bazedoxifene has been researched along with Breast Cancer in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (6.25) | 29.6817 |
| 2010's | 26 (81.25) | 24.3611 |
| 2020's | 4 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, H; Dubrovyskyii, O; Dye, K; Gordon-Blake, J; Gutgesell, LM; He, D; Hollas, M; Huang, F; Lasek, AW; Lee, S; Li, Y; Lu, Y; Rosales, CI; Shen, Z; Thatcher, GRJ; Tonetti, DA; Wang, Y; Xiong, R; Zhao, H; Zhao, J | 1 |
| Anderson, L; Cibulskis, C; Coorens, T; Getz, G; Grinshpun, A; Jeselsohn, R; Krop, IE; Lennon, NJ; Leshchiner, I; Li, T; McDonnell, DP; Nardone, A; Patterson, C; Rees, R; Russo, D; Stewart, C; Tayob, N; Tolaney, SM; Tsuji, J; Tung, N; Winer, EP | 1 |
| Beachler, DC; Dai, D; Daniels, K; Fournakis, N; Frajzyngier, V; Garg, RK; Governor, S; Hoffman, SR; Lanes, S; Mcmahill-Walraven, CN; Seals, RM; Shen, R; Shuminski, P; Wang, FT; Zhou, X; Ziyadeh, NJ | 1 |
| Chalise, P; Fabian, CJ; Gajewski, BJ; Goodman, ML; Hagan, CR; Kimler, BF; Koestler, DC; Kreutzjans, AL; Metheny, T; Nydegger, JL; Nye, L; Phillips, TA; Powers, KR; Winblad, O; Zalles, CM | 1 |
| Arnautova, YA; Arora, S; Chan, B; Clark, MA; Cuozzo, JW; Disch, JS; Duffy, JM; Gikunju, D; Huguet, C; Keefe, AD; Kohlmann, A; Kozhushnyan, A; Lau, AC; Lee, ECY; Levin, B; Liu, Y; McRiner, AJ; Monteiro, MI; Mullins, PB; Talcott, SA; von Rechenberg, M; Westlund, NE; Yu, Y; Zhang, J; Zhang, Y; Zhou, F | 1 |
| Jeselsohn, RM | 1 |
| Boucher, M; Morgenstern, D; Pickar, JH | 1 |
| Liu, J; VAN Heertum, K | 1 |
| Brown, M; Buchwalter, G; Carlson, KE; Chandarlapaty, S; Dharmarajan, V; Fanning, SW; Fowler, CE; Greene, GL; Griffin, PR; Han, R; Hosfield, DJ; Houtman, R; Jeselsohn, R; Karimi, M; Katzenellenbogen, JA; Lainé, M; Martin, TA; Mayne, CG; Nettles, KW; Nowak, J; Nwachukwu, JC; Shen, Y; Tajkhorshid, E; Toy, W | 1 |
| Conner, EA; Pinkerton, JV | 1 |
| Chao, CA; McDonnell, DP; Nelson, ER; Wardell, SE | 1 |
| Pinkerton, JV; Thomas, S | 1 |
| Jordan, VC | 1 |
| Lovre, D; Mauvais-Jarvis, F; Xu, B | 1 |
| Arnal, JF; Gourdy, P; Trémollières, F; Valera, MC | 1 |
| Komm, BS; Pickar, JH | 1 |
| Santen, RJ; Song, Y; Wang, JP; Yue, W | 2 |
| Gillespie, JA; Parish, SJ | 1 |
| Bodine, PV; Chang, KC; Komm, BS; Nagpal, S; Wang, Y | 1 |
| Silverman, SL | 1 |
| Schmidt, C | 1 |
| Archer, DF | 1 |
| Curpan, R; Grigg, R; Jordan, VC; Kim, H; Lewis-Wambi, JS; Sarker, MA | 1 |
| Jenwitheesuk, E; Puchadapirom, P; Suthiyotha, N; Toniti, W | 1 |
| Hadji, P | 1 |
| Appt, SE; Clarkson, TB; Cline, JM; Ethun, KF; Register, TC; Wood, CE | 1 |
| Baracat, EC; Chines, AA; Harvey, JA; Mirkin, S; Pinkerton, JV; Shi, H | 1 |
| Calaf Alsina, J; Coronado Martín, PJ | 1 |
| Sayegh, RA | 1 |
| Bodine, PV; Harris, HA; Kharode, YP; Komm, BS; Lyttle, CR; Miller, CP | 1 |
| Chaki, O | 1 |
13 review(s) available for bazedoxifene and Breast Cancer
| Article | Year |
|---|---|
Tissue selective estrogen complex (TSEC): a review.
Topics: Bone Density; Breast Neoplasms; Drug Synergism; Drug Therapy, Combination; Endometrium; Estrogens; Estrogens, Conjugated (USP); Female; Hormone Replacement Therapy; Humans; Indoles; Menopause; Osteoporosis, Postmenopausal; Selective Estrogen Receptor Modulators | 2018 |
Differential Effects of Progestogens Used for Menopausal Hormone Therapy.
Topics: Breast Neoplasms; Carbohydrate Metabolism; Cardiovascular Diseases; Carotid Intima-Media Thickness; Female; Hormone Replacement Therapy; Humans; Indoles; Lipids; Menopause; Progestins; Selective Estrogen Receptor Modulators; Stroke; Thromboembolism | 2018 |
Beyond estrogen: advances in tissue selective estrogen complexes and selective estrogen receptor modulators.
Topics: Adult; Aged; Atrophy; Breast Neoplasms; Estrogens, Conjugated (USP); Female; Female Urogenital Diseases; Hot Flashes; Humans; Indoles; Middle Aged; Osteoporosis, Postmenopausal; Postmenopause; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Tamoxifen; Vagina | 2019 |
Use of SERMs for treatment in postmenopausal women.
Topics: Breast Neoplasms; Clinical Trials as Topic; Dyspareunia; Estrogens, Conjugated (USP); Female; Hot Flashes; Humans; Indoles; Osteoporosis; Osteoporosis, Postmenopausal; Postmenopause; Pyrrolidines; Raloxifene Hydrochloride; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Tamoxifen; Tetrahydronaphthalenes; Toremifene | 2014 |
Effect of selective estrogen receptor modulators on metabolic homeostasis.
Topics: Animals; Breast; Breast Neoplasms; Diabetes Mellitus, Type 2; Disease Models, Animal; Estrogens; Female; Humans; Indoles; Metabolic Syndrome; Osteoporosis, Postmenopausal; Receptors, Estrogen; Uterus | 2016 |
From the Women's Health Initiative to the combination of estrogen and selective estrogen receptor modulators to avoid progestin addition.
Topics: Breast Neoplasms; Coronary Disease; Estrogen Receptor alpha; Estrogen Replacement Therapy; Estrogens; Estrogens, Conjugated (USP); Female; Humans; Indoles; Menopause; Progestins; Selective Estrogen Receptor Modulators; Venous Thromboembolism; Women's Health | 2015 |
Selective estrogen receptor modulators and the combination therapy conjugated estrogens/bazedoxifene: A review of effects on the breast.
Topics: Animals; Breast; Breast Neoplasms; Drug Therapy, Combination; Estradiol; Estrogen Antagonists; Estrogens; Estrogens, Conjugated (USP); Female; Fulvestrant; Humans; Indoles; Osteoporosis; Postmenopause; Protective Factors; Raloxifene Hydrochloride; Risk Assessment; Selective Estrogen Receptor Modulators; Tamoxifen; Toremifene | 2015 |
Preclinical breast effects of a tissue selective estrogen complex (TSEC) including conjugated estrogen with bazedoxifene.
Topics: Animals; Apoptosis; Breast Neoplasms; Cell Proliferation; Estrogens; Estrogens, Conjugated (USP); Female; Humans; Indoles; Selective Estrogen Receptor Modulators | 2017 |
The evolving role of oral hormonal therapies and review of conjugated estrogens/bazedoxifene for the management of menopausal symptoms.
Topics: Age Factors; Bone Remodeling; Breast Neoplasms; Cardiovascular Diseases; Drug Administration Routes; Drug Combinations; Endometrial Hyperplasia; Estrogen Replacement Therapy; Estrogens, Conjugated (USP); Female; Hot Flashes; Humans; Indoles; Menopause; Osteoporosis, Postmenopausal; Quality of Life; Randomized Controlled Trials as Topic; Selective Estrogen Receptor Modulators; Sleep Wake Disorders; Time Factors; Vagina | 2017 |
New selective estrogen receptor modulators (SERMs) in development.
Topics: Bone Density Conservation Agents; Breast Neoplasms; Female; Humans; Indoles; Osteoporosis; Piperidines; Pyrrolidines; Risk Factors; Selective Estrogen Receptor Modulators; Tetrahydronaphthalenes; Thiophenes | 2010 |
The evolution of selective estrogen receptor modulators in osteoporosis therapy.
Topics: Aged; Aged, 80 and over; Bone Density; Bone Density Conservation Agents; Breast Neoplasms; Endometrial Neoplasms; Female; Fractures, Bone; Hot Flashes; Humans; Indoles; Middle Aged; Osteoporosis, Postmenopausal; Pyrrolidines; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Spinal Fractures; Tetrahydronaphthalenes | 2012 |
[Third generation selective estrogen receptor modulators: benefits beyond bone. II, endometrial action].
Topics: Adenocarcinoma; Animals; Breast Neoplasms; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation, Preclinical; Endometrial Neoplasms; Endometrium; Estradiol; Estrogen Replacement Therapy; Estrogens, Conjugated (USP); Female; Hot Flashes; Humans; Indoles; Menopause; Multicenter Studies as Topic; Organ Specificity; Osteoporosis, Postmenopausal; Piperidines; Pyrrolidines; Rats; Selective Estrogen Receptor Modulators; Tamoxifen; Tetrahydronaphthalenes; Thiophenes; Thromboembolism | 2013 |
[Therapeutic agents for disorders of bone and calcium metabolism: Bazedoxifene].
Topics: Animals; Breast Neoplasms; Cholesterol; Female; Fractures, Spontaneous; Hot Flashes; Humans; Indoles; Osteoporosis, Postmenopausal; Rats; Selective Estrogen Receptor Modulators; Uterus | 2007 |
3 trial(s) available for bazedoxifene and Breast Cancer
| Article | Year |
|---|---|
Clinical Efficacy and Whole-Exome Sequencing of Liquid Biopsies in a Phase IB/II Study of Bazedoxifene and Palbociclib in Advanced Hormone Receptor-Positive Breast Cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Exome Sequencing; Female; Humans; Liquid Biopsy; Receptor, ErbB-2; Receptors, Estrogen; Treatment Outcome | 2022 |
Effect of Bazedoxifene and Conjugated Estrogen (Duavee) on Breast Cancer Risk Biomarkers in High-Risk Women: A Pilot Study.
Topics: Aged; Biomarkers, Tumor; Breast; Breast Density; Breast Neoplasms; Estradiol; Estrogen Replacement Therapy; Estrogens, Conjugated (USP); Feasibility Studies; Female; Humans; Indoles; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Ki-67 Antigen; Mammography; Menopause; Middle Aged; Pilot Projects; Postmenopause; Progesterone; Quality of Life; Risk Factors; Testosterone; Vasomotor System | 2019 |
Breast density changes in a randomized controlled trial evaluating bazedoxifene/conjugated estrogens.
Topics: Breast; Breast Density; Breast Neoplasms; Double-Blind Method; Estrogens, Conjugated (USP); Female; Humans; Indoles; Mammary Glands, Human; Mammography; Middle Aged; Placebos; Postmenopause; Selective Estrogen Receptor Modulators | 2013 |
16 other study(ies) available for bazedoxifene and Breast Cancer
| Article | Year |
|---|---|
Design and Synthesis of Basic Selective Estrogen Receptor Degraders for Endocrine Therapy Resistant Breast Cancer.
Topics: Animals; Apoptosis; Aromatase Inhibitors; Breast Neoplasms; Cell Proliferation; Drug Design; Drug Resistance, Neoplasm; Estrogen Receptor alpha; Female; Humans; Mice; Mice, Inbred C57BL; Mice, Nude; Mutation; Proteolysis; Rats; Rats, Sprague-Dawley; Selective Estrogen Receptor Modulators; Thiophenes; Tissue Distribution; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2019 |
Comparative safety of conjugated estrogens/bazedoxifene versus estrogen/progestin combination hormone therapy among women in the United States: a multidatabase cohort study.
Topics: Breast Neoplasms; Endometrial Hyperplasia; Endometrial Neoplasms; Estrogen Replacement Therapy; Estrogens; Female; Humans; Incidence; Selective Estrogen Receptor Modulators; United States | 2023 |
Bispecific Estrogen Receptor α Degraders Incorporating Novel Binders Identified Using DNA-Encoded Chemical Library Screening.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Click Chemistry; DNA; Estrogen Antagonists; Estrogen Receptor alpha; Female; Half-Life; Humans; Indoles; Kinetics; Mice; Small Molecule Libraries; Structure-Activity Relationship; Xenograft Model Antitumor Assays | 2021 |
The evolving use of SERDs in estrogen receptor-positive, HER2-negative metastatic breast cancer.
Topics: Antineoplastic Agents, Hormonal; Breast Neoplasms; Estrogen Receptor Antagonists; Female; Fulvestrant; Humans; Indoles; Neoplasm Metastasis; Receptor, ErbB-2; Receptors, Estrogen; Selective Estrogen Receptor Modulators | 2021 |
The SERM/SERD bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells.
Topics: Breast Neoplasms; Drug Resistance, Neoplasm; Estrogen Receptor alpha; Female; Fulvestrant; Humans; Indoles; Ligands; MCF-7 Cells; Mutant Proteins; Mutation; Piperazines; Protein Binding; Protein Domains; Protein Structure, Secondary; Pyridines; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Structure-Activity Relationship; Tamoxifen | 2018 |
Bazedoxifene exhibits antiestrogenic activity in animal models of tamoxifen-resistant breast cancer: implications for treatment of advanced disease.
Topics: Animals; Antineoplastic Agents, Hormonal; Breast Neoplasms; Drug Resistance, Neoplasm; Estrogen Antagonists; Estrogen Receptor alpha; Female; Humans; Indoles; MCF-7 Cells; Mice; Mice, Nude; Protein Conformation; Protein Stability; Proteolysis; Tamoxifen; Tumor Burden; Xenograft Model Antitumor Assays | 2013 |
A(nother) scientific strategy to prevent breast cancer in postmenopausal women by enhancing estrogen-induced apoptosis?
Topics: Aged; Apoptosis; Breast Neoplasms; Estrogens; Estrogens, Conjugated (USP); Female; Hot Flashes; Humans; Hysterectomy; Indoles; Middle Aged; Postmenopause; Selective Estrogen Receptor Modulators; Women's Health | 2014 |
Gene expression profiling studies of three SERMs and their conjugated estrogen combinations in human breast cancer cells: insights into the unique antagonistic effects of bazedoxifene on conjugated estrogens.
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cluster Analysis; Down-Regulation; Estradiol; Estrogen Antagonists; Estrogens, Conjugated (USP); Female; Gene Expression; Gene Expression Profiling; Humans; Indoles; Oligonucleotide Array Sequence Analysis; Pyrrolidines; Raloxifene Hydrochloride; Reverse Transcriptase Polymerase Chain Reaction; Selective Estrogen Receptor Modulators; Signal Transduction; Tetrahydronaphthalenes; Up-Regulation | 2010 |
Third-generation SERMs may face uphill battle.
Topics: Anticarcinogenic Agents; Bone Density Conservation Agents; Breast Neoplasms; Clinical Trials as Topic; Drug Approval; Drug Industry; Estradiol; Evidence-Based Medicine; Female; Fractures, Bone; Humans; Indoles; Osteoporosis, Postmenopausal; Patents as Topic; Primary Prevention; Pyrrolidines; Raloxifene Hydrochloride; Receptors, Estrogen; Risk; Selective Estrogen Receptor Modulators; Tamoxifen; Tetrahydronaphthalenes; United States; United States Food and Drug Administration | 2010 |
The gynecologic effects of lasofoxifene, an estrogen agonist/antagonist, in postmenopausal women.
Topics: Breast Neoplasms; Estrogen Antagonists; Estrogens; Female; Female Urogenital Diseases; Humans; Indoles; Osteoporosis, Postmenopausal; Postmenopause; Pyrrolidines; Raloxifene Hydrochloride; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Tamoxifen; Tetrahydronaphthalenes | 2011 |
The selective estrogen receptor modulator bazedoxifene inhibits hormone-independent breast cancer cell growth and down-regulates estrogen receptor α and cyclin D1.
Topics: Binding Sites; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Crystallography, X-Ray; Cyclin D1; Down-Regulation; Estrogen Receptor alpha; Female; Gene Knockdown Techniques; Humans; Indoles; Luciferases, Renilla; Selective Estrogen Receptor Modulators | 2011 |
Binding capacity of ER-α ligands and SERMs: comparison of the human, dog and cat.
Topics: Amino Acid Sequence; Animals; Antineoplastic Agents; Breast Neoplasms; Cats; Chalcones; Dogs; Estrogen Receptor alpha; Female; Hesperidin; Humans; Indoles; Ligands; Mammary Glands, Animal; Mammary Glands, Human; Molecular Sequence Data; Protein Structure, Secondary; Selective Estrogen Receptor Modulators; Sequence Alignment; Sequence Analysis, Protein | 2011 |
Effects of bazedoxifene acetate with and without conjugated equine estrogens on the breast of postmenopausal monkeys.
Topics: Animals; Biopsy; Breast Neoplasms; Cell Proliferation; Drug Evaluation, Preclinical; Epithelial Cells; Estrogen Receptor alpha; Estrogen Replacement Therapy; Estrogens, Conjugated (USP); Female; Indoles; Ki-67 Antigen; Macaca fascicularis; Mammary Glands, Animal; Models, Animal; Ovariectomy; Risk Factors; Selective Estrogen Receptor Modulators | 2012 |
Inhibitory effects of a bazedoxifene/conjugated equine estrogen combination on human breast cancer cells in vitro.
Topics: Amphiregulin; Breast Neoplasms; EGF Family of Proteins; Estradiol; Estrogens, Conjugated (USP); Female; Glycoproteins; Humans; Indoles; Intercellular Signaling Peptides and Proteins; MCF-7 Cells; Proto-Oncogene Proteins c-myc; Trefoil Factor-1; Tumor Suppressor Proteins | 2013 |
A rose without thorns? Neutralizing the vice and magnifying the virtue of conjugated equine estrogens.
Topics: Breast; Breast Density; Breast Neoplasms; Estrogens, Conjugated (USP); Female; Humans; Indoles; Mammary Glands, Human; Postmenopause; Radiography | 2013 |
Bazedoxifene acetate: a selective estrogen receptor modulator with improved selectivity.
Topics: Animals; Body Temperature Regulation; Bone and Bones; Bone Density; Breast Neoplasms; Carcinoma, Hepatocellular; Cell Division; Cell Line, Tumor; CHO Cells; Compressive Strength; Cricetinae; Endometrium; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Female; Humans; Indoles; Ligands; Lipids; Liver Neoplasms; Neurons; Osteoblasts; Rats; Rats, Sprague-Dawley | 2005 |