bay-k-8644 has been researched along with Reperfusion Injury in 4 studies
3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester: A dihydropyridine derivative, which, in contrast to NIFEDIPINE, functions as a calcium channel agonist. The compound facilitates Ca2+ influx through partially activated voltage-dependent Ca2+ channels, thereby causing vasoconstrictor and positive inotropic effects. It is used primarily as a research tool.
Bay-K-8644 : A racemate comprising equimolar amounts of (R)- and (S)-Bay-K-8644
methyl 2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3-carboxylate : A pentasubstituted dihydropyridine carrying methoxycarbonyl, 2-(trifluoromethyl)phenyl and nitro substituents at positions 3, 4 and 5 respectively as well as two methyl substituents at positions 2 and 6.
Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Grześk, E | 1 |
| Darwish, N | 1 |
| Stolarek, W | 1 |
| Wiciński, M | 1 |
| Malinowski, B | 1 |
| Burdziński, I | 1 |
| Grześk, G | 2 |
| Szadujkis-Szadurska, K | 1 |
| Szadujkis-Szadurski, R | 1 |
| Szadujkis-Szadurski, L | 1 |
| Słupski, M | 1 |
| Matusiak, G | 1 |
| Gajdus, M | 1 |
| Glaza, I | 1 |
| Zhang, H | 1 |
| Liu, S | 1 |
| Wang, X | 1 |
| Zhang, C | 1 |
| Thompson, M | 1 |
| Westwick, J | 1 |
| Woodward, B | 1 |
4 other studies available for bay-k-8644 and Reperfusion Injury
| Article | Year |
|---|---|
Effect of reperfusion on vascular smooth muscle reactivity in three contraction models.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2019 |
The role of calcium in modulating the reactivity of the smooth muscle cells during ischemia/reperfusion. Part 1.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2010 |
[Protective effect of calcium channel agonist BayK8644 on lungs against ischemia-reperfusion injury in rabbits].
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2010 |
Responses to endothelins-1, -2, and -3 and sarafotoxin 6c after ischemia/reperfusion in isolated perfused rat heart: role of vasodilator loss.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1995 |