Page last updated: 2024-08-24

baicalin and Fibrosis

baicalin has been researched along with Fibrosis in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (42.86)24.3611
2020's8 (57.14)2.80

Authors

AuthorsStudies
El-Kashef, DH; Zaghloul, AM; Zaghloul, RA1
Jiang, Q; Wang, H; Zhang, L1
Li, L; Liu, Q; Shi, L; Wang, L; Wang, X; Wu, W; Wu, Z; Zhou, X1
Hao, Y; Hu, H; Li, W; Liang, W; Peng, Z; Zou, Z1
Alcalde-Estévez, E; Castillo, C; Castro, A; Costa, IG; Fernández, L; Herrero, JI; Jansen, J; Kramann, R; Lamas, S; Miguel, V; Nagai, J; Ranz, I; Reimer, KC; Rey-Serra, C; Rodríguez González-Moro, JM; Sancho, D; Sevilla, L; Sirera, B; Tituaña, J1
Chen, G; Du, JW; Fan, XY; Feng, J; Jin, YL; Nie, Q; Zheng, XP1
Liang, R; Wang, P; Xu, L; Yang, C; Zhang, S1
He, SD; Huang, SG; Li, DY; Sun, CX; Tan, N; Zhu, HJ1
Cai, Y; Li, X; Liu, F; Ma, W; Qiu, J; Wu, B; Xiao, Y; Zhang, G1
Zhu, QJ1
Cai, Y; Huang, B; Huang, J; Liu, X; Wu, B; Xiao, Y; Ye, J; Zhang, G; Zhou, Y; Zhu, L1
Deng, Q; Lun, W; Wu, X; Zhang, W; Zhi, F1
Mao, HX; Tan, YJ; Zhu, CL1
Hu, C; Hu, M; Li, L; Lin, M; Rong, R; Sidikejiang, N; Wang, X; Zhang, C; Zheng, L1

Reviews

1 review(s) available for baicalin and Fibrosis

ArticleYear
[Research advances on baicalin and baicalein as potential therapeutic agents for fibrotic disease].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2017, Volume: 42, Issue:7

    Topics: Fibrosis; Flavanones; Flavonoids; Humans

2017

Other Studies

13 other study(ies) available for baicalin and Fibrosis

ArticleYear
Hepatoprotective effect of Baicalin against thioacetamide-induced cirrhosis in rats: Targeting NOX4/NF-κB/NLRP3 inflammasome signaling pathways.
    Life sciences, 2022, Apr-15, Volume: 295

    Topics: Animals; Antioxidants; Fibrosis; Flavonoids; Inflammasomes; Inflammation; Liver; Liver Cirrhosis; Male; NADPH Oxidase 4; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Thioacetamide

2022
Baicalin protects against renal interstitial fibrosis in mice by inhibiting the TGF-β/Smad signalling pathway.
    Pharmaceutical biology, 2022, Volume: 60, Issue:1

    Topics: Animals; Fibrosis; Flavonoids; Kidney; Kidney Diseases; Male; Mice; Mice, Inbred C57BL; Signal Transduction; Transforming Growth Factor beta; Transforming Growth Factor beta1; Ureteral Obstruction

2022
Baicalin prevents fibrosis of human trabecular meshwork cells via inhibiting the MyD88/NF-κB pathway.
    European journal of pharmacology, 2023, Jan-05, Volume: 938

    Topics: Blotting, Western; Cells, Cultured; Fibrosis; Glaucoma, Open-Angle; Humans; Myeloid Differentiation Factor 88; NF-kappa B; Toll-Like Receptor 4; Trabecular Meshwork; Transforming Growth Factor beta2

2023
Baicalin ameliorates renal fibrosis by upregulating CPT1α-mediated fatty acid oxidation in diabetic kidney disease.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2024, Volume: 122

    Topics: Animals; Diabetes Mellitus; Diabetic Nephropathies; Fatty Acids; Fibrosis; Humans; Kidney; Mice; RNA, Messenger

2024
Enhanced fatty acid oxidation through metformin and baicalin as therapy for COVID-19 and associated inflammatory states in lung and kidney.
    Redox biology, 2023, Volume: 68

    Topics: AMP-Activated Protein Kinases; Animals; COVID-19; Fatty Acids; Fibrosis; Humans; Inflammation; Kidney; Lung; Metformin; Respiratory Distress Syndrome; Transforming Growth Factor beta

2023
Kidney-targeted baicalin-lysozyme conjugate ameliorates renal fibrosis in rats with diabetic nephropathy induced by streptozotocin.
    BMC nephrology, 2020, 05-12, Volume: 21, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Drug Carriers; Drug Delivery Systems; Fibrosis; Flavonoids; Insulin; Kidney; Malondialdehyde; Muramidase; Rats; Triglycerides

2020
Baicalin suppresses renal fibrosis through microRNA-124/TLR4/NF-κB axis in streptozotocin-induced diabetic nephropathy mice and high glucose-treated human proximal tubule epithelial cells.
    Journal of physiology and biochemistry, 2020, Volume: 76, Issue:3

    Topics: Animals; Cell Line; Diabetic Nephropathies; Epithelial Cells; Fibrosis; Flavonoids; Humans; Kidney; Kidney Tubules, Proximal; Male; Mice; Mice, Inbred C57BL; MicroRNAs; NF-kappa B; Toll-Like Receptor 4

2020
Baicalin attenuates adriamycin-induced nephrotic syndrome by regulating fibrosis procession and inflammatory reaction.
    Genes & genomics, 2021, Volume: 43, Issue:9

    Topics: Animals; Apoptosis; Disease Models, Animal; Doxorubicin; Epithelial-Mesenchymal Transition; Fibrosis; Flavonoids; Gene Expression Regulation; Humans; Inflammation; Kidney; Nephrotic Syndrome; Rats

2021
High doses of baicalin induces kidney injury and fibrosis through regulating TGF-β/Smad signaling pathway.
    Toxicology and applied pharmacology, 2017, 10-15, Volume: 333

    Topics: Actins; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Antiviral Agents; Connective Tissue Growth Factor; Fibronectins; Fibrosis; Flavonoids; Kidney; Kidney Diseases; Rats, Sprague-Dawley; Scutellaria baicalensis; Signal Transduction; Smad3 Protein; Transforming Growth Factor beta1

2017
Baicalin inhibits pressure overload-induced cardiac fibrosis through regulating AMPK/TGF-β/Smads signaling pathway.
    Archives of biochemistry and biophysics, 2018, 02-15, Volume: 640

    Topics: Angiotensin II; Animals; Cells, Cultured; Collagen; Connective Tissue Growth Factor; Dose-Response Relationship, Drug; Fibronectins; Fibrosis; Flavonoids; Heart Diseases; Myocardium; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction; Smad Proteins; Transforming Growth Factor beta

2018
Baicalin inhibits PDGF-BB-induced hepatic stellate cell proliferation, apoptosis, invasion, migration and activation via the miR-3595/ACSL4 axis.
    International journal of molecular medicine, 2018, Volume: 41, Issue:4

    Topics: Animals; Apoptosis; Becaplermin; Cell Proliferation; Coenzyme A Ligases; Enzyme Inhibitors; Fibrosis; Flavonoids; Hepatic Stellate Cells; Liver; MicroRNAs; Plant Extracts; Protective Agents; Proto-Oncogene Proteins c-sis; Rats; Scutellaria baicalensis; Signal Transduction

2018
[Therapeutic effect of baicalin in treatment of renal interstitial fibrosis in rats with unliateral ureteral obstruction and related mechanisms].
    Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2016, Volume: 18, Issue:4

    Topics: Animals; Fibrosis; Flavonoids; Immunohistochemistry; Kidney; Male; Rats; Rats, Sprague-Dawley; Receptor, Notch1; Transforming Growth Factor beta1; Ureteral Obstruction

2016
Baicalin ameliorates renal fibrosis via inhibition of transforming growth factor β1 production and downstream signal transduction.
    Molecular medicine reports, 2017, Volume: 15, Issue:4

    Topics: Animals; Disease Models, Animal; Epithelial-Mesenchymal Transition; Fibrosis; Flavonoids; Immunohistochemistry; Kidney; Kidney Diseases; Male; Models, Biological; Phosphorylation; Rats, Sprague-Dawley; Signal Transduction; Smad Proteins; Transforming Growth Factor beta1; Ureteral Obstruction

2017