Page last updated: 2024-09-05

bd 1047 and Allodynia

bd 1047 has been researched along with Allodynia in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (8.33)29.6817
2010's10 (83.33)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Chun, S; Kwon, YB; Lee, JH; Yoon, SY1
Beitz, AJ; Choi, HS; Choi, SR; Han, HJ; Kang, SY; Kwon, SG; Lee, JH; Moon, JY; Oh, SB; Roh, DH; Yoon, SY1
Beitz, AJ; Choi, HS; Choi, SR; Han, HJ; Kang, SY; Kim, HW; Kwon, SG; Lee, JH; Moon, JY; Oh, SB; Roh, DH; Yoon, SY2
Jeong, YC; Kwon, YB; Son, JS1
Han, Y; Hu, X; Liu, Y; Song, C; Wang, C; Zhu, S1
Beitz, AJ; Choi, HS; Choi, SR; Kang, SY; Kwon, SG; Lee, JH; Moon, JY; Roh, DH; Yoon, SY1
Beitz, AJ; Choi, HS; Choi, SR; Han, HJ; Kwon, SG; Lee, JH; Roh, DH; Yoon, SY1
Choi, JG; Kang, DW; Kang, SY; Kim, HW; Lee, JH; Moon, JY; Park, JB; Ryu, Y1
Beitz, AJ; Choi, HS; Choi, SR; Han, HJ; Kang, SY; Kwon, SG; Lee, JH; Moon, JY; Roh, DH; Yoon, SY2
Baeyens, JM; Cendán, CM; Cobos, EJ; Del Pozo, E; Entrena, JM; Gris, G; Nieto, FR; Zamanillo, D1

Other Studies

12 other study(ies) available for bd 1047 and Allodynia

ArticleYear
The Peripheral Role of CCL2 in the Anti-Nociceptive Effect of Sigma-1 Receptor Antagonist BD1047 on Inflammatory Hyperalgesia in Rats.
    International journal of molecular sciences, 2021, Oct-29, Volume: 22, Issue:21

    Topics: Analgesics; Animals; Cells, Cultured; Chemokine CCL2; Ethylenediamines; Hyperalgesia; Inflammation; Male; Rats; Rats, Sprague-Dawley; Receptors, sigma; Sigma-1 Receptor

2021
Spinal sigma-1 receptors activate NADPH oxidase 2 leading to the induction of pain hypersensitivity in mice and mechanical allodynia in neuropathic rats.
    Pharmacological research, 2013, Volume: 74

    Topics: Animals; Ethylenediamines; Hot Temperature; Hyperalgesia; Male; Membrane Glycoproteins; Mice; Mice, Inbred ICR; Morpholines; NADPH Oxidase 2; NADPH Oxidases; Neuralgia; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, sigma; Sigma-1 Receptor; Spinal Cord; Touch

2013
Spinal sigma-1 receptor activation increases the production of D-serine in astrocytes which contributes to the development of mechanical allodynia in a mouse model of neuropathic pain.
    Pharmacological research, 2015, Volume: 100

    Topics: Animals; Astrocytes; Disease Models, Animal; Ethylenediamines; Hyperalgesia; Male; Mice; Mice, Inbred ICR; Neuralgia; Posterior Horn Cells; Racemases and Epimerases; Receptors, sigma; Serine; Sigma-1 Receptor; Spinal Cord

2015
Role of peripheral sigma-1 receptors in ischaemic pain: Potential interactions with ASIC and P2X receptors.
    European journal of pain (London, England), 2016, Volume: 20, Issue:4

    Topics: Acid Sensing Ion Channels; Adenosine Triphosphate; Animals; Ethylenediamines; Hindlimb; Hyperalgesia; Ischemia; Male; Morpholines; Pain; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2X; Receptors, sigma; Sigma-1 Receptor

2016
The spinal antinociceptive mechanism determined by systemic administration of BD1047 in zymosan-induced hyperalgesia in rats.
    Brain research bulletin, 2015, Volume: 119, Issue:Pt A

    Topics: Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Ethylenediamines; Hyperalgesia; Male; Microglia; Pain; Posterior Horn Cells; Rats, Sprague-Dawley; Receptors, sigma; Spinal Cord; Zymosan

2015
Sigma-1 Receptor Antagonist BD1047 Reduces Mechanical Allodynia in a Rat Model of Bone Cancer Pain through the Inhibition of Spinal NR1 Phosphorylation and Microglia Activation.
    Mediators of inflammation, 2015, Volume: 2015

    Topics: Animals; Bone Neoplasms; Disease Models, Animal; Ethylenediamines; Extracellular Signal-Regulated MAP Kinases; Female; Hyperalgesia; Microglia; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Sigma-1 Receptor; Spinal Cord

2015
Peripheral neurosteroids enhance P2X receptor-induced mechanical allodynia via a sigma-1 receptor-mediated mechanism.
    Brain research bulletin, 2016, Volume: 121

    Topics: Adenosine Triphosphate; Animals; Dehydroepiandrosterone Sulfate; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Ethylenediamines; Hyperalgesia; Male; Pain Measurement; Pregnenolone; Purinergic P2X Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2X; Receptors, sigma; Time Factors

2016
Astrocyte sigma-1 receptors modulate connexin 43 expression leading to the induction of below-level mechanical allodynia in spinal cord injured mice.
    Neuropharmacology, 2016, Volume: 111

    Topics: Animals; Astrocytes; Connexin 43; Disease Models, Animal; Ethylenediamines; Hyperalgesia; Male; Mice; Mice, Inbred ICR; Neuralgia; Receptors, sigma; Sigma-1 Receptor; Spinal Cord Dorsal Horn; Spinal Cord Injuries

2016
Antinociceptive Profile of Levo-tetrahydropalmatine in Acute and Chronic Pain Mice Models: Role of spinal sigma-1 receptor.
    Scientific reports, 2016, 12-02, Volume: 6

    Topics: Analgesics; Animals; Berberine Alkaloids; Chronic Pain; Ethylenediamines; Formaldehyde; Gene Expression Regulation; Hyperalgesia; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Naloxone; Neuralgia; Pain Management; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Receptors, sigma; Sigma-1 Receptor; Spinal Cord

2016
Spinal D-Serine Increases PKC-Dependent GluN1 Phosphorylation Contributing to the Sigma-1 Receptor-Induced Development of Mechanical Allodynia in a Mouse Model of Neuropathic Pain.
    The journal of pain, 2017, Volume: 18, Issue:4

    Topics: Animals; D-Amino-Acid Oxidase; Disease Models, Animal; Enzyme Inhibitors; Ethylenediamines; Excitatory Amino Acid Agonists; Gene Expression Regulation; Hyperalgesia; Male; Mice; Mice, Inbred ICR; Morpholines; N-Methylaspartate; Nerve Tissue Proteins; Neuralgia; Phosphorylation; Physical Stimulation; Protein Kinase C; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Serine; Sigma-1 Receptor; Spinal Cord

2017
Sigma-1 receptors are essential for capsaicin-induced mechanical hypersensitivity: studies with selective sigma-1 ligands and sigma-1 knockout mice.
    Pain, 2009, Volume: 143, Issue:3

    Topics: Animals; Anisoles; Capsaicin; DNA; Ethylenediamines; Female; Hyperalgesia; Mice; Mice, Knockout; Morpholines; Nociceptors; Pain Measurement; Pain Threshold; Physical Stimulation; Piperazines; Polymerase Chain Reaction; Propylamines; Reaction Time; Receptors, sigma; Sensory Receptor Cells; Sensory System Agents; Sigma-1 Receptor; Spinal Cord

2009
Sigma-1 receptor-mediated increase in spinal p38 MAPK phosphorylation leads to the induction of mechanical allodynia in mice and neuropathic rats.
    Experimental neurology, 2013, Volume: 247

    Topics: Analysis of Variance; Animals; Disease Models, Animal; Enzyme Inhibitors; Ethylenediamines; Hyperalgesia; Imidazoles; Male; Mice; Mice, Inbred ICR; Morpholines; p38 Mitogen-Activated Protein Kinases; Pain Measurement; Pain Threshold; Phosphorylation; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, sigma; Sciatica; Sigma-1 Receptor; Spinal Cord

2013