Page last updated: 2024-10-23

bay-k-8644 and Muscle Contraction

bay-k-8644 has been researched along with Muscle Contraction in 316 studies

3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester: A dihydropyridine derivative, which, in contrast to NIFEDIPINE, functions as a calcium channel agonist. The compound facilitates Ca2+ influx through partially activated voltage-dependent Ca2+ channels, thereby causing vasoconstrictor and positive inotropic effects. It is used primarily as a research tool.
Bay-K-8644 : A racemate comprising equimolar amounts of (R)- and (S)-Bay-K-8644
methyl 2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3-carboxylate : A pentasubstituted dihydropyridine carrying methoxycarbonyl, 2-(trifluoromethyl)phenyl and nitro substituents at positions 3, 4 and 5 respectively as well as two methyl substituents at positions 2 and 6.

Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Research Excerpts

ExcerptRelevanceReference
"In attempt to characterize tetrandrine on pulmonary hypertension, biological activities induced by a range of mediators implicated in the pathogenesis of pulmonary hypertension were investigated."7.71Effects of tetrandrine on smooth muscle contraction induced by mediators in pulmonary hypertension. ( Chang, TH; Wang, HL; Zhang, XH, 2002)
"In attempt to characterize tetrandrine on pulmonary hypertension, biological activities induced by a range of mediators implicated in the pathogenesis of pulmonary hypertension were investigated."3.71Effects of tetrandrine on smooth muscle contraction induced by mediators in pulmonary hypertension. ( Chang, TH; Wang, HL; Zhang, XH, 2002)
"The hypothesis that Ca2+ channel function is altered during pregnancy was tested by comparing responses to potassium chloride (KCl) and phenylephrine in aortic rings of virgin and term-pregnant rats under the influence of nifedipine and Bay K 8644."3.69Effects of nifedipine and Bay K 8644 on myotropic responses in aortic rings of pregnant rats. ( Brochu, M; Roy, B; Sicotte, B; St-Louis, J, 1995)
"The influence of deuterium oxide (D2O) on calcium-dependent vascular smooth muscle contraction was investigated."3.68Deuterium oxide reduces agonist and depolarization-induced contraction of rat aortic rings. ( Liepins, A; McWilliam, TM; Rankin, AJ, 1990)
"The effects of divalent ionophores (A23187 and ionomycin), Ca2+ channel agonist (BAY K 8644), and protein kinase C (C-kinase) activators [phorbol 12-myristate 13-acetate (PMA), mezerein] on bovine tracheal smooth muscle contraction were investigated."3.67Activation of tracheal smooth muscle contraction: synergism between Ca2+ and activators of protein kinase C. ( Park, S; Rasmussen, H, 1985)
"Cardiac arrhythmias associated with intracellular calcium inhomeostasis are refractory to antiarrhythmic therapy."1.46Inhibition of late sodium current suppresses calcium-related ventricular arrhythmias by reducing the phosphorylation of CaMK-II and sodium channel expressions. ( Chu, YP; Ding, YS; Huang, SH; Huo, Y; Ren, L; Wang, P; Wei, XH; Wu, L; Yang, QM; Yang, W; Yu, SD, 2017)
"Dehydroeffusol is a naturally occurring phenanthrene isolated from Juncus effusus."1.40Effects of dehydroeffusol on spasmogen-induced contractile responses of rat intestinal smooth muscles. ( Di, F; Huang, J; Li, P; Zhai, H, 2014)
" Dose-response analyses revealed a structure-activity relationship where the larger the side-chain the higher the inhibitory potency."1.33Functional inhibition of intestinal and uterine muscles by non-permeant triphenylethylene derivatives. ( Díaz, M; García Marrero, B; Gómez, T; Marrero-Alonso, J, 2006)
"Pretreatment with wortmannin (300 nmol/l), an inhibitor of myosin light chain kinase, decreased both contractility and phosphorylation of myosin light chains in parallel."1.32Heat-shock response is associated with enhanced contractility of vascular smooth muscle in isolated rat aorta. ( Cho, JW; Kang, BS; Kim, CY; Kim, IK; Kim, YH; Park, TG, 2004)
"Ramipril treatment decreased systolic pressure in WKY and SHR, decreased heart weight and heart weight-to-body weight ratio in SHR, and decreased body weight in WKY."1.31Ramipril treatment alters Ca(2+) and K(+) channels in small mesenteric arteries from Wistar-Kyoto and spontaneously hypertensive rats. ( Cox, RH; Dietz, NJ; Lozinskaya, I; Matsuda, K, 2002)
" However, the inhibition of the combined CPA and CCh response was reduced and the dose-response curve of SIN-1 shifted to the right."1.30Involvement of intracellular Ca2+ stores in inhibitory effects of NO donor SIN-1 and cGMP. ( Allescher, HD; Franck, H; Puschmann, A; Schusdziarra, V; Storr, M, 1998)
"Ryanodine inhibited the increase in the maximal rate of rise of [Ca2+]i resulting in abolishment of the correlation between force and the maximal rate of rise of [Ca2+]i."1.30Tight coupling between the rate of rise of Ca2+ transient and peak twitch contraction in guinea-pig papillary muscle. ( Endoh, M; Hori, M; Karaki, H; Miyamoto, S; Ozaki, H, 1999)
"Treatment with ramipril reduced blood pressure and force development in response to Bay K8644 in adult SHRSP, although not to levels of WKY rats, whereas WKY rats were unaffected by treatment."1.29Angiotensin-converting enzyme inhibition during development alters calcium regulation in adult hypertensive rats. ( Traub, O; Webb, RC, 1993)
"Nifedipine was equipotent in inhibiting the tonic response at all times tested, while a marked time-dependency of inhibition toward phasic responses was observed."1.29A pharmacological analysis of calcium channels involved in phasic and tonic responses of the guinea-pig ureter to high potassium. ( Giuliani, S; Maggi, CA, 1995)
"A 3% halothane-induced increase in [Ca2+]cyt was observed in the Ca(2+)-free solution even when the muscle strip was pretreated with a 10(-6)-M dose of ryanodine and a 20-mM dose of caffeine, whereas it was abolished completely after the muscle strip was pretreated with ryanodine, caffeine, and 100 nM norepinephrine."1.29Effects of halothane and isoflurane on cytosolic calcium ion concentrations and contraction in the vascular smooth muscle of the rat aorta. ( Fujita, S; Namba, H; Namiki, A; Notsuki, E; Tsuchida, H; Yamakage, M, 1993)
"To investigate the role of hyperinsulinemia/insulin resistance in vasomotor tone regulation, we studied the effects of vasoactive substances on tension and intracellular free calcium concentration ([Ca2+]i) of aortic smooth muscle derived from rats that were made hyperinsulinemic by insulin infusion and from Zucker obese rats with insulin resistance."1.29Augmented contractile function and abnormal Ca2+ handling in the aorta of Zucker obese rats with insulin resistance. ( Akishita, M; Han, SZ; Kim, S; Kozaki, K; Orimo, H; Ouchi, Y; Toba, K, 1996)
"Isoflurane has a lesser ability than halothane to induce contracture in malignant hyperthermia (MH) muscle in vitro."1.28Effect of Bay K 8644 on the magnitude of isoflurane and halothane contracture of skeletal muscle from patients susceptible to malignant hyperthermia. ( Adamantidis, MM; Adnet, PJ; Haudecoeur, G; Imbenotte, M; Krivosic-Horber, RM; Reyford, H, 1992)
"Fraxinellone and verapamil were more potent and effective in producing relaxation in 60 mmol/l than in 15 mmol/l K(+)-induced contraction."1.28Vasorelaxing effect in rat thoracic aorta caused by fraxinellone and dictamine isolated from the Chinese herb Dictamnus dasycarpus Turcz: comparison with cromakalim and Ca2+ channel blockers. ( Huang, TF; Ko, FN; Su, MJ; Teng, CM; Wang, ML; Wu, TS; Yu, SM, 1992)
"Effects of Bay K 8644, partial depolarization with high potassium, and nifedipine on the dose-response curves of the rat vas deferens to norepinephrine, methacholine and KCI were investigated in HEPES-buffered physiological salt solution (PSS) with or without 20 mM sodium bicarbonate."1.28Bicarbonate-dependent action of Bay K 8644 in the smooth muscle of the rat vas deferens. ( Gomi, Y; Suzuki, N, 1990)
"Nifedipine blocked this increase as well as 45Ca2+ uptake elicited by NA and K+."1.28Pharmacological dissection of Ca2+ channels in the rat aorta by Ca2+ entry modulators. ( Alonso, MJ; Marín, J; Rico, I; Salaices, M, 1990)
"1."1.28Pharmacological studies of human erectile tissue: characteristics of spontaneous contractions and alterations in alpha-adrenoceptor responsiveness with age and disease in isolated tissues. ( Christ, GJ; Maayani, S; Melman, A; Valcic, M, 1990)
"Carbachol was applied at 20 degrees C for 5 min."1.28Carbachol-induced nonspecific desensitization in guinea-pig ileum. ( Casteels, R; Droogmans, G; Himpens, B, 1991)
"The dose-response effects of BAY K 8644 and nifedipine on diaphragmatic contractility were assessed in vitro."1.28Multiple effects of BAY K 8644 and nifedipine on isolated diaphragmatic fibers in vitro. ( Aubier, M; Pavlovic, D; Viires, N, 1991)
"0 nM) on dose-response curves to noradrenaline, histamine, calcium (Ca2+) and potassium (K+) in ring preparations of rabbit basilar artery and central ear artery."1.28The selective potentiation of noradrenaline-induced tone by Bay K 8644 in the rabbit basilar artery. ( Bevan, JA; Dowd, AL; Germann, P; Laher, I, 1989)
" Nifedipine (3 X 10(-7) M) produced a parallel shift to the right of the dose-response curve to BAY-K-8644, whereas 5 X 10(-6)M verapamil markedly reduced the responses evoked by all concentrations of this drug."1.27The effects of BAY-K-8644 on the contraction of cat middle cerebral and femoral arteries. ( Marin, J; Reviriego, J; Salaices, M; Sanchez-Ferrer, CF, 1985)
" BAY K 8644, in either potassium buffer, induced a statistically significant shift to the left in the norepinephrine dose-response curve."1.27The facilitative actions of Bay K 8644 on norepinephrine and KCl-induced contractures of rabbit aortic rings. ( Babich, M; Piascik, MT, 1986)
"Nifedipine was less efficacious in relaxing the contractile response to Bay k 8644 compared to the contractile response to K+ in SHRs femoral arteries."1.27Contractile effects of Bay k 8644, a dihydropyridine calcium agonist, on isolated femoral arteries from spontaneously hypertensive rats. ( Aoki, K; Asano, M; Matsuda, T, 1986)
"Caffeine may inhibit noradrenalineinduced Ca2' release."1.27Inhibitory effects of caffeine on contractions and calcium movement in vascular and intestinal smooth muscle. ( Ahn, HY; Karaki, H; Urakawa, N, 1988)

Research

Studies (316)

TimeframeStudies, this research(%)All Research%
pre-1990107 (33.86)18.7374
1990's162 (51.27)18.2507
2000's29 (9.18)29.6817
2010's16 (5.06)24.3611
2020's2 (0.63)2.80

Authors

AuthorsStudies
Sunkel, CE1
Fau de Casa-Juana, M1
Santos, L1
García, AG1
Artalejo, CR1
Villarroya, M1
González-Morales, MA1
López, MG1
Cillero, J1
Alonso, S1
Glossmann, H1
Striessnig, J1
Vo, D2
Matowe, WC2
Ramesh, M2
Iqbal, N1
Wolowyk, MW2
Howlett, SE1
Knaus, EE2
Akula, MR1
Dagnino, L1
Li-Kwong-Ken, MC1
Trezza, A1
Spiga, O1
Mugnai, P1
Saponara, S2
Sgaragli, G2
Fusi, F3
Wiciński, M2
Malinowski, B2
Rajewski, P1
Szychta, P1
Wódkiewicz, E1
Walczak, M1
Górski, K1
Pawlak-Osińska, K1
Słupski, M2
Wei, XH1
Yu, SD1
Ren, L1
Huang, SH1
Yang, QM1
Wang, P1
Chu, YP1
Yang, W1
Ding, YS1
Huo, Y1
Wu, L1
Zawieja, SD1
Castorena-Gonzalez, JA1
Scallan, JP1
Davis, MJ1
Szadujkis-Szadurska, K2
Grzesk, G2
Szadujkis-Szadurski, L2
Gajdus, M2
Di, F1
Zhai, H1
Li, P1
Huang, J1
Al Dera, H1
Callaghan, BP1
Brock, JA1
Patejdl, R1
Leroux, AC1
Noack, T3
Vasconcelos, LH1
Correia, AC1
de Souza, IL1
Silva, Mda C1
Paredes-Gamero, EJ2
Santos, BV1
Cavalcante, Fde A1
da Silva, BA2
Pitake, S1
Ochs, RS1
Muneer, A1
Cellek, S1
Ralph, DJ1
Minhas, S1
Lai, HH1
Smith, CP1
Munoz, A1
Boone, TB1
Szigeti, GP1
Somogyi, GT1
Daniel, EE7
Eteraf, T1
Sommer, B1
Cho, WJ1
Elyazbi, A1
Han, JH2
Lee, MY3
Lee, SY2
Chang, IH1
Kim, HJ1
Kim, W1
Myung, SC3
Chang, GJ1
Lin, TP1
Ko, YS1
Lin, MS1
Szadujkis-Szadurski, R1
Matusiak, G1
Glaza, I1
Alvarez, SM1
Miner, AS1
Browne, BM1
Ratz, PH5
Park, SH1
Kim, TH1
Moon, YT1
Santos, RF1
Martins, IR1
Travassos, RA1
Tavares, JF1
Silva, MS1
Ferreira, AT1
Nouailhetas, VL1
Aboulafia, J1
Rigoni, VL1
Hibberd, TJ1
Zagorodnyuk, VP1
Spencer, NJ1
Brookes, SJ1
Hernandez, JM1
Janssen, LJ1
Cox, RH1
Lozinskaya, I1
Matsuda, K1
Dietz, NJ1
Wang, HL1
Zhang, XH1
Chang, TH1
Yaris, E1
Kesim, M1
Kadioglu, M1
Kalyoncu, NI1
Ulku, C1
Ozyavuz, R1
Frosini, M1
Gorelli, B1
Kim, IK1
Park, TG1
Kim, YH1
Cho, JW1
Kang, BS1
Kim, CY1
Teixeira, CE1
Corrado, AP1
De Nucci, G3
Antunes, E1
Muinuddin, A2
Kang, Y2
Gaisano, HY2
Diamant, NE2
Ji, J1
Sheu, L1
Nakahara, T1
Mitani, A1
Kubota, Y1
Maruko, T1
Sakamoto, K2
Tanaka, Y3
Koike, K1
Shigenobu, K1
Ishii, K1
Boddy, G1
Forrest, A1
Molleman, A1
Parsons, M1
Marrero-Alonso, J1
García Marrero, B1
Gómez, T1
Díaz, M2
Keum, EM1
Park, SY1
Kim, SC1
Ng, YK1
de Groat, WC1
Wu, HY1
Shen, J1
Yip, S1
Wang, Z1
Wang, W1
Xing, D1
Du, L1
Morelli, A1
Squecco, R1
Failli, P1
Filippi, S1
Vignozzi, L1
Chavalmane, AK1
Fibbi, B1
Mancina, R1
Luciani, G1
Gacci, M1
Colli, E1
Francini, F1
Adorini, L1
Maggi, M1
Hyland, L2
Warnock, P2
Docherty, JR2
Kanmura, Y1
Itoh, T1
Kuriyama, H1
Su, CM2
Swamy, VC1
Triggle, DJ5
Usowicz, MM1
Gigg, M1
Jones, LM1
Cheung, CW1
Hartley, SA1
Hirota, K2
Zsigmond, EK2
Matsuki, A2
Rabito, SF2
Roy, B1
Sicotte, B1
Brochu, M1
St-Louis, J1
Asano, M6
Masuzawa-Ito, K1
Matsuda, T3
Suzuki, Y1
Oyama, H1
Shibuya, M1
Sugita, K1
Traub, O2
Webb, RC4
Hayakawa, M1
Ito, KM1
Ito, K1
Gustafsson, H1
Nilsson, H1
Okamura, H1
Fujitani, B1
Furukawa, K1
Une, T1
Nukuda, T1
Komiya, M1
Kurokawa, M1
Barrios, M2
Robles, I1
Baeyens, JM3
Liu, J1
Hill, MA1
Meininger, GA1
Antonaccio, MJ1
Normandin, D1
Dehpour, AR1
Tajkhorshid, E1
Behbahani, NR1
Kitamura, N1
Ohta, T1
Ito, S1
Nakazato, Y1
Maggi, CA8
Giuliani, S4
Santicioli, P4
Poli, E2
Pozzoli, C1
Coruzzi, G2
Bertaccini, G2
Masters, AK1
Huddart, H2
Hetherington, AM1
Watts, SW1
Sakai, Y1
Inazu, M1
Shamoto, A1
Zhu, B1
Homma, I1
Oz, M3
Frank, GB3
Franck, H2
Puschmann, A2
Schusdziarra, V3
Allescher, HD3
Lau, WA1
Ventura, S1
Jiang, Q1
Pennefather, JN1
Meini, S1
Höppner, CK1
Stief, CG1
Jonas, U1
Mandrek, K2
Golenhofen, K2
Kato, T1
Saito, M1
Kondo, A1
Pérez Vallina, JR1
Cantabrana, B2
Hidalgo, A3
Barrús, MT2
Reviriego, J3
Marín, J9
Nelson, MT3
Cheng, H1
Rubart, M1
Santana, LF1
Bonev, AD1
Knot, HJ1
Lederer, WJ1
Morales, MA1
Silva, A1
Brito, G1
Bustamante, S1
Ponce, H1
Paeile, C1
Fernández, AI1
García de Boto, MJ2
Gutiérrez, M1
Kenny, BA1
Fraser, S1
Spedding, M3
Tsuchida, H1
Namba, H1
Yamakage, M1
Fujita, S1
Notsuki, E1
Namiki, A1
Foster, PS1
Denborough, MA1
Hagiwara, S1
Mitsui, M2
Karaki, H10
Storm, DS1
Ozaki, H4
Gerthoffer, WT1
Hori, M2
Sanders, KM3
Publicover, NG2
Pichoff, BE1
Uyehara, CF1
Nakamura, KT1
Bourreau, JP3
Kwan, CY3
Van Overloop, B1
Stoclet, JC3
Gairard, A1
Callahan, PE1
Lattanzio, FA2
Kadlec, O1
Schuurkes, J1
Seferna, I1
Aleixandre, MA1
King, AP1
Puerro, M1
Ko, FN2
Wu, YC1
Lu, ST1
Teng, CM2
Kishi, Y1
Watanabe, T1
Makita, T1
Sakita, S1
Watanabe, R1
Ashikaga, T1
Numano, F1
Hernández, MC2
Salaices, M4
Ponte, A1
Alonso, MJ3
Sánchez-Ferrer, CF4
Rodriguez, J1
Ouchi, Y1
Han, SZ1
Kim, S1
Akishita, M1
Kozaki, K1
Toba, K1
Orimo, H1
Liu, YA1
Ostlund, E1
Fried, G1
Sato, T1
Jinsi, A1
Paradise, J1
Deth, RC1
Shuttleworth, CW1
Koh, SD1
Bayginov, O1
Salomone, S1
Dessy, C1
Morel, N2
Godfraind, T3
Petkov, GV2
Boev, KK2
Yamazawa, T1
Takeshima, H1
Sakurai, T1
Endo, M1
Iino, M1
Montaño, LM1
Barajas-Lopez, C1
Oba, T3
Koshita, M1
Aoki, T2
Yamaguchi, M3
Mulè, F1
Serio, R1
Erxleben, C1
Rathmayer, W1
Miwa, T1
Endou, M1
Okumura, F1
Kageyama, M1
Fujita, H1
Nakata, K1
Shirasawa, E1
Ma, L1
Robinson, CP1
Thadani, U1
Patterson, E1
Sims, SM1
Jiao, Y1
Preiksaitis, HG1
Shenfeld, OZ1
Morgan, CW1
Nasu, T2
Sasaki, M2
Shibata, H1
Storr, M1
Salapatek, AM1
Lam, A1
Tiritilli, A1
Yan, L1
Gong, GX1
Tse, J1
Scholz, PM1
Weiss, HR1
Valoti, M1
Sgaragli, GP1
Hukovic, N1
Hadziselimovic, R1
Moreau, R1
Oberti, F1
Lahaye, P1
Gadano, A1
Cailmail, S1
Sogni, P1
Cales, P1
Lebrec, D1
Bell, KL1
Kemp, BK1
McPherson, GA1
Hodgson, WC1
Nomura, Y2
Taylor, MS1
Gao, H1
Gardner, JD1
Benoit, JN1
Rácz, D1
Zillikens, S1
Forstreuter, P1
Nagykáldi, Z1
Magyar, K1
Török, T1
Miyamoto, S1
Endoh, M1
Ren, J1
Jefferson, L1
Sowers, JR1
Brown, RA1
Monterrubio, J1
Lizardi, L1
Zuazaga, C1
Shi, XZ1
Sarna, SK2
Zavecz, JH1
Bueno, O1
Maloney, RE1
O'Donnell, JM1
Roerig, SC1
Battarbee, HD1
Tchugunova, Y1
Dinç, M1
Gomez, JP1
Ghisdal, P1
Gonzalez, A1
Masui, H1
Wakabayashi, I2
Siogawa, K1
Koizumi, N1
Yang, X1
Henson, OW1
Qian, YM1
Huang, YH1
Fick, H1
Classen, M1
Ben-Harari, RR1
Stenner, M1
Sutin, KM1
Kim, BK1
Satoh, T1
Moriyama, T1
Kuriki, H1
Lecchini, S1
Marcoli, M1
De Ponti, F1
Castelletti, CA1
Frigo, GM1
Diederichs, W1
Sroka, J1
Graff, J1
Zheng, W1
Stoltefuss, J1
Goldmann, S1
Adnet, PJ3
Krivosic-Horber, RM3
Adamantidis, MM3
Haudecoeur, G4
Reyford, H2
Imbenotte, M2
Belis, JA2
Curley, RM2
Murty, VN2
Wagner, CH2
Winter, SJ2
Rohner, TJ2
Guimarães, CL1
Rae, GA3
Candenas, ML1
Naline, E4
Sarria, B3
Advenier, C4
Lydrup, ML1
Himpens, B2
Droogmans, G2
Hellstrand, P1
Somlyo, AP1
Bollen, BA1
McKlveen, RE1
Stevenson, JA1
Yu, SM1
Su, MJ1
Wu, TS1
Wang, ML1
Huang, TF1
Nasa, Y1
Ichihara, K1
Yoshida, R1
Abiko, Y1
Kamishima, T1
Patlak, JB1
Encabo, A1
Ferrer, M1
Villamor, J1
Balfagón, G1
Fernández-Alfonso, MS2
Lu, A2
Sargent, CA1
Vesterqvist, O1
McCullough, JR1
Ogletree, ML1
Grover, GJ1
Yamano, S1
Sako, T1
Kamata, K3
Miyata, N3
Kasuya, Y3
Moreland, S3
Moreland, RS3
Finger, K1
Förster, B1
Valeri, P2
Morrone, LA2
Pimpinella, G1
Romanelli, L1
Suzuki, N2
Gomi, Y2
Martinelli, B1
Severini, C1
White, RE1
Carrier, GO1
O'Neill, SK1
McKay, DW1
Campbell, N1
Triggle, CR2
Crowley, M1
Bolger, GT3
Boonen, HC1
De Mey, JG1
Liard, F1
Jaramillo, J1
Puybasset, L1
Lagente, V1
Dainty, IA1
Bigaud, M1
McGrath, JC2
Katsuragi, T2
Usune, S2
Furukawa, T2
Abiru, T1
Morita, K1
Barrett, EF1
Bruner, CA1
Rico, I2
Abe, M1
Morikawa, M3
Inoue, M1
Tsuboi, M1
Calixto, JB2
Christ, GJ1
Maayani, S1
Valcic, M1
Melman, A1
Worley, JF2
Kotlikoff, MI1
Reyford, GH1
Cordonnier, C2
Morcillo, E1
Cortijo, J1
Esplugues, J1
Biguad, M1
Julou-Schaeffer, G1
Parratt, JR1
Kakishita, E1
Skärby, TV1
Högestätt, ED2
McWilliam, TM1
Liepins, A1
Rankin, AJ1
Stevens, RJ1
Blondfield, DP1
Sakata, K1
Shibata, S4
Satake, N4
Kown, SC1
Kurahashi, K1
Sawada, T1
Kodama, I1
Shoji, T1
Goto, K1
Adams, BA1
Beam, KG1
Geppetti, P1
Del Bianco, E1
Patacchini, R2
Tramontana, M1
Abela, AP1
Williams, JH3
Holland, M2
Lee, JC2
Ward, CW3
McGrath, CJ1
Davy, KP1
Casteels, R1
Wright, G1
Viires, N1
Pavlovic, D1
Aubier, M1
Milusheva, E1
Boev, K1
Papasova, M1
Werner, G1
Addicks, K1
Fricke, U1
Klaus, W1
Sarram, M1
Gielen, W1
Bois, P1
Romey, G1
Lazdunski, M2
Claeson, P1
Zygmunt, P1
Savineau, JP1
Marthan, R4
Crevel, H1
Xu, SF1
Collins, MA1
Chang, KJ1
Nakayama, K2
Ishigai, Y1
Uchida, H1
Dube, GP1
Baik, YH1
Vaghy, PL1
Schwartz, A1
Ildefonse, M1
Jacquemond, V2
Rougier, O2
Renaud, JF1
Fosset, M1
Cheung, DW2
Mikkelsen, E2
Böhm, M1
Burmann, H1
Meyer, W1
Nose, M1
Schmitz, W1
Scholz, H1
Gopalakrishnan, V1
Park, LE1
Preuss, KC1
Gross, GJ1
Brooks, HL1
Warltier, DC1
Lee, CM1
Allen, SL1
Foster, RW1
Small, RC1
Towart, R1
Forder, J1
Scriabine, A1
Rasmussen, H3
Park, S1
Mikkelsen, EO2
Nyborg, NC3
Jakobsen, P1
Matsuo, K2
Uchida, S1
Piascik, MT1
Babich, M1
Aoki, K2
Renier, A1
MacKay, MJ1
Lograno, M1
De Luca, A1
Persichella, M1
Conte-Camerino, D1
Donoso, MV1
Huidobro-Toro, JP1
Kullak, A1
Kozlowski, R1
Ehrhard, P1
Fischli, W1
Osterrieder, W1
Holck, M1
Roy, F1
Pruneau, D1
Wei, XY2
Luchowski, EM1
Rutledge, A1
Armour, CL3
Johnson, PR3
Black, JL3
Tung, LH1
Rand, MJ1
Louis, WJ1
Fovaeus, M2
Andersson, KE2
Batra, S1
Morgan, E1
Sjögren, C2
Rampe, D1
Sulpizio, A1
Hieble, JP1
Ebeigbe, AB1
Aloamaka, CP1
Perlmutter, B1
Kennedy, RH1
Seifen, E1
Soulsby, M1
Takuwa, Y1
Hudspith, MJ1
Brennan, CH1
Charles, S1
Littleton, JM1
Takata, Y1
Kato, H1
Traoré, F1
Cognard, C1
Potreau, D1
Raymond, G1
Uchida, MK1
Agrawal, DK1
McNeill, JH1
Warbanow, W2
Will-Shahab, L2
Litten, RZ1
Suba, EA1
Roth, BL1
Costa, G1
Ahn, HY1
Urakawa, N1
Singh, YN1
Dryden, WF1
Black, J1
Armour, C1
Johnson, P1
Sato, K1
Dulhunty, AF1
Gage, PW1
Huang, BS2
McCumbee, WD2
Wright, GL2
Obianime, AW1
Hirst, SJ1
Dale, MM1
Auguet, M2
Delaflotte, S2
Chabrier, PE1
Pirotzky, E2
Clostre, F2
Braquet, P2
Hai, CM1
Murphy, RA1
Andersson, PO1
Malmgren, A1
Andriantsitohaina, R1
Langton, PD1
Hertle, L1
Nawrath, H1
MacLennan, SJ1
Whittle, MJ1
Silberberg, SD1
Poder, TC1
Lacerda, AE1
Ito, M2
Ohe, M1
Ogata, M1
Shirato, K1
Takishima, T1
Newman, AH1
Rice, KC1
Lueddens, HW1
Basile, AS1
Skolnick, P1
Kashiwabara, T1
Yamada, S1
Hashimoto, H1
Yanagisawa, T1
Taira, N1
D'Orleans-Juste, P2
Finet, M1
Vane, JR2
Stasch, JP1
Kazda, S2
Alfredson, M1
Howl, JD1
Publicover, SJ1
Douglas, SA1
Bowmer, CJ1
Yates, MS1
Bournaud, R1
Shimahara, T1
Garcia, L1
Rieger, F1
Gotoh, Y1
Kumadani, S1
Kawai, T1
Imaizumi, Y1
Watanabe, M1
Turner, NC1
Power, RF1
Polak, JM1
Bloom, SR1
Dollery, CT1
Wilde, DW1
Lee, KS1
Laher, I2
Germann, P1
Dowd, AL2
Bevan, JA2
Vorkapic, P1
Turini, D1
Barbanti, G1
Giachetti, A1
Meli, A1
Adnet, P1
Adamantidis, M1
Krivosic-Horber, R1
Hashimoto, M1
Masumura, S1
Abe, K1
Saito, H1
Matsuki, N1
Lawson, K2
Cavero, I2
García, J1
Amador, M1
Stefani, E1
Del Pozo, E1
Chang, CC1
Chiou, LC1
Hwang, LL1
Hong, SJ1
Huang, CY1
Molderings, GJ1
Schümann, HJ1
Egleme, C1
Al Osachie, I1

Reviews

3 reviews available for bay-k-8644 and Muscle Contraction

ArticleYear
Molecular properties of calcium channels.
    Reviews of physiology, biochemistry and pharmacology, 1990, Volume: 114

    Topics: Amino Acid Sequence; Animals; Base Sequence; Calcium Channels; Cloning, Molecular; DNA; Humans; Mode

1990
Slow channel calcium activators, a new group of pharmacological agents.
    Life sciences, 1985, Oct-07, Volume: 37, Issue:14

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1985
Calcium channels in smooth muscle.
    Annals of the New York Academy of Sciences, 1988, Volume: 522

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1988

Other Studies

313 other studies available for bay-k-8644 and Muscle Contraction

ArticleYear
Synthesis of 3-[(2,3-dihydro-1,1,3-trioxo-1,2-benzisothiazol-2-yl)alkyl] 1,4-dihydropyridine-3,5-dicarboxylate derivatives as calcium channel modulators.
    Journal of medicinal chemistry, 1992, Jun-26, Volume: 35, Issue:13

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1992
Syntheses, calcium channel agonist-antagonist modulation activities, and voltage-clamp studies of isopropyl 1,4-dihydro-2,6-dimethyl-3-nitro-4-pyridinylpyridine-5-carboxylate racemates and enantiomers.
    Journal of medicinal chemistry, 1995, Jul-21, Volume: 38, Issue:15

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1995
Synthesis and calcium channel-modulating effects of alkyl (or cycloalkyl) 1,4-dihydro-2,6-dimethyl-3-nitro-4-pyridyl-5-pyridinecarboxylate racemates and enantiomers.
    Journal of medicinal chemistry, 1998, Feb-12, Volume: 41, Issue:4

    Topics: Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Gui

1998
Functional, electrophysiology, and molecular dynamics analysis of quercetin-induced contraction of rat vascular musculature.
    European journal of pharmacology, 2022, Mar-05, Volume: 918

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2022
Resveratrol's Impact on Vascular Smooth Muscle Cells Hyporeactivity: The Role of Rho-Kinase Inhibition.
    BioMed research international, 2020, Volume: 2020

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2020
Inhibition of late sodium current suppresses calcium-related ventricular arrhythmias by reducing the phosphorylation of CaMK-II and sodium channel expressions.
    Scientific reports, 2017, 04-20, Volume: 7, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2017
Differences in L-type Ca
    American journal of physiology. Heart and circulatory physiology, 2018, 05-01, Volume: 314, Issue:5

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2018
Role of endothelium, acetylocholine and calcium ions in Bay K8644- and KCl-induced contraction.
    Molecular medicine reports, 2013, Volume: 8, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2013
Effects of dehydroeffusol on spasmogen-induced contractile responses of rat intestinal smooth muscles.
    Planta medica, 2014, Volume: 80, Issue:12

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2014
Modified cytoplasmic Ca2+ sequestration contributes to spinal cord injury-induced augmentation of nerve-evoked contractions in the rat tail artery.
    PloS one, 2014, Volume: 9, Issue:10

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2014
Phenytoin inhibits contractions of rat gastrointestinal and portal vein smooth muscle by inhibiting calcium entry.
    Neurogastroenterology and motility, 2015, Volume: 27, Issue:10

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2015
Flavonoid galetin 3,6-dimethyl ether attenuates guinea pig ileum contraction through K(+) channel activation and decrease in cytosolic calcium concentration.
    European journal of pharmacology, 2015, Nov-15, Volume: 767

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2015
Membrane depolarization increases ryanodine sensitivity to Ca2+ release to the cytosol in L6 skeletal muscle cells: Implications for excitation-contraction coupling.
    Experimental biology and medicine (Maywood, N.J.), 2016, Volume: 241, Issue:8

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2016
The investigation of putative agents, using an in vitro model, to prevent cavernosal smooth muscle dysfunction during low-flow priapism.
    BJU international, 2008, Volume: 102, Issue:8

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2008
Activation of cholinergic receptors blocks non-adrenergic non-cholinergic contractions in the rat urinary bladder.
    Brain research bulletin, 2008, Dec-16, Volume: 77, Issue:6

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2008
The role of caveolae and caveolin 1 in calcium handling in pacing and contraction of mouse intestine.
    Journal of cellular and molecular medicine, 2009, Volume: 13, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2009
Effect of low concentrations of hydrogen peroxide on the contractile responses of rat detrusor smooth muscle strips.
    European journal of pharmacology, 2010, Jul-25, Volume: 638, Issue:1-3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2010
Endothelium-dependent and -independent vasorelaxation induced by CIJ-3-2F, a novel benzyl-furoquinoline with antiarrhythmic action, in rat aorta.
    Life sciences, 2010, Jun-05, Volume: 86, Issue:23-24

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2010
The role of calcium in modulating the reactivity of the smooth muscle cells during ischemia/reperfusion. Part 1.
    Postepy higieny i medycyny doswiadczalnej (Online), 2010, Apr-15, Volume: 64

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2010
Failure of Bay K 8644 to induce RhoA kinase-dependent calcium sensitization in rabbit blood vessels.
    British journal of pharmacology, 2010, Volume: 160, Issue:6

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2010
NS-398 (a selective cyclooxygenase-2 inhibitor) decreases agonist-induced contraction of the human ureter via calcium channel inhibition.
    Journal of endourology, 2010, Volume: 24, Issue:11

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2010
Ent-7α-acetoxytrachyloban-18-oic acid and ent-7α-hydroxytrachyloban-18-oic acid from Xylopia langsdorfiana A. St-Hil. & Tul. modulate K(+) and Ca(2+) channels to reduce cytosolic calcium concentration on guinea pig ileum.
    European journal of pharmacology, 2012, Mar-05, Volume: 678, Issue:1-3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2012
Identification and mechanosensitivity of viscerofugal neurons.
    Neuroscience, 2012, Dec-06, Volume: 225

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2012
L-type Ca(2+) channels, Ca(2+)-induced Ca(2+) release, and BK(Ca) channels in airway stretch-induced contraction.
    European journal of pharmacology, 2012, Dec-05, Volume: 696, Issue:1-3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2012
Ramipril treatment alters Ca(2+) and K(+) channels in small mesenteric arteries from Wistar-Kyoto and spontaneously hypertensive rats.
    American journal of hypertension, 2002, Volume: 15, Issue:10 Pt 1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2002
Effects of tetrandrine on smooth muscle contraction induced by mediators in pulmonary hypertension.
    Acta pharmacologica Sinica, 2002, Volume: 23, Issue:12

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3-Pyridinecarboxylic acid, 1,4-d

2002
The effects of paroxetine on rat isolated vas deferens.
    Pharmacological research, 2003, Volume: 48, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2003
L-type Ca2+ channels activation and contraction elicited by myricetin on vascular smooth muscles.
    Naunyn-Schmiedeberg's archives of pharmacology, 2003, Volume: 368, Issue:6

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2003
Heat-shock response is associated with enhanced contractility of vascular smooth muscle in isolated rat aorta.
    Naunyn-Schmiedeberg's archives of pharmacology, 2004, Volume: 369, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2004
Role of Ca2+ in vascular smooth muscle contractions induced by Phoneutria nigriventer spider venom.
    Toxicon : official journal of the International Society on Toxinology, 2004, Volume: 43, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2004
Regional differences in L-type Ca2+ channel expression in feline lower esophageal sphincter.
    American journal of physiology. Gastrointestinal and liver physiology, 2004, Volume: 287, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2004
L-type Ca(2+) channel expression along feline smooth muscle oesophagus.
    Neurogastroenterology and motility, 2004, Volume: 16, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2004
MaxiK channel-triggered negative feedback system is preserved in the urinary bladder smooth muscle from streptozotocin-induced diabetic rats.
    Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi, 2004, Volume: 40, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2004
Role of l-Ca(2+) channels in intestinal pacing in wild-type and W/W(V) mice.
    American journal of physiology. Gastrointestinal and liver physiology, 2005, Volume: 288, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2005
The responses to manipulation of extracellular and intracellular calcium are altered in the streptozotocin-diabetic rat colon and ileum.
    European journal of pharmacology, 2005, Feb-10, Volume: 509, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2005
Functional inhibition of intestinal and uterine muscles by non-permeant triphenylethylene derivatives.
    European journal of pharmacology, 2006, Feb-17, Volume: 532, Issue:1-2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2006
Vasomotor action of insulin on the rabbit normal cavernous smooth muscle.
    European journal of pharmacology, 2006, Apr-24, Volume: 536, Issue:1-2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2006
Muscarinic regulation of neonatal rat bladder spontaneous contractions.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2006, Volume: 291, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2006
Application of Fourier linear spectral analyses to the characterization of smooth muscle contractile signals.
    Journal of biochemical and biophysical methods, 2007, Aug-01, Volume: 70, Issue:5

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2007
Brazilein-induced contraction of rat arterial smooth muscle involves activation of Ca2+ entry and ROK, ERK pathways.
    European journal of pharmacology, 2008, Feb-12, Volume: 580, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2008
The vitamin D receptor agonist elocalcitol upregulates L-type calcium channel activity in human and rat bladder.
    American journal of physiology. Cell physiology, 2008, Volume: 294, Issue:5

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2008
An investigation of the actions of the calcium entry facilitator Bay K 8644 on the rat vas deferens.
    European journal of pharmacology, 1984, Sep-17, Volume: 104, Issue:3-4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1984
Agonist actions of Bay K 8644, a dihydropyridine derivative, on the voltage-dependent calcium influx in smooth muscle cells of the rabbit mesenteric artery.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 231, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1984
Calcium channel activation in vascular smooth muscle by BAY K 8644.
    Canadian journal of physiology and pharmacology, 1984, Volume: 62, Issue:11

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1984
Allosteric interactions at L-type calcium channels between FPL 64176 and the enantiomers of the dihydropyridine Bay K 8644.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 275, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1995
Ketamine inhibits contractile responses of intestinal smooth muscle by decreasing the influx of calcium through the L-type calcium channel.
    Acta anaesthesiologica Scandinavica, 1995, Volume: 39, Issue:6

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1995
Effects of nifedipine and Bay K 8644 on myotropic responses in aortic rings of pregnant rats.
    European journal of pharmacology, 1995, Jun-23, Volume: 280, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1995
Functional role of charybdotoxin-sensitive K+ channels in the resting state of cerebral, coronary and mesenteric arteries of the dog.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1993
Angiotensin-converting enzyme inhibition during development alters calcium regulation in adult hypertensive rats.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1993
Increased resting Ca2+ maintains the myogenic tone and activates K+ channels in arteries from young spontaneously hypertensive rats.
    European journal of pharmacology, 1993, Nov-15, Volume: 247, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1993
Rhythmic contractions of isolated small arteries from rat: role of calcium.
    Acta physiologica Scandinavica, 1993, Volume: 149, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1993
Pharmacologic properties of a novel Ca2+ entry blocker, AJ-2615, in vitro.
    Journal of cardiovascular pharmacology, 1993, Volume: 22, Issue:6

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1993
Role of L-type calcium channels on yohimbine-precipitated clonidine withdrawal in vivo and in vitro.
    Naunyn-Schmiedeberg's archives of pharmacology, 1993, Volume: 348, Issue:6

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1993
Mechanisms of myogenic enhancement by norepinephrine.
    The American journal of physiology, 1994, Volume: 266, Issue:2 Pt 2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1994
Role of Ca2+ in the vascular contraction caused by a thrombin receptor activating peptide.
    European journal of pharmacology, 1994, Apr-11, Volume: 256, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1994
The role of calcium and alpha-adrenoceptors in contractile response of chick expansor secundariorum muscle to field stimulation.
    General pharmacology, 1994, Volume: 25, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1994
Effects of nifedipine and Bay K 8644 on contractile activities in single skeletal muscle fibers of the frog.
    European journal of pharmacology, 1994, Apr-21, Volume: 256, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1994
Effect of Bay K 8644 and ryanodine on the refractory period, action potential and mechanical response of the guinea-pig ureter to electrical stimulation.
    Naunyn-Schmiedeberg's archives of pharmacology, 1994, Volume: 349, Issue:5

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1994
Signal transducing mechanisms coupled to histamine H3 receptors and alpha-2 adrenoceptors in the guinea pig duodenum: possible involvement of N-type Ca++ channels.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 270, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1994
Actions of abscisic acid and the analogue SD217595 on calcium mediated activity of rat vas deferens smooth muscle.
    General pharmacology, 1994, Volume: 25, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1994
A thiorphan-sensitive mechanism regulates the action of both exogenous and endogenous calcitonin gene-related peptide (CGRP) in the guinea-pig ureter.
    Regulatory peptides, 1994, May-26, Volume: 51, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1994
Effects of ramipril on contractile oscillations in arteries from genetically hypertensive rats.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 1994, Volume: 16, Issue:6

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1994
Contractile hyperreactivity and alteration of PKC activity in gastric fundus smooth muscle of diabetic rats.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 49, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5

1994
Effect of the calcium channel agonist Bay K8644 on mechanical and electrical responses of frog skeletal muscle.
    Canadian journal of physiology and pharmacology, 1994, Volume: 72, Issue:10

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1994
Functional evidence for a glibenclamide-sensitive K+ channel in rat ileal smooth muscle.
    European journal of pharmacology, 1994, Dec-27, Volume: 271, Issue:2-3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1994
Endothelin-induced facilitation of sympathetic neurotransmission to the rat vas deferens: effects of suramin.
    European journal of pharmacology, 1995, Jan-05, Volume: 272, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1995
Propagation of impulses in the guinea-pig ureter and its blockade by calcitonin gene-related peptide (CGRP).
    Naunyn-Schmiedeberg's archives of pharmacology, 1995, Volume: 351, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1995
Rabbit penile corpus cavernosum: electrical and mechanical activity of isolated strips.
    Investigative urology (Berlin, Germany), 1994, Volume: 5

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1994
A pharmacological analysis of calcium channels involved in phasic and tonic responses of the guinea-pig ureter to high potassium.
    Journal of autonomic pharmacology, 1995, Volume: 15, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1995
Effects of magnesium ions on detrusor contraction in rat.
    Urologia internationalis, 1995, Volume: 54, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1995
Calcium-and G-protein-related spasmolytic effects of nonsteroidal anti-inflammatory drugs on rat uterus contractions in vitro.
    Pharmacology, 1995, Volume: 50, Issue:5

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1995
Effect of Ca2+ agonist Bay K 8644 in human placental arteries.
    General pharmacology, 1995, Volume: 26, Issue:5

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1995
Relaxation of arterial smooth muscle by calcium sparks.
    Science (New York, N.Y.), 1995, Oct-27, Volume: 270, Issue:5236

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1995
Vasorelaxant effect of the analgesic clonixin on rat aorta.
    General pharmacology, 1995, Volume: 26, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1995
Influence of hormonal status in relaxant effect of diethylstilbestrol and nifedipine on isolated rat uterus contraction.
    General pharmacology, 1995, Volume: 26, Issue:6

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1995
Identification of a novel calcium antagonist binding site in rat brain by SR 33557.
    British journal of pharmacology, 1993, Volume: 108, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1993
Effects of halothane and isoflurane on cytosolic calcium ion concentrations and contraction in the vascular smooth muscle of the rat aorta.
    Anesthesiology, 1993, Volume: 78, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1993
The effect of calcium channel antagonists and BAY K 8644 on calcium fluxes of malignant hyperpyrexia-susceptible muscle.
    The International journal of biochemistry, 1993, Volume: 25, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1993
Effects of felodipine, nifedipine and verapamil on cytosolic Ca2+ and contraction in vascular smooth muscle.
    European journal of pharmacology, 1993, Mar-30, Volume: 234, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1993
Contractile responses to Bay K 8644 in rats with coarctation-induced hypertension.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1993, Volume: 203, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1993
Ca2+ regulation of the contractile apparatus in canine gastric smooth muscle.
    The Journal of physiology, 1993, Volume: 460

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1993
Effect of calcium agonists, BAY K 8644 and CGP 28392, on guinea pig airway smooth muscle function during development.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 265, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1993
Distinct pathways to refill ACh-sensitive internal Ca2+ stores in canine airway smooth muscle.
    The American journal of physiology, 1993, Volume: 265, Issue:1 Pt 1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1993
Age, endothelium and aortic reactivity to calcium in Wistar rat.
    Life sciences, 1993, Volume: 53, Issue:10

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1993
Ketamine relaxes rabbit femoral arteries by reducing [Ca2+]i and phospholipase C activity.
    European journal of pharmacology, 1993, Jun-04, Volume: 236, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1993
The topographical basis and frequency-dependence in the effect of different compounds on neurogenic contractions of the guinea-pig ileum.
    General physiology and biophysics, 1993, Volume: 12, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1993
Effect of TMB-8 on alpha-adrenoceptor agonist and KC1 induced-contractions in isolated rabbit aorta.
    General pharmacology, 1993, Volume: 24, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1993
Ca(2+)-channel blockade in rat thoracic aorta by crychine isolated from Cryptocarya chinensis Hemsl.
    The Journal of pharmacy and pharmacology, 1993, Volume: 45, Issue:8

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1993
Effect of nifedipine on cyclic GMP turnover in cultured coronary smooth muscle cells.
    Journal of cardiovascular pharmacology, 1995, Volume: 26, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1995
Effects of Bay K 8644 in aorta from spontaneously hypertensive and Wistar Kyoto rats of different ages.
    Journal of autonomic pharmacology, 1995, Volume: 15, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1995
Mechanisms involved in the relaxant effect of estrogens on rat aorta strips.
    Life sciences, 1996, Volume: 58, Issue:7

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1996
Augmented contractile function and abnormal Ca2+ handling in the aorta of Zucker obese rats with insulin resistance.
    Diabetes, 1996, Volume: 45 Suppl 3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1996
Endothelin-induced contractions in human placental blood vessels are enhanced in intrauterine growth retardation, and modulated by agents that regulate levels of intracellular calcium.
    Acta physiologica Scandinavica, 1995, Volume: 155, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1995
Relaxant effect of ketamine and its isomers on histamine-induced contraction of tracheal smooth muscle.
    British journal of anaesthesia, 1996, Volume: 76, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1996
A tyrosine kinase regulates alpha-adrenoceptor-stimulated contraction and phospholipase D activation in the rat aorta.
    European journal of pharmacology, 1996, Apr-29, Volume: 302, Issue:1-3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1996
Activation of delayed rectifier potassium channels in canine proximal colon by vasoactive intestinal peptide.
    The Journal of physiology, 1996, Jun-15, Volume: 493 ( Pt 3)

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1996
Inhibition by bosentan, an endothelin antagonist, of the hypersensitivity to Ca2+ channel activator evoked by salt-loading in basilar artery of stroke-prone spontaneously hypertensive rats.
    Life sciences, 1996, Volume: 59, Issue:16

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1996
Effect of the Ca(2+)-channel agonist Bay K 8644 on the contractile responses in human placental veins.
    Journal of autonomic pharmacology, 1996, Volume: 16, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1996
The role of sarcoplasmic reticulum and sarcoplasmic reticulum Ca2+-ATPase in the smooth muscle tone of the cat gastric fundus.
    Pflugers Archiv : European journal of physiology, 1996, Volume: 431, Issue:6

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1996
Subtype specificity of the ryanodine receptor for Ca2+ signal amplification in excitation-contraction coupling.
    The EMBO journal, 1996, Nov-15, Volume: 15, Issue:22

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1996
Canine bronchial sustained contraction in Ca2+-free medium: role of intracellular Ca2+.
    Canadian journal of physiology and pharmacology, 1996, Volume: 74, Issue:11

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1996
BAY K 8644 and ClO4- potentiate caffeine contracture without Ca2+ release channel activation.
    The American journal of physiology, 1997, Volume: 272, Issue:1 Pt 1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1997
Mode and mechanism of neurotensin action in rat proximal colon.
    European journal of pharmacology, 1997, Jan-29, Volume: 319, Issue:2-3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1997
A dihydropyridine-sensitive voltage-dependent calcium channel in the sarcolemmal membrane of crustacean muscle.
    The Journal of general physiology, 1997, Volume: 109, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1997
Frequency-dependent effects of Bay K 8644 on tetanic contractions of frog skeletal muscle.
    General pharmacology, 1997, Volume: 28, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1997
Prostaglandin E1 potentiation of the spontaneous phasic contraction of rat isolated portal vein by a cyclopiazonic acid-sensitive mechanism.
    British journal of pharmacology, 1997, Volume: 120, Issue:8

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1997
Involvement of both L- and N-type voltage-dependent Ca2+ channels in KCl- and veratridine-evoked transmitter release from non-adrenergic, non-cholinergic nerves in the rabbit iris sphincter muscle.
    Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 355, Issue:5

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1997
Pharmacological modulation of electromechanical coupling in the proximal and distal regions of the guinea-pig renal pelvis.
    Journal of autonomic pharmacology, 1997, Volume: 17, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1997
Effect of 17-beta estradiol in the rabbit: endothelium-dependent and -independent mechanisms of vascular relaxation.
    Journal of cardiovascular pharmacology, 1997, Volume: 30, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1997
Regulation of intracellular calcium in human esophageal smooth muscles.
    The American journal of physiology, 1997, Volume: 273, Issue:5

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1997
Bethanechol activates a post-receptor negative feedback mechanism in rabbit urinary bladder smooth muscle.
    The Journal of urology, 1998, Volume: 159, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1998
Long-lasting actions of Bay K 8644 on responses of guinea pig taenia coli.
    General pharmacology, 1998, Volume: 31, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1998
Contractile action of Mn2+ via Ca2+ channels activated by bay K 8644 in guinea-pig taenia coli.
    The Journal of pharmacy and pharmacology, 1998, Volume: 50, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1998
Involvement of intracellular Ca2+ stores in inhibitory effects of NO donor SIN-1 and cGMP.
    The American journal of physiology, 1998, Volume: 275, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1998
Calcium source diversity in canine lower esophageal sphincter muscle.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 287, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1998
Effects of magnesium on human umbilical arteries: role of intracellular calcium stores.
    Pharmacology, 1998, Volume: 57, Issue:6

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1998
Relationship between decreased function and O2 consumption caused by cyclic GMP in cardiac myocytes and L-type calcium channels.
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1998, Volume: 198, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1998
Myorelaxant activity of 2-t-butyl-4-methoxyphenol (BHA) in guinea pig gastric fundus.
    European journal of pharmacology, 1998, Oct-30, Volume: 360, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1998
Endothelin 1 action on isolated rat stomach and the role of calcium ions in ET 1 induced depolarization of smooth muscle cells BC3H1.
    Biochemistry and molecular biology international, 1998, Volume: 46, Issue:5

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1998
In vitro and in vivo vascular responses to the L-type calcium channel activator, Bay K 8644, in rats with cirrhosis.
    Journal of gastroenterology and hepatology, 1998, Volume: 13, Issue:12

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1998
The smooth muscle relaxant effects of venom from the inland taipan (Oxyuranus microlepidotus).
    Toxicon : official journal of the International Society on Toxinology, 1999, Volume: 37, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1999
Ca2+ buffering action of sarcoplasmic reticulum on Bay k 8644-induced Ca2+ influx in rat femoral arterial smooth muscle.
    European journal of pharmacology, 1999, Jan-29, Volume: 366, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1999
Effects of IBMX on norepinephrine-induced vasoconstriction in small mesenteric arteries.
    The American journal of physiology, 1999, Volume: 276, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifl

1999
[Pre- and postsynaptic action of the ATP-dependent K+-channel-(K+ATP)-opener pinacidil in rabbit pulmonary artery].
    Acta pharmaceutica Hungarica, 1999, Volume: 69, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1999
Tight coupling between the rate of rise of Ca2+ transient and peak twitch contraction in guinea-pig papillary muscle.
    European journal of pharmacology, 1999, Jul-21, Volume: 377, Issue:2-3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1999
Influence of age on contractile response to insulin-like growth factor 1 in ventricular myocytes from spontaneously hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 34, Issue:6

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1999
Silent calcium channels in skeletal muscle fibers of the crustacean Atya lanipes.
    The Journal of membrane biology, 2000, Jan-01, Volume: 173, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2000
Impairment of Ca(2+) mobilization in circular muscle cells of the inflamed colon.
    American journal of physiology. Gastrointestinal and liver physiology, 2000, Volume: 278, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2000
Cardiac excitation-contraction coupling in the portal hypertensive rat.
    American journal of physiology. Gastrointestinal and liver physiology, 2000, Volume: 279, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2000
Effects of (+) and (-) enantiomers of calcium channel agonist, Bay K 8644, on mechanical and electrical responses of frog skeletal muscle.
    Canadian journal of physiology and pharmacology, 2000, Volume: 78, Issue:8

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2000
Changes of the potassium currents in rat aortic smooth muscle cells during postnatal development.
    Pflugers Archiv : European journal of physiology, 2000, Volume: 441, Issue:2-3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2000
Neural regulation of in vitro giant contractions in the rat colon.
    American journal of physiology. Gastrointestinal and liver physiology, 2001, Volume: 281, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2001
Calcium buffering of resting, voltage-dependent Ca2+ influx by sarcoplasmic reticulum in femoral arteries from spontaneously hypertensive rats at prehypertensive stage.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2001, Volume: 24, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2001
Diminished inibitory action of ethanol on the contraction of gallbladder isolated from chronically ethanol-fed Guinea pigs.
    Pharmacology, 2002, Volume: 65, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2002
Smooth muscle in the annulus fibrosus of the tympanic membrane: physiological effects on sound transmission in the gerbil.
    Hearing research, 2002, Volume: 164, Issue:1-2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2002
Inhibitory effects of tetrandrine on Bay k 8644-stimulated contraction of isolated rabbit aortic strips.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1992, Volume: 13, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1992
Mechanisms of neurotensin-induced inhibition in rat ileal smooth muscle.
    The American journal of physiology, 1992, Volume: 263, Issue:5 Pt 1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1992
Clinical potency of calcium channel blockers in asthma may be related to their inhibition of receptor-mediated phasic responses in vitro.
    Life sciences, 1992, Volume: 51, Issue:26

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1992
The long-term inhibitory effect of a Ca2+ channel blocker, nisoldipine, on cytosolic Ca2+ and contraction in vascular smooth muscle.
    European journal of pharmacology, 1992, Nov-17, Volume: 223, Issue:2-3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1992
Calcium channel blocker-like action of reserpine in smooth muscle.
    Japanese journal of pharmacology, 1992, Volume: 60, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1992
Selectivity of Ca2+ channel blockers in inhibiting muscular and nerve activities in isolated colon.
    British journal of pharmacology, 1991, Volume: 102, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1991
Comparison of Bay K 8644, nitrendipine and atropine on spontaneous and pelvic-nerve-induced bladder contractions on rat bladder in vivo.
    Urological research, 1992, Volume: 20, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1992
Pharmacologic and radioligand binding studies of 1,4-dihydropyridines in rat cardiac and vascular preparations: stereoselectivity and voltage dependence of antagonist and activator interactions.
    Molecular pharmacology, 1992, Volume: 41, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1992
L-type Ca2+ channel desensitization by F- reduces PhE-induced increase in [Ca2+]i but not stress.
    The American journal of physiology, 1992, Volume: 262, Issue:3 Pt 1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1992
Effect of Bay K 8644 on the magnitude of isoflurane and halothane contracture of skeletal muscle from patients susceptible to malignant hyperthermia.
    Anesthesiology, 1992, Volume: 76, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1992
Calcium channel agonist/antagonist effects on cholinergic stimulation of the diabetic rat bladder.
    Pharmacology, 1992, Volume: 44, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1992
Dual effects of endothelins -1, -2 and -3 on guinea pig field-stimulated ileum: possible mediation by two receptors coupled to pertussis toxin-insensitive mechanisms.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 261, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1992
Effect of epithelium removal and of enkephalin inhibition on the bronchoconstrictor response to three endothelins of the human isolated bronchus.
    European journal of pharmacology, 1992, Jan-21, Volume: 210, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1992
Paradoxical decrease in cytosolic calcium with increasing depolarization by potassium in guinea-pig mesotubarium smooth muscle.
    Pflugers Archiv : European journal of physiology, 1992, Volume: 420, Issue:5-6

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1992
Halothane relaxes preconstricted small and medium isolated porcine coronary artery segments more than isoflurane.
    Anesthesia and analgesia, 1992, Volume: 75, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1992
Vasorelaxing effect in rat thoracic aorta caused by fraxinellone and dictamine isolated from the Chinese herb Dictamnus dasycarpus Turcz: comparison with cromakalim and Ca2+ channel blockers.
    Naunyn-Schmiedeberg's archives of pharmacology, 1992, Volume: 345, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1992
Positive inotropic and negative chronotropic effects of (-)-cis-diltiazem in rat isolated atria.
    British journal of pharmacology, 1992, Volume: 105, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1992
Carbachol modulates voltage sensitivity of calcium channels in bronchial smooth muscle of rats.
    The American journal of physiology, 1992, Volume: 263, Issue:1 Pt 1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1992
Vasoconstrictive responses elicited by endothelin in bovine cerebral arteries.
    General pharmacology, 1992, Volume: 23, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1992
Na+/Ca2+ exchange mediation in the ouabain-induced contraction in human placental vessels.
    General pharmacology, 1992, Volume: 23, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1992
Partial inhibition of skeletal muscle contraction by dantrolene sodium and its modification with perchlorate and Bay K 8644.
    Canadian journal of physiology and pharmacology, 1992, Volume: 70, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1992
Effect of the phospholipase A2 inhibitors quinacrine and 7,7-dimethyleicosadienoic acid in isolated globally ischemic rat hearts.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 262, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1992
Excitation-contraction coupling in canine tracheal smooth muscle cells.
    Advances in experimental medicine and biology, 1992, Volume: 311

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1992
Silver-induced frog skeletal muscle contraction and its modulation by calcium antagonists nifedipine and felodipine and calcium agonist Bay K 8644.
    General pharmacology, 1992, Volume: 23, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1992
Effects of endothelin on the portal vein from spontaneously hypertensive and Wistar Kyoto rats.
    General pharmacology, 1990, Volume: 21, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1990
Effects of calcium channel activators on contractile behavior in vascular smooth muscle.
    Progress in clinical and biological research, 1990, Volume: 327

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1990
Light-induced relaxation of smooth muscle after treatment with BAY K 8644 is related to release of nitric oxide.
    Progress in clinical and biological research, 1990, Volume: 327

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1990
Some pharmacological characteristics of the guinea pig ileum opioid system activated by cholecystokinin.
    Neuropharmacology, 1990, Volume: 29, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1990
Bicarbonate-dependent action of Bay K 8644 in the smooth muscle of the rat vas deferens.
    Japanese journal of pharmacology, 1990, Volume: 52, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1990
Reproducible withdrawal contractions of isolated guinea-pig ileum after brief morphine exposure: effects of clonidine and nifedipine.
    The Journal of pharmacy and pharmacology, 1990, Volume: 42, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1990
Vascular contraction induced by activation of membrane calcium ion channels is enhanced in streptozotocin-diabetes.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 253, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1990
Comparative behavioral, neurochemical and pharmacological activities of dihydropyridine calcium channel activating drugs.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 253, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1990
Increased calcium sensitivity in isolated resistance arteries from spontaneously hypertensive rats: effects of dihydropyridines.
    European journal of pharmacology, 1990, Apr-25, Volume: 179, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1990
Tissue selectivity and calcium dependence of contractile responses to endothelin.
    Journal of cardiovascular pharmacology, 1990, Volume: 15, Issue:6

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1990
Contractile activity of three endothelins (ET-1, ET-2 and ET-3) on the human isolated bronchus.
    British journal of pharmacology, 1990, Volume: 100, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1990
Interactions of palmitoyl carnitine with the endothelium in rat aorta.
    British journal of pharmacology, 1990, Volume: 100, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1990
Antagonism by nifedipine of contraction and Ca2(+)-influx evoked by ATP in guinea-pig urinary bladder.
    British journal of pharmacology, 1990, Volume: 100, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1990
Differences in vascular responses to vasoactive agents of basilar artery and aorta from rabbits with alloxan-induced diabetes.
    Canadian journal of physiology and pharmacology, 1990, Volume: 68, Issue:7

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1990
Evidence for two calcium-dependent potassium conductances in lizard motor nerve terminals.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1990, Volume: 10, Issue:8

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1990
Dihydropyridine calcium channel antagonists block and agonists potentiate high potassium contractures but not twitches in frog skeletal muscle.
    The Japanese journal of physiology, 1990, Volume: 40, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1990
Increased vascular reactivity to Bay K 8644 in genetic hypertension.
    Pharmacology, 1990, Volume: 41, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1990
Pharmacological dissection of Ca2+ channels in the rat aorta by Ca2+ entry modulators.
    Pharmacology, 1990, Volume: 40, Issue:6

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1990
Inhibitory effect of 2,3-dibenzylbutane-1,4-diol; a mammalian lignan, on the CA2+ channel in rabbit femoral artery.
    Research communications in chemical pathology and pharmacology, 1990, Volume: 69, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1990
Effects of endothelins on nerve-mediated contractions of the mouse vas deferens.
    Life sciences, 1990, Volume: 47, Issue:17

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1990
Pharmacological studies of human erectile tissue: characteristics of spontaneous contractions and alterations in alpha-adrenoceptor responsiveness with age and disease in isolated tissues.
    British journal of pharmacology, 1990, Volume: 101, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1990
Dihydropyridine-sensitive single calcium channels in airway smooth muscle cells.
    The American journal of physiology, 1990, Volume: 259, Issue:6 Pt 1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1990
Use of the calcium agonist BAY K 8644 for in vitro diagnosis of susceptibility to malignant hyperthermia.
    British journal of anaesthesia, 1990, Volume: 65, Issue:6

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1990
Calcium dependence of the contraction produced by endothelin (ET-1) in isolated guinea-pig trachea.
    European journal of pharmacology, 1990, Oct-23, Volume: 187, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1990
Endotoxin-induced impairment of vascular smooth muscle contractions elicited by different mechanisms.
    European journal of pharmacology, 1990, Nov-06, Volume: 190, Issue:1-2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1990
Potentiating effect of daunorubicin on vasocontractile responses to KCl and BAY K 8644 in rat aorta.
    The Journal of pharmacy and pharmacology, 1990, Volume: 42, Issue:10

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1990
Differential effects of calcium antagonists and Bay K 8644 on contractile responses to exogenous noradrenaline and adrenergic nerve stimulation in the rabbit ear artery.
    British journal of pharmacology, 1990, Volume: 101, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1990
Deuterium oxide reduces agonist and depolarization-induced contraction of rat aortic rings.
    Canadian journal of physiology and pharmacology, 1990, Volume: 68, Issue:12

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1990
Simultaneous measurement of membrane potential, cytosolic Ca2+, and tension in intact smooth muscles.
    The American journal of physiology, 1991, Volume: 260, Issue:5 Pt 1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1991
Effects of a novel smooth muscle relaxant, KT-362, on contraction and cytosolic Ca2+ level in the rat aorta.
    British journal of pharmacology, 1991, Volume: 102, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1991
The inhibitory action of okadaic acid on mechanical responses in guinea-pig vas deferens.
    European journal of pharmacology, 1991, Jan-25, Volume: 193, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1991
Comparison of the effects of endothelin-1 and Bay k 8644 on twitch contractions of the field-stimulated rat vas deferens.
    European journal of pharmacology, 1991, Feb-14, Volume: 193, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1991
Contractions of dysgenic skeletal muscle triggered by a potentiated, endogenous calcium current.
    The Journal of general physiology, 1991, Volume: 97, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1991
Low pH-induced release of calcitonin gene-related peptide from capsaicin-sensitive sensory nerves: mechanism of action and biological response.
    Neuroscience, 1991, Volume: 41, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5

1991
Acetylcholine Ca2+ stores refilling directly involves a dihydropyridine-sensitive channel in dog trachea.
    The American journal of physiology, 1991, Volume: 261, Issue:3 Pt 1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1991
Effects of calcium-free solution, calcium antagonists, and the calcium agonist BAY K 8644 on mechanical responses of skeletal muscle from patients susceptible to malignant hyperthermia.
    Anesthesiology, 1991, Volume: 75, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1991
BAY K 8644 and nifedipine alter halothane but not caffeine contractures of malignant hyperthermic muscle fibers.
    The American journal of physiology, 1991, Volume: 261, Issue:4 Pt 2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1991
Effects of the calcium channel agonist, Bay K 8644, on the mechanical output of skeletal muscle fibers.
    General pharmacology, 1991, Volume: 22, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1991
Effects of BAY K 8644, nifedipine, and low Ca2+ on halothane and caffeine potentiation.
    Journal of applied physiology (Bethesda, Md. : 1985), 1991, Volume: 71, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1991
Carbachol-induced nonspecific desensitization in guinea-pig ileum.
    Naunyn-Schmiedeberg's archives of pharmacology, 1991, Volume: 343, Issue:6

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1991
Use-dependent decline in rat aorta sensitivity to contraction by potassium.
    Canadian journal of physiology and pharmacology, 1991, Volume: 69, Issue:7

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1991
Omega conotoxin and prejunctional modulation of the biphasic response of the rat isolated urinary bladder to single pulse electrical field stimulation.
    Journal of autonomic pharmacology, 1991, Volume: 11, Issue:5

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1991
Multiple effects of BAY K 8644 and nifedipine on isolated diaphragmatic fibers in vitro.
    Journal of applied physiology (Bethesda, Md. : 1985), 1991, Volume: 71, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1991
The dual effect of BAY K 8644 on excitation-contraction coupling in gastric smooth muscle.
    General pharmacology, 1991, Volume: 22, Issue:5

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1991
Sialic acid removal modulates the myocardial and vascular activity of calcium channel ligands.
    Biochemical pharmacology, 1991, Dec-11, Volume: 42 Suppl

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1991
Neurogenic function of the diabetic rat bladder: alteration by calcium channel effectors.
    Pharmacology, 1991, Volume: 43, Issue:5

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1991
Indolizinsulphones. A class of blockers with dual but discriminative effects on L-type Ca2+ channel activity and excitation-contraction coupling in skeletal muscle.
    Pflugers Archiv : European journal of physiology, 1991, Volume: 419, Issue:6

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1991
Sodium pump activity and contractile effect of ouabain in human placental veins.
    European journal of pharmacology, 1991, Aug-16, Volume: 201, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1991
Calcium antagonistic properties of the sesquiterpene T-cadinol: a comparison with nimodipine in the isolated rat aorta.
    Pharmacology & toxicology, 1991, Volume: 69, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1991
Contraction of vascular smooth muscle induced by phorbol 12,13 dibutyrate in human and rat pulmonary arteries.
    British journal of pharmacology, 1991, Volume: 104, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1991
Phorbol esters induce oscillatory contractions of intestinal smooth muscles.
    European journal of pharmacology, 1991, Aug-29, Volume: 201, Issue:2-3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1991
Synergistic coronary vasoconstriction produced by endothelin-1 in combination with 5-hydroxytryptamine.
    Journal of cardiovascular pharmacology, 1991, Volume: 17 Suppl 7

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1991
Nitrendipine potentiates Bay k 8644-induced contraction of isolated porcine coronary artery: evidence for functionally distinct dihydropyridine receptor subtypes.
    Biochemical and biophysical research communications, 1985, May-16, Volume: 128, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1985
Excitation contraction coupling in skeletal muscle: evidence for a role of slow Ca2+ channels using Ca2+ channel activators and inhibitors in the dihydropyridine series.
    Biochemical and biophysical research communications, 1985, Jun-28, Volume: 129, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1985
The effect of Bay K 8644 on contraction mediated by alpha-adrenoceptors in the rat saphenous vein.
    British journal of pharmacology, 1985, Volume: 85, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1985
Comparison of effects of a new dihydropyridine, Bay K 8644, and nifedipine on spontaneous mechanical activity in rat portal vein.
    British journal of pharmacology, 1985, Volume: 85, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1985
Positive inotropic effect of Bay K 8644: cAMP-independence and lack of inhibitory effect of adenosine.
    Naunyn-Schmiedeberg's archives of pharmacology, 1985, Volume: 329, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1985
The effects of BAY-K-8644 on the contraction of cat middle cerebral and femoral arteries.
    Biochemical pharmacology, 1985, Sep-01, Volume: 34, Issue:17

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1985
Further examination of the inhibitory actions of alpha 1-adrenoceptor agonists in rat vas deferens.
    European journal of pharmacology, 1985, Jul-17, Volume: 113, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1985
The effect of the calcium channel agonist, Bay K-8644 on human vascular smooth muscle.
    European journal of pharmacology, 1985, Jul-31, Volume: 113, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1985
Inhibitory effect of adenosine on electrically evoked contractions in the rat vas deferens: calcium dependence.
    Neuroscience letters, 1985, Aug-16, Volume: 59, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1985
The effects of the dihydropyridine Bay K 8644 in guinea-pig isolated trachealis.
    British journal of pharmacology, 1985, Volume: 86, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1985
Plasma membrane calcium flux, protein kinase C activation and smooth muscle contraction.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1985
Activation of tracheal smooth muscle contraction: synergism between Ca2+ and activators of protein kinase C.
    Proceedings of the National Academy of Sciences of the United States of America, 1985, Volume: 82, Issue:24

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1985
A comparison of effects of BAY K 8644 and CGP 28392, dihydropyridines with Ca agonistic properties, on spontaneous mechanical activity in rat portal vein: modification of effect by ultraviolet radiation.
    Acta pharmacologica et toxicologica, 1985, Volume: 57, Issue:5

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1985
[Synergism of the calcium reversal phenomenon of potassium depolarizing in the rat uterine muscle by Bay k-8644, a calcium agonist].
    Nihon Heikatsukin Gakkai zasshi, 1985, Volume: 21, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1985
The facilitative actions of Bay K 8644 on norepinephrine and KCl-induced contractures of rabbit aortic rings.
    Life sciences, 1986, Feb-24, Volume: 38, Issue:8

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1986
Effects of Bay K 8644 and nifedipine on femoral arteries of spontaneously hypertensive rats.
    British journal of pharmacology, 1986, Volume: 88, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1986
Effects of Bay K 8644 on contraction of the human isolated bronchus and guinea-pig isolated trachea.
    British journal of pharmacology, 1986, Volume: 88, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1986
The effects of Bay K 8644 and nifedipine on the neural responses of the rabbit ear artery.
    British journal of pharmacology, 1986, Volume: 88, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1986
[Effects of a new 1,4-dihydropyridine, Bay K 8644, on smooth muscle organs isolated from the guinea pig].
    Bollettino della Societa italiana di biologia sperimentale, 1986, Apr-30, Volume: 62, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1986
Mechanism of barium-induced contraction in the vascular smooth muscle of rabbit aorta.
    British journal of pharmacology, 1986, Volume: 88, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1986
Involvement of calcium channels in the contractile activity of neurotensin but not acetylcholine: studies with calcium channel blockers and Bay K 8644 on the rat fundus.
    British journal of pharmacology, 1986, Volume: 88, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1986
o-Isothiocyanate dihydropyridine (oNCS-DHP), a long-acting, reversible inhibitor of the Ca++ channel.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 238, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1986
The effect of Bay K 8644 on angiotensin II-induced contractions of rabbit aortic strips.
    European journal of pharmacology, 1986, Jul-15, Volume: 126, Issue:1-2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1986
Pharmacologic and radioligand binding analysis of the actions of 1,4-dihydropyridine activator-antagonist pairs in smooth muscle.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1986
Contractile effects of Bay k 8644, a dihydropyridine calcium agonist, on isolated femoral arteries from spontaneously hypertensive rats.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1986
Bay K 8644 and acetylcholine: different interaction with calcium ions in the rat duodenal muscle.
    Pharmacology, 1986, Volume: 33, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1986
The calcium channel agonist BAY K8644 enhances the responsiveness of human airway muscle to KCl and histamine but not to carbachol.
    The American review of respiratory disease, 1987, Volume: 135, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1987
Calcium antagonists inhibit positive chronotropic responses to alpha 1-adrenoceptor activation in rat isolated atria.
    European journal of pharmacology, 1987, Jan-13, Volume: 133, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1987
Ca2+ channel ligand sensitive responses to the phorbol ester 12-O-tetradecanoylphorbol 13-acetate in vascular smooth muscle.
    Canadian journal of physiology and pharmacology, 1986, Volume: 64, Issue:12

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1986
Effects of calcium, calcium channel blockers and Bay K 8644 on contractions induced by muscarinic receptor stimulation of isolated bladder muscle from rabbit and man.
    The Journal of urology, 1987, Volume: 137, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1987
Benzodiazepine interactions at neuronal and smooth muscle Ca2+ channels.
    European journal of pharmacology, 1987, Feb-10, Volume: 134, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1987
Demonstration of alpha 2-adrenoceptor-mediated contraction in the isolated canine saphenous artery treated with Bay K 8644.
    European journal of pharmacology, 1987, Mar-03, Volume: 135, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1987
Role of endothelium in magnesium-induced relaxation of rat aorta.
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1987, Volume: 187, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1987
Effects of norepinephrine on BAY K-8644-induced contraction in porcine coronary artery.
    Archives internationales de pharmacodynamie et de therapie, 1987, Volume: 285, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1987
Effects of dihydropyridines on stress, myosin phosphorylation, and V0 in smooth muscle.
    The American journal of physiology, 1987, Volume: 252, Issue:6 Pt 2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1987
Measurement of cytoplasmic free Ca2+ concentration in rabbit aorta using the photoprotein, aequorin. Effect of atrial natriuretic peptide on agonist-induced Ca2+ signal generation.
    The Journal of clinical investigation, 1987, Volume: 80, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1987
Dihydropyridine-sensitive Ca2+ channels and inositol phospholipid metabolism in ethanol physical dependence.
    Annals of the New York Academy of Sciences, 1987, Volume: 492

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1987
Effects of Bay K 8644 on the electrically evoked and KCl-evoked norepinephrine release and the corresponding contraction in isolated canine saphenous veins.
    Japanese journal of pharmacology, 1987, Volume: 43, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1987
[Two components of calcium-dependent potassium permeability coexist in the membrane of frog skeletal muscle].
    Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie, 1987, Volume: 305, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1987
Opposite effects of Bay k 8644 and nicardipine on the inhibitory effect of Ca2+ on rat myometrium.
    European journal of pharmacology, 1987, Aug-21, Volume: 140, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1987
Vascular responses to agonists in rat mesenteric artery from diabetic rats.
    Canadian journal of physiology and pharmacology, 1987, Volume: 65, Issue:7

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1987
Decreased contractile response after exposure of the rat aorta to Db cAMP or IBMX.
    Biomedica biochimica acta, 1987, Volume: 46, Issue:8-9

    Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifl

1987
Effects of a phorbol ester on rat aortic contraction and calcium influx in the presence and absence of BAY k 8644.
    European journal of pharmacology, 1987, Dec-01, Volume: 144, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1987
Interaction between Bay-K-8644 and various relaxant agents on K+-depolarized contracture of guinea pig taenia coli.
    General pharmacology, 1988, Volume: 19, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1988
Influence of endothelium on the response to calcium agonists, calcium, potassium and noradrenaline in rat aorta.
    Pharmacology & toxicology, 1988, Volume: 62, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1988
Inhibitory effects of caffeine on contractions and calcium movement in vascular and intestinal smooth muscle.
    British journal of pharmacology, 1988, Volume: 93, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1988
Nifedipine and BAY K inhibit contraction independently from their action on calcium channels.
    Biochemical and biophysical research communications, 1988, May-16, Volume: 152, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1988
Sites of action of dihydropyridine drugs in the mouse hemidiaphragm muscle.
    European journal of pharmacology, 1988, Mar-29, Volume: 148, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1988
Is airway hyperresponsiveness a smooth muscle abnormality?
    Progress in clinical and biological research, 1988, Volume: 263

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1988
Altered effect of BAY K 8644 after exposure of the rat aorta to IBMX or Db cAMP.
    Biomedica biochimica acta, 1988, Volume: 47, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifl

1988
Changes in cytosolic calcium level in vascular smooth muscle strip measured simultaneously with contraction using fluorescent calcium indicator fura 2.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1988
Effects of extracellular calcium concentration and dihydropyridines on contraction in mammalian skeletal muscle.
    The Journal of physiology, 1988, Volume: 399

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1988
Bay K 8644-like contractile effects of a peptide isolated from spontaneously hypertensive rats.
    Canadian journal of physiology and pharmacology, 1988, Volume: 66, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1988
Interactions between phorbol esters and agents which increase cytosolic calcium in the guinea pig parenchymal strip: direct and indirect effects on the contractile response.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 247, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1988
Endothelin and Ca++ agonist Bay K 8644: different vasoconstrictive properties.
    Biochemical and biophysical research communications, 1988, Oct-14, Volume: 156, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1988
Differential effects of calcium channel blockers and stimulants on morphine withdrawal in vitro.
    European journal of pharmacology, 1988, Jul-26, Volume: 152, Issue:1-2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1988
Dependence of stress on cross-bridge phosphorylation in vascular smooth muscle.
    The American journal of physiology, 1989, Volume: 256, Issue:1 Pt 1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1989
Mechanisms of increased responses of the aorta to alpha-adrenoceptor agonists in streptozotocin-induced diabetic rats.
    Journal of pharmacobio-dynamics, 1988, Volume: 11, Issue:10

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1988
Tetrodotoxin-resistant contractions induced by electrical stimulation of bladder muscle from man, rabbit and rat.
    Acta physiologica Scandinavica, 1988, Volume: 132, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1988
Potentiation by neuropeptide Y of vasoconstriction in rat resistance arteries.
    British journal of pharmacology, 1988, Volume: 95, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1988
Voltage and time dependency of calcium mediated phasic and tonic responses in rat vas deferens smooth muscle--the effect of some calcium agonist and antagonist agents.
    General pharmacology, 1988, Volume: 19, Issue:6

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1988
Interactions of calcium antagonists and the calcium channel agonist Bay K 8644 on neurotransmission of the mouse isolated vas deferens.
    British journal of pharmacology, 1989, Volume: 96, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1989
Stimulation of voltage-dependent contractions by calcium channel activator Bay K 8644 in the human upper urinary tract in vitro.
    The Journal of urology, 1989, Volume: 141, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1989
Inhibition of the oxygen-induced contraction of the isolated human umbilical artery by indomethacin, flurbiprofen, aspirin and drugs modifying Ca2+ disposition.
    Prostaglandins, 1988, Volume: 36, Issue:5

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1988
Endothelin increases single-channel calcium currents in coronary arterial smooth muscle cells.
    FEBS letters, 1989, Apr-10, Volume: 247, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1989
Bay K 8644-induced potentiation of the contractile response of rabbit iliac artery to caffeine in a Ca2+-free medium.
    General pharmacology, 1989, Volume: 20, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1989
Effects of verapamil and BAY K 8644 on the hypoxic contraction of the isolated human pulmonary artery.
    The Tohoku journal of experimental medicine, 1989, Volume: 157, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1989
Characterization of the effects of AHN 086, an irreversible ligand of "peripheral" benzodiazepine receptors, on contraction in guinea-pig atrial and ileal longitudinal smooth muscle.
    Canadian journal of physiology and pharmacology, 1989, Volume: 67, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1989
Assessment in pig coronary artery of long-lasting and potent calcium antagonistic actions of the novel dihydropyridine derivative mepirodipine hydrochloride.
    Arzneimittel-Forschung, 1989, Volume: 39, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1989
Effects of calcium-entry modulators on the biphasic neurogenic contractions in the circular muscle of guinea pig vas deferens.
    Japanese journal of pharmacology, 1989, Volume: 49, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1989
Differential antagonism of the negative inotropic effect of gentamicin by calcium ions, Bay K 8644 and isoprenaline in canine ventricular muscle: comparison with cobalt ions.
    British journal of pharmacology, 1989, Volume: 96, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1989
Effects of atrial natriuretic factor (ANF) on phenylephrine-triggered intra- and extracellular calcium dependent contraction in rat aorta.
    Journal of autonomic pharmacology, 1989, Volume: 9, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1989
Pharmacology of endothelin-1 in isolated vessels: effect of nicardipine, methylene blue, hemoglobin, and gossypol.
    Journal of cardiovascular pharmacology, 1989, Volume: 13 Suppl 5

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1989
Endothelin-1-induced vascular contractions: interactions with drugs affecting the calcium channel.
    Journal of cardiovascular pharmacology, 1989, Volume: 13 Suppl 5

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1989
Inhibition by prostaglandin E2 of neurotransmission in rabbit but not human bronchus--a calcium-related mechanism?
    Prostaglandins, 1989, Volume: 37, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1989
Bay K 8644 induced necrosis in murine skeletal muscle in vitro: myofibre breakdown precedes significant alterations of intracellular [Ca] or pH.
    Acta neuropathologica, 1989, Volume: 77, Issue:6

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1989
Endothelin-1 contracts isolated vessels independently of dihydropyridine-sensitive Ca2+ channel activation.
    European journal of pharmacology, 1989, Jun-20, Volume: 165, Issue:2-3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1989
Sensitization alters contractile responses and calcium influx in human airway smooth muscle.
    The Journal of allergy and clinical immunology, 1989, Volume: 84, Issue:4 Pt 1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1989
Vascular smooth muscle function in rats with acute renal failure.
    The Journal of pharmacy and pharmacology, 1989, Volume: 41, Issue:8

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1989
Appearance of the slow Ca conductance in myotubes from mutant mice with "muscular dysgenesis".
    Pflugers Archiv : European journal of physiology, 1989, Volume: 414, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1989
Regulation by calcium and myosin phosphorylation of the development and maintenance of stress in vascular smooth muscle.
    Progress in clinical and biological research, 1989, Volume: 315

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1989
Slow onset of and recovery from Ca blocking action of benidipine in rat aorta and portal vein.
    Japanese journal of pharmacology, 1989, Volume: 51, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1989
Endothelin-induced contractions of tracheal smooth muscle and identification of specific endothelin binding sites in the trachea of the rat.
    British journal of pharmacology, 1989, Volume: 98, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1989
Outward potassium currents in freshly isolated smooth muscle cell of dog coronary arteries.
    Circulation research, 1989, Volume: 65, Issue:6

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1989
The selective potentiation of noradrenaline-induced tone by Bay K 8644 in the rabbit basilar artery.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1989, Volume: 9, Issue:6

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1989
Protein kinase C potentiates stretch-induced cerebral artery tone by increasing intracellular sensitivity to Ca2+.
    Biochemical and biophysical research communications, 1989, Nov-30, Volume: 165, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1989
Multiple sources of calcium for contraction of the human urinary bladder muscle.
    British journal of pharmacology, 1989, Volume: 98, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1989
Effects of the Ca agonists Bay K 8644 and CGP 28392 on vascular smooth muscle tone.
    General pharmacology, 1989, Volume: 20, Issue:6

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1989
Dihydropyridine inhibition of single calcium channels and contraction in rabbit mesenteric artery depends on voltage.
    The Journal of physiology, 1989, Volume: 412

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1989
[Effects of BAY K 8644, a slow calcium channel agonist, on muscle contraction induced by halothane in sensitive subjects with malignant hyperthermia].
    Annales francaises d'anesthesie et de reanimation, 1989, Volume: 8 Suppl

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1989
Potentiating effect of Bay K 8644 on the noradrenaline-induced contraction in rabbit renal and femoral arteries.
    General pharmacology, 1989, Volume: 20, Issue:5

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1989
Further investigation of a potential calcium channel modulator isolated from rat erythrocytes.
    Canadian journal of physiology and pharmacology, 1989, Volume: 67, Issue:10

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1989
Potentiation by treatment with reserpine of alpha 2-adrenoceptor-mediated contractions of rat tail artery.
    European journal of pharmacology, 1989, Nov-14, Volume: 171, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1989
(-)-Bay K 8644 liberates a contractant factor from the endothelium of the rat aorta.
    Fundamental & clinical pharmacology, 1989, Volume: 3, Issue:6

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1989
Effects of Ca2+ antagonists and K+-channel activators on K+-induced contractions in the rat aorta.
    Journal of autonomic pharmacology, 1989, Volume: 9, Issue:5

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1989
Relationship between myoplasmic calcium transients and calcium currents in frog skeletal muscle.
    The Journal of general physiology, 1989, Volume: 94, Issue:6

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1989
Comparison of the effects of calcium and the calcium channel stimulant Bay k 8644 on neomycin-induced neuromuscular blockade.
    Pharmacology & toxicology, 1989, Volume: 65, Issue:5

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1989
Nicardipine inhibits axon conduction but causes dual changes of acetylcholine release in the mouse motor nerve.
    Canadian journal of physiology and pharmacology, 1989, Volume: 67, Issue:12

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1989
Amplifying effects of several vasoconstrictor agents of alpha 1-adrenoceptor-mediated contraction of isolated thoracic aortae of the guinea pig.
    Pharmacology, 1989, Volume: 39, Issue:6

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1989
Role of endothelium in the contractile response of rat aorta to alpha-adrenoceptor agonists.
    Clinical science (London, England : 1979), 1985, Volume: 68 Suppl 10

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1985
A novel 1,4 dihydropyridine, BAY K 8644, with contractile effects on vascular smooth muscle.
    Acta pharmacologica et toxicologica, 1985, Volume: 56, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1985
Competitive interactions between Bay K 8644 and nifedipine in K+ depolarized smooth muscle: a passive role for Ca2+?
    Naunyn-Schmiedeberg's archives of pharmacology, 1985, Volume: 328, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1985