Page last updated: 2024-10-23

bay-k-8644 and Cardiovascular Diseases

bay-k-8644 has been researched along with Cardiovascular Diseases in 2 studies

3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester: A dihydropyridine derivative, which, in contrast to NIFEDIPINE, functions as a calcium channel agonist. The compound facilitates Ca2+ influx through partially activated voltage-dependent Ca2+ channels, thereby causing vasoconstrictor and positive inotropic effects. It is used primarily as a research tool.
Bay-K-8644 : A racemate comprising equimolar amounts of (R)- and (S)-Bay-K-8644
methyl 2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3-carboxylate : A pentasubstituted dihydropyridine carrying methoxycarbonyl, 2-(trifluoromethyl)phenyl and nitro substituents at positions 3, 4 and 5 respectively as well as two methyl substituents at positions 2 and 6.

Cardiovascular Diseases: Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Menhaji-Klotz, E1
Price, DA1
Lin, YK1
Chen, YJ1
Li, JY1
Chen, YL1
He, D1
Zuo, R1
Xiao, MJ1
Xu, DP1
Zheng, CY1
Wang, W1
He, RR1
Chen, Y1

Reviews

1 review available for bay-k-8644 and Cardiovascular Diseases

ArticleYear
Small molecules that promote regenerative repair for pancreatic and cardiovascular health.
    Bioorganic & medicinal chemistry letters, 2015, Dec-01, Volume: 25, Issue:23

    Topics: Cardiovascular Diseases; Cardiovascular System; Diabetes Mellitus; Drug Delivery Systems; Humans; Me

2015

Other Studies

1 other study available for bay-k-8644 and Cardiovascular Diseases

ArticleYear
Salvianolic acid A from Danhong Injection induces vasorelaxation by Regulating L-type calcium channel in isolated mouse arteries.
    Journal of ethnopharmacology, 2022, Oct-05, Volume: 296

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2022