bafilomycin-a and HIV-Infections

bafilomycin-a has been researched along with HIV-Infections* in 1 studies

Other Studies

1 other study(ies) available for bafilomycin-a and HIV-Infections

Article	Year
Chloroquine mediated molecular tuning of astrocytes for enhanced permissiveness to HIV infection. Virology, 2008, Nov-10, Volume: 381, Issue:1 We report in this study that minimum productive HIV infection in astrocytes (a predominant cell type in brain and persists for the entire life) occurs through endocytosis. The lysosomotropic agent chloroquine enhanced permissiveness of astrocytes to HIV infection possibly by circumventing degradation of endosome-entrapped viral particles. In particular, chloroquine may promote establishment of a stable long term viral reservoir in astrocytes and may eventually facilitate early onset of neurological complications. Topics: Antirheumatic Agents; Astrocytes; Brain; Cells, Cultured; Chloroquine; Enzyme Inhibitors; HIV; HIV Infections; Humans; Jurkat Cells; Macrolides	2008

Article

Year

Chloroquine mediated molecular tuning of astrocytes for enhanced permissiveness to HIV infection.

Virology, 2008, Nov-10, Volume: 381, Issue:1

We report in this study that minimum productive HIV infection in astrocytes (a predominant cell type in brain and persists for the entire life) occurs through endocytosis. The lysosomotropic agent chloroquine enhanced permissiveness of astrocytes to HIV infection possibly by circumventing degradation of endosome-entrapped viral particles. In particular, chloroquine may promote establishment of a stable long term viral reservoir in astrocytes and may eventually facilitate early onset of neurological complications.

Topics: Antirheumatic Agents; Astrocytes; Brain; Cells, Cultured; Chloroquine; Enzyme Inhibitors; HIV; HIV Infections; Humans; Jurkat Cells; Macrolides

2008