Page last updated: 2024-09-04

bcx 1812 and Infections, Orthomyxoviridae

bcx 1812 has been researched along with Infections, Orthomyxoviridae in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ananth, SL; Babu, YS; Bantia, S; Chand, P; Dehghani, A; El-Kattan, Y; Elliott, AJ; Horn, LL; Hutchison, TL; Kotian, P; Laver, GW; Lin, TH; Montgomery, JA; Parker, CD1
Barr, IG; Holien, JK; Hurt, AC1
Abed, Y; Boivin, G; Simon, P1

Other Studies

3 other study(ies) available for bcx 1812 and Infections, Orthomyxoviridae

ArticleYear
BCX-1812 (RWJ-270201): discovery of a novel, highly potent, orally active, and selective influenza neuraminidase inhibitor through structure-based drug design.
    Journal of medicinal chemistry, 2000, Sep-21, Volume: 43, Issue:19

    Topics: Acids, Carbocyclic; Administration, Oral; Animals; Antiviral Agents; Catalytic Domain; Crystallography, X-Ray; Cyclopentanes; Drug Design; Enzyme Inhibitors; Guanidines; Influenza A virus; Influenza B virus; Mice; Models, Molecular; Neuraminidase; Orthomyxoviridae Infections; Protein Binding; Stereoisomerism; Structure-Activity Relationship

2000
In vitro generation of neuraminidase inhibitor resistance in A(H5N1) influenza viruses.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:10

    Topics: Animals; Antiviral Agents; Cell Line; Dogs; Influenza A Virus, H5N1 Subtype; Mutagenesis, Site-Directed; Mutation; Neuraminidase; Orthomyxoviridae Infections; Reverse Transcriptase Polymerase Chain Reaction

2009
Prophylactic activity of intramuscular peramivir in mice infected with a recombinant influenza A/WSN/33 (H1N1) virus containing the H274Y neuraminidase mutation.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:7

    Topics: Acids, Carbocyclic; Animals; Antiviral Agents; Cell Line; Cyclopentanes; Dogs; Guanidines; Influenza A Virus, H1N1 Subtype; Injections, Intramuscular; Male; Mice; Mice, Inbred BALB C; Mutation; Neuraminidase; Orthomyxoviridae Infections; Viral Proteins

2010