bay h 4502 has been researched along with Cancer of Prostate in 2 studies
bifonazole : A racemate comprising equimolar amounts of R- and S-bifonazole. It is a broad spectrum antifungal drug used for the treatment of fungal skin and nail infections.
1-[biphenyl-4-yl(phenyl)methyl]imidazole : A member of the class of imidazoles carrying an alpha-(biphenyl-4-yl)benzyl substituent at position 1.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Together, in PC3 human prostate cancer cells, bifonazole induced [Ca(2+)]i rises by inducing phospholipase C- and protein kinase C-dependent Ca(2+) release from the endoplasmic reticulum and Ca(2+) influx via non-store-operated pathways." | 1.40 | The mechanism of bifonazole-induced [Ca(2+)]i rises and non-Ca(2+)-triggered cell death in PC3 human prostate cancer cells. ( Cheng, JS; Chou, CT; Jan, CR; Kuo, CC; Kuo, DH; Liang, WZ; Shieh, P, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Clement, OO | 1 |
| Freeman, CM | 1 |
| Hartmann, RW | 1 |
| Handratta, VD | 1 |
| Vasaitis, TS | 1 |
| Brodie, AM | 1 |
| Njar, VC | 1 |
| Cheng, JS | 1 |
| Chou, CT | 1 |
| Liang, WZ | 1 |
| Kuo, CC | 1 |
| Shieh, P | 1 |
| Kuo, DH | 1 |
| Jan, CR | 1 |
2 other studies available for bay h 4502 and Cancer of Prostate
| Article | Year |
|---|---|
Three dimensional pharmacophore modeling of human CYP17 inhibitors. Potential agents for prostate cancer therapy.
Topics: Algorithms; Antineoplastic Agents; Azoles; Binding Sites; Enzyme Inhibitors; Humans; Hydrogen Bondin | 2003 |
The mechanism of bifonazole-induced [Ca(2+)]i rises and non-Ca(2+)-triggered cell death in PC3 human prostate cancer cells.
Topics: Apoptosis; Calcium; Calcium Signaling; Cell Line, Tumor; Dose-Response Relationship, Drug; Humans; I | 2014 |