balafilcon-a and Myopia

To assess the effect of two silicone hydrogel contact lenses with high oxygen permeability in patients having photorefractive keratectomy (PRK).. Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.. Sixty patients (120 eyes) who had bilateral PRK were enrolled in this double blind clinical trial. Each patient was fitted with a Lotrafilcon B (Air Optix(®)AQUA, Ciba Vision, Duluth, GA, USA) lens in one eye and a Balafilcon A (PureVision™ Bausch & Lomb, Rochester, NY, USA) lens in the fellow eye. Patients' responses to a subjective questionnaire in terms of pain, foreign body sensation, photophobia, blurred vision and epiphora were evaluated on the first and third postoperative days.. Mean pain score for Lotrafilcon B and Balafilcon A contact lenses was 4.43±3.18 vs. 5.45±3.37 on the first postoperative day and 3.43±3.23 vs. 3.88±3.01 on the third postoperative day. However, the difference was only significant in the first 24h after surgery (P=0.032). Foreign body sensation was clinically higher with Balafilcon A contact lens (5.0±3.47 vs. 4.08±3.34 on day 1 and 4.98±3.52 vs. 3.55±3.20 on day 3) and the difference was statistically significant on the first and the third postoperative days (P=0.042 and 0.002, respectively). There was no statistically significant difference between two contact lenses in terms of photophobia, epiphora and blurred vision (P>0.05).. The Lotrafilcon B lens resulted in significantly less postoperative pain and discomfort after PRK, especially in the first 24h after PRK.

Topics: Adolescent; Adult; Bandages, Hydrocolloid; Contact Lenses, Hydrophilic; Double-Blind Method; Female; Follow-Up Studies; Humans; Hydrogels; Male; Middle Aged; Myopia; Pain, Postoperative; Photorefractive Keratectomy; Retrospective Studies; Silicones; Young Adult

To evaluate two different soft contact lens materials for continuous-wear bandage contact lenses after laser epithelial keratomileusis (LASEK).. A prospective, observer-masked study was conducted of 32 eyes of 16 consecutive patients. Inclusion criteria were candidates for bilateral LASEK, myopia of < or = -6.00 diopters (D), astigmatism < -1.50 D, and bilateral best spectacle-corrected visual acuity of 20/20 or better. Patients were randomly selected for a balafilcon A (PureVision; Bausch & Lomb) bandage contact lens in one eye and a poly-2-hydroxyethylmethacrylate-co-methacrylate glycerol (EquiS 60; mark'ennovy) in the fellow eye. Corneal epithelial status, conjunctival and limbal hyperemia, lens movement, contact lens debris, and the responses to a subjective comfort questionnaire were assessed postoperatively. The parameters were evaluated preoperatively and 1 and 5 days postoperatively. Paired Student t test and chi-square tests were used when appropriate.. Thirty-two eyes of 16 consecutive patients who underwent LASEK to correct low to moderate myopia were analyzed. The mean spherical equivalent refraction was -3.25 D. There was no difference in conjunctival or limbal hyperemia, contact lens debris, or subjective comfort between lenses at any postoperative visit. In contrast, the corneal epithelial status was statistically better in the eyes with a silicone bandage contact lens 5 days after LASEK (P = .01).. The results suggest that the bandage contact lens material used after LASEK affects the corneal epithelial healing process.

Topics: Adult; Astigmatism; Contact Lenses, Hydrophilic; Epithelium, Corneal; Follow-Up Studies; Humans; Hydrogels; Keratectomy, Subepithelial, Laser-Assisted; Methacrylates; Myopia; Occlusive Dressings; Polyhydroxyethyl Methacrylate; Prospective Studies; Refraction, Ocular; Silicones; Visual Acuity; Wound Healing