baclofen has been researched along with Tinnitus in 8 studies
Tinnitus: A nonspecific symptom of hearing disorder characterized by the sensation of buzzing, ringing, clicking, pulsations, and other noises in the ear. Objective tinnitus refers to noises generated from within the ear or adjacent structures that can be heard by other individuals. The term subjective tinnitus is used when the sound is audible only to the affected individual. Tinnitus may occur as a manifestation of COCHLEAR DISEASES; VESTIBULOCOCHLEAR NERVE DISEASES; INTRACRANIAL HYPERTENSION; CRANIOCEREBRAL TRAUMA; and other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine the effectiveness of baclofen in ameliorating tinnitus in adult patients." | 9.08 | A double-blind placebo-controlled trial of baclofen in the treatment of tinnitus. ( Roberson, JB; Stach, BA; Westerberg, BD, 1996) |
| "The first case concerns a 60-year-old man who reported tinnitus when he reached a 180 mg/d dose of baclofen after 3 months of treatment." | 7.80 | Severe tinnitus induced by off-label baclofen. ( Auffret, M; Bordet, R; Cottencin, O; Deheul, S; Gautier, S; Hennaux, C; Loche, V; Rolland, B, 2014) |
| "Subjective tinnitus is a chronic neurological disorder in which phantom sounds are perceived." | 5.40 | Effects of early and late treatment with L-baclofen on the development and maintenance of tinnitus caused by acoustic trauma in rats. ( McPherson, K; Smith, PF; Zheng, Y, 2014) |
| "Subjective tinnitus is a chronic neurological disorder in which phantom sounds are perceived." | 5.38 | A dose-response analysis of the effects of L-baclofen on chronic tinnitus caused by acoustic trauma in rats. ( Darlington, CL; McNamara, E; Smith, PF; Vagal, S; Zheng, Y, 2012) |
| "(-)-Baclofen was the only one of the three compounds tested that reversed in a dose-dependent manner the effects of tone exposure on both the amplitude of the click-evoked potentials recorded from the IC and on measures of the changes in temporal integration based on these potentials." | 5.29 | Effects of (-)-baclofen, clonazepam, and diazepam on tone exposure-induced hyperexcitability of the inferior colliculus in the rat: possible therapeutic implications for pharmacological management of tinnitus and hyperacusis. ( Møller, AR; Szczepaniak, WS, 1996) |
| "To determine the effectiveness of baclofen in ameliorating tinnitus in adult patients." | 5.08 | A double-blind placebo-controlled trial of baclofen in the treatment of tinnitus. ( Roberson, JB; Stach, BA; Westerberg, BD, 1996) |
| "The first case concerns a 60-year-old man who reported tinnitus when he reached a 180 mg/d dose of baclofen after 3 months of treatment." | 3.80 | Severe tinnitus induced by off-label baclofen. ( Auffret, M; Bordet, R; Cottencin, O; Deheul, S; Gautier, S; Hennaux, C; Loche, V; Rolland, B, 2014) |
| "Tinnitus is the perception of phantom sounds, a phenomenon believed to be due to abnormal neuronal activity in auditory regions of the CNS such as the brainstem cochlear nucleus (CN)." | 1.42 | Glutamic acid decarboxylase levels in the cochlear nucleus of rats with acoustic trauma-induced chronic tinnitus. ( Dixon, S; MacPherson, K; McPherson, K; Smith, PF; Zheng, Y, 2015) |
| "Subjective tinnitus is a chronic neurological disorder in which phantom sounds are perceived." | 1.40 | Effects of early and late treatment with L-baclofen on the development and maintenance of tinnitus caused by acoustic trauma in rats. ( McPherson, K; Smith, PF; Zheng, Y, 2014) |
| "Subjective tinnitus is a chronic neurological disorder in which phantom sounds are perceived." | 1.38 | A dose-response analysis of the effects of L-baclofen on chronic tinnitus caused by acoustic trauma in rats. ( Darlington, CL; McNamara, E; Smith, PF; Vagal, S; Zheng, Y, 2012) |
| "The very rare case of palatal myoclonus manifesting in objective tinnitus was discussed." | 1.31 | [A case of objective tinnitus caused by palatal myoclonus]. ( Nowak, K; Szyfter, W, 2001) |
| "(-)-Baclofen was the only one of the three compounds tested that reversed in a dose-dependent manner the effects of tone exposure on both the amplitude of the click-evoked potentials recorded from the IC and on measures of the changes in temporal integration based on these potentials." | 1.29 | Effects of (-)-baclofen, clonazepam, and diazepam on tone exposure-induced hyperexcitability of the inferior colliculus in the rat: possible therapeutic implications for pharmacological management of tinnitus and hyperacusis. ( Møller, AR; Szczepaniak, WS, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zheng, Y | 3 |
| McPherson, K | 2 |
| Smith, PF | 3 |
| Auffret, M | 1 |
| Rolland, B | 1 |
| Deheul, S | 1 |
| Loche, V | 1 |
| Hennaux, C | 1 |
| Cottencin, O | 1 |
| Bordet, R | 1 |
| Gautier, S | 1 |
| Dixon, S | 1 |
| MacPherson, K | 1 |
| Vagal, S | 1 |
| McNamara, E | 1 |
| Darlington, CL | 1 |
| Szczepaniak, WS | 1 |
| Møller, AR | 1 |
| Westerberg, BD | 1 |
| Roberson, JB | 1 |
| Stach, BA | 1 |
| Moller, AR | 1 |
| Nowak, K | 1 |
| Szyfter, W | 1 |
2 trials available for baclofen and Tinnitus
| Article | Year |
|---|---|
A double-blind placebo-controlled trial of baclofen in the treatment of tinnitus.
Topics: Adult; Aged; Baclofen; Double-Blind Method; Female; Hearing Loss, Sensorineural; Humans; Loudness Pe | 1996 |
A double-blind placebo-controlled trial of baclofen in the treatment of tinnitus.
Topics: Baclofen; Double-Blind Method; Humans; Muscle Relaxants, Central; Placebos; Tinnitus | 1997 |
6 other studies available for baclofen and Tinnitus
| Article | Year |
|---|---|
Effects of early and late treatment with L-baclofen on the development and maintenance of tinnitus caused by acoustic trauma in rats.
Topics: Acoustic Stimulation; Animals; Baclofen; Cochlear Nucleus; Conditioning, Psychological; Evoked Poten | 2014 |
Severe tinnitus induced by off-label baclofen.
Topics: Alcoholism; Baclofen; Dose-Response Relationship, Drug; Female; GABA-B Receptor Agonists; Humans; Ma | 2014 |
Glutamic acid decarboxylase levels in the cochlear nucleus of rats with acoustic trauma-induced chronic tinnitus.
Topics: Animals; Baclofen; Chronic Disease; Cochlear Nucleus; GABA-B Receptor Agonists; Glutamate Decarboxyl | 2015 |
A dose-response analysis of the effects of L-baclofen on chronic tinnitus caused by acoustic trauma in rats.
Topics: Animals; Baclofen; Behavior, Animal; Dose-Response Relationship, Drug; Evoked Potentials, Auditory, | 2012 |
Effects of (-)-baclofen, clonazepam, and diazepam on tone exposure-induced hyperexcitability of the inferior colliculus in the rat: possible therapeutic implications for pharmacological management of tinnitus and hyperacusis.
Topics: Acoustic Stimulation; Animals; Auditory Threshold; Baclofen; Clonazepam; Diazepam; Disease Models, A | 1996 |
[A case of objective tinnitus caused by palatal myoclonus].
Topics: Baclofen; Child; Humans; Male; Muscle Relaxants, Central; Myoclonus; Tinnitus | 2001 |