balafilcon-a and Corneal-Edema

To identify the corneal swelling response associated with silicone hydrogel contact lens wear.. Twenty-five subjects were recruited to participate in this single-center, controlled, single-masked, clinical trial. The corneal swelling response was evaluated by central corneal pachymetry after overnight wear of balafilcon A, etafilcon A, lotrafilcon A, senofilcon A, and no lens wear. More specifically, after 8 hours of closed-eye wear of each material, corneal thickness was measured immediately on eye opening, in addition to the first 4 hours of open-eye wear. Paired t tests were used to compare the swelling response from each condition to that associated with senofilcon A, and given the numerous statistical comparisons, a P value of

Topics: Circadian Rhythm; Contact Lenses, Hydrophilic; Corneal Edema; Cross-Over Studies; Humans; Hydrogels; Methacrylates; Oxygen; Permeability; Silicones; Single-Blind Method