bakuchiol and Breast-Neoplasms

bakuchiol has been researched along with Breast-Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for bakuchiol and Breast-Neoplasms

Article	Year
[Vitro antitumor activity and synthesis of the key intermediate of bakuchiol]. Yao xue xue bao = Acta pharmaceutica Sinica, 2010, Volume: 45, Issue:4 The in vitro antitumor activity of bakuchiol was exploited, compared with tamoxifen. The result of biological activities showed that bakuchiol could inhibit human breast cancer and the IC50 values were 2.89 x 10(-5) mol L(-1) and 8.29 x 10(-3) mol L(-1) against the cells line T-47D and MDA-MB-231 respectively. On the other hand, the key intermediate to synthesize bakuchiol was obtained by the method of Ireland-Claisen rearrangement. Comparing with traditional Claisen rearrangement, the reaction conditions are milder and the reaction reagents are safer. Topics: Antineoplastic Agents, Hormonal; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Humans; Inhibitory Concentration 50; Phenols; Plants, Medicinal; Psoralea; Tamoxifen	2010

Article

Year

[Vitro antitumor activity and synthesis of the key intermediate of bakuchiol].

Yao xue xue bao = Acta pharmaceutica Sinica, 2010, Volume: 45, Issue:4

The in vitro antitumor activity of bakuchiol was exploited, compared with tamoxifen. The result of biological activities showed that bakuchiol could inhibit human breast cancer and the IC50 values were 2.89 x 10(-5) mol L(-1) and 8.29 x 10(-3) mol L(-1) against the cells line T-47D and MDA-MB-231 respectively. On the other hand, the key intermediate to synthesize bakuchiol was obtained by the method of Ireland-Claisen rearrangement. Comparing with traditional Claisen rearrangement, the reaction conditions are milder and the reaction reagents are safer.

Topics: Antineoplastic Agents, Hormonal; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Humans; Inhibitory Concentration 50; Phenols; Plants, Medicinal; Psoralea; Tamoxifen

2010