Immunoconjugates; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Lymphoma, Non-Hodgkin; Multiple Myeloma; NF-kappa B; Nitrogen Mustard Compounds; Oligonucleotides, Antisense; Peptide Hydrolases; Piperidines; Protease Inhibitors; Proteasome Endopeptidase Complex; Pyrazines; Remission Induction; Rituximab; Staurosporine; Thionucleotides

2002

Trials

27 trial(s) available for bendamustine hydrochloride and Kahler Disease

ArticleYear
Bendamustine in combination with pomalidomide and dexamethasone in relapsed/refractory multiple myeloma: A phase II trial.
    British journal of haematology, 2022, Volume: 198, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Dexamethasone; Female; Humans; Lenalidomide; Male; Middle Aged; Multiple Myeloma; Thalidomide

2022
High-Dose Bendamustine, Etoposide, Cytarabine, and Melphalan (BeEAM) Conditioning Before Autologous Transplantation for Patients With Multiple Myeloma.
    Transplantation and cellular therapy, 2022, Volume: 28, Issue:8

    Topics: Bendamustine Hydrochloride; Cytarabine; Drug Therapy, Combination; Etoposide; Hematopoietic Stem Cell Transplantation; Humans; Melphalan; Multiple Myeloma; Neoplasm Recurrence, Local; Transplantation, Autologous

2022
Bortezomib, Bendamustine and Dexamethasone vs Thalidomide, Bendamustine and Dexamethasone in Myeloma patients presenting with renal failure (OPTIMAL): a randomised, multi-centre phase II trial.
    Blood cancer journal, 2022, 11-29, Volume: 12, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Bortezomib; Dexamethasone; Humans; Multiple Myeloma; Renal Insufficiency; Thalidomide

2022
Phase I/II study of carfilzomib, bendamustine, and dexamethasone (CBD) in patients with newly diagnosed multiple myeloma.
    Blood cancer journal, 2020, 02-03, Volume: 10, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Dexamethasone; Female; Follow-Up Studies; Humans; Male; Middle Aged; Multiple Myeloma; Oligopeptides; Prognosis

2020
First-line therapy with bendamustine/prednisone/bortezomib-A GMMG trial for non-transplant eligible symptomatic multiple myeloma patients.
    European journal of haematology, 2020, Volume: 105, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Biomarkers, Tumor; Bortezomib; Female; Humans; Male; Middle Aged; Multiple Myeloma; Neoplasm Staging; Prednisone; Prognosis; Progression-Free Survival; Renal Insufficiency; Treatment Outcome

2020
A phase one trial of carfilzomib, bendamustine, and dexamethasone in relapsed and/or refractory multiple myeloma.
    American journal of hematology, 2021, 07-01, Volume: 96, Issue:7

    Topics: Aged; Antineoplastic Agents; Bendamustine Hydrochloride; Dexamethasone; Female; Humans; Male; Middle Aged; Multiple Myeloma; Neoplasm Recurrence, Local; Oligopeptides; Treatment Outcome

2021
Carfilzomib, bendamustine, and dexamethasone in patients with advanced multiple myeloma: The EMN09 phase 1/2 study of the European Myeloma Network.
    Cancer, 2021, 09-15, Volume: 127, Issue:18

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Dexamethasone; Humans; Multiple Myeloma; Neoplasm Recurrence, Local; Oligopeptides

2021
Lenalidomide in combination with bendamustine and prednisolone in relapsed/refractory multiple myeloma: results of a phase 2 clinical trial (OSHO-#077).
    Journal of cancer research and clinical oncology, 2017, Volume: 143, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Disease-Free Survival; Female; Humans; Lenalidomide; Male; Middle Aged; Multiple Myeloma; Prednisolone; Prospective Studies; Thalidomide

2017
Phase II trial to investigate efficacy and safety of bendamustine, dexamethasone and thalidomide in relapsed or refractory multiple myeloma patients after treatment with lenalidomide and bortezomib.
    British journal of haematology, 2019, Volume: 185, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Bortezomib; Dexamethasone; Female; Humans; Male; Middle Aged; Multiple Myeloma; Thalidomide

2019
High-dose bendamustine and melphalan conditioning for autologous stem cell transplantation for patients with multiple myeloma.
    Bone marrow transplantation, 2019, Volume: 54, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Female; Humans; Male; Melphalan; Middle Aged; Multiple Myeloma; Transplantation, Autologous; Young Adult

2019
A phase 1 study of bendamustine and melphalan conditioning for autologous stem cell transplantation in multiple myeloma.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2013, Volume: 19, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Combined Modality Therapy; Dose-Response Relationship, Drug; Female; Hematopoietic Stem Cell Transplantation; Humans; Male; Melphalan; Middle Aged; Multiple Myeloma; Nitrogen Mustard Compounds; Transplantation Conditioning; Transplantation, Autologous

2013
Lenalidomide, bendamustine and prednisolone exhibits a favourable safety and efficacy profile in relapsed or refractory multiple myeloma: final results of a phase 1 clinical trial OSHO - #077.
    British journal of haematology, 2013, Volume: 162, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Humans; Lenalidomide; Male; Middle Aged; Multiple Myeloma; Nitrogen Mustard Compounds; Prednisolone; Recurrence; Thalidomide

2013
Bendamustine-bortezomib-dexamethasone is an active and well-tolerated regimen in patients with relapsed or refractory multiple myeloma.
    Blood, 2014, Feb-13, Volume: 123, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Boronic Acids; Bortezomib; Dexamethasone; Drug Resistance, Neoplasm; Female; Humans; Male; Middle Aged; Multiple Myeloma; Nitrogen Mustard Compounds; Pyrazines; Recurrence; Survival Analysis

2014
Phase II study of bendamustine, bortezomib and dexamethasone as second-line treatment for elderly patients with multiple myeloma: the Intergroupe Francophone du Myelome 2009-01 trial.
    Haematologica, 2015, Volume: 100, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Boronic Acids; Bortezomib; Dexamethasone; Female; Follow-Up Studies; Humans; Male; Multiple Myeloma; Neoplasm Grading; Neoplasm Recurrence, Local; Nitrogen Mustard Compounds; Prognosis; Pyrazines; Survival Rate

2015
Bendamustine, thalidomide and dexamethasone combination therapy for relapsed/refractory myeloma patients: results of the MUKone randomized dose selection trial.
    British journal of haematology, 2015, Volume: 170, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Dexamethasone; Disease-Free Survival; Female; Humans; Male; Middle Aged; Multiple Myeloma; Nitrogen Mustard Compounds; Survival Rate; Thalidomide

2015
Bendamustine, lenalidomide, and dexamethasone (BRD) is highly effective with durable responses in relapsed multiple myeloma.
    American journal of hematology, 2015, Volume: 90, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Dexamethasone; Female; Humans; Lenalidomide; Male; Middle Aged; Multiple Myeloma; Thalidomide

2015
Bendamustine and dexamethasone are an effective salvage regimen for patients with advanced multiple myeloma in a Home Care Unit program.
    Leukemia & lymphoma, 2016, Volume: 57, Issue:7

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Dexamethasone; Disease-Free Survival; Female; Home Care Services; Humans; Male; Middle Aged; Multiple Myeloma; Salvage Therapy; Treatment Outcome

2016
A phase II, single-arm, prospective study of bendamustine plus melphalan conditioning for second autologous stem cell transplantation in de novo multiple myeloma patients through a tandem transplant strategy.
    Bone marrow transplantation, 2016, Volume: 51, Issue:9

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Diarrhea; Female; Graft Survival; Hematopoietic Stem Cell Transplantation; Humans; Male; Melphalan; Middle Aged; Mucositis; Multiple Myeloma; Transplantation Conditioning; Treatment Outcome; Vomiting

2016
Bendamustine, Low-dose dexamethasone, and lenalidomide (BdL) for the treatment of patients with relapsed/refractory multiple myeloma confirms very promising results in a phase I/II study.
    Leukemia & lymphoma, 2017, Volume: 58, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Biomarkers; Dexamethasone; Disease Progression; Drug Resistance, Neoplasm; Female; Humans; Lenalidomide; Male; Maximum Tolerated Dose; Middle Aged; Multiple Myeloma; Neoplasm Staging; Recurrence; Retreatment; Survival Analysis; Thalidomide; Treatment Outcome

2017
Combined bendamustine, prednisolone and thalidomide for refractory or relapsed multiple myeloma after autologous stem-cell transplantation or conventional chemotherapy: results of a Phase I clinical trial.
    British journal of haematology, 2008, Volume: 143, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Combined Modality Therapy; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Multiple Myeloma; Nitrogen Mustard Compounds; Prednisolone; Recurrence; Statistics, Nonparametric; Stem Cell Transplantation; Survival Rate; Thalidomide; Transplantation, Autologous

2008
Bendamustine in combination with thalidomide and dexamethasone is an effective therapy for myeloma patients with end stage renal disease.
    British journal of haematology, 2011, Volume: 155, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Dexamethasone; Drug Therapy, Combination; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Multiple Myeloma; Nitrogen Mustard Compounds; Thalidomide

2011
Combination of bendamustine, lenalidomide, and dexamethasone (BLD) in patients with relapsed or refractory multiple myeloma is feasible and highly effective: results of phase 1/2 open-label, dose escalation study.
    Blood, 2012, May-17, Volume: 119, Issue:20

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Dexamethasone; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Feasibility Studies; Female; Humans; Lenalidomide; Male; Middle Aged; Multiple Myeloma; Nitrogen Mustard Compounds; Recurrence; Thalidomide; Treatment Outcome

2012
Phase I/II trial assessing bendamustine plus bortezomib combination therapy for the treatment of patients with relapsed or refractory multiple myeloma.
    British journal of haematology, 2013, Volume: 160, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Boronic Acids; Bortezomib; Female; Humans; Male; Middle Aged; Multiple Myeloma; Neoplasm Staging; Nitrogen Mustard Compounds; Pyrazines; Recurrence; Treatment Outcome

2013
Bendamustine in the treatment of multiple myeloma: results and future perspectives.
    Seminars in oncology, 2002, Volume: 29, Issue:4 Suppl 13

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Cyclophosphamide; Female; Humans; Male; Melphalan; Middle Aged; Multiple Myeloma; Nitrogen Mustard Compounds; Prednisolone; Prednisone; Prospective Studies; Remission Induction; Survival Rate

2002
High rates of long-lasting remissions after 5-day bendamustine chemotherapy cycles in pre-treated low-grade non-Hodgkin's-lymphomas.
    Journal of cancer research and clinical oncology, 2002, Volume: 128, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Bendamustine Hydrochloride; Female; Hematologic Diseases; Humans; Infusions, Intravenous; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocytes; Lymphoma, Follicular; Lymphoma, Non-Hodgkin; Lymphopenia; Male; Maximum Tolerated Dose; Middle Aged; Multiple Myeloma; Neoplasm Recurrence, Local; Nitrogen Mustard Compounds; Prognosis; Remission Induction; Salvage Therapy; Survival Rate

2002
Treatment of bendamustine and prednisone in patients with newly diagnosed multiple myeloma results in superior complete response rate, prolonged time to treatment failure and improved quality of life compared to treatment with melphalan and prednisone--a
    Journal of cancer research and clinical oncology, 2006, Volume: 132, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Disease-Free Survival; Female; Germany, East; Humans; Male; Melphalan; Middle Aged; Multiple Myeloma; Nitrogen Mustard Compounds; Prednisone; Quality of Life; Remission Induction; Survival Analysis; Time Factors; Treatment Failure

2006
First clinical experience with simvastatin to overcome drug resistance in refractory multiple myeloma.
    European journal of haematology, 2007, Volume: 79, Issue:3

    Topics: Bendamustine Hydrochloride; Boronic Acids; Bortezomib; Cell Adhesion; Drug Resistance, Neoplasm; Feasibility Studies; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Multiple Myeloma; Nitrogen Mustard Compounds; Pyrazines; Salvage Therapy; Simvastatin

2007

Other Studies

45 other study(ies) available for bendamustine hydrochloride and Kahler Disease

ArticleYear
Complete pathological response of hormone receptor positive invasive breast cancer in a patient with multiple myeloma treated with ixazomib.
    Tumori, 2023, Volume: 109, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Breast Neoplasms; Dexamethasone; Female; Humans; Multiple Myeloma; Neoplasm Recurrence, Local; Recurrence

2023
[Efficacy and safety of bendamustine combined with pomalidomide and dexamethasone in patients with relapsed and refractory multiple myeloma].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2023, Jun-14, Volume: 44, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Dexamethasone; Humans; Multiple Myeloma; Neoplasm Recurrence, Local

2023
[Bendamustine combined with pomalidomide and dexamethasone in relapsed multiple myeloma with extramedullary disease: a multicenter study].
    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2023, Aug-14, Volume: 44, Issue:8

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Dexamethasone; Humans; Middle Aged; Multiple Myeloma; Prospective Studies

2023
Bendamustine vs. fludarabine/cyclophosphamide lymphodepletion prior to BCMA CAR-T cell therapy in multiple myeloma.
    Blood cancer journal, 2023, 10-13, Volume: 13, Issue:1

    Topics: B-Cell Maturation Antigen; Bendamustine Hydrochloride; Cell- and Tissue-Based Therapy; Cyclophosphamide; Humans; Immunotherapy, Adoptive; Multiple Myeloma; Receptors, Chimeric Antigen

2023
DCEP and bendamustine/prednisone as salvage therapy for quad- and penta-refractory multiple myeloma.
    Annals of hematology, 2020, Volume: 99, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Cisplatin; Cyclophosphamide; Dexamethasone; Disease-Free Survival; Etoposide; Female; Humans; Male; Middle Aged; Multiple Myeloma; Prednisolone; Retrospective Studies; Salvage Therapy; Survival Rate

2020
Prognostic impact of rapid reduction of involved free light chains in multiple myeloma patients under first-line treatment with Bendamustine, Prednisone, and Bortezomib (BPV).
    Journal of cancer research and clinical oncology, 2021, Volume: 147, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Biomarkers, Tumor; Bortezomib; Female; Humans; Immunoglobulin Light Chains; Male; Middle Aged; Multiple Myeloma; Neoadjuvant Therapy; Predictive Value of Tests; Prednisone; Prognosis; Retrospective Studies; Treatment Outcome

2021
Preclinical anti-myeloma activity of EDO-S101, a new bendamustine-derived molecule with added HDACi activity, through potent DNA damage induction and impairment of DNA repair.
    Journal of hematology & oncology, 2017, 06-20, Volume: 10, Issue:1

    Topics: Animals; Antineoplastic Agents; Apoptosis; Bendamustine Hydrochloride; Benzimidazoles; Cell Cycle Checkpoints; Cell Line, Tumor; DNA Damage; DNA Repair; Histone Deacetylase Inhibitors; Humans; Membrane Potential, Mitochondrial; Mice; Mice, SCID; Mitochondria; Multiple Myeloma

2017
Healthcare resource utilization among patients with relapsed multiple myeloma in the UK, France, and Italy.
    Journal of medical economics, 2018, Volume: 21, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Disease Progression; Female; France; Health Expenditures; Health Resources; Hospitalization; Humans; Italy; Lenalidomide; Male; Middle Aged; Models, Econometric; Multiple Myeloma; Retrospective Studies; Thalidomide; United Kingdom

2018
Bendamustine, pomalidomide, and dexamethasone for relapsed and/or refractory multiple myeloma.
    Blood cancer journal, 2018, 07-31, Volume: 8, Issue:8

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Dexamethasone; Drug Resistance, Neoplasm; Female; Humans; Male; Middle Aged; Multiple Myeloma; Recurrence; Retreatment; Thalidomide; Treatment Outcome

2018
High incidence of reversible renal toxicity of dose-intensified bendamustine-based high-dose chemotherapy in lymphoma and myeloma patients.
    Bone marrow transplantation, 2019, Volume: 54, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Bendamustine Hydrochloride; Female; Humans; Incidence; Kidney; Lymphoma; Male; Multiple Myeloma

2019
[Therapeutic strategies in multiple myeloma: the future role of bendamustine].
    Onkologie, 2013, Volume: 36 Suppl 1

    Topics: Animals; Antineoplastic Agents, Alkylating; Bendamustine Hydrochloride; Dose-Response Relationship, Drug; Forecasting; Humans; Multiple Myeloma; Nitrogen Mustard Compounds

2013
Combination of bendamustine and entinostat synergistically inhibits proliferation of multiple myeloma cells via induction of apoptosis and DNA damage response.
    Cancer letters, 2013, Jul-28, Volume: 335, Issue:2

    Topics: Apoptosis; Bendamustine Hydrochloride; Benzamides; Caspase 3; Caspase 8; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Checkpoint Kinase 2; DNA Damage; DNA Repair; Drug Combinations; Drug Synergism; G2 Phase Cell Cycle Checkpoints; Histone Deacetylase Inhibitors; Histones; Humans; Multiple Myeloma; Nitrogen Mustard Compounds; Poly(ADP-ribose) Polymerases; Protein Serine-Threonine Kinases; Pyridines; S Phase Cell Cycle Checkpoints

2013
United Kingdom Myeloma Forum (UKMF) position statement on the use of bendamustine in myeloma.
    International journal of laboratory hematology, 2014, Volume: 36, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Cell Proliferation; Drug Administration Schedule; Drug Dosage Calculations; Humans; Induction Chemotherapy; Multiple Myeloma; Plasma Cells; Recurrence; Remission Induction

2014
Everolimus enhances the cytotoxicity of bendamustine in multiple myeloma cells through a network of pro-apoptotic and cell-cycle-progression regulatory proteins.
    Acta biochimica et biophysica Sinica, 2013, Volume: 45, Issue:8

    Topics: Antineoplastic Agents; Apoptosis; Bendamustine Hydrochloride; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Everolimus; Humans; Multiple Myeloma; Nitrogen Mustard Compounds; Sirolimus

2013
Activity and toxicity profiles of the combinations bendamustine-lenalidomide-dexamethasone and bendamustine-bortezomib-dexamethasone for advanced stage multiple myeloma.
    Leukemia & lymphoma, 2014, Volume: 55, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Boronic Acids; Bortezomib; Dexamethasone; Humans; Lenalidomide; Multiple Myeloma; Nitrogen Mustard Compounds; Pyrazines; Thalidomide; Treatment Outcome

2014
Bendamustine and prednisone in combination with bortezomib (BPV) in the treatment of patients with relapsed or refractory multiple myeloma and light chain-induced renal failure.
    Journal of cancer research and clinical oncology, 2013, Volume: 139, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Boronic Acids; Bortezomib; Female; Glomerular Filtration Rate; Humans; Immunoglobulin Light Chains; Male; Middle Aged; Multiple Myeloma; Neoplasm Staging; Nitrogen Mustard Compounds; Prednisone; Pyrazines; Renal Insufficiency; Retrospective Studies

2013
Bendamustine and melphalan kill myeloma cells similarly through reactive oxygen species production and activation of the p53 pathway and do not overcome resistance to each other.
    Leukemia & lymphoma, 2014, Volume: 55, Issue:9

    Topics: Bendamustine Hydrochloride; Cell Death; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Synergism; Humans; Melphalan; Multiple Myeloma; Nitrogen Mustard Compounds; Reactive Oxygen Species; Signal Transduction; Tumor Suppressor Protein p53

2014
Bendamustine in combination with high-dose radiotherapy and thalidomide is effective in treatment of multiple myeloma with central nervous system involvement.
    European journal of haematology, 2014, Volume: 92, Issue:5

    Topics: Antineoplastic Agents; Bendamustine Hydrochloride; Central Nervous System; Combined Modality Therapy; Drug Therapy, Combination; Fatal Outcome; Gamma Rays; Humans; Male; Middle Aged; Multiple Myeloma; Nitrogen Mustard Compounds; Thalidomide; Treatment Outcome

2014
Bendamustine: the remedy that came in from the cold.
    Blood, 2014, Feb-13, Volume: 123, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Boronic Acids; Bortezomib; Dexamethasone; Female; Humans; Male; Multiple Myeloma; Nitrogen Mustard Compounds; Pyrazines

2014
Purine analog-like properties of bendamustine underlie rapid activation of DNA damage response and synergistic effects with pyrimidine analogues in lymphoid malignancies.
    PloS one, 2014, Volume: 9, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclophosphamide; Cytarabine; DNA Damage; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Inhibitory Concentration 50; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Multiple Myeloma; Pyrimidines; Rituximab

2014
Bendamustine and prednisone in combination with bortezomib (BPV) in the treatment of patients with newly diagnosed/untreated multiple myeloma.
    Journal of cancer research and clinical oncology, 2014, Volume: 140, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Boronic Acids; Bortezomib; Disease-Free Survival; Female; Glomerular Filtration Rate; Humans; Kaplan-Meier Estimate; Leukopenia; Male; Middle Aged; Multiple Myeloma; Nitrogen Mustard Compounds; Prednisone; Pyrazines; Retrospective Studies; Treatment Outcome

2014
[Hyperammonemic encephalopathy in multiple myeloma].
    Deutsche medizinische Wochenschrift (1946), 2014, Volume: 139, Issue:30

    Topics: Alkalosis, Respiratory; Ammonia; Bendamustine Hydrochloride; Boronic Acids; Bortezomib; Dexamethasone; Drug Therapy, Combination; Dyspnea; Fatal Outcome; Humans; Male; Middle Aged; Multiple Myeloma; Nitrogen Mustard Compounds; Pyrazines; Rett Syndrome

2014
Bortezomib/bendamustine/dexamethasone induced good PR in refractory relapse post auto-SCT with constitutive RAS activation due to V600E BRAF mutation.
    Bone marrow transplantation, 2014, Volume: 49, Issue:12

    Topics: Antineoplastic Agents, Alkylating; Bendamustine Hydrochloride; Boronic Acids; Bortezomib; Dexamethasone; Humans; Immunoglobulin G; Karyotyping; Male; Middle Aged; Multiple Myeloma; Mutation; Nitrogen Mustard Compounds; Proto-Oncogene Proteins B-raf; Pyrazines; ras Proteins; Recurrence; Signal Transduction; Stem Cell Transplantation; Transplantation, Autologous; Treatment Outcome

2014
Bendamustine in combination with thalidomide and dexamethasone is a viable salvage option in myeloma relapsed and/or refractory to bortezomib and lenalidomide.
    Annals of hematology, 2015, Volume: 94, Issue:4

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Boronic Acids; Bortezomib; Dexamethasone; Female; Humans; Lenalidomide; Male; Middle Aged; Multiple Myeloma; Nitrogen Mustard Compounds; Pyrazines; Recurrence; Retrospective Studies; Salvage Therapy; Survival Analysis; Thalidomide; Treatment Failure

2015
The role of bendamustine in the management of plasma cell myeloma.
    Leukemia & lymphoma, 2015, Volume: 56, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Bendamustine Hydrochloride; Female; Humans; Male; Multiple Myeloma

2015
Bendamustine in relapsed/refractory multiple myeloma: the "real-life" side of the moon.
    Leukemia & lymphoma, 2015, Volume: 56, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Female; Humans; Male; Middle Aged; Multiple Myeloma; Neoplasm Staging; Recurrence; Treatment Outcome

2015
Dose-intensified bendamustine followed by autologous peripheral blood stem cell support in relapsed and refractory multiple myeloma with impaired bone marrow function.
    Hematological oncology, 2016, Volume: 34, Issue:4

    Topics: Adult; Aged; Autografts; Bendamustine Hydrochloride; Bone Marrow; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Hematopoiesis; Humans; Male; Middle Aged; Multiple Myeloma; Peripheral Blood Stem Cell Transplantation; Survival Rate; Transplantation Conditioning

2016
Stem cell mobilization and autologous stem cell transplantation after pretreatment with bendamustine, prednisone and bortezomib (BPV) in newly diagnosed multiple myeloma.
    Journal of cancer research and clinical oncology, 2015, Volume: 141, Issue:11

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Blood Component Removal; Bortezomib; Disease-Free Survival; Female; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Humans; Male; Middle Aged; Multiple Myeloma; Prednisone; Retrospective Studies; Transplantation Conditioning; Transplantation, Autologous

2015
Bendamustine in heavily pre-treated patients with relapsed or refractory multiple myeloma.
    Journal of cancer research and clinical oncology, 2015, Volume: 141, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Bendamustine Hydrochloride; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Humans; Male; Middle Aged; Multiple Myeloma; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Retrospective Studies; Salvage Therapy; Survival Rate

2015
Recommendations on the clinical use of bendamustine in lymphoproliferative syndromes and multiple myeloma.
    European journal of haematology, 2016, Volume: 96, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Autoimmune Lymphoproliferative Syndrome; Bendamustine Hydrochloride; Consensus Development Conferences as Topic; Disease Management; Humans; Multiple Myeloma; Practice Guidelines as Topic

2016
New patterns of relapse in multiple myeloma: a case of "light chain escape" in which FLC predicted relapse earlier than urine and serum immunofixation.
    Clinical chemistry and laboratory medicine, 2016, Jun-01, Volume: 54, Issue:6

    Topics: Bence Jones Protein; Bendamustine Hydrochloride; Blood Protein Electrophoresis; Bortezomib; Dexamethasone; Humans; Immunoelectrophoresis; Immunoglobulin G; Immunoglobulin kappa-Chains; Lenalidomide; Male; Middle Aged; Multiple Myeloma; Recurrence; Stem Cell Transplantation; Thalidomide

2016
A single-center retrospective analysis of first-line therapy of multiple myeloma with bendamustine-bortezomib-dexamethasone.
    Leukemia & lymphoma, 2016, Volume: 57, Issue:9

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Biomarkers; Bortezomib; Dexamethasone; Female; Humans; Male; Middle Aged; Multiple Myeloma; Neoplasm Staging; Retrospective Studies; Survival Analysis; Treatment Outcome

2016
Clinical Outcomes Related to the Use of Bendamustine Therapy for Multiple Myeloma Patients Relapsed/Refractory to Immunomodulatory Drugs and Proteasome Inhibitors.
    Turkish journal of haematology : official journal of Turkish Society of Haematology, 2017, Aug-02, Volume: 34, Issue:3

    Topics: Aged; Aged, 80 and over; Bendamustine Hydrochloride; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Humans; Male; Middle Aged; Multiple Myeloma; Proteasome Inhibitors; Recurrence; Retrospective Studies; Survival Rate

2017
Bendamustine in patients with relapsed or refractory multiple myeloma.
    European journal of medical research, 2010, Jan-29, Volume: 15, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Bendamustine Hydrochloride; Disease-Free Survival; Female; Humans; Male; Middle Aged; Multiple Myeloma; Nitrogen Mustard Compounds; Recurrence; Retrospective Studies; Survival Analysis; Treatment Outcome

2010
Reactivation of hepatitis B virus following bendamustine-containing chemotherapy in a patient with multiple myeloma.
    Leukemia & lymphoma, 2011, Volume: 52, Issue:5

    Topics: Antineoplastic Agents; Bendamustine Hydrochloride; Hepatitis B virus; Humans; Male; Middle Aged; Multiple Myeloma; Nitrogen Mustard Compounds; Virus Activation

2011
Efficacy of bendamustine in relapsed/refractory myeloma patients: results from the French compassionate use program.
    Leukemia & lymphoma, 2012, Volume: 53, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Bendamustine Hydrochloride; Cohort Studies; Compassionate Use Trials; Disease-Free Survival; Drug Administration Schedule; Drug Resistance, Neoplasm; Female; France; Humans; Male; Middle Aged; Multiple Myeloma; Nitrogen Mustard Compounds; Recurrence; Time Factors; Treatment Outcome

2012
Bendamustine: inadequate or outdated data.
    Prescrire international, 2012, Volume: 21, Issue:125

    Topics: Antineoplastic Agents, Alkylating; Bendamustine Hydrochloride; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Non-Hodgkin; Multiple Myeloma; Nitrogen Mustard Compounds; Randomized Controlled Trials as Topic

2012
Successful treatment of patients with newly diagnosed/untreated multiple myeloma and advanced renal failure using bortezomib in combination with bendamustine and prednisone.
    Journal of cancer research and clinical oncology, 2012, Volume: 138, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Anemia; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Boronic Acids; Bortezomib; Disease-Free Survival; Drug Administration Schedule; Female; Glomerular Filtration Rate; Humans; Male; Middle Aged; Multiple Myeloma; Nausea; Nitrogen Mustard Compounds; Prednisone; Pyrazines; Renal Insufficiency; Retrospective Studies; Thrombocytopenia; Treatment Outcome; Vomiting

2012
Combined bendamustine, prednisone and bortezomib (BPV) in patients with relapsed or refractory multiple myeloma.
    Journal of cancer research and clinical oncology, 2013, Volume: 139, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Boronic Acids; Bortezomib; Drug Resistance, Neoplasm; Female; Humans; Male; Middle Aged; Multiple Myeloma; Nitrogen Mustard Compounds; Prednisone; Pyrazines; Recurrence; Retrospective Studies

2013
Multiple myeloma, version 1.2013.
    Journal of the National Comprehensive Cancer Network : JNCCN, 2013, Jan-01, Volume: 11, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Boronic Acids; Bortezomib; Dexamethasone; Disease Progression; Humans; Hydroxamic Acids; Lenalidomide; Multiple Myeloma; Nitrogen Mustard Compounds; Oligopeptides; Peripheral Nervous System Diseases; Practice Guidelines as Topic; Pyrazines; Recurrence; Salvage Therapy; Thalidomide; Vorinostat

2013
Bendamustine in the treatment of hematologic malignancies. Introduction.
    Seminars in oncology, 2002, Volume: 29, Issue:4 Suppl 13

    Topics: Antineoplastic Agents; Bendamustine Hydrochloride; Hematologic Neoplasms; Hodgkin Disease; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Non-Hodgkin; Multiple Myeloma; Nitrogen Mustard Compounds

2002
The efficacy and toxicity of bendamustine in recurrent multiple myeloma after high-dose chemotherapy.
    Haematologica, 2005, Volume: 90, Issue:9

    Topics: Adult; Aged; Antineoplastic Agents; Bendamustine Hydrochloride; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Multiple Myeloma; Neoplasm Recurrence, Local; Nitrogen Mustard Compounds

2005
Bendamustine induces G2 cell cycle arrest and apoptosis in myeloma cells: the role of ATM-Chk2-Cdc25A and ATM-p53-p21-pathways.
    Journal of cancer research and clinical oncology, 2008, Volume: 134, Issue:2

    Topics: Apoptosis; Ataxia Telangiectasia Mutated Proteins; Bendamustine Hydrochloride; Blotting, Western; cdc25 Phosphatases; Cell Cycle Proteins; Cell Proliferation; Checkpoint Kinase 2; Cyclin-Dependent Kinase Inhibitor p21; DNA-Binding Proteins; Flow Cytometry; G2 Phase; Humans; Multiple Myeloma; Nitrogen Mustard Compounds; Phosphorylation; Protein Serine-Threonine Kinases; Signal Transduction; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Tyrosine

2008
What is the correct philosophy for the treatment of multiple myeloma?
    Leukemia & lymphoma, 2007, Volume: 48, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Boronic Acids; Bortezomib; Dexamethasone; Humans; Multiple Myeloma; Nitrogen Mustard Compounds; Pyrazines

2007
Escalation therapy with bortezomib, dexamethasone and bendamustine for patients with relapsed or refractory multiple myeloma.
    Leukemia & lymphoma, 2007, Volume: 48, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Boronic Acids; Bortezomib; Dexamethasone; Disease Progression; Female; Humans; Male; Middle Aged; Multiple Myeloma; Nitrogen Mustard Compounds; Pyrazines; Salvage Therapy

2007