Page last updated: 2024-09-04

bazedoxifene and Disease Models, Animal

bazedoxifene has been researched along with Disease Models, Animal in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's10 (71.43)24.3611
2020's4 (28.57)2.80

Authors

AuthorsStudies
Lin, J; Reader, J; Roque, DM; Zhang, R1
Guo, J; Huo, S; Li, C; Li, S; Lin, J; Lin, L; Liu, T; Luo, P; Lv, J; Ma, H; Shi, W; Tao, J; Yan, D; Zhai, M; Zhang, C1
Guo, J; Huo, S; Li, C; Li, S; Lin, J; Lin, L; Liu, T; Luo, P; Lv, J; Ma, H; Shi, W; Wang, M; Wang, Y; Yan, D; Zhang, C; Zhao, C1
Cho, JH; Chu, J; Chuang, LS; Gettler, K; Giri, M; Kenigsberg, E; Ko, HM; Kugathasan, S; Merad, M; Morrison, JK; Nayar, S; Walker, LA1
Hashimoto, T; Kitazato, KT; Korai, M; Maekawa, H; Miyamoto, T; Nagahiro, S; Satomi, J; Tada, Y; Yagi, K1
Bossen, J; Bruchhaus, I; Burkhardt, L; Fink, C; Heine, H; Mai, MM; Pfefferkorn, R; Roeder, T; Spohn, M; Steen, L; Uliczka, K1
Komm, B; Krikun, G; Naqvi, H; Presti, T; Sakr, S; Taylor, HS1
Chen, H; Chen, R; Dang, Q; Liu, Y; Lyu, H1
Lovre, D; Mauvais-Jarvis, F; Xu, B1
Arakawa, S; Kida, Y; Marumo, K; Nishizawa, T; Okabe, H; Saito, M; Seki, A1
Andersson, A; Bernardi, AI; Carlsten, H; Islander, U; Nurkkala-Karlsson, M; Ohlsson, C; Stubelius, A1
Cao, Y; Li, C; Lin, J; Wu, X; Xiao, H1
Fischer, C; Komm, B; Kulak, J; Taylor, HS1
Gordon, IO; Greene, GL; Krausz, TN; Lee, W; Lengyel, E; Leonhardt, P; Mitra, AK; Mui, KL; Penicka, CV; Romero, IL; Zhao, Y1

Reviews

1 review(s) available for bazedoxifene and Disease Models, Animal

ArticleYear
Effect of selective estrogen receptor modulators on metabolic homeostasis.
    Biochimie, 2016, Volume: 124

    Topics: Animals; Breast; Breast Neoplasms; Diabetes Mellitus, Type 2; Disease Models, Animal; Estrogens; Female; Humans; Indoles; Metabolic Syndrome; Osteoporosis, Postmenopausal; Receptors, Estrogen; Uterus

2016

Other Studies

13 other study(ies) available for bazedoxifene and Disease Models, Animal

ArticleYear
Combined inhibition of IL‑6 and IL‑8 pathways suppresses ovarian cancer cell viability and migration and tumor growth.
    International journal of oncology, 2022, Volume: 60, Issue:5

    Topics: Animals; Benzamides; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cyclobutanes; Disease Models, Animal; Drug Therapy, Combination; Female; Humans; Indoles; Interleukin-6; Interleukin-8; Mice; Ovarian Neoplasms; Selective Estrogen Receptor Modulators

2022
Inhibition of Interleukin-6/glycoprotein 130 signalling by Bazedoxifene ameliorates cardiac remodelling in pressure overload mice.
    Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:8

    Topics: Animals; Autophagy; Cytokine Receptor gp130; Disease Models, Animal; Gene Expression Regulation; Heart; Humans; Hypertension; Indoles; Interleukin-6; Mice; Rats; STAT3 Transcription Factor; Ventricular Remodeling

2020
Bazedoxifene exhibits anti-inflammation and anti-atherosclerotic effects via inhibition of IL-6/IL-6R/STAT3 signaling.
    European journal of pharmacology, 2021, Feb-15, Volume: 893

    Topics: Animals; Anti-Inflammatory Agents; Aorta; Atherosclerosis; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Human Umbilical Vein Endothelial Cells; Humans; Indoles; Interleukin-6; Male; Mice, Knockout, ApoE; Muscle, Smooth, Vascular; Phosphorylation; Plaque, Atherosclerotic; Rats; Receptors, Interleukin-6; Signal Transduction; STAT3 Transcription Factor

2021
A myeloid-stromal niche and gp130 rescue in NOD2-driven Crohn's disease.
    Nature, 2021, Volume: 593, Issue:7858

    Topics: Alleles; Animals; Collagen; Crohn Disease; Cytokine Receptor gp130; Disease Models, Animal; Female; Fibroblasts; Humans; Ileitis; Indoles; Interleukin-11; Lipopolysaccharide Receptors; Macrophages; Male; Myeloid Cells; Nod2 Signaling Adaptor Protein; Receptor, Platelet-Derived Growth Factor alpha; STAT3 Transcription Factor; Stromal Cells; WT1 Proteins; Zebrafish; Zebrafish Proteins

2021
Bazedoxifene, a selective estrogen receptor modulator, reduces cerebral aneurysm rupture in Ovariectomized rats.
    Journal of neuroinflammation, 2017, Oct-02, Volume: 14, Issue:1

    Topics: Animals; Blood Pressure; Cerebral Arteries; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Gene Expression Regulation; Hypertension; Indoles; Intracranial Aneurysm; Matrix Metalloproteinase 2; Ovariectomy; Rats; Rats, Sprague-Dawley; RNA, Messenger; Salts; Selective Estrogen Receptor Modulators; Tissue Inhibitor of Metalloproteinase-2

2017
An EGFR-Induced
    Molecular cancer therapeutics, 2019, Volume: 18, Issue:9

    Topics: Animals; Animals, Genetically Modified; Carcinoma, Non-Small-Cell Lung; Disease Models, Animal; Drosophila melanogaster; Drosophila Proteins; Drug Synergism; ErbB Receptors; Gene Expression Profiling; Humans; Indoles; Lung Neoplasms; Mutation; Protein Kinase Inhibitors; Trachea

2019
Treatment with bazedoxifene and conjugated estrogens results in regression of endometriosis in a murine model.
    Biology of reproduction, 2014, Volume: 90, Issue:6

    Topics: Animals; Cell Proliferation; Disease Models, Animal; Endometriosis; Estrogen Receptor alpha; Estrogens, Conjugated (USP); Female; Humans; Indoles; Mice, Inbred Strains; Organ Size; Ovarian Follicle; Random Allocation; Receptors, Progesterone; Selective Estrogen Receptor Modulators; Treatment Outcome

2014
[Effect of bazedoxifene on endometriosis in a rat model].
    Zhonghua fu chan ke za zhi, 2015, Volume: 50, Issue:4

    Topics: Animals; Disease Models, Animal; Endometriosis; Endometrium; Female; Humans; Immunohistochemistry; Indoles; Proliferating Cell Nuclear Antigen; Rats; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Uterus

2015
Effects of 18-month treatment with bazedoxifene on enzymatic immature and mature cross-links and non-enzymatic advanced glycation end products, mineralization, and trabecular microarchitecture of vertebra in ovariectomized monkeys.
    Bone, 2015, Volume: 81

    Topics: Animals; Arginine; Bone Density; Bone Density Conservation Agents; Collagen; Cross-Linking Reagents; Disease Models, Animal; Female; Glycation End Products, Advanced; Humans; Indoles; Lumbar Vertebrae; Lysine; Macaca fascicularis; Osteoporosis, Postmenopausal; Ovariectomy; Selective Estrogen Receptor Modulators; X-Ray Microtomography

2015
Selective oestrogen receptor modulators lasofoxifene and bazedoxifene inhibit joint inflammation and osteoporosis in ovariectomised mice with collagen-induced arthritis.
    Rheumatology (Oxford, England), 2016, Volume: 55, Issue:3

    Topics: Animals; Area Under Curve; Arthritis, Experimental; Biomarkers; Collagen; Disease Models, Animal; Female; Flow Cytometry; Humans; Indoles; Interleukin-6; Mice; Mice, Inbred DBA; Osteoarthritis; Osteoporosis, Postmenopausal; Ovariectomy; Pyrrolidines; Random Allocation; Selective Estrogen Receptor Modulators; Tetrahydronaphthalenes; Treatment Outcome

2016
Bazedoxifene as a Novel GP130 Inhibitor for Pancreatic Cancer Therapy.
    Molecular cancer therapeutics, 2016, Volume: 15, Issue:11

    Topics: Animals; Antineoplastic Agents; Apoptosis; Bone Density Conservation Agents; Cell Line, Tumor; Cell Survival; Cytokine Receptor gp130; Cytokines; Disease Models, Animal; Female; Humans; Indoles; Mice; Models, Molecular; Molecular Conformation; Pancreatic Neoplasms; Phosphorylation; Protein Binding; Selective Estrogen Receptor Modulators; Signal Transduction; STAT Transcription Factors; Xenograft Model Antitumor Assays

2016
Treatment with bazedoxifene, a selective estrogen receptor modulator, causes regression of endometriosis in a mouse model.
    Endocrinology, 2011, Volume: 152, Issue:8

    Topics: Animals; Caspase 3; Disease Models, Animal; Endometriosis; Female; Indoles; Mice; Proliferating Cell Nuclear Antigen; Receptors, Estrogen; Selective Estrogen Receptor Modulators

2011
The effects of 17β-estradiol and a selective estrogen receptor modulator, bazedoxifene, on ovarian carcinogenesis.
    Gynecologic oncology, 2012, Volume: 124, Issue:1

    Topics: Animals; Cell Growth Processes; Cell Line, Tumor; Cell Transformation, Neoplastic; Disease Models, Animal; Drug Interactions; Estradiol; Estrogen Antagonists; Female; Genetic Predisposition to Disease; Indoles; Mice; Mice, Transgenic; Neoplasm Invasiveness; Ovarian Neoplasms; Ovary; Selective Estrogen Receptor Modulators

2012