bay-63-2521 and Idiopathic-Pulmonary-Fibrosis

bay-63-2521 has been researched along with Idiopathic-Pulmonary-Fibrosis* in 4 studies

Reviews

1 review(s) available for bay-63-2521 and Idiopathic-Pulmonary-Fibrosis

ArticleYear
Hypoxic Pulmonary Vasoconstriction and the Diffusing Capacity in Pulmonary Hypertension Secondary to Idiopathic Pulmonary Fibrosis.
    Journal of the American Heart Association, 2019, 08-20, Volume: 8, Issue:16

    Topics: Bosentan; Disease Progression; Endothelin Receptor Antagonists; Enzyme Activators; Humans; Hypertension, Pulmonary; Hypoxia; Idiopathic Pulmonary Fibrosis; Phosphodiesterase 5 Inhibitors; Pulmonary Arterial Hypertension; Pulmonary Circulation; Pulmonary Diffusing Capacity; Pulmonary Ventilation; Pyrazoles; Pyrimidines; Sildenafil Citrate; Treatment Failure; Vascular Remodeling; Vasoconstriction

2019

Other Studies

3 other study(ies) available for bay-63-2521 and Idiopathic-Pulmonary-Fibrosis

ArticleYear
Chronic lung disease-associated PH: PAH-approved drugs and established universal healthcare insurance in Japan.
    Respiratory investigation, 2020, Volume: 58, Issue:4

    Topics: Bosentan; Humans; Hypertension, Pulmonary; Idiopathic Pulmonary Fibrosis; Insurance Coverage; Japan; Phenylpropionates; Prevalence; Prognosis; Pulmonary Disease, Chronic Obstructive; Pyrazoles; Pyridazines; Pyrimidines; Sildenafil Citrate; Sulfonamides; Treatment Outcome; Universal Health Insurance

2020
Pulmonary hypertension associated with idiopathic interstitial pneumonia: is effective pharmacotherapy an impossible dream?
    The Lancet. Respiratory medicine, 2019, Volume: 7, Issue:9

    Topics: Humans; Hypertension, Pulmonary; Idiopathic Interstitial Pneumonias; Idiopathic Pulmonary Fibrosis; Pyrazoles; Pyrimidines

2019
Idiopathic interstitial pneumonia-associated pulmonary hypertension: A target for therapy?
    Respiratory medicine, 2017, Volume: 122 Suppl 1

    Advances in the treatment of idiopathic interstitial pneumonia (IIP) represent an urgent, unmet medical need for patients with this category of diffuse parenchymal lung disease. IIPs involve varying combinations of fibrosis and inflammation of unknown cause and may be associated with pulmonary hypertension (PH). When it occurs, PH is associated with higher oxygen needs, greater functional impairment, and increased mortality. However, whether or when PH is a maladaptive versus adaptive phenomenon remains to be determined. Despite their differing prognoses, it does appear that the IIPs may follow a similar course once PH supervenes. Therefore, it may be worthwhile to explore studies of PH medications in IIP as a group rather than as individual entities. Such a broad approach eliminates the need to nuance specific diagnoses and thereby facilitates study recruitment and broadens the applicability of the results.

    Topics: Cell Proliferation; Clinical Trials as Topic; Enzyme Activators; Extracellular Matrix; Fibroblasts; Humans; Hypertension, Pulmonary; Idiopathic Interstitial Pneumonias; Idiopathic Pulmonary Fibrosis; Lung Diseases, Interstitial; Nitric Oxide; Prognosis; Pyrazoles; Pyrimidines; United States

2017