barakol and Disease-Models--Animal

barakol has been researched along with Disease-Models--Animal* in 1 studies

Other Studies

1 other study(ies) available for barakol and Disease-Models--Animal

ArticleYear
Is barakol anxiolytic?
    Behavioural pharmacology, 1998, Volume: 9, Issue:4

    A recent report suggested that barakol, a biologically active extract of the south-east Asian plant, Cassia siamea, has anxiolytic properties. The purpose of the present study was to replicate and extend these findings by examining the dose-response effects of barakol (0-20 mg/kg) in two pharmacologically validated tests of rat anxiety: the elevated plus-maze and the shock-probe burying tests. Although the purity of our sample of barakol was confirmed by chemical analysis, we found no evidence of its anxiolytic effects in either the plus-maze or shock-probe burying tests.

    Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Benzopyrans; Disease Models, Animal; Electroshock; Escape Reaction; Exploratory Behavior; Male; Maze Learning; Motor Activity; Phenalenes; Rats; Rats, Sprague-Dawley; Single-Blind Method

1998