bemethyl has been researched along with Craniocerebral-Trauma* in 2 studies
2 other study(ies) available for bemethyl and Craniocerebral-Trauma
| Article | Year |
|---|---|
Cerebroprotective effect of combined treatment with pyrazidol and bemitil in craniocerebral trauma.
Monotherapy of consequences of craniocerebral trauma with pyrazidol (1 mg/kg) produced an anxiolytic effect in animals highly resistant to hypoxia and activating effect on low resistant animals. Treatment with bemitil in a dose of 25 mg/kg produced a cerebroprotective effect and normalized individual behavioral characteristics, parameters of energy metabolism, and state of the antioxidant system in the brain of highly and low resistant rats. The effect of bemitil was most pronounced in highly resistant animals. During combined treatment, pyrazidol and bemitil had an additive effect in animals of both groups. They normalized behavioral reactions and prevented the development of metabolic disturbances in the brain. Topics: Animals; Animals, Outbred Strains; Antioxidants; Behavior, Animal; Benzimidazoles; Carbazoles; Craniocerebral Trauma; Drug Synergism; Drug Therapy, Combination; Energy Metabolism; Hypoxia; Lipid Peroxidation; Male; Neuroprotective Agents; Rats | 2004 |
Drug correction of behavioral reactions and metabolic disorders in rats with craniocerebral trauma.
Intraperitoneal injection of bemithyl in a dose of 25 mg/kg for 3 days after craniocerebral injury reduced psychopathological symptoms in rats with different resistance to acute hypoxia, restored the structure of individual behavior, and prevented metabolic disorders in the brain. Topics: Animals; Antioxidants; Benzimidazoles; Body Weight; Brain; Brain Injuries; Carbon Tetrachloride Poisoning; Craniocerebral Trauma; Disease Models, Animal; Hypoxia; Injections, Intraperitoneal; Male; Metabolic Diseases; Neuroprotective Agents; Piracetam; Rats; Temperature; Time Factors | 2003 |