barbital has been researched along with Body Weight in 30 studies
5,5-diethylbarbituric acid : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by two ethyl groups. Formerly used as a hypnotic (sleeping aid).
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The renal tumor promoting activity of barbital sodium (BBNa) and the role of renal tubular cell hyperplasia in tumor promotion following initiation with streptozotocin (STZ) was investigated." | 7.68 | Amelioration of sodium barbital-induced nephropathy and regenerative tubular hyperplasia after a single injection of streptozotocin does not abolish the renal tumor promoting effect of barbital sodium in male F344/NC4 rats. ( Diwan, BA; Konishi, N; Ward, JM, 1990) |
| "To observe the dispositional and functional tolerance to and physical dependence on barbital, the influence of repeated administration of the drug on serum barbital levels, coordinative motion, body weight, and cortical evoked potential was assessed." | 3.68 | Observation of the development of tolerance to and physical dependence on barbital by cortical evoked potential in rats. ( Shimada, A; Yanagita, T, 1991) |
| "The renal tumor promoting activity of barbital sodium (BBNa) and the role of renal tubular cell hyperplasia in tumor promotion following initiation with streptozotocin (STZ) was investigated." | 3.68 | Amelioration of sodium barbital-induced nephropathy and regenerative tubular hyperplasia after a single injection of streptozotocin does not abolish the renal tumor promoting effect of barbital sodium in male F344/NC4 rats. ( Diwan, BA; Konishi, N; Ward, JM, 1990) |
| "Following withdrawal from chronic barbital administration, 6-hydroxydopamine pretreated rats show a greater number and an earlier onset of spontaneous convulsive seizures than do rats pretreated with the saline-ascorbic acid vehicle." | 3.65 | Effect of 6-hydroxydopamine pretreatment on spontaneous convulsions induced by barbital withdrawal. ( Morgan, WW, 1976) |
| "In PB- and BS-treated livers, hepatomegaly was attributable to hepatocyte proliferation and enzyme induction." | 1.31 | Apoptosis and cell proliferation in rat hepatocytes induced by barbiturates. ( Fujieda, Y; Furukawa, S; Goryo, M; Hayashi, K; Ikeyama, S; Miyamoto, Y; Okada, K; Tamura, T; Usuda, K, 2000) |
| "After stopping the treatment, the body weight and food consumption in the diazepam 100 and 300 mg/kg groups tended to decrease or decreased to values lower than those in the control group, whereas these parameters in the S-(+)-DN-2327 30, 100 and 300 mg/kg groups were comparable to the control group values." | 1.29 | A nonbenzodiazepine partial agonist, S-(+)-DN-2327, has minimal physical dependence-producing liability, but shows cross-dependence on barbital in rats. ( Awasaki, Y; Inui, Y; Nishida, N; Yamamoto, M, 1996) |
| " The "low" level chronic dosing merely prolonged the time required to develop physical dependence of severity comparable to that produced by shorter durations of "high" level chronic dosing." | 1.27 | Physical dependence produced by long duration, low dose chronic barbital treatment. ( Hinman, DJ; Okamoto, M, 1984) |
| " During chronic administration of brotizolam, triazolam and diazepam all animals gained body weight." | 1.27 | Physical dependence capacity of brotizolam in rhesus monkeys. 2nd communication: primary dependence and barbital substitution. ( Stockhaus, K, 1986) |
| "Mequitazine is a new phenothiazine derivative with potent antihistaminic activity developed by Pharmuka, Co." | 1.26 | [Studies on the barbital-type physical dependence liability of mequitazine in mice and rats (author's transl)]. ( Kaneto, H, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (70.00) | 18.7374 |
| 1990's | 8 (26.67) | 18.2507 |
| 2000's | 1 (3.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| LAL, H | 1 |
| BLAIR, W | 1 |
| EHRLICH, R | 1 |
| SHEFNER, A | 1 |
| Kaneto, H | 2 |
| Tagashira, E | 1 |
| Hiramori, T | 1 |
| Urano, T | 1 |
| Yanaura, S | 2 |
| Jänicke, UA | 1 |
| Coper, H | 1 |
| Okamoto, M | 1 |
| Hinman, DJ | 1 |
| Kosaka, N | 1 |
| Takasu, M | 1 |
| Mino, T | 1 |
| Hiasa, Y | 1 |
| Kitahori, Y | 1 |
| Ohshima, M | 2 |
| Fujita, T | 1 |
| Yuasa, T | 1 |
| Konishi, N | 2 |
| Miyashiro, A | 1 |
| Flint, BA | 1 |
| Ho, IK | 1 |
| Mori, H | 1 |
| Tanaka, T | 1 |
| Nishikawa, A | 1 |
| Takahashi, M | 1 |
| Williams, GM | 1 |
| Diwan, BA | 7 |
| Anderson, LM | 2 |
| Ward, JM | 6 |
| Henneman, JR | 1 |
| Rice, JM | 5 |
| Suzuki, T | 2 |
| Mizoguchi, H | 1 |
| Motegi, H | 1 |
| Awano, H | 1 |
| Misawa, M | 1 |
| Inui, Y | 1 |
| Yamamoto, M | 1 |
| Awasaki, Y | 1 |
| Nishida, N | 1 |
| Riggs, CW | 1 |
| Logsdon, D | 1 |
| Haines, DC | 1 |
| Olivero, OA | 1 |
| Yuspa, SH | 1 |
| Poirier, MC | 1 |
| Furukawa, S | 1 |
| Usuda, K | 1 |
| Fujieda, Y | 1 |
| Tamura, T | 1 |
| Miyamoto, Y | 1 |
| Hayashi, K | 1 |
| Ikeyama, S | 1 |
| Goryo, M | 1 |
| Okada, K | 1 |
| Miyasato, K | 1 |
| Morgan, WW | 3 |
| Huffman, RD | 1 |
| Pfeil, KA | 2 |
| Gonzales, EG | 2 |
| Harris, RA | 1 |
| Case, J | 1 |
| Csáky, TZ | 1 |
| Varga, F | 1 |
| Zimmerberg, B | 1 |
| Brett, MB | 1 |
| Kurata, Y | 1 |
| Shimada, A | 1 |
| Yanagita, T | 1 |
| Nims, RW | 2 |
| Hu, H | 2 |
| Lubet, RA | 2 |
| Stockhaus, K | 1 |
| Koike, Y | 1 |
| Yoshii, T | 1 |
| Dove, LF | 1 |
| Khanna, JM | 1 |
| Lê, AD | 1 |
| Kalant, H | 1 |
| Kim, C | 1 |
30 other studies available for barbital and Body Weight
| Article | Year |
|---|---|
EFFECTS OF STAPHYLOCOCCAL ENTEROTOXIN ON BARBITAL TOXICITY.
Topics: Antitoxins; Barbital; Barbiturates; Body Weight; Enterotoxins; Mice; Pharmacology; Research; Staphyl | 1964 |
[Studies on the barbital-type physical dependence liability of mequitazine in mice and rats (author's transl)].
Topics: Animals; Barbital; Body Weight; Central Nervous System Depressants; Chlorpromazine; Diazepam; Histam | 1981 |
Formation of physical dependence on barbiturates and cerebral monoamines.
Topics: alpha-Methyltyrosine; Animals; Barbital; Barbiturates; Biogenic Amines; Body Weight; Brain; Catechol | 1983 |
Repeated withdrawal from barbital as a drive for 'drug taking behavior' in rats.
Topics: Animals; Barbital; Barbiturates; Behavior, Animal; Body Temperature; Body Weight; Drinking; Drug Tol | 1984 |
Physical dependence produced by long duration, low dose chronic barbital treatment.
Topics: Animals; Barbital; Barbiturates; Body Weight; Cats; Central Nervous System; Female; Humans; Male; Mo | 1984 |
[Studies on the physical dependence liability to guanabenz].
Topics: Analgesics; Animals; Antihypertensive Agents; Barbital; Body Weight; Drug Synergism; Guanabenz; Guan | 1982 |
Promoting effects of phenobarbital and barbital on development of thyroid tumors in rats treated with N-bis(2-hydroxypropyl)nitrosamine.
Topics: Animals; Barbital; Barbiturates; Body Weight; Carcinogens; Kidney; Liver; Male; Neoplasms, Experimen | 1982 |
Continuous administration of barbital by pellet implantation.
Topics: Animals; Barbital; Barbiturates; Behavior, Animal; Body Temperature; Body Weight; Drug Implants; Dru | 1980 |
Enhancing effect of barbital on N-2-fluorenylacetamide-induced rat liver lesions.
Topics: 2-Acetylaminofluorene; Animals; Barbital; Barbiturates; Body Weight; Kinetics; Liver; Male; Organ Si | 1981 |
Transplacental carcinogenesis by cisplatin in F344/NCr rats: promotion of kidney tumors by postnatal administration of sodium barbital.
Topics: Animals; Barbital; Body Weight; Carcinogenicity Tests; Carcinogens; Cisplatin; Drug Synergism; Femal | 1995 |
Effects of nifedipine on physical dependence on barbital or diazepam in rats.
Topics: Analysis of Variance; Animals; Barbital; Body Weight; Calcium Channel Blockers; Calcium Channels; Di | 1995 |
A nonbenzodiazepine partial agonist, S-(+)-DN-2327, has minimal physical dependence-producing liability, but shows cross-dependence on barbital in rats.
Topics: Animals; Anti-Anxiety Agents; Area Under Curve; Barbital; Behavior, Animal; Binding, Competitive; Bo | 1996 |
Multiorgan transplacental and neonatal carcinogenicity of 3'-azido-3'-deoxythymidine in mice.
Topics: Animals; Animals, Newborn; Anti-HIV Agents; Barbital; Body Weight; Carcinogens; Dose-Response Relati | 1999 |
Apoptosis and cell proliferation in rat hepatocytes induced by barbiturates.
Topics: Animals; Apoptosis; Barbital; Barbiturates; Body Weight; Bromodeoxyuridine; Cell Division; Hepatomeg | 2000 |
[Experimental study on development of physical dependence on alcohol and cross physical dependence liability of diazepam and barbital to alcohol in rhesus monkeys (author's transl)].
Topics: Alcoholism; Animals; Barbital; Barbiturates; Body Weight; Diazepam; Female; Haplorhini; Humans; Maca | 1978 |
Effect of synthesis inhibition on the levels of brain catecholamines in barbital-dependent rats.
Topics: Animals; Barbital; Barbiturates; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Body Weight; | 1978 |
Effects of maternal consumption of ethanol, barbital, or chlordiazepoxide on the behavior of the offspring.
Topics: Alcohol Drinking; Animals; Animals, Newborn; Avoidance Learning; Barbital; Barbiturates; Behavior, A | 1979 |
Catecholamine concentration in discrete brain areas following the withdrawal of barbital dependent rats.
Topics: Animals; Barbital; Barbiturates; Body Weight; Brain; Brain Stem; Cerebral Cortex; Corpus Striatum; D | 1977 |
Effect of 6-hydroxydopamine pretreatment on spontaneous convulsions induced by barbital withdrawal.
Topics: Animals; Ascorbic Acid; Barbital; Barbiturates; Body Weight; Dopamine; Humans; Hydroxydopamines; Mal | 1976 |
Subepithelial capillary blood flow estimated from blood-to-lumen flux of barbital in ileum of rats.
Topics: Animals; Barbital; Barbiturates; Body Weight; Capillaries; Cardiac Output; Hypothermia, Induced; Ile | 1975 |
Effects of early environmental experience on self-administration of amphetamine and barbital.
Topics: Amphetamine; Animals; Barbital; Behavior, Animal; Body Weight; Environment; Female; Male; Rats; Self | 1992 |
Lack of renal tumour-initiating activity of a single dose of potassium bromate, a genotoxic renal carcinogen in male F344/NCr rats.
Topics: Animals; Barbital; Body Weight; Bromates; Carcinogens; Kidney Neoplasms; Male; Organ Size; Rats; Rat | 1992 |
Observation of the development of tolerance to and physical dependence on barbital by cortical evoked potential in rats.
Topics: Animals; Barbital; Body Weight; Drug Tolerance; Evoked Potentials, Auditory; Male; Motor Activity; R | 1991 |
Amelioration of sodium barbital-induced nephropathy and regenerative tubular hyperplasia after a single injection of streptozotocin does not abolish the renal tumor promoting effect of barbital sodium in male F344/NC4 rats.
Topics: Adenoma; Animals; Barbital; Body Weight; DNA; Hyperplasia; Kidney; Kidney Neoplasms; Liver; Male; Ne | 1990 |
Tumor promoting activities of ethylphenylacetylurea and diethylacetylurea, the ring hydrolysis products of barbiturate tumor promoters phenobarbital and barbital, in rat liver and kidney initiated by N-nitrosodiethylamine.
Topics: Animals; Barbital; Body Weight; Carcinogens; Cytochrome P-450 Enzyme System; Diethylnitrosamine; Enz | 1989 |
P-450 enzyme induction by 5-ethyl-5-phenylhydantoin and 5,5-diethylhydantoin, analogues of barbiturate tumor promoters phenobarbital and barbital, and promotion of liver and thyroid carcinogenesis initiated by N-nitrosodiethylamine in rats.
Topics: Animals; Barbital; Barbiturates; Body Weight; Cytochrome P-450 Enzyme System; Diethylnitrosamine; En | 1988 |
Physical dependence capacity of brotizolam in rhesus monkeys. 2nd communication: primary dependence and barbital substitution.
Topics: Animals; Azepines; Barbital; Barbiturates; Body Weight; Diazepam; Female; Hypnotics and Sedatives; M | 1986 |
[Sex differences in the physical dependence on barbital in rats].
Topics: Animals; Barbital; Barbiturates; Body Weight; Brain; Female; Male; Rats; Rats, Inbred Strains; Sex F | 1986 |
Comparative tumor-promoting activities of phenobarbital, amobarbital, barbital sodium, and barbituric acid on livers and other organs of male F344/NCr rats following initiation with N-nitrosodiethylamine.
Topics: Amobarbital; Animals; Barbital; Barbiturates; Body Weight; Diethylnitrosamine; Liver Neoplasms, Expe | 1985 |
Differential sensitivity to ethanol, pentobarbital, and barbital in spontaneously hypertensive and normotensive Wistar-Kyoto rats.
Topics: Animals; Barbital; Barbiturates; Body Weight; Ethanol; Female; Pentobarbital; Rats; Rats, Inbred SHR | 1985 |