Page last updated: 2024-10-23

bay-k-8644 and Cardiovascular Stroke

bay-k-8644 has been researched along with Cardiovascular Stroke in 2 studies

3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester: A dihydropyridine derivative, which, in contrast to NIFEDIPINE, functions as a calcium channel agonist. The compound facilitates Ca2+ influx through partially activated voltage-dependent Ca2+ channels, thereby causing vasoconstrictor and positive inotropic effects. It is used primarily as a research tool.
Bay-K-8644 : A racemate comprising equimolar amounts of (R)- and (S)-Bay-K-8644
methyl 2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3-carboxylate : A pentasubstituted dihydropyridine carrying methoxycarbonyl, 2-(trifluoromethyl)phenyl and nitro substituents at positions 3, 4 and 5 respectively as well as two methyl substituents at positions 2 and 6.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Moltzau, LR1
Aronsen, JM1
Meier, S1
Nguyen, CH1
Hougen, K1
Ørstavik, Ø1
Sjaastad, I1
Christensen, G1
Skomedal, T1
Osnes, JB1
Levy, FO1
Qvigstad, E1
Aggarwal, R1
Boyden, PA1

Other Studies

2 other studies available for bay-k-8644 and Cardiovascular Stroke

ArticleYear
SERCA2 activity is involved in the CNP-mediated functional responses in failing rat myocardium.
    British journal of pharmacology, 2013, Volume: 170, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2013
Altered pharmacologic responsiveness of reduced L-type calcium currents in myocytes surviving in the infarcted heart.
    Journal of cardiovascular electrophysiology, 1996, Volume: 7, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1996