Page last updated: 2024-08-26

becatecarin and Neoplasms

becatecarin has been researched along with Neoplasms in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (87.50)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bokar, JA; Brell, JM; Cooney, MM; Cooper, B; Dowlati, A; Gibbons, J; Ivy, P; Krishnamurthi, S; Manda, S; Nock, CJ; Remick, SC; Savvides, P1
Alberti, D; Arzoomanian, R; Binger, K; Cleary, J; Dresen, A; Feierabend, C; Marnoccha, R; Merchant, J; Thomas, J; Tutsch, K; Wilding, G1
Forenza, S; Long, BH; Matson, JA; Rose, WC; Vyas, DM1
Baruchel, S; Bernstein, M; Blaney, S; Furman, W; Kuhn, JG; Langevin, AM; Vietti, T; Weintraub, ST; Weitman, SD1
Berg, K; Forero, L; Forouzesh, B; Goetz, A; Hammond, LA; Kuhn, JG; Ochoa-Bayona, JL; Ricart, AD; Rowinsky, EK; Takimoto, CH; Tolcher, AW1
Adamson, PC; Bernstein, M; Blaney, SM; Chen, Z; Ivy, P; Kuhn, JG; Langevin, AM; Sun, J1
Dowlati, A; Gerson, SL; Hoppel, CL; Ingalls, ST; Ivy, P; Li, X; Majka, S; Remick, SC; Sedransk, N; Spiro, T1
Aylesworth, C; Campbell, E; Eckhardt, SG; Felton, S; Hammond, L; Hidalgo, M; Kuhn, J; Patnaik, A; Rizzo, J; Rowinsky, EK; Schwartz, G; Tolcher, AW; Weiss, G1

Reviews

1 review(s) available for becatecarin and Neoplasms

ArticleYear
Discovery of antitumor indolocarbazoles: rebeccamycin, NSC 655649, and fluoroindolocarbazoles.
    Current medicinal chemistry. Anti-cancer agents, 2002, Volume: 2, Issue:2

    Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Carbazoles; Drug Design; Glucosides; Humans; Indoles; Neoplasms; Structure-Activity Relationship

2002

Trials

7 trial(s) available for becatecarin and Neoplasms

ArticleYear
A phase I study of rebeccamycin analog in combination with oxaliplatin in patients with refractory solid tumors.
    Investigational new drugs, 2011, Volume: 29, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carbazoles; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Glucosides; Humans; Male; Middle Aged; Neoplasms; Organoplatinum Compounds; Oxaliplatin

2011
Phase I clinical and pharmacokinetic study of NSC 655649, a rebeccamycin analogue, given in both single-dose and multiple-dose formats.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2002, Volume: 8, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Aminoglycosides; Anti-Bacterial Agents; Antineoplastic Agents; Carbazoles; Dose-Response Relationship, Drug; Female; Gastrointestinal Diseases; Glucosides; Humans; Infusions, Intravenous; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms; Neutropenia; Thrombocytopenia

2002
Phase I trial of rebeccamycin analog (NSC #655649) in children with refractory solid tumors: a pediatric oncology group study.
    Journal of pediatric hematology/oncology, 2003, Volume: 25, Issue:7

    Topics: Adolescent; Aminoglycosides; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Area Under Curve; Carbazoles; Child; Child, Preschool; Drug Administration Schedule; Glucosides; Hemoglobins; Humans; Infant; Metabolic Clearance Rate; Neoplasms; Neutropenia; Patient Selection; Platelet Count

2003
Phase I and pharmacokinetic study of sequences of the rebeccamycin analogue NSC 655649 and cisplatin in patients with advanced solid tumors.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Dec-15, Volume: 11, Issue:24 Pt 1

    Topics: Adult; Aged; Aged, 80 and over; Aminoglycosides; Antineoplastic Combined Chemotherapy Protocols; Carbazoles; Cisplatin; Drug Interactions; Female; Glucosides; Humans; Male; Middle Aged; Neoplasms; Neutropenia; Thrombocytopenia; Tomography, X-Ray Computed

2005
A phase II trial of rebeccamycin analogue (NSC #655649) in children with solid tumors: a Children's Oncology Group study.
    Pediatric blood & cancer, 2008, Volume: 50, Issue:3

    Topics: Adolescent; Adult; Aminoglycosides; Antibiotics, Antineoplastic; Bone Marrow Diseases; Carbazoles; Central Nervous System Neoplasms; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Female; Glucosides; Humans; Infant; Infant, Newborn; Infusions, Intravenous; Male; Neoplasm Proteins; Neoplasms; Pancreatitis; Rhabdomyosarcoma; Salvage Therapy; Topoisomerase II Inhibitors

2008
Phase I clinical and pharmacokinetic study of rebeccamycin analog NSC 655649 given daily for five consecutive days.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2001, Apr-15, Volume: 19, Issue:8

    Topics: Adult; Aged; Aminoglycosides; Anti-Bacterial Agents; Antineoplastic Agents; Carbazoles; Cholangiocarcinoma; Disease Progression; Dose-Response Relationship, Drug; Female; Gallbladder Neoplasms; Glucosides; Humans; Infusions, Intravenous; Liver Neoplasms; Male; Middle Aged; Neoplasms; Neutropenia

2001
Phase I and pharmacokinetic study of NSC 655649, a rebeccamycin analog with topoisomerase inhibitory properties.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2001, Jun-01, Volume: 19, Issue:11

    Topics: Adult; Aged; Aminoglycosides; Anti-Bacterial Agents; Antineoplastic Agents; Carbazoles; Dose-Response Relationship, Drug; Female; Glucosides; Humans; Infusions, Intravenous; Male; Middle Aged; Neoplasms; Neutropenia; Thrombocytopenia

2001