barakol has been researched along with Disease-Models--Animal* in 1 studies
1 other study(ies) available for barakol and Disease-Models--Animal
Article | Year |
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Is barakol anxiolytic?
A recent report suggested that barakol, a biologically active extract of the south-east Asian plant, Cassia siamea, has anxiolytic properties. The purpose of the present study was to replicate and extend these findings by examining the dose-response effects of barakol (0-20 mg/kg) in two pharmacologically validated tests of rat anxiety: the elevated plus-maze and the shock-probe burying tests. Although the purity of our sample of barakol was confirmed by chemical analysis, we found no evidence of its anxiolytic effects in either the plus-maze or shock-probe burying tests. Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Benzopyrans; Disease Models, Animal; Electroshock; Escape Reaction; Exploratory Behavior; Male; Maze Learning; Motor Activity; Phenalenes; Rats; Rats, Sprague-Dawley; Single-Blind Method | 1998 |