barbital has been researched along with Hyperplasia in 4 studies
5,5-diethylbarbituric acid : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by two ethyl groups. Formerly used as a hypnotic (sleeping aid).
Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The renal tumor promoting activity of barbital sodium (BBNa) and the role of renal tubular cell hyperplasia in tumor promotion following initiation with streptozotocin (STZ) was investigated." | 7.68 | Amelioration of sodium barbital-induced nephropathy and regenerative tubular hyperplasia after a single injection of streptozotocin does not abolish the renal tumor promoting effect of barbital sodium in male F344/NC4 rats. ( Diwan, BA; Konishi, N; Ward, JM, 1990) |
| "The renal tumor promoting activity of barbital sodium (BBNa) and the role of renal tubular cell hyperplasia in tumor promotion following initiation with streptozotocin (STZ) was investigated." | 3.68 | Amelioration of sodium barbital-induced nephropathy and regenerative tubular hyperplasia after a single injection of streptozotocin does not abolish the renal tumor promoting effect of barbital sodium in male F344/NC4 rats. ( Diwan, BA; Konishi, N; Ward, JM, 1990) |
| " Rats were dosed with sodium barbital in the feed at 0, 50, 250, 500, 1000, 2000 or 4000 p." | 1.31 | Promotion by sodium barbital induces early development but does not increase the multiplicity of hereditary renal tumors in Eker rats. ( David, CS; Donner, EM; Everitt, JI; Goldsworthy, TL; Harden, R; Janszen, DB; Wolf, DC, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Waalkes, MP | 1 |
| Diwan, BA | 3 |
| Ward, JM | 3 |
| Devor, DE | 1 |
| Goyer, RA | 1 |
| Kurata, Y | 1 |
| Uno, H | 1 |
| Rice, JM | 1 |
| Wolf, DC | 1 |
| Goldsworthy, TL | 1 |
| Janszen, DB | 1 |
| Harden, R | 1 |
| Donner, EM | 1 |
| David, CS | 1 |
| Everitt, JI | 1 |
| Konishi, N | 1 |
4 other studies available for barbital and Hyperplasia