baclofen has been researched along with Stiff-Person Syndrome in 28 studies
Stiff-Person Syndrome: A condition characterized by persistent spasms (SPASM) involving multiple muscles, primarily in the lower limbs and trunk. The illness tends to occur in the fourth to sixth decade of life, presenting with intermittent spasms that become continuous. Minor sensory stimuli, such as noise and light touch, precipitate severe spasms. Spasms do not occur during sleep and only rarely involve cranial muscles. Respiration may become impaired in advanced cases. (Adams et al., Principles of Neurology, 6th ed, p1492; Neurology 1998 Jul;51(1):85-93)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Intrathecal baclofen (ITB) is used for unresponsiveness to other treatment for patients with stiff-person syndrome (SPS)." | 7.72 | Intrathecal baclofen for stiff-person syndrome: life-threatening intermittent catheter leakage. ( Bardutzky, J; Meinck, HM; Schwab, S; Tronnier, V, 2003) |
| "Intrathecal baclofen (ITB) is used for unresponsiveness to other treatment for patients with stiff-person syndrome (SPS)." | 3.72 | Intrathecal baclofen for stiff-person syndrome: life-threatening intermittent catheter leakage. ( Bardutzky, J; Meinck, HM; Schwab, S; Tronnier, V, 2003) |
| " They also required higher doses and more rapid dosage increases." | 2.68 | Intrathecal baclofen therapy for stiff-man syndrome and progressive encephalomyelopathy with rigidity and myoclonus. ( Dressnandt, J; Marquardt, G; Mauch, E; Meinck, HM; Müller-Schwefe, G; Rieke, K; Schumm, F; Stayer, C; Tronnier, V, 1997) |
| "A 49-year-old male with type 1 diabetes presented with a 6-month history of muscle rigidity and spasms of his upper and lower extremities." | 2.46 | Stiff-person syndrome: a case report and review of the literature. ( Chedebeau, F; Egwuonwu, S, 2010) |
| "This is the youngest case of sporadic Stiffman syndrome reported in literature." | 2.40 | Sporadic Stiffman syndrome in a young girl. ( Dharnidharka, VR; Gajendragadkar, AR; Udani, SV; Udani, VP, 1997) |
| "However, unusual symptoms such as myoclonus can occur in few cases and together with the rarity of the condition, the prevalence of misdiagnosis is high." | 1.51 | Stiff limb syndrome with lower limb myoclonus: A case report. ( Chen, J; Feng, YY; Li, LL; Zhang, CG, 2019) |
| "It is characterized by muscle spasms triggered by startle, voluntary movement, or tactile or emotional stimuli, occurring predominantly in the axial musculature." | 1.37 | Stiff person syndrome and pregnancy. ( Blaskiewicz, R; Goldkamp, J; Myles, T, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (35.71) | 18.2507 |
| 2000's | 8 (28.57) | 29.6817 |
| 2010's | 7 (25.00) | 24.3611 |
| 2020's | 3 (10.71) | 2.80 |
| Authors | Studies |
|---|---|
| Dalakas, MC | 1 |
| Zhang, CG | 1 |
| Li, LL | 1 |
| Feng, YY | 1 |
| Chen, J | 1 |
| Oh, DC | 1 |
| Rakesh, N | 1 |
| LaGrant, B | 1 |
| Sein, M | 1 |
| Cai, Q | 1 |
| Wu, C | 1 |
| Xu, W | 1 |
| Liang, Y | 1 |
| Liao, S | 1 |
| Abbatemarco, JR | 1 |
| Willis, MA | 1 |
| Wilson, RG | 1 |
| Nagel, SJ | 1 |
| Machado, AG | 1 |
| Bethoux, FA | 1 |
| Derksen, A | 1 |
| Stettner, M | 1 |
| Stöcker, W | 1 |
| Seitz, RJ | 2 |
| Tohid, H | 1 |
| Saigal, R | 1 |
| Goyal, L | 1 |
| Yadav, R | 1 |
| Agrawal, A | 1 |
| Mital, P | 1 |
| Patel, B | 1 |
| Ho, BL | 1 |
| Shih, PY | 1 |
| Egwuonwu, S | 1 |
| Chedebeau, F | 1 |
| Goldkamp, J | 1 |
| Blaskiewicz, R | 1 |
| Myles, T | 1 |
| Bardutzky, J | 1 |
| Tronnier, V | 3 |
| Schwab, S | 2 |
| Meinck, HM | 4 |
| Vogels, RL | 1 |
| van Orshoven, NP | 1 |
| de Koning-Tijssen, MA | 1 |
| Wouda, EJ | 1 |
| Weatherby, SJM | 1 |
| Woolner, P | 1 |
| Clarke, CE | 1 |
| Hattan, E | 1 |
| Angle, MR | 1 |
| Chalk, C | 1 |
| Vernino, S | 1 |
| McEvoy, K | 1 |
| Silbert, PL | 1 |
| Matsumoto, JY | 1 |
| McManis, PG | 1 |
| Stolp-Smith, KA | 1 |
| Elliott, BA | 1 |
| McEvoy, KM | 1 |
| Rieke, K | 2 |
| Wirtz, CR | 1 |
| Flügel, D | 1 |
| Ford, B | 1 |
| Fahn, S | 1 |
| Ricker, K | 1 |
| Hülser, PJ | 1 |
| Schmid, E | 1 |
| Peiffer, J | 1 |
| Solimena, M | 1 |
| Penn, RD | 1 |
| Mangieri, EA | 1 |
| Blank, B | 1 |
| Kiwit, JC | 1 |
| Benecke, R | 1 |
| Diedrich, U | 1 |
| Udani, VP | 1 |
| Dharnidharka, VR | 1 |
| Gajendragadkar, AR | 1 |
| Udani, SV | 1 |
| Stayer, C | 1 |
| Dressnandt, J | 1 |
| Mauch, E | 1 |
| Marquardt, G | 1 |
| Müller-Schwefe, G | 1 |
| Schumm, F | 1 |
| Gouider-Khouja, N | 1 |
| Mekaouar, A | 1 |
| Larnaout, A | 1 |
| Miladi, N | 1 |
| Ben Khelifa, F | 1 |
| Hentati, F | 1 |
| Calvet, D | 1 |
| Touzé, E | 1 |
| Delegue, P | 1 |
| Bertherat, J | 1 |
| Zuber, M | 1 |
| Clifton, ER | 1 |
| Subramony, SH | 1 |
5 reviews available for baclofen and Stiff-Person Syndrome
| Article | Year |
|---|---|
Therapies in Stiff-Person Syndrome: Advances and Future Prospects Based on Disease Pathophysiology.
Topics: Aged; Autoantibodies; Autoimmunity; Baclofen; Child; Female; Humans; Spasm; Stiff-Person Syndrome | 2023 |
Anti-glutamic acid decarboxylase antibody positive neurological syndromes.
Topics: Autoantibodies; Baclofen; Cerebellar Ataxia; Diazepam; Epilepsy; GABA Modulators; GABA-B Receptor Ag | 2016 |
Stiff-person syndrome: a case report and review of the literature.
Topics: Anemia, Pernicious; Anti-Anxiety Agents; Baclofen; Diabetes Mellitus, Type 1; Diagnosis, Differentia | 2010 |
Stiff-person syndrome with anti-glutamic acid decarboxylase autoantibodies: complete remission of symptoms after intrathecal baclofen administration.
Topics: Autoantibodies; Baclofen; Diabetes Mellitus, Type 1; Female; Glutamate Decarboxylase; Humans; Inject | 1995 |
Sporadic Stiffman syndrome in a young girl.
Topics: Baclofen; Diagnosis, Differential; Diazepam; Drug Therapy, Combination; Female; GABA Agonists; GABA | 1997 |
2 trials available for baclofen and Stiff-Person Syndrome
| Article | Year |
|---|---|
Intrathecal baclofen therapy in stiff-man syndrome: a double-blind, placebo-controlled trial.
Topics: Analysis of Variance; Baclofen; Double-Blind Method; Electromyography; Humans; Injections, Spinal; R | 1995 |
Intrathecal baclofen therapy for stiff-man syndrome and progressive encephalomyelopathy with rigidity and myoclonus.
Topics: Adult; Aged; Baclofen; Central Nervous System Diseases; Cohort Studies; Disease Progression; Female; | 1997 |
21 other studies available for baclofen and Stiff-Person Syndrome
| Article | Year |
|---|---|
Stiff limb syndrome with lower limb myoclonus: A case report.
Topics: Baclofen; Botulinum Toxins, Type A; Diagnosis, Differential; Electromyography; Humans; Immunoglobuli | 2019 |
Advanced Progression of Scoliosis After Intrathecal Baclofen in an Adult With Stiff Person Syndrome: A Case Report.
Topics: Adult; Baclofen; Child; Humans; Scoliosis; Stiff-Person Syndrome | 2020 |
Stiff-person syndrome coexisting with critical illness polyneuropathy: A case report.
Topics: Baclofen; Clonazepam; Diagnosis, Differential; Electromyography; Humans; Immunoglobulins, Intravenou | 2020 |
Case Series: Intrathecal Baclofen Therapy in Stiff-Person Syndrome.
Topics: Adult; Aged; Baclofen; Female; Follow-Up Studies; Humans; Injections, Spinal; Male; Middle Aged; Mus | 2018 |
Antiglycine receptor-related stiff limb syndrome in a patient with chronic lymphocytic leukaemia.
Topics: Aged; Autoantibodies; Baclofen; Clonazepam; Electromyography; GABA Agents; Humans; Leukemia, Lymphoc | 2013 |
Stiff Person Syndrome.
Topics: Adult; Antibodies; Anticonvulsants; Autoimmunity; Baclofen; Clonazepam; Electromyography; Glutamate | 2015 |
Successful intrathecal baclofen therapy for seronegative stiff-person syndrome: a case report.
Topics: Adult; Autoantibodies; Baclofen; Glutamate Decarboxylase; Humans; Injections, Spinal; Male; Stiff-Pe | 2008 |
Stiff person syndrome and pregnancy.
Topics: Adult; Amines; Baclofen; Cesarean Section; Cyclohexanecarboxylic Acids; Diazepam; Female; Gabapentin | 2011 |
Intrathecal baclofen for stiff-person syndrome: life-threatening intermittent catheter leakage.
Topics: Acute Disease; Adult; Baclofen; Catheterization; Equipment Failure; Humans; Hypertension; Infusion P | 2003 |
['Stiff-person'-syndrome].
Topics: Adrenal Cortex Hormones; Autoantibodies; Baclofen; Diazepam; Electromyography; Female; Glutamate Dec | 2003 |
Pregnancy in stiff-limb syndrome.
Topics: Adult; Anti-Inflammatory Agents; Anticonvulsants; Baclofen; Diazepam; Drug Therapy, Combination; Ext | 2004 |
Unexpected benefit of propofol in stiff-person syndrome.
Topics: Aged; Autoantibodies; Baclofen; Diazepam; Drug Resistance; Female; GABA Agonists; GABA-A Receptor Ag | 2008 |
Propofol for stiff-person syndrome: learning new tricks from an old dog.
Topics: Aged; Autoantibodies; Baclofen; Diazepam; Drug Resistance; Female; GABA Agonists; GABA-A Receptor Ag | 2008 |
Intrathecal baclofen treatment for stiff-man syndrome: pump failure may be fatal.
Topics: Aged; Baclofen; Equipment Failure; Female; Humans; Infusion Pumps; Stiff-Person Syndrome | 1994 |
Intrathecal baclofen.
Topics: Baclofen; Double-Blind Method; Female; Humans; Injections, Spinal; Middle Aged; Stiff-Person Syndrom | 1994 |
Stiff man syndrome: clinical and laboratory findings in eight patients.
Topics: Adult; Aged; Autoantibodies; Autoimmune Diseases; Baclofen; Benzodiazepines; Blood Proteins; Central | 1994 |
Stiff-man syndrome treated with intrathecal baclofen.
Topics: Adult; Baclofen; Female; Humans; Injections, Spinal; Male; Middle Aged; Stiff-Person Syndrome | 1993 |
[Rhythmic circulatory dysregulation in stiff man syndrome].
Topics: Autonomic Nervous System; Baclofen; Blood Pressure; Cardiovascular System; Female; GABA Agonists; ga | 1996 |
Progressive encephalomyelitis with rigidity presenting as a stiff-person syndrome.
Topics: Anti-Inflammatory Agents; Baclofen; Diagnosis, Differential; Diazepam; Drug Therapy, Combination; El | 2002 |
[Stiff limb syndrome associated with Hashimoto's encephalopathy: improvement after corticotherapy].
Topics: Aged; Antibody Specificity; Anticonvulsants; Antithyroid Agents; Autoantibodies; Autoimmune Diseases | 2002 |
Stiff-man syndrome.
Topics: Adult; Baclofen; Diazepam; Female; Humans; Male; Middle Aged; Stiff-Person Syndrome | 1992 |