barbital has been researched along with Cancer of Kidney in 13 studies
5,5-diethylbarbituric acid : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by two ethyl groups. Formerly used as a hypnotic (sleeping aid).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The renal tumor promoting activity of barbital sodium (BBNa) and the role of renal tubular cell hyperplasia in tumor promotion following initiation with streptozotocin (STZ) was investigated." | 7.68 | Amelioration of sodium barbital-induced nephropathy and regenerative tubular hyperplasia after a single injection of streptozotocin does not abolish the renal tumor promoting effect of barbital sodium in male F344/NC4 rats. ( Diwan, BA; Konishi, N; Ward, JM, 1990) |
| "The renal tumor promoting activity of barbital sodium (BBNa) and the role of renal tubular cell hyperplasia in tumor promotion following initiation with streptozotocin (STZ) was investigated." | 3.68 | Amelioration of sodium barbital-induced nephropathy and regenerative tubular hyperplasia after a single injection of streptozotocin does not abolish the renal tumor promoting effect of barbital sodium in male F344/NC4 rats. ( Diwan, BA; Konishi, N; Ward, JM, 1990) |
| " Furthermore, initiation-promotion experiments demonstrated a strong correlation between the dose-response of cell proliferation and the incidence of preneoplastic and neoplastic lesions." | 2.38 | Cell proliferation and renal carcinogenesis. ( Short, BG, 1993) |
| " Rats were dosed with sodium barbital in the feed at 0, 50, 250, 500, 1000, 2000 or 4000 p." | 1.31 | Promotion by sodium barbital induces early development but does not increase the multiplicity of hereditary renal tumors in Eker rats. ( David, CS; Donner, EM; Everitt, JI; Goldsworthy, TL; Harden, R; Janszen, DB; Wolf, DC, 2000) |
| " In contrast, only DEHP and BBS induced toxic renal lesions." | 1.27 | The chronic hepatic or renal toxicity of di(2-ethylhexyl) phthalate, acetaminophen, sodium barbital, and phenobarbital in male B6C3F1 mice: autoradiographic, immunohistochemical, and biochemical evidence for levels of DNA synthesis not associated with car ( Anderson, LM; Diwan, BA; Hagiwara, A; Lindsey, K; Ward, JM, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (30.77) | 18.7374 |
| 1990's | 7 (53.85) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mantle, PG | 1 |
| Dobrota, M | 1 |
| Gillett, CE | 1 |
| Odell, EW | 1 |
| Pinder, SE | 1 |
| Short, BG | 1 |
| Waalkes, MP | 1 |
| Diwan, BA | 9 |
| Ward, JM | 9 |
| Devor, DE | 1 |
| Goyer, RA | 1 |
| Anderson, LM | 2 |
| Henneman, JR | 1 |
| Rice, JM | 4 |
| Kurata, Y | 2 |
| Uno, H | 1 |
| Wolf, DC | 1 |
| Goldsworthy, TL | 1 |
| Janszen, DB | 1 |
| Harden, R | 1 |
| Donner, EM | 1 |
| David, CS | 1 |
| Everitt, JI | 1 |
| Konishi, N | 2 |
| Donovan, PJ | 1 |
| Hagiwara, A | 2 |
| Ohshima, M | 1 |
| Nims, RW | 1 |
| Hu, H | 1 |
| Lubet, RA | 1 |
| Lindsey, K | 1 |
1 review available for barbital and Cancer of Kidney
| Article | Year |
|---|---|
Cell proliferation and renal carcinogenesis.
Topics: Alpha-Globulins; Animals; Barbital; Cell Division; Dimethylnitrosamine; DNA Damage; Female; Humans; | 1993 |
12 other studies available for barbital and Cancer of Kidney