bay-11-7085 and HIV-Infections

bay-11-7085 has been researched along with HIV-Infections* in 1 studies

Other Studies

1 other study(ies) available for bay-11-7085 and HIV-Infections

Article	Year
Inhibition of HIV-1 replication by a tricyclic coumarin GUT-70 in acutely and chronically infected cells. Bioorganic & medicinal chemistry letters, 2013, Feb-01, Volume: 23, Issue:3 The anti-HIV-1 activity of GUT-70, a natural product derived from the stem bark of Chlophyllum brasiliense, was evaluated. GUT-70 inhibited HIV-1 replication in both acutely and chronically infected cells through suppression of NF-κB. Our results strengthen the idea that NF-κB pathway is one of the potential targets to control HIV-1 replication and that GUT-70 could serve as a lead compound to develop novel therapeutic agents against HIV-1 infection. Topics: Antiviral Agents; Cell Line; Coumarins; HIV Infections; HIV-1; Humans; Inhibitory Concentration 50; Molecular Structure; NF-kappaB-Inducing Kinase; Protein Serine-Threonine Kinases; Virus Replication	2013

Article

Year

Inhibition of HIV-1 replication by a tricyclic coumarin GUT-70 in acutely and chronically infected cells.

Bioorganic & medicinal chemistry letters, 2013, Feb-01, Volume: 23, Issue:3

The anti-HIV-1 activity of GUT-70, a natural product derived from the stem bark of Chlophyllum brasiliense, was evaluated. GUT-70 inhibited HIV-1 replication in both acutely and chronically infected cells through suppression of NF-κB. Our results strengthen the idea that NF-κB pathway is one of the potential targets to control HIV-1 replication and that GUT-70 could serve as a lead compound to develop novel therapeutic agents against HIV-1 infection.

Topics: Antiviral Agents; Cell Line; Coumarins; HIV Infections; HIV-1; Humans; Inhibitory Concentration 50; Molecular Structure; NF-kappaB-Inducing Kinase; Protein Serine-Threonine Kinases; Virus Replication

2013