bay-k-8644 has been researched along with Anoxemia in 16 studies
3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester: A dihydropyridine derivative, which, in contrast to NIFEDIPINE, functions as a calcium channel agonist. The compound facilitates Ca2+ influx through partially activated voltage-dependent Ca2+ channels, thereby causing vasoconstrictor and positive inotropic effects. It is used primarily as a research tool.
Bay-K-8644 : A racemate comprising equimolar amounts of (R)- and (S)-Bay-K-8644
methyl 2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3-carboxylate : A pentasubstituted dihydropyridine carrying methoxycarbonyl, 2-(trifluoromethyl)phenyl and nitro substituents at positions 3, 4 and 5 respectively as well as two methyl substituents at positions 2 and 6.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (12.50) | 18.7374 |
| 1990's | 7 (43.75) | 18.2507 |
| 2000's | 4 (25.00) | 29.6817 |
| 2010's | 3 (18.75) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wan, J | 1 |
| Yamamura, A | 1 |
| Zimnicka, AM | 1 |
| Voiriot, G | 1 |
| Smith, KA | 1 |
| Tang, H | 1 |
| Ayon, RJ | 1 |
| Choudhury, MS | 1 |
| Ko, EA | 1 |
| Wang, J | 1 |
| Wang, C | 1 |
| Makino, A | 1 |
| Yuan, JX | 1 |
| Xu, P | 1 |
| Cao, XB | 1 |
| Gao, L | 1 |
| Ma, HJ | 1 |
| Zhang, Y | 1 |
| Hefter, D | 1 |
| Kaiser, M | 1 |
| Weyer, SW | 1 |
| Papageorgiou, IE | 1 |
| Both, M | 1 |
| Kann, O | 1 |
| Müller, UC | 1 |
| Draguhn, A | 1 |
| Badejo, AM | 1 |
| Dhaliwal, JS | 1 |
| Casey, DB | 1 |
| Gallen, TB | 1 |
| Greco, AJ | 1 |
| Kadowitz, PJ | 1 |
| Jiang, RG | 1 |
| Eyzaguirre, C | 1 |
| Cornfield, DN | 1 |
| Stevens, T | 1 |
| McMurtry, IF | 1 |
| Abman, SH | 1 |
| Rodman, DM | 1 |
| Vannier, C | 1 |
| Croxton, TL | 1 |
| Farley, LS | 1 |
| Hirshman, CA | 1 |
| Bannister, NJ | 1 |
| Publicover, SJ | 1 |
| Carpenter, E | 1 |
| Wyatt, CN | 1 |
| Hatton, CJ | 1 |
| Bee, D | 1 |
| Peers, C | 2 |
| Armstead, WM | 1 |
| Malvin, GM | 1 |
| Walker, BR | 1 |
| Russell, MJ | 1 |
| Pelaez, NJ | 1 |
| Packer, CS | 1 |
| Forster, ME | 1 |
| Olson, KR | 1 |
| Shirahata, M | 1 |
| Fitzgerald, RS | 1 |
| Tolins, M | 1 |
| Weir, EK | 2 |
| Chesler, E | 1 |
| Nelson, DP | 1 |
| From, AH | 1 |
| Archer, SL | 1 |
| Tolins, JP | 1 |
| Raij, L | 1 |
16 other studies available for bay-k-8644 and Anoxemia
| Article | Year |
|---|---|
Chronic hypoxia selectively enhances L- and T-type voltage-dependent Ca2+ channel activity in pulmonary artery by upregulating Cav1.2 and Cav3.2.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3-Pyridinecarboxylic acid, 1,4-d | 2013 |
Inhibition of carotid sinus baroreflex in neonatal rats exposed to chronic intermittent hypobaric hypoxia.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2014 |
Amyloid Precursor Protein Protects Neuronal Network Function after Hypoxia via Control of Voltage-Gated Calcium Channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2016 |
Analysis of pulmonary vasodilator responses to the Rho-kinase inhibitor fasudil in the anesthetized rat.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13 | 2008 |
Calcium channels of cultured rat glomus cells in normoxia and acute hypoxia.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2005 |
Acute hypoxia causes membrane depolarization and calcium influx in fetal pulmonary artery smooth muscle cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1994 |
Inhibition of dihydropyridine-sensitive calcium entry in hypoxic relaxation of airway smooth muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1995 |
Interacting effects of Ca2+ and hypoxia in the induction of sarcolemmal damage in mouse diaphragm in vitro.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1995 |
Ca2+ channel currents in type I carotid body cells from normoxic and chronically hypoxic rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1996 |
Role of activation of calcium-sensitive K+ channels in NO- and hypoxia-induced pial artery vasodilation.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1997 |
Sites and ionic mechanisms of hypoxic vasoconstriction in frog skin.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3-Pyridinecarboxylic acid, 1,4-d | 2001 |
Intracellular and extracellular calcium utilization during hypoxic vasoconstriction of cyclostome aortas.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2001 |
Hypoxic suppression of K+ currents in type I carotid body cells: selective effect on the Ca2(+)-activated K+ current.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1990 |
Dependency of hypoxic chemotransduction in cat carotid body on voltage-gated calcium channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1991 |
Pulmonary vascular tone is increased by a voltage-dependent calcium channel potentiator.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1986 |
Hypoxic pulmonary vasoconstriction is enhanced by inhibition of the synthesis of an endothelium derived relaxing factor.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1989 |