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barbital and Cancer of Liver

barbital has been researched along with Cancer of Liver in 8 studies

5,5-diethylbarbituric acid : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by two ethyl groups. Formerly used as a hypnotic (sleeping aid).

Research Excerpts

ExcerptRelevanceReference
"In PB- and BS-treated livers, hepatomegaly was attributable to hepatocyte proliferation and enzyme induction."1.31Apoptosis and cell proliferation in rat hepatocytes induced by barbiturates. ( Fujieda, Y; Furukawa, S; Goryo, M; Hayashi, K; Ikeyama, S; Miyamoto, Y; Okada, K; Tamura, T; Usuda, K, 2000)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19904 (50.00)18.7374
1990's3 (37.50)18.2507
2000's1 (12.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Furukawa, F1
Toyoda, K1
Kokubo, T1
Takahashi, M1
Hayashi, Y1
Diwan, BA5
Anderson, LM2
Ward, JM3
Henneman, JR2
Rice, JM5
Riggs, CW1
Logsdon, D1
Haines, DC1
Olivero, OA1
Yuspa, SH1
Poirier, MC1
Furukawa, S1
Usuda, K1
Fujieda, Y1
Tamura, T1
Miyamoto, Y1
Hayashi, K1
Ikeyama, S1
Goryo, M1
Okada, K1
Waalkes, MP1
Weghorst, CM1
Bare, RM1
Ohshima, M1
Nims, RW2
Hu, H1
Lubet, RA2
Devor, DE1

Other Studies

8 other studies available for barbital and Cancer of Liver

ArticleYear
[Establishment of test methods for examining promoters of hepatocarcinogenesis--promoting effects of phenobarbital, butylated hydroxytoluene and barbital].
    Eisei Shikenjo hokoku. Bulletin of National Institute of Hygienic Sciences, 1984, Issue:102

    Topics: Animals; Barbital; Barbiturates; Butylated Hydroxytoluene; Cocarcinogenesis; Diethylnitrosamine; Liv

1984
Transplacental carcinogenesis by cisplatin in F344/NCr rats: promotion of kidney tumors by postnatal administration of sodium barbital.
    Toxicology and applied pharmacology, 1995, Volume: 132, Issue:1

    Topics: Animals; Barbital; Body Weight; Carcinogenicity Tests; Carcinogens; Cisplatin; Drug Synergism; Femal

1995
Multiorgan transplacental and neonatal carcinogenicity of 3'-azido-3'-deoxythymidine in mice.
    Toxicology and applied pharmacology, 1999, Nov-15, Volume: 161, Issue:1

    Topics: Animals; Animals, Newborn; Anti-HIV Agents; Barbital; Body Weight; Carcinogens; Dose-Response Relati

1999
Apoptosis and cell proliferation in rat hepatocytes induced by barbiturates.
    The Journal of veterinary medical science, 2000, Volume: 62, Issue:1

    Topics: Animals; Apoptosis; Barbital; Barbiturates; Body Weight; Bromodeoxyuridine; Cell Division; Hepatomeg

2000
Anticarcinogenic effects of cadmium in B6C3F1 mouse liver and lung.
    Toxicology and applied pharmacology, 1991, Sep-01, Volume: 110, Issue:2

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Barbital; Cadmium; Cadmium Chloride; Diethylni

1991
Promotion by sodium barbital of renal cortical and transitional cell tumors, but not intestinal tumors, in F344 rats given methyl(acetoxymethyl)nitrosamine, and lack of effect of phenobarbital, amobarbital, or barbituric acid on development of either rena
    Carcinogenesis, 1989, Volume: 10, Issue:1

    Topics: Adenoma; Amobarbital; Animals; Barbital; Barbiturates; Carcinogens; Carcinoma; Carcinoma, Renal Cell

1989
Tumor promoting activities of ethylphenylacetylurea and diethylacetylurea, the ring hydrolysis products of barbiturate tumor promoters phenobarbital and barbital, in rat liver and kidney initiated by N-nitrosodiethylamine.
    Carcinogenesis, 1989, Volume: 10, Issue:1

    Topics: Animals; Barbital; Body Weight; Carcinogens; Cytochrome P-450 Enzyme System; Diethylnitrosamine; Enz

1989
Induction of alkoxyresorufin O-dealkylases, epoxide hydrolase, and liver weight gain: correlation with liver tumor-promoting potential in a series of barbiturates.
    Carcinogenesis, 1987, Volume: 8, Issue:1

    Topics: 7-Alkoxycoumarin O-Dealkylase; Amobarbital; Animals; Barbital; Barbiturates; Cytochrome P-450 CYP2B1

1987