baicalin has been researched along with Cerebral Ischemia in 40 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (20.00) | 29.6817 |
| 2010's | 22 (55.00) | 24.3611 |
| 2020's | 10 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cheng, F; Ji, J; Li, Y; Liao, X; Ma, C; Shao, Q; Wang, Q; Wang, X; Xu, T; Xu, W | 1 |
| Cao, H; Liu, JX; Song, WT; Zhang, YH; Zheng, XY | 1 |
| Ci, Z; Cui, M; Guan, Y; Li, N; Liu, S; Long, Y; Shen, L; Wan, J; Xiang, Y; Zhang, Y | 1 |
| Li, S; Li, T; Li, X; Ma, C; Yang, L | 1 |
| Dong, Y; Gao, Y; Guan, T; Li, M; Lv, P; Meng, N; Qi, Q; Teng, Z; Xiao, Y; Xu, J; Yang, X; Zhang, J | 1 |
| He, F; Li, D; Li, N; Liu, S; Long, Y; Shi, A; Wan, J; Yu, S; Zhang, Y | 1 |
| Guo, Y; Li, H; Liu, T; Pan, Y; Wang, D; Wu, L | 1 |
| Ci, Z; Cui, M; Li, N; Long, Y; Lv, X; Xiang, Y; Yang, Q; Zhang, R; Zheng, C | 1 |
| Gong, Z; Kou, J; Liu, B; Liu, K; Song, X | 1 |
| Ci, Z; Cui, M; Li, N; Liu, S; Long, Y; Ni, L; Tang, D; Wan, J; Xiang, Y; Yang, Q; Zhang, Y | 1 |
| Cao, XL; He, WQ; Jia, JX; Wu, FJ; Zhang, QR; Zhao, S; Zheng, WX | 1 |
| Fu, X; Kong, L; Wang, J; Yang, M; Zhang, Q | 1 |
| Li, B; Liu, J; Liu, Q; Ni, X; Wang, P; Wang, Y; Wang, Z; Yu, Y; Zhang, X; Zhang, Y | 1 |
| Cheng, F; Deng, N; Du, W; Fan, S; Li, Z; Lian, Y; Liu, S; Ma, C; Ren, B; Tan, L; Wang, Q; Wang, X; Xu, T; Zhang, S | 1 |
| Kang, YG; Li, M; Shi, YH; Wang, B; Wang, C; Wu, J | 1 |
| Chen, Y; Fang, H; Jing, Z; Liu, J; Lv, A; Meng, F; Wang, Y; Wang, Z; Yu, Y | 1 |
| Duan, CZ; Jia, Q; Li, LY; Liu, P; Zhou, QB | 1 |
| Chang, RC; Chen, X; Gu, Y; Liu, K; Peng, T; Shen, J; So, KF; Xu, M; Yang, D | 1 |
| Cao, XL; Hu, XM; Liu, XY; Pan, HY; Sun, YY; Wang, F; Zheng, WX | 1 |
| Gu, X; Guo, L; He, Q; Liu, X; Liu, Z; Okeke, CI; Tong, L; Yang, H; Zhang, L; Zhang, Q; Zhao, H | 1 |
| Dang, H; Guo, S; Li, B; Li, H; Liu, J; Wang, L; Wang, Y; Wang, Z; Wu, H; Yu, Y; Zhang, Y | 1 |
| Bai, B; Cao, Y; Guo, W; Liu, R; Qi, H; Qu, L; Wang, P; Yu, J; Zhang, Q; Zhu, H | 1 |
| Chen, Y; Kang, R; Li, B; Li, H; Liu, J; Wang, P; Wang, Z; Wu, H; Yu, Y; Zhang, X; Zhang, Y | 1 |
| Kang, RX; Li, B; Liu, J; Wang, PQ; Wang, YY; Wang, Z; Wu, HL; Yu, YN; Zhang, XX; Zhang, YY | 1 |
| Chen, CM; Shi, SS; Tu, XK; Wang, CH; Yang, WZ | 1 |
| Li, P; Liu, F; Wang, Y; Wu, R; Zhang, P; Zhang, W; Zhang, Z | 1 |
| Chen, CM; Chen, Y; Chen, Z; Shi, SS; Tu, XK; Wang, CH; Yang, WZ | 1 |
| Du, L; Hu, J; Lei, F; Li, H; Ma, L; Wang, X; Wang, Y; Xing, D; Yuan, Z | 1 |
| Bu, W; Cheng, F; Jiang, EN; Liu, ZP; Qu, XJ; Sheng, XH; Wang, JH; Xue, X; Yang, Y | 1 |
| Cai, J; Cao, Y; Gao, J; Mao, X; Min, D; Sun, C; Sun, H; Wang, X; Xie, N; Zheng, P | 1 |
| Chen, CM; Chen, JP; Chen, Y; Liang, RS; Ouyang, LQ; Shi, SS; Tu, XK; Wang, CH; Xie, HS; Yang, WZ | 1 |
| Jing, ZW; Li, M; Li, PT; Liu, J; Wang, LY; Wang, Z; Wu, HL; Yan, ZL; Zhang, ZJ; Zhou, CX; Zhou, J | 1 |
| Cheng, K; Cheng, O; Han, Y; Jiang, Q; Li, Z; Yan, Y | 1 |
| Chai, YS; DU, LJ; Hu, J; Lei, F; Li, HY; Wan, HJ; Wang, YG; Xing, DM; Yuan, ZY | 1 |
| Chen, JH; Fan, Y; Li, H; Wang, H; Wang, LH; Zhang, HS | 1 |
| Chang, SF; Hu, SY; Lee, HH; Lee, YH; Wang, CC; Yang, LL | 1 |
| Huang, Y; Liu, JX; Wang, YY; Wang, Z; Wei, CE; Xu, L; Ying, K; Zhang, XY; Zhang, ZJ | 1 |
| Liu, JX; Wang, YY; Wang, Z; Ying, K; Zhang, XY; Zhang, ZJ | 1 |
| Li, PT; Wang, LY; Wang, YY; Wang, Z; Zhang, ZJ | 1 |
| Li, P; Li, PT; Sun, ZH; Wang, YY; Wang, Z; Zhang, WS; Zhang, XJ; Zhang, ZJ | 1 |
40 other study(ies) available for baicalin and Cerebral Ischemia
| Article | Year |
|---|---|
Identification of potential regulating effect of baicalin on NFκB/CCL2/CCR2 signaling pathway in rats with cerebral ischemia by antibody-based array and bioinformatics analysis.
Topics: Animals; Brain Ischemia; Chemokine CCL2; Computational Biology; Flavonoids; Macrophages; Mice; Neuroprotective Agents; NF-kappa B; Nitric Oxide; Phytotherapy; Rats; Rats, Sprague-Dawley; RAW 264.7 Cells; Receptors, CCR2; Reperfusion Injury; Scutellaria baicalensis; Signal Transduction | 2022 |
[Baicalin treats cerebral ischemia reperfusion-induced brain edema in rats by inhibiting TRPV4 and AQP4 of astrocytes].
Topics: Animals; Aquaporin 4; Astrocytes; Brain Edema; Brain Ischemia; Flavonoids; Infarction, Middle Cerebral Artery; Rats; Rats, Sprague-Dawley; Reperfusion; TRPV Cation Channels | 2022 |
Macrophage membrane modified baicalin liposomes improve brain targeting for alleviating cerebral ischemia reperfusion injury.
Topics: Animals; Brain; Brain Ischemia; Flavonoids; Infarction, Middle Cerebral Artery; Liposomes; Macrophages; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2022 |
Preparation of baicalin-loaded ligand-modified nanoparticles for nose-to-brain delivery for neuroprotection in cerebral ischemia.
Topics: Animals; Brain; Brain Ischemia; Cerebral Infarction; Flavonoids; Interleukin-6; Ligands; Nanoparticles; Neuroprotection; Neuroprotective Agents; Polyethylene Glycols; Rats; Tumor Necrosis Factor-alpha | 2022 |
Baicalin facilitates remyelination and suppresses neuroinflammation in rats with chronic cerebral hypoperfusion by activating Wnt/β-catenin and inhibiting NF-κB signaling.
Topics: Animals; Anti-Inflammatory Agents; beta Catenin; Brain Ischemia; Dementia, Vascular; Demyelinating Diseases; Neuroinflammatory Diseases; NF-kappa B; Rats; Remyelination; Wnt Signaling Pathway | 2023 |
Brain targeted borneol-baicalin liposome improves blood-brain barrier integrity after cerebral ischemia-reperfusion injury via inhibiting HIF-1α/VEGF/eNOS/NO signal pathway.
Topics: Animals; Blood-Brain Barrier; Brain; Brain Ischemia; Liposomes; Mice; Reperfusion Injury; Vascular Endothelial Growth Factor A | 2023 |
A protective effect of baicalin on cerebral ischemic rats is related to the improvement of serum progesterone level in serum.
Topics: Animals; Antioxidants; Apoptosis; Brain; Brain Ischemia; Disease Models, Animal; Flavonoids; Glial Fibrillary Acidic Protein; Infarction, Middle Cerebral Artery; Ischemia; Male; Neuroprotective Agents; Rats, Sprague-Dawley | 2019 |
Pharmacokinetics, pharmacodynamics and toxicity of Baicalin liposome on cerebral ischemia reperfusion injury rats via intranasal administration.
Topics: Administration, Intranasal; Animals; Brain; Brain Ischemia; Chromatography, High Pressure Liquid; Female; Flavonoids; Liposomes; Male; Neuroprotective Agents; Rats, Sprague-Dawley; Reperfusion Injury; Tissue Distribution | 2020 |
Baicalin combats glutamate excitotoxicity via protecting glutamine synthetase from ROS-induced 20S proteasomal degradation.
Topics: Animals; Astrocytes; Brain Ischemia; Flavonoids; Glutamate-Ammonia Ligase; Glutamic Acid; Neuroprotective Agents; Proteasome Endopeptidase Complex; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Stroke | 2020 |
Preparation, Characterization and in vivo Study of Borneol-Baicalin-Liposomes for Treatment of Cerebral Ischemia-Reperfusion Injury.
Topics: Animals; Brain; Brain Ischemia; Camphanes; Drug Synergism; Flavonoids; Half-Life; Infarction, Middle Cerebral Artery; Liposomes; Male; Neuroprotective Agents; Phospholipids; Rats, Sprague-Dawley; Reperfusion Injury | 2020 |
Baicalin Inhibits NLRP3 Inflammasome Activity Via the AMPK Signaling Pathway to Alleviate Cerebral Ischemia-Reperfusion Injury.
Topics: AMP-Activated Protein Kinase Kinases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain Ischemia; Cells, Cultured; Flavonoids; Neurons; NLR Family, Pyrin Domain-Containing 3 Protein; Pyroptosis; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction | 2021 |
Treatment Effects of Ischemic Stroke by Berberine, Baicalin, and Jasminoidin from Huang-Lian-Jie-Du-Decoction (HLJDD) Explored by an Integrated Metabolomics Approach.
Topics: Berberine; Brain Ischemia; Drugs, Chinese Herbal; Flavonoids; Humans; Iridoids; Medicine, Chinese Traditional; Metabolomics; Stroke | 2017 |
Network-Wide Screen Identifies Variation of Novel Precise On-Module Targets Using Conformational Modudaoism.
Topics: Allosteric Regulation; Brain Ischemia; Drug Discovery; Flavonoids; Gene Expression Profiling; Gene Regulatory Networks; Humans; Iridoids; Models, Genetic; Ursodeoxycholic Acid | 2018 |
Systematic Understanding of the Mechanism of Baicalin against Ischemic Stroke through a Network Pharmacology Approach.
Topics: Anti-Inflammatory Agents; Antioxidants; Apoptosis; Brain Ischemia; Databases, Genetic; Drugs, Chinese Herbal; Flavonoids; Forkhead Transcription Factors; Humans; Hypoxia-Inducible Factor 1; Mitogen-Activated Protein Kinases; Molecular Docking Simulation; Molecular Structure; NF-kappa B; Phosphatidylinositol 3-Kinases; Phytotherapy; Protein Interaction Maps; Scutellaria baicalensis; Signal Transduction; Stroke | 2018 |
Network pharmacology identification of mechanisms of cerebral ischemia injury amelioration by Baicalin and Geniposide.
Topics: Animals; Arachidonate 5-Lipoxygenase; Brain Ischemia; Cell Line; Cell Polarity; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Interactions; Flavonoids; Humans; Iridoids; Mice; Microglia; Molecular Targeted Therapy; Receptors, Leukotriene | 2019 |
Hierarchical profiles of signaling pathways and networks reveal two complementary pharmacological mechanisms.
Topics: Animals; Brain Ischemia; Flavonoids; Gene Regulatory Networks; Iridoids; Male; Mice; Random Allocation; Signal Transduction; Transcriptome; Ursodeoxycholic Acid | 2013 |
Baicalin attenuates focal cerebral ischemic reperfusion injury by inhibition of protease-activated receptor-1 and apoptosis.
Topics: Animals; Apoptosis; Brain Ischemia; Caspase 3; Flavonoids; Gene Expression Regulation; Male; Rats; Rats, Wistar; Receptor, PAR-1; Reperfusion Injury; RNA, Messenger | 2014 |
Baicalin can scavenge peroxynitrite and ameliorate endogenous peroxynitrite-mediated neurotoxicity in cerebral ischemia-reperfusion injury.
Topics: Animals; Antioxidants; Brain; Brain Ischemia; Cell Line, Tumor; Flavonoids; Humans; Male; Neuroprotective Agents; Nitric Oxide; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxides | 2013 |
Baicalin protects PC-12 cells from oxidative stress induced by hydrogen peroxide via anti-apoptotic effects.
Topics: Animals; Antioxidants; Apoptosis; Blotting, Western; Brain Ischemia; Caspase 3; Cell Survival; Flavonoids; Fluorescent Antibody Technique; Hydrogen Peroxide; Mice; Neuroprotective Agents; Oxidative Stress; Rats | 2014 |
Effect of Baicalin-loaded PEGylated cationic solid lipid nanoparticles modified by OX26 antibody on regulating the levels of baicalin and amino acids during cerebral ischemia-reperfusion in rats.
Topics: Amino Acids; Animals; Antibodies; Brain; Brain Ischemia; Flavonoids; Lipids; Male; Nanoparticles; Polyethylene Glycols; Rats, Sprague-Dawley; Reperfusion Injury | 2015 |
Vertical and Horizontal Convergences of Targeting Pathways in Combination Therapy with Baicalin and Jasminoidin for Cerebral Ischemia.
Topics: Animals; Brain Ischemia; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Therapy, Combination; Flavonoids; Gene Expression; Iridoids; Male; Mice; Microarray Analysis; Random Allocation; Reperfusion Injury | 2016 |
Baicalin alleviates ischemia-induced memory impairment by inhibiting the phosphorylation of CaMKII in hippocampus.
Topics: Animals; Apoptosis; Brain Ischemia; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Flavonoids; Gerbillinae; Hippocampus; Male; Maze Learning; Memory Disorders; Neurons; Neuroprotective Agents; Phosphorylation | 2016 |
Entropy-based divergent and convergent modular pattern reveals additive and synergistic anticerebral ischemia mechanisms.
Topics: Algorithms; Brain; Brain Ischemia; Drug Delivery Systems; Drug Synergism; Drug Therapy, Combination; Entropy; Flavonoids; Gene Ontology; Gene Regulatory Networks; Humans; Iridoids; Neuroprotective Agents; Transcriptome; Ursodeoxycholic Acid | 2016 |
Quantitative Identification of Compound-Dependent On-Modules and Differential Allosteric Modules From Homologous Ischemic Networks.
Topics: Animals; Brain Ischemia; Flavonoids; Gene Expression Profiling; Gene Regulatory Networks; Humans; Iridoids; Mice; Ursodeoxycholic Acid | 2016 |
Neuroprotective effect of baicalin in a rat model of permanent focal cerebral ischemia.
Topics: Animals; Apoptosis; Brain Ischemia; Caspase 3; Cerebral Infarction; Flavonoids; Infarction, Middle Cerebral Artery; Male; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley | 2009 |
Baicalin administration is effective in positive regulation of twenty-four ischemia/reperfusion-related proteins identified by a proteomic study.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis Regulatory Proteins; Blotting, Western; Brain Chemistry; Brain Ischemia; Cell Proliferation; Electrophoresis, Gel, Two-Dimensional; Energy Metabolism; Flavonoids; Hippocampus; Immunohistochemistry; Infarction, Middle Cerebral Artery; Isoelectric Focusing; Male; Mice; Nerve Tissue Proteins; Neurons; Proteomics; Reperfusion Injury; Spectrometry, Mass, Electrospray Ionization | 2009 |
Baicalin inhibits TLR2/4 signaling pathway in rat brain following permanent cerebral ischemia.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Brain Ischemia; Cyclooxygenase 2; Disease Models, Animal; Flavonoids; Infarction, Middle Cerebral Artery; Interleukin-1beta; Male; Neuroprotective Agents; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Toll-Like Receptor 2; Toll-Like Receptor 4; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2011 |
Comprehensive study of baicalin down-regulating NOD2 receptor expression of neurons with oxygen-glucose deprivation in vitro and cerebral ischemia-reperfusion in vivo.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Brain Ischemia; Cell Hypoxia; Cell Line; Cells, Cultured; Cerebral Cortex; Flavonoids; Gene Expression Regulation; Hippocampus; Male; Mice; Mice, Inbred ICR; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Nod2 Signaling Adaptor Protein; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury; RNA, Messenger; Tumor Necrosis Factor-alpha | 2010 |
Baicalin attenuates focal cerebral ischemic reperfusion injury through inhibition of nuclear factor κB p65 activation.
Topics: Animals; Brain Ischemia; Disease Models, Animal; Flavonoids; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; Rats; Rats, Wistar; Reperfusion Injury; Transcription Factor RelA | 2010 |
Baicalin attenuates global cerebral ischemia/reperfusion injury in gerbils via anti-oxidative and anti-apoptotic pathways.
Topics: Animals; Antioxidants; Apoptosis; Brain Ischemia; Brain-Derived Neurotrophic Factor; Caspase 3; Flavonoids; Gerbillinae; Glutathione; Glutathione Peroxidase; Hippocampus; Humans; Male; Malondialdehyde; Molecular Structure; Neurons; Neuroprotective Agents; Reperfusion Injury; RNA, Messenger; Superoxide Dismutase | 2011 |
Effect of baicalin on matrix metalloproteinase-9 expression and blood-brain barrier permeability following focal cerebral ischemia in rats.
Topics: Animals; Blood-Brain Barrier; Brain Edema; Brain Ischemia; Flavonoids; Infarction, Middle Cerebral Artery; Male; Matrix Metalloproteinase 9; Membrane Proteins; Occludin; Permeability; Rats; Rats, Sprague-Dawley | 2011 |
Comparison of the network structural characteristics of calcium signaling pathway in cerebral ischemia after intervention by different components of Chinese medicine.
Topics: Animals; Brain Ischemia; Calcium Signaling; Drugs, Chinese Herbal; Flavonoids; Iridoids; Male; Mice; Nimodipine | 2011 |
Baicalin improved the spatial learning ability of global ischemia/reperfusion rats by reducing hippocampal apoptosis.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Brain Ischemia; Disease Models, Animal; Flavonoids; Hippocampus; In Situ Nick-End Labeling; Learning Disabilities; Male; Maze Learning; Orientation; Rats; Rats, Sprague-Dawley; Reperfusion; Spatial Behavior | 2012 |
Role of baicalin in regulating Toll-like receptor 2/4 after ischemic neuronal injury.
Topics: Animals; Brain Ischemia; Cells, Cultured; Female; Flavonoids; Interleukin-1beta; Male; Mice; Mice, Inbred ICR; Neurons; NF-kappa B; PC12 Cells; Rats; Reperfusion Injury; Toll-Like Receptor 2; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2012 |
Determination of amino acid neurotransmitters in cerebral cortex of rats administered with baicalin prior to cerebral ischemia by capillary electrophoresis-laser-induced fluorescence detection.
Topics: Amino Acids; Animals; Brain Ischemia; Cerebral Cortex; Electrophoresis, Capillary; Flavonoids; Lasers; Male; Neurotransmitter Agents; Rats; Rats, Wistar; Spectrometry, Fluorescence | 2003 |
Differential effects of natural polyphenols on neuronal survival in primary cultured central neurons against glutamate- and glucose deprivation-induced neuronal death.
Topics: Animals; Brain Ischemia; Calcium Signaling; Cell Survival; Cells, Cultured; Central Nervous System; Drugs, Chinese Herbal; Excitatory Amino Acid Agonists; Female; Flavanones; Flavonoids; Glucose; Glutamic Acid; L-Lactate Dehydrogenase; Mitochondria; Nerve Degeneration; Neurons; Neuroprotective Agents; Nitric Oxide; Phenols; Polyphenols; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Scutellaria baicalensis | 2003 |
[The effect of Baicalin on gene expression profile in rat brain of focal cerebral ischemia].
Topics: Animals; Brain Ischemia; Flavonoids; Gene Expression Profiling; Gene Expression Regulation; GTP-Binding Proteins; Male; Oligonucleotide Array Sequence Analysis; Plants, Medicinal; Pyruvate Kinase; Rats; Rats, Sprague-Dawley; RNA, Messenger; Scutellaria; Vimentin | 2004 |
Gene expression profile induced by oral administration of baicalin and gardenin after focal brain ischemia in rats.
Topics: Administration, Oral; Animals; Brain; Brain Ischemia; Flavonoids; Gene Expression Profiling; Gene Expression Regulation; Infarction, Middle Cerebral Artery; Neuroprotective Agents; Oligonucleotide Array Sequence Analysis; Pyridines; Rats; Rats, Sprague-Dawley | 2005 |
[Pharmacological evaluation of baicalin and jasminoidin and their combination on focal cerebral ischemia-reperfusion injury].
Topics: Animals; Behavior, Animal; Brain; Brain Ischemia; CREB-Binding Protein; Cyclic AMP Response Element-Binding Protein; Drug Combinations; Flavonoids; Gardenia; Injections; Iridoids; Male; Neuroprotective Agents; Plants, Medicinal; Proto-Oncogene Proteins c-akt; Pyrans; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Scutellaria; Signal Transduction | 2006 |
A comparative study on the individual and combined effects of baicalin and jasminoidin on focal cerebral ischemia-reperfusion injury.
Topics: Analysis of Variance; Animals; Brain; Brain Ischemia; Brain-Derived Neurotrophic Factor; Caspase 3; Disease Models, Animal; Drug Combinations; Drug Therapy, Combination; Drugs, Chinese Herbal; Flavonoids; Iridoids; Male; Neuroprotective Agents; Nimodipine; Pyrans; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Statistics, Nonparametric | 2006 |