Page last updated: 2024-08-24

baicalin and Acute Liver Injury, Drug-Induced

baicalin has been researched along with Acute Liver Injury, Drug-Induced in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (35.29)29.6817
2010's9 (52.94)24.3611
2020's2 (11.76)2.80

Authors

AuthorsStudies
Gao, X; Huang, W; Jiang, L; Li, S; Liu, W; Wang, K; Wei, Z; Xu, J; Yang, Z; Zhao, H; Zhu, X1
Bai, Q; Hu, F; Huang, Z; Ji, L; Lu, B; Shi, L; Wei, M; Zhang, S; Zhang, T1
Cheng, M; He, P; Liang, Y; Shun, J; Wang, Y; Wu, Y1
Li, S; Qiao, Y; Shang, Z; Wang, S; Wu, Q; Xu, L; Zhang, J; Zhang, Q; Zhang, Y1
Hao, Z; Ji, L; Lu, B; Shi, L; Wang, Z; Wei, M; Zhang, S1
Chen, XJ; Li, K; Nie, H; Shu, KG; Wang, C; Zhang, YX1
Bai, R; Du, S; Wang, H; Wang, M; Zhang, Y1
Chou, AH; Day, YJ; Lee, HC; Liao, CC; Liou, JT; Liu, FC2
Bhadauria, M; Nirala, SK; Wen, YF; Zhao, JQ1
Deng, X; Gao, Z; Huang, Y; Li, H; Xu, Y; Zhang, Y1
Chou, FP; Chu, CY; Hsieh, YS; Hsu, JD; Hwang, JM; Tseng, TH; Wang, CJ1
Gao, Z; Gong, Y; Li, H; Xu, H; Zhao, Y1
Gong, LK; Liu, LL; Qi, XM; Ren, J; Wang, H; Wu, XF; Xiao, Y; Xue, X; Zhang, YH1
Jeon, SJ; Kang, SS; Kim, YS; Lee, CH; Lee, SM; Park, SW; Son, KH1
Gong, X; Li, HZ; Wan, JY; Zhang, L; Zhou, QX; Zhou, YF1
Iwahashi, N; Nose, M; Ogihara, Y; Oguri, K; Terawaki, K1

Other Studies

17 other study(ies) available for baicalin and Acute Liver Injury, Drug-Induced

ArticleYear
Baicalin protects against zearalenone-induced chicks liver and kidney injury by inhibiting expression of oxidative stress, inflammatory cytokines and caspase signaling pathway.
    International immunopharmacology, 2021, Volume: 100

    Topics: Acute Kidney Injury; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Caspases; Chemical and Drug Induced Liver Injury; Chickens; Cytokines; Disease Models, Animal; Flavonoids; Inflammation Mediators; Kidney; Liver; Oxidative Stress; Signal Transduction; Zearalenone

2021
Baicalin promotes liver regeneration after acetaminophen-induced liver injury by inducing NLRP3 inflammasome activation.
    Free radical biology & medicine, 2020, 11-20, Volume: 160

    Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; Flavonoids; Inflammasomes; Liver; Liver Regeneration; Mice; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein

2020
Baicalin Ameliorates Liver Injury Induced by Chronic plus Binge Ethanol Feeding by Modulating Oxidative Stress and Inflammation via CYP2E1 and NRF2 in Mice.
    Oxidative medicine and cellular longevity, 2017, Volume: 2017

    Topics: Animals; Anti-Infective Agents; Binge Drinking; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Ethanol; Female; Flavonoids; Inflammation; Liver; Male; Mice; NF-E2-Related Factor 2; Oxidative Stress

2017
Multiple perspectives of qingkailing injection-fraction-single compound in revealing the hepatotoxicity of baicalin and hyodeoxycholic acid.
    Journal of ethnopharmacology, 2018, Apr-06, Volume: 215

    Topics: Biomarkers; Chemical and Drug Induced Liver Injury; Deoxycholic Acid; Drugs, Chinese Herbal; Flavonoids; Hep G2 Cells; Humans; Quality Control

2018
Baicalein and baicalin alleviate acetaminophen-induced liver injury by activating Nrf2 antioxidative pathway: The involvement of ERK1/2 and PKC.
    Biochemical pharmacology, 2018, Volume: 150

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Antioxidants; Cell Line; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Enzyme Activators; Flavanones; Flavonoids; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Oxidative Stress; Protein Kinase C; Protein Kinase Inhibitors

2018
[Protective effect of baicalin solid dispersion on D-galactosamine induced acute hepatic injury in mice].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2014, Volume: 34, Issue:1

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Flavonoids; Galactosamine; Male; Malondialdehyde; Mice; Mice, Inbred Strains; Protective Agents; Superoxide Dismutase

2014
Baicalin Attenuates Alcoholic Liver Injury through Modulation of Hepatic Oxidative Stress, Inflammation and Sonic Hedgehog Pathway in Rats.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2016, Volume: 39, Issue:3

    Topics: Animals; Apoptosis; Cell Line; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Ethanol; Flavonoids; Gene Expression Regulation; Glutathione Peroxidase; Hedgehog Proteins; Hepatocytes; Humans; Interleukin-1beta; Interleukin-6; Liver; Liver Diseases, Alcoholic; Liver Function Tests; Male; Malondialdehyde; Patched-1 Receptor; Protective Agents; Rats; Rats, Wistar; Scutellaria baicalensis; Signal Transduction; Smoothened Receptor; Superoxide Dismutase; Tumor Necrosis Factor-alpha; Zinc Finger Protein GLI1

2016
Baicalin Attenuates IL-17-Mediated Acetaminophen-Induced Liver Injury in a Mouse Model.
    PloS one, 2016, Volume: 11, Issue:11

    Topics: Acetaminophen; Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Flavonoids; Flow Cytometry; Immunohistochemistry; Interleukin-17; Interleukin-6; Liver; Liver Regeneration; Male; Malondialdehyde; Mice, Inbred C57BL; Peroxidase; Receptors, Antigen, T-Cell, gamma-delta; Superoxide Dismutase; T-Lymphocytes; Tumor Necrosis Factor-alpha

2016
ERK Signaling Pathway Plays a Key Role in Baicalin Protection Against Acetaminophen-Induced Liver Injury.
    The American journal of Chinese medicine, 2017, Volume: 45, Issue:1

    Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Drug Overdose; Flavonoids; Interleukin-6; Liver; MAP Kinase Signaling System; Mice; Peroxidase; Tumor Necrosis Factor-alpha

2017
Baicalin prevents cadmium induced hepatic cytotoxicity, oxidative stress and histomorphometric alterations.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2013, Volume: 65, Issue:1-2

    Topics: Animals; Antioxidants; Cadmium Chloride; Cell Line; Cell Proliferation; Cell Survival; Chemical and Drug Induced Liver Injury; Drugs, Chinese Herbal; Flavonoids; Humans; Liver; Liver Function Tests; Male; Oxidative Stress; Rats; Rats, Wistar

2013
Iron overload-induced rat liver injury: Involvement of protein tyrosine nitration and the effect of baicalin.
    European journal of pharmacology, 2012, Apr-05, Volume: 680, Issue:1-3

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Flavonoids; Glutathione Peroxidase; Glutathione Transferase; Iron; Iron Overload; Liver; Male; Nitrosation; Oxidation-Reduction; Oxidative Stress; Protein Carbonylation; Protein Processing, Post-Translational; Rats; Rats, Wistar; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Tyrosine

2012
Protective effect of baicalin on tert-butyl hydroperoxide-induced rat hepatotoxicity.
    Archives of toxicology, 2005, Volume: 79, Issue:2

    Topics: Animals; Antioxidants; Cell Survival; Cells, Cultured; Chemical and Drug Induced Liver Injury; DNA Damage; DNA Repair; Flavonoids; Glutathione; Hepatitis, Animal; Hepatocytes; Lipid Peroxidation; Liver; Male; Rats; Rats, Sprague-Dawley; tert-Butylhydroperoxide

2005
Effects of flavonoids extracted from Scutellaria baicalensis Georgi on hemin-nitrite-H2O2 induced liver injury.
    European journal of pharmacology, 2006, Apr-24, Volume: 536, Issue:1-2

    Topics: Animals; Cell Line, Tumor; Cell Survival; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Flavanones; Flavonoids; Glutathione; Hemin; Humans; Hydrogen Peroxide; Lipid Peroxidation; Liver; Liver Diseases; Microsomes, Liver; Nitrates; Nitrites; Nitrosation; Oxidation-Reduction; Plant Extracts; Proteins; Rats; Scutellaria baicalensis

2006
Baicalin protects mouse from Concanavalin A-induced liver injury through inhibition of cytokine production and hepatocyte apoptosis.
    Liver international : official journal of the International Association for the Study of the Liver, 2007, Volume: 27, Issue:4

    Topics: Animals; Apoptosis; Chemical and Drug Induced Liver Injury; Concanavalin A; Cytokines; Flavonoids; Hepatocytes; Mice; Mice, Inbred Strains; Protective Agents; T-Lymphocytes; Treatment Outcome; Tumor Necrosis Factor-alpha

2007
Protective effect of baicalin against carbon tetrachloride-induced acute hepatic injury in mice.
    Journal of pharmacological sciences, 2008, Volume: 106, Issue:1

    Topics: Animals; Antioxidants; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cyclooxygenase 2; Disease Models, Animal; Dose-Response Relationship, Drug; Flavonoids; Glutathione; Heme Oxygenase-1; Lipid Peroxidation; Liver; Liver Diseases; Male; Membrane Proteins; Mice; Mice, Inbred ICR; Nitric Oxide Synthase Type II; Oxidative Stress; RNA, Messenger; Time Factors; Transaminases; Tumor Necrosis Factor-alpha

2008
Protective effect of baicalin against lipopolysaccharide/D-galactosamine-induced liver injury in mice by up-regulation of heme oxygenase-1.
    European journal of pharmacology, 2008, Jun-10, Volume: 587, Issue:1-3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Chemical and Drug Induced Liver Injury; Flavonoids; Galactosamine; Heme Oxygenase-1; Lipopolysaccharides; Liver; Mice; Mice, Inbred BALB C; Peroxidase; Reverse Transcriptase Polymerase Chain Reaction; Tumor Necrosis Factor-alpha; Up-Regulation

2008
Comparative study of the high molecular mass fraction and low molecular mass fraction of Sho-saiko-to in a murine immunologically induced liver injury model.
    Biological & pharmaceutical bulletin, 2002, Volume: 25, Issue:1

    Topics: Animals; BCG Vaccine; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavonoids; Glycyrrhizic Acid; Lipopolysaccharides; Male; Mice; Mice, Inbred ICR; Molecular Weight; Nitric Oxide; Shock, Septic

2002