bemethyl and Somatoform-Disorders

bemethyl has been researched along with Somatoform-Disorders* in 1 studies

Other Studies

1 other study(ies) available for bemethyl and Somatoform-Disorders

Article	Year
[Pharmacokinetics of domestic actoprotector drug Metaprot in healthy volunteers]. Eksperimental'naia i klinicheskaia farmakologiia, 2011, Volume: 74, Issue:6 Pharmacokinetics of the actoprotector Metaprot, an original Russian drug, has been studied in a group of healthy adult volunteers. Metaprot in capsules was administrated orally as a single dose of 250 mg. The concentration of the active substance (ethylthiobenzimidazole) in the blood serum was determined by high-performance liquid chromatography (HPLC) with UV detection. The pharmacokinetic parameters were calculated by the model-independent method. The peak concentration of ethylthiobenzimidazole in plasma was Cmax = 0.91 +/- 1.05 microg/ml and the average time to peak concentration was t(max) = 1.06 +/- 0.16 h. A polymodal character of the distribution of pharmacokinetic parameters in the test group was revealed. Topics: Administration, Oral; Adult; Area Under Curve; Benzimidazoles; Cerebrovascular Disorders; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Female; Humans; Male; Russia; Somatoform Disorders; Young Adult	2011

Article

Year

[Pharmacokinetics of domestic actoprotector drug Metaprot in healthy volunteers].

Eksperimental'naia i klinicheskaia farmakologiia, 2011, Volume: 74, Issue:6

Pharmacokinetics of the actoprotector Metaprot, an original Russian drug, has been studied in a group of healthy adult volunteers. Metaprot in capsules was administrated orally as a single dose of 250 mg. The concentration of the active substance (ethylthiobenzimidazole) in the blood serum was determined by high-performance liquid chromatography (HPLC) with UV detection. The pharmacokinetic parameters were calculated by the model-independent method. The peak concentration of ethylthiobenzimidazole in plasma was Cmax = 0.91 +/- 1.05 microg/ml and the average time to peak concentration was t(max) = 1.06 +/- 0.16 h. A polymodal character of the distribution of pharmacokinetic parameters in the test group was revealed.

Topics: Administration, Oral; Adult; Area Under Curve; Benzimidazoles; Cerebrovascular Disorders; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Female; Humans; Male; Russia; Somatoform Disorders; Young Adult

2011