bay-k-8644 has been researched along with Absence Seizure Disorder in 3 studies
3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester: A dihydropyridine derivative, which, in contrast to NIFEDIPINE, functions as a calcium channel agonist. The compound facilitates Ca2+ influx through partially activated voltage-dependent Ca2+ channels, thereby causing vasoconstrictor and positive inotropic effects. It is used primarily as a research tool.
Bay-K-8644 : A racemate comprising equimolar amounts of (R)- and (S)-Bay-K-8644
methyl 2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3-carboxylate : A pentasubstituted dihydropyridine carrying methoxycarbonyl, 2-(trifluoromethyl)phenyl and nitro substituents at positions 3, 4 and 5 respectively as well as two methyl substituents at positions 2 and 6.
| Excerpt | Relevance | Reference |
|---|---|---|
| "ethosuximide, an increase after i." | 1.31 | Opposite effects of T- and L-type Ca(2+) channels blockers in generalized absence epilepsy. ( Elants, C; Scheenen, W; van Luijtelaar, G; Wiaderna, D, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Durmus, N | 1 |
| Kaya, T | 1 |
| Gültürk, S | 1 |
| Demir, T | 1 |
| Parlak, M | 1 |
| Altun, A | 1 |
| van Luijtelaar, EL | 1 |
| Ates, N | 1 |
| Coenen, AM | 1 |
| van Luijtelaar, G | 1 |
| Wiaderna, D | 1 |
| Elants, C | 1 |
| Scheenen, W | 1 |
3 other studies available for bay-k-8644 and Absence Seizure Disorder
| Article | Year |
|---|---|
The effects of L type calcium channels on the electroencephalogram recordings in WAG/RIJ rat model of absence epilepsy.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2013 |
Role of L-type calcium channel modulation in nonconvulsive epilepsy in rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1995 |
Opposite effects of T- and L-type Ca(2+) channels blockers in generalized absence epilepsy.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2000 |