Page last updated: 2024-10-23

baclofen and Spasm

baclofen has been researched along with Spasm in 68 studies

Spasm: An involuntary contraction of a muscle or group of muscles. Spasms may involve SKELETAL MUSCLE or SMOOTH MUSCLE.

Research Excerpts

ExcerptRelevanceReference
"We tested the hypothesis that changes in soleus stretch reflex was correlated to changes in intrathecal baclofen dose in 12 multiple sclerosis patients with moderate-severe spasticity treated with intrathecal baclofen pump."9.11Guided intrathecal baclofen administration by using soleus stretch reflex in moderate-severe spastic multiple sclerosis patients with implanted pump. ( Nielsen, JF; Sinkjaer, T, 2004)
"Stroke patients with >6 months of intractable spasticity were screened via a randomized, double-blind, placebo-controlled crossover design of either intrathecal normal saline or 50 microgram baclofen."9.09Intrathecal baclofen for spastic hypertonia from stroke. ( Brunner, RC; Guin-Renfroe, S; Hadley, MN; Meythaler, JM, 2001)
" baclofen on spontaneous and evoked (allodynia) dysesthetic pain suggests that a dysfunctional spinal gamma-aminobutyric acidB receptor system, including functional supersensitivity, is associated with the phenomenon of central pain among patients with spinal lesions."9.07Intrathecal baclofen suppresses central pain in patients with spinal lesions. A pilot study. ( D'Luzansky, SC; Herman, RM; Ippolito, R, 1992)
"Spasms in patients with generalized tetanus can be suppressed by a spinal intrathecal infusion of baclofen."8.79Intrathecal baclofen in tetanus: four cases and a review of reported cases. ( Dressnandt, J; Klingelhöfer, J; Konstanzer, A; Pfab, R; Weinzierl, FX, 1997)
"A retrospective chart review was performed of patients with cerebral palsy undergoing single event, multilevel lower extremity surgery at a single institution who received epidural analgesia with or without continuous baclofen infusion."7.81Epidural Baclofen for the Management of Postoperative Pain in Children With Cerebral Palsy. ( Halanski, MA; Montero, RJ; Nemeth, BA; Noonan, KJ, 2015)
"We report on the case of a patient suffering from Friedreich's ataxia (FA) with very painful and disabling spasms that were improved markedly by intrathecal baclofen infusion."7.73Intrathecal baclofen in the treatment of painful, disabling spasms in Friedreich's ataxia. ( Ben Smail, D; Bussel, B; Denys, P; Jacq, C, 2005)
"Intrathecal baclofen (ITB) is used for unresponsiveness to other treatment for patients with stiff-person syndrome (SPS)."7.72Intrathecal baclofen for stiff-person syndrome: life-threatening intermittent catheter leakage. ( Bardutzky, J; Meinck, HM; Schwab, S; Tronnier, V, 2003)
"To measure the effect of baclofen on the transmission in different spinal pathways to soleus motoneurones in spastic multiple sclerosis patients."7.70The effect of baclofen on the transmission in spinal pathways in spastic multiple sclerosis patients. ( Crone, C; Krarup, C; Nielsen, J; Orsnes, G; Petersen, N, 2000)
"In this case study we describe a dual approach to the palliation of difficult muscle spasms using intrathecal baclofen via a fully implanted system, together with the homeopathic approach to symptom control."7.70Intrathecal baclofen and homeopathy for the treatment of painful muscle spasms associated with malignant spinal cord compression. ( Hicks, F; Thompson, E, 1998)
"This study reports the use of intrathecal baclofen in two ventilator-dependent children with severe spasms secondary to spinal-cord injury."7.68Continuous intrathecal baclofen treatment of severe spasms in two children with spinal-cord injury. ( Armstrong, RW; Cochrane, D; Farrell, K; Kube, S; Norman, MG; Steinbok, P, 1992)
"A 58-year-old woman with long-standing hemifacial spasm experienced dramatic relief of symptomatology while receiving baclofen (Lioresal) in a daily dosage of 37."7.67Baclofen in hemifacial spasm. ( Sandyk, R, 1984)
"Six patients with idiopathic hemifacial spasm refractory to the usually employed medications were successfully treated with baclofen."7.67Baclofen in hemifacial spasm. ( Gillman, MA; Sandyk, R, 1987)
"The current strategies involved in treating tetanus are discussed."6.43Tetanus in a subcutaneous drug abuser: ineffectiveness of intrathecal baclofen. ( Bellamy, MC; Thomas, RM, 2006)
"Baclofen is the most commonly-prescribed antispasmodic after SCI."5.41Intrathecal and Oral Baclofen Use in Adults With Spinal Cord Injury: A Systematic Review of Efficacy in Spasticity Reduction, Functional Changes, Dosing, and Adverse Events. ( D'Amico, JM; Dietz, N; Harkema, SJ; Wagers, S, 2023)
"Ten patients with severe spasticity were evaluated according to a standardized protocol in order to be treated by intraspinal baclofen."5.28Intraspinal baclofen in the treatment of severe spasticity and spasms. ( Closa, C; Garcia-Fernandez, L; Guitart, JM; Jodar, R; Muxi, T; Noguer, M; Rubio, E; Sahuquillo, J, 1991)
"We tested the hypothesis that changes in soleus stretch reflex was correlated to changes in intrathecal baclofen dose in 12 multiple sclerosis patients with moderate-severe spasticity treated with intrathecal baclofen pump."5.11Guided intrathecal baclofen administration by using soleus stretch reflex in moderate-severe spastic multiple sclerosis patients with implanted pump. ( Nielsen, JF; Sinkjaer, T, 2004)
"To evaluate long-term results of chronic intrathecal Baclofen infusion on the spasticity, on the spasms and to evaluate the side-effects of the intrathecal Baclofen in patients with supraspinal spasticity."5.10Long-term intrathecal Baclofen infusion in supraspinal spasticity of adulthood. ( Bono, G; Casagrande, F; Dario, A; Di Stefano, MG; Grossi, A, 2002)
"Stroke patients with >6 months of intractable spasticity were screened via a randomized, double-blind, placebo-controlled crossover design of either intrathecal normal saline or 50 microgram baclofen."5.09Intrathecal baclofen for spastic hypertonia from stroke. ( Brunner, RC; Guin-Renfroe, S; Hadley, MN; Meythaler, JM, 2001)
" baclofen on spontaneous and evoked (allodynia) dysesthetic pain suggests that a dysfunctional spinal gamma-aminobutyric acidB receptor system, including functional supersensitivity, is associated with the phenomenon of central pain among patients with spinal lesions."5.07Intrathecal baclofen suppresses central pain in patients with spinal lesions. A pilot study. ( D'Luzansky, SC; Herman, RM; Ippolito, R, 1992)
" He developed acute kidney injury at hospital secondary to vancomycin use, and mental status declined."5.05Encephalopathy of Unknown Origin in a Baclofen Patient: Case Report and Review of the Literature. ( Abraham, M; Behmer Hansen, R; Gold, J; Lad, M; Mammis, A; Zhao, K, 2020)
"25 patients with multiple sclerosis (MS) and other spastic disorders, 33 MS patients and 10 control patients with MS were given clonazepam, baclofen or placebo over a period of 5 days to 20 weeks."5.04Clonazepam, baclofen and placebo in the treatment of spasticity. ( Cendrowski, W; Sobczyk, W, 1977)
"Spasms in patients with generalized tetanus can be suppressed by a spinal intrathecal infusion of baclofen."4.79Intrathecal baclofen in tetanus: four cases and a review of reported cases. ( Dressnandt, J; Klingelhöfer, J; Konstanzer, A; Pfab, R; Weinzierl, FX, 1997)
"A retrospective chart review was performed of patients with cerebral palsy undergoing single event, multilevel lower extremity surgery at a single institution who received epidural analgesia with or without continuous baclofen infusion."3.81Epidural Baclofen for the Management of Postoperative Pain in Children With Cerebral Palsy. ( Halanski, MA; Montero, RJ; Nemeth, BA; Noonan, KJ, 2015)
" All our patients underwent continuous infusion of midazolam, in association with pimozide and trihexyphenidyl, which led to complete resolution of muscular spasms in two patients."3.78Management of status dystonicus in children. Cases report and review. ( Balestri, P; Grosso, S; Messina, M; Sacchini, M; Verrotti, A, 2012)
"We report on the case of a patient suffering from Friedreich's ataxia (FA) with very painful and disabling spasms that were improved markedly by intrathecal baclofen infusion."3.73Intrathecal baclofen in the treatment of painful, disabling spasms in Friedreich's ataxia. ( Ben Smail, D; Bussel, B; Denys, P; Jacq, C, 2005)
"Intrathecal baclofen (ITB) is used for unresponsiveness to other treatment for patients with stiff-person syndrome (SPS)."3.72Intrathecal baclofen for stiff-person syndrome: life-threatening intermittent catheter leakage. ( Bardutzky, J; Meinck, HM; Schwab, S; Tronnier, V, 2003)
"To measure the effect of baclofen on the transmission in different spinal pathways to soleus motoneurones in spastic multiple sclerosis patients."3.70The effect of baclofen on the transmission in spinal pathways in spastic multiple sclerosis patients. ( Crone, C; Krarup, C; Nielsen, J; Orsnes, G; Petersen, N, 2000)
"In this case study we describe a dual approach to the palliation of difficult muscle spasms using intrathecal baclofen via a fully implanted system, together with the homeopathic approach to symptom control."3.70Intrathecal baclofen and homeopathy for the treatment of painful muscle spasms associated with malignant spinal cord compression. ( Hicks, F; Thompson, E, 1998)
"A total of 66 consecutive patients with severe spasticity of spinal cord origin were screened with intrathecal baclofen, and all but two responded with a two-point decrease in their Ashworth spasticity scale and/or spasm scale score."3.68Intrathecal baclofen for spasticity of spinal origin: seven years of experience. ( Penn, RD, 1992)
"This study reports the use of intrathecal baclofen in two ventilator-dependent children with severe spasms secondary to spinal-cord injury."3.68Continuous intrathecal baclofen treatment of severe spasms in two children with spinal-cord injury. ( Armstrong, RW; Cochrane, D; Farrell, K; Kube, S; Norman, MG; Steinbok, P, 1992)
"A 58-year-old woman with long-standing hemifacial spasm experienced dramatic relief of symptomatology while receiving baclofen (Lioresal) in a daily dosage of 37."3.67Baclofen in hemifacial spasm. ( Sandyk, R, 1984)
"Six patients with idiopathic hemifacial spasm refractory to the usually employed medications were successfully treated with baclofen."3.67Baclofen in hemifacial spasm. ( Gillman, MA; Sandyk, R, 1987)
"This report summarizes experience with baclofen (Lioresal) in the management of spasticity and muscle spasms in 113 patients treated for up to six years."3.65Bacloffen (Lioresal) in the long-term management of spasticity. ( Jones, RF; Lance, JW, 1976)
"This procedure is recommended for spasticity of spinal origin refractory to physiotherapy and oral medication."2.66Intrathecal baclofen for long-term treatment of spasticity: a multi-centre study. ( Gardner, BP; Gybels, J; Jamous, A; Linderoth, B; Meyerson, BA; Ochs, G; Struppler, A; Teddy, P; Weinmann, P, 1989)
"The medicinal treatment of spasticity includes use of oral treatments (baclofène and tizanidine), botulinum toxin, intrathecal baclofène and local application of alcohol or phenol."2.48[Pharmacological treatment of spasticity in multiple sclerosis]. ( Heinzlef, O; Monteil-Roch, I, 2012)
"The current strategies involved in treating tetanus are discussed."2.43Tetanus in a subcutaneous drug abuser: ineffectiveness of intrathecal baclofen. ( Bellamy, MC; Thomas, RM, 2006)
"It is characterized by muscle spasms triggered by startle, voluntary movement, or tactile or emotional stimuli, occurring predominantly in the axial musculature."1.37Stiff person syndrome and pregnancy. ( Blaskiewicz, R; Goldkamp, J; Myles, T, 2011)
" The aim of our study was to evaluate how dosage level improves the symptoms of spasticity."1.37[Adequate dose of intrathecal baclofen therapy for spasticity]. ( Hirabayashi, H; Motoyama, Y; Nakase, H; Nishimura, F; Wajima, D, 2011)
"Baclofen per se has the potential of lowering blood pressure."1.35Intrathecal baclofen for autonomic instability due to spinal cord injury. ( Kofler, M; Poustka, K; Saltuari, L, 2009)
"Ten patients with severe spasticity were evaluated according to a standardized protocol in order to be treated by intraspinal baclofen."1.28Intraspinal baclofen in the treatment of severe spasticity and spasms. ( Closa, C; Garcia-Fernandez, L; Guitart, JM; Jodar, R; Muxi, T; Noguer, M; Rubio, E; Sahuquillo, J, 1991)
"Acute encephalopathy and an abnormal electroencephalogram with a periodic sharp wave pattern developed in a 58-year-old woman shortly after she received a few doses of baclofen."1.27Periodic sharp waves in baclofen-induced encephalopathy. ( Benarroch, EE; Hormes, JT; Klass, DW; Rodriguez, M, 1988)
"A female patient had permanent axial muscular rigidity similar to the "stiff-man syndrome", together with axial myoclonus triggered by stretch reflexes and by supramaximal stimulation of the supraorbital nerve."1.26Jerking stiff-man syndrome. ( Alberca, R; Chaparro, J; Romero, M, 1982)
"Spasms are increased by Chlorimipramine which may by used as a provocative test in uncertain cases."1.26[The stiff-man syndrome. A case report with regard to clinical, electromyographical and pharmacological signs (author's transl)]. ( Heckl, R; Stöhr, M, 1977)
"In mild spasticity stretch reflexes appear to be suppressed by voluntary effort whereas in severe spasticity they are enhanced."1.26C0-contraction and stretch reflexes in spasticity during treatment with baclofen. ( McLellan, DL, 1977)

Research

Studies (68)

TimeframeStudies, this research(%)All Research%
pre-199026 (38.24)18.7374
1990's14 (20.59)18.2507
2000's15 (22.06)29.6817
2010's10 (14.71)24.3611
2020's3 (4.41)2.80

Authors

AuthorsStudies
Dietz, N1
Wagers, S1
Harkema, SJ1
D'Amico, JM1
Dalakas, MC1
Gold, J1
Zhao, K1
Abraham, M1
Behmer Hansen, R1
Lad, M1
Mammis, A1
Platt, L1
Deboer, SR1
Shenderov, K1
Probasco, JC1
Guterman, EL1
Manesh, R1
Sperati, CJ1
Wallace, E1
Twomey, M1
Victory, R1
O'Reilly, M1
Morota, N1
Kubota, M1
Nemoto, A2
Katayama, Y1
Smadja, J1
Paradis, M1
Nemeth, BA1
Montero, RJ1
Halanski, MA1
Noonan, KJ1
Taira, T2
Hori, T1
Kofler, M1
Poustka, K1
Saltuari, L1
Wajima, D1
Hirabayashi, H1
Nishimura, F1
Motoyama, Y1
Nakase, H1
Goldkamp, J1
Blaskiewicz, R1
Myles, T1
Grosso, S1
Verrotti, A1
Messina, M1
Sacchini, M1
Balestri, P1
Heinzlef, O1
Monteil-Roch, I1
Nyhus, AM1
Bardutzky, J1
Tronnier, V1
Schwab, S1
Meinck, HM1
Nielsen, JF1
Sinkjaer, T1
Ben Smail, D1
Jacq, C1
Denys, P1
Bussel, B1
Hornby, TG1
Kahn, JH1
Wu, M1
Schmit, BD1
Guglani, L1
Lodha, R1
Thomas, RM1
Bellamy, MC1
Sakata, K1
Sandyk, R4
Ortiz, A1
Gillman, MA3
Kirkland, LR1
DeLisa, JA1
Little, J1
Alberca, R1
Romero, M1
Chaparro, J1
Whelan, JL1
Larmande, P1
Bedat, A1
Delplace, MP1
Brodkey, JA1
Feler, CA1
Meythaler, JM2
DeVivo, MJ1
Hadley, M1
Dressnandt, J1
Konstanzer, A1
Weinzierl, FX1
Pfab, R1
Klingelhöfer, J1
Dalvi, A1
Fahn, S1
Ford, B1
Thompson, E1
Hicks, F1
Sampathkumar, P1
Scanlon, PD1
Plevak, DJ1
Taricco, M1
Adone, R1
Pagliacci, C1
Telaro, E1
Orsnes, G1
Crone, C1
Krarup, C1
Petersen, N1
Nielsen, J1
François, B1
Vacher, P1
Roustan, J1
Salle, JY1
Vidal, J1
Moreau, JJ1
Vignon, P1
Guin-Renfroe, S1
Brunner, RC1
Hadley, MN1
Dario, A1
Di Stefano, MG1
Grossi, A1
Casagrande, F1
Bono, G1
Burke, DJ1
Cendrowski, W1
Sobczyk, W1
Roitman, I1
Anghinah, A1
Duncan, GW1
Shahani, BT1
Young, RR1
Roussan, MS1
Abramson, AS1
Levine, SA1
Feibel, A1
Jones, RF1
Lance, JW1
Stöhr, M1
Heckl, R1
McLellan, DL1
Goldblatt, D1
Basmajian, JV1
Calne, DB1
Hedley, DW1
Maroun, JA1
Espir, ML1
Kroin, JS1
Herman, RM1
D'Luzansky, SC1
Ippolito, R1
Penn, RD1
Armstrong, RW2
Steinbok, P1
Farrell, K1
Cochrane, D1
Norman, MG1
Kube, S1
Sahuquillo, J1
Muxi, T1
Noguer, M1
Jodar, R1
Closa, C1
Rubio, E1
Garcia-Fernandez, L1
Guitart, JM1
Ochs, G1
Struppler, A1
Meyerson, BA1
Linderoth, B1
Gybels, J1
Gardner, BP1
Teddy, P1
Jamous, A1
Weinmann, P1
Hormes, JT1
Benarroch, EE1
Rodriguez, M1
Klass, DW1
Pauker, SL1
Brown, R1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Use of Penile Vibratory Stimulation to Decrease Spasticity Following Spinal Cord Injury[NCT00223873]30 participants Interventional2002-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

12 reviews available for baclofen and Spasm

ArticleYear
Intrathecal and Oral Baclofen Use in Adults With Spinal Cord Injury: A Systematic Review of Efficacy in Spasticity Reduction, Functional Changes, Dosing, and Adverse Events.
    Archives of physical medicine and rehabilitation, 2023, Volume: 104, Issue:1

    Topics: Activities of Daily Living; Adult; Baclofen; Humans; Injections, Spinal; Muscle Relaxants, Central;

2023
Therapies in Stiff-Person Syndrome: Advances and Future Prospects Based on Disease Pathophysiology.
    Neurology(R) neuroimmunology & neuroinflammation, 2023, Volume: 10, Issue:3

    Topics: Aged; Autoantibodies; Autoimmunity; Baclofen; Child; Female; Humans; Spasm; Stiff-Person Syndrome

2023
Encephalopathy of Unknown Origin in a Baclofen Patient: Case Report and Review of the Literature.
    World neurosurgery, 2020, Volume: 136

    Topics: Acute Kidney Injury; Adult; Anti-Bacterial Agents; Baclofen; Brain Diseases; Electroencephalography;

2020
[Intrathecal baclofen treatment for spasticity in childhood . initial report of long-term follow up in Japan].
    No to hattatsu = Brain and development, 2014, Volume: 46, Issue:3

    Topics: Adolescent; Baclofen; Child; Child, Preschool; Follow-Up Studies; Humans; Infant; Injections, Spinal

2014
[Intrathecal baclofen therapy].
    No shinkei geka. Neurological surgery, 2008, Volume: 36, Issue:7

    Topics: Baclofen; Humans; Infusion Pumps, Implantable; Injections, Spinal; Muscle Relaxants, Central; Spasm

2008
[Pharmacological treatment of spasticity in multiple sclerosis].
    Revue neurologique, 2012, Volume: 168 Suppl 3

    Topics: Algorithms; Amines; Baclofen; Botulinum Toxins, Type A; Clonidine; Cyclohexanecarboxylic Acids; Dant

2012
Tetanus in a subcutaneous drug abuser: ineffectiveness of intrathecal baclofen.
    Anaesthesia and intensive care, 2006, Volume: 34, Issue:6

    Topics: Adult; Baclofen; Clostridium tetani; Drug Administration Routes; Female; Heroin Dependence; Humans;

2006
[New treatment for spasticity--intrathecal baclofen therapy].
    Nihon rinsho. Japanese journal of clinical medicine, 2008, Volume: 66, Issue:4

    Topics: Baclofen; Humans; Infusion Pumps, Implantable; Injections, Spinal; Muscle Relaxants, Central; Patien

2008
Intrathecal baclofen in tetanus: four cases and a review of reported cases.
    Intensive care medicine, 1997, Volume: 23, Issue:8

    Topics: Adult; Aged; Antidotes; Baclofen; Female; Flumazenil; GABA Agonists; Humans; Injections, Spinal; Mal

1997
Pharmacological interventions for spasticity following spinal cord injury.
    The Cochrane database of systematic reviews, 2000, Issue:2

    Topics: Baclofen; Clonidine; Dantrolene; Humans; Muscle Relaxants, Central; Parasympatholytics; Spasm; Spina

2000
Drug treatment of spasticity and rigidity.
    Modern trends in neurology, 1975, Volume: 6

    Topics: Amantadine; Baclofen; Diazepam; Humans; Levodopa; Mephenesin; Muscle Rigidity; Parasympatholytics; P

1975
Intrathecal drug administration. Present use and future trends.
    Clinical pharmacokinetics, 1992, Volume: 22, Issue:5

    Topics: Analgesics; Baclofen; Brain Diseases; Humans; Injections, Spinal; Neoplasms; Palliative Care; Spasm;

1992

Trials

13 trials available for baclofen and Spasm

ArticleYear
Guided intrathecal baclofen administration by using soleus stretch reflex in moderate-severe spastic multiple sclerosis patients with implanted pump.
    Multiple sclerosis (Houndmills, Basingstoke, England), 2004, Volume: 10, Issue:5

    Topics: Adult; Aged; Baclofen; Female; Humans; Infusion Pumps, Implantable; Injections, Spinal; Male; Middle

2004
Temporal facilitation of spastic stretch reflexes following human spinal cord injury.
    The Journal of physiology, 2006, Mar-15, Volume: 571, Issue:Pt 3

    Topics: Adult; Ankle Joint; Baclofen; Electromyography; Female; Humans; Male; Middle Aged; Motor Neurons; Mu

2006
Prospective study on the use of bolus intrathecal baclofen for spastic hypertonia due to acquired brain injury.
    Archives of physical medicine and rehabilitation, 1996, Volume: 77, Issue:5

    Topics: Adult; Baclofen; Brain Injuries; Cross-Over Studies; Double-Blind Method; Female; Humans; Injections

1996
Intrathecal baclofen for spastic hypertonia from stroke.
    Stroke, 2001, Volume: 32, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Baclofen; Cross-Over Studies; Dose-Response Relationship

2001
Long-term intrathecal Baclofen infusion in supraspinal spasticity of adulthood.
    Acta neurologica Scandinavica, 2002, Volume: 105, Issue:2

    Topics: Adolescent; Adult; Baclofen; Brain Injuries; Female; Glasgow Outcome Scale; Humans; Hypoxia, Brain;

2002
Clonazepam, baclofen and placebo in the treatment of spasticity.
    European neurology, 1977, Volume: 16, Issue:1-6

    Topics: Adolescent; Adult; Aged; Aminobutyrates; Baclofen; Benzodiazepinones; Clinical Trials as Topic; Clon

1977
An evaluation of baclofen treatment for certain symptoms in patients with spinal cord lesions. A double-blind, cross-over study.
    Neurology, 1976, Volume: 26, Issue:5

    Topics: Adult; Aminobutyrates; Baclofen; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Male; Mo

1976
Pharmacological rebound: a tool in the evaluation of antispasticity drugs.
    Archives of physical medicine and rehabilitation, 1976, Volume: 57, Issue:11

    Topics: Adult; Aminobutyrates; Baclofen; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Male; Mi

1976
Lioresal (baclofen) treatment of spasticity in multiple sclerosis.
    American journal of physical medicine, 1975, Volume: 54, Issue:4

    Topics: Adult; Aminobutyrates; Baclofen; Clinical Trials as Topic; Humans; Middle Aged; Multiple Sclerosis;

1975
Evaluation of baclofen (Lioresal) for spasticity in multiple sclerosis.
    Postgraduate medical journal, 1975, Volume: 51, Issue:599

    Topics: Adult; Aged; Aminobutyrates; Baclofen; Clinical Trials as Topic; Female; Humans; Male; Middle Aged;

1975
Intrathecal drug administration. Present use and future trends.
    Clinical pharmacokinetics, 1992, Volume: 22, Issue:5

    Topics: Analgesics; Baclofen; Brain Diseases; Humans; Injections, Spinal; Neoplasms; Palliative Care; Spasm;

1992
Intrathecal baclofen suppresses central pain in patients with spinal lesions. A pilot study.
    The Clinical journal of pain, 1992, Volume: 8, Issue:4

    Topics: Adult; Baclofen; Double-Blind Method; Female; Humans; Injections, Spinal; Male; Middle Aged; Pain; R

1992
Intrathecal baclofen for long-term treatment of spasticity: a multi-centre study.
    Journal of neurology, neurosurgery, and psychiatry, 1989, Volume: 52, Issue:8

    Topics: Adult; Baclofen; Catheters, Indwelling; Clinical Trials as Topic; Electromyography; Female; Follow-U

1989

Other Studies

44 other studies available for baclofen and Spasm

ArticleYear
Egad!
    Journal of hospital medicine, 2019, Volume: 14, Issue:3

    Topics: Aged; Baclofen; Colchicine; Diagnosis, Differential; Female; Gout; Hallux; Hospitalization; Humans;

2019
Intravesical baclofen, bupivacaine, and oxycodone for the relief of bladder spasm.
    Journal of palliative care, 2013,Spring, Volume: 29, Issue:1

    Topics: Administration, Intravesical; Aged; Analgesics, Opioid; Anesthetics, Local; Baclofen; Bupivacaine; D

2013
[Baclofen: Innovative treatment or French controversy?].
    La Revue de medecine interne, 2015, Volume: 36, Issue:1

    Topics: Alcoholism; Baclofen; Behavior; Dissent and Disputes; Drug Repositioning; France; History, 21st Cent

2015
Epidural Baclofen for the Management of Postoperative Pain in Children With Cerebral Palsy.
    Journal of pediatric orthopedics, 2015, Volume: 35, Issue:6

    Topics: Adolescent; Analgesia, Epidural; Baclofen; Cerebral Palsy; Child; Child, Preschool; Female; Humans;

2015
Intrathecal baclofen for autonomic instability due to spinal cord injury.
    Autonomic neuroscience : basic & clinical, 2009, Mar-12, Volume: 146, Issue:1-2

    Topics: Abdominal Wall; Antihypertensive Agents; Autonomic Dysreflexia; Baclofen; Benzimidazoles; Biphenyl C

2009
[Adequate dose of intrathecal baclofen therapy for spasticity].
    No shinkei geka. Neurological surgery, 2011, Volume: 39, Issue:4

    Topics: Adolescent; Adult; Aged; Baclofen; Female; GABA-B Receptor Agonists; Humans; Infusion Pumps; Injecti

2011
Stiff person syndrome and pregnancy.
    Obstetrics and gynecology, 2011, Volume: 118, Issue:2 Pt 2

    Topics: Adult; Amines; Baclofen; Cesarean Section; Cyclohexanecarboxylic Acids; Diazepam; Female; Gabapentin

2011
[Intrathecal baclofen therapy].
    Rinsho shinkeigaku = Clinical neurology, 2010, Volume: 50, Issue:11

    Topics: Baclofen; Central Nervous System Diseases; GABA-B Receptor Agonists; Humans; Infusion Pumps, Implant

2010
Management of status dystonicus in children. Cases report and review.
    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2012, Volume: 16, Issue:4

    Topics: Adolescent; Anti-Dyskinesia Agents; Baclofen; Brain; Case Management; Child; Cysts; Dystonia; Electr

2012
[With a computer in the stomach].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2002, Aug-30, Volume: 122, Issue:20

    Topics: Baclofen; Computers; Female; Humans; Infusion Pumps, Implantable; Muscle Relaxants, Central; Spasm

2002
Intrathecal baclofen for stiff-person syndrome: life-threatening intermittent catheter leakage.
    Neurology, 2003, Jun-24, Volume: 60, Issue:12

    Topics: Acute Disease; Adult; Baclofen; Catheterization; Equipment Failure; Humans; Hypertension; Infusion P

2003
Intrathecal baclofen in the treatment of painful, disabling spasms in Friedreich's ataxia.
    Movement disorders : official journal of the Movement Disorder Society, 2005, Volume: 20, Issue:6

    Topics: Adult; Baclofen; Electromyography; Friedreich Ataxia; Humans; Male; Muscle Relaxants, Central; Pain;

2005
Enteral baclofen in the management of tetanus-related spasms: case report and review of literature.
    Journal of tropical pediatrics, 2007, Volume: 53, Issue:2

    Topics: Baclofen; Child, Preschool; Humans; Male; Muscle Relaxants, Central; Spasm; Tetanus

2007
Baclofen in hemifacial spasm.
    European neurology, 1984, Volume: 23, Issue:3

    Topics: Baclofen; Facial Muscles; Female; Humans; Middle Aged; Muscle Contraction; Spasm

1984
Neuropharmacological profile of Meige's disease: overview and a case report.
    Clinical neuropharmacology, 1983, Volume: 6, Issue:4

    Topics: Aged; Baclofen; Benztropine; Clonazepam; Doxepin; Drug Therapy, Combination; Dystonia; Facial Muscle

1983
Hemifacial spasm--successful treatment with baclofen.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1984, Mar-31, Volume: 65, Issue:13

    Topics: Baclofen; Facial Muscles; Female; Humans; Middle Aged; Spasm

1984
Baclofen dosage: a suggestion.
    Archives of physical medicine and rehabilitation, 1984, Volume: 65, Issue:4

    Topics: Baclofen; Humans; Male; Paraplegia; Spasm

1984
Drugs to relieve spasticity.
    Drug and therapeutics bulletin, 1983, Jan-14, Volume: 21, Issue:1

    Topics: Baclofen; Dantrolene; Diazepam; Humans; Parasympatholytics; Spasm

1983
[Drug knowledge: baclofen (Lioresal)].
    L' Infirmiere canadienne, 1982, Volume: 24, Issue:10

    Topics: Baclofen; Humans; Spasm

1982
Managing spasticity.
    American family physician, 1982, Volume: 26, Issue:3

    Topics: Adult; Baclofen; Child, Preschool; Cold Temperature; Dantrolene; Diazepam; Female; Humans; Muscle Sp

1982
Jerking stiff-man syndrome.
    Journal of neurology, neurosurgery, and psychiatry, 1982, Volume: 45, Issue:12

    Topics: Adult; Baclofen; Diazepam; Female; Humans; Muscle Rigidity; Myoclonus; Spasm

1982
Baclofen in treatment of the 'stiff-man' syndrome.
    Archives of neurology, 1980, Volume: 37, Issue:9

    Topics: Adult; Baclofen; Diazepam; Drug Therapy, Combination; Humans; Male; Muscle Rigidity; Spasm

1980
[Cure of oculomotor paralysis with a muscle relaxant (Baclofen)].
    Journal francais d'ophtalmologie, 1994, Volume: 17, Issue:1

    Topics: Adult; Baclofen; Female; Humans; Oculomotor Muscles; Ophthalmoplegia; Spasm

1994
Hypotension following a trial intrathecal dose of baclofen.
    Journal of the Tennessee Medical Association, 1993, Volume: 86, Issue:7

    Topics: Adult; Baclofen; Humans; Hypotension; Injections, Spinal; Male; Morphine; Spasm

1993
Intrathecal baclofen in the treatment of dystonic storm.
    Movement disorders : official journal of the Movement Disorder Society, 1998, Volume: 13, Issue:3

    Topics: Acute Disease; Adolescent; Baclofen; Dose-Response Relationship, Drug; Drug Administration Schedule;

1998
Intrathecal baclofen and homeopathy for the treatment of painful muscle spasms associated with malignant spinal cord compression.
    Palliative medicine, 1998, Volume: 12, Issue:2

    Topics: Aged; Baclofen; Holistic Health; Homeopathy; Humans; Injections, Spinal; Male; Muscle Relaxants, Cen

1998
Baclofen withdrawal presenting as multiorgan system failure.
    Anesthesia and analgesia, 1998, Volume: 87, Issue:3

    Topics: Adult; Baclofen; Humans; Male; Multiple Organ Failure; Muscle Relaxants, Central; Muscle Spasticity;

1998
[Current data on bipolar disorders, epilepsy and spasticity. 4. Neuro-Forum, Dresden].
    Fortschritte der Neurologie-Psychiatrie, 1999, Volume: 67, Issue:5 Suppl Ak

    Topics: Baclofen; Bipolar Disorder; Clonidine; Epilepsy; Female; Humans; Male; Muscle Relaxants, Central; Mu

1999
The effect of baclofen on the transmission in spinal pathways in spastic multiple sclerosis patients.
    Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2000, Volume: 111, Issue:8

    Topics: Administration, Oral; Adult; Baclofen; Electric Stimulation; Electromyography; Female; H-Reflex; Hum

2000
Intrathecal baclofen after traumatic brain injury: early treatment using a new technique to prevent spasticity.
    The Journal of trauma, 2001, Volume: 50, Issue:1

    Topics: Adult; Autonomic Nervous System Diseases; Baclofen; Brain Injuries; Child; Female; GABA Agonists; Hu

2001
An approach to the treatment of spasticity.
    Drugs, 1975, Volume: 10, Issue:2

    Topics: Adrenergic alpha-Antagonists; Baclofen; Brain Diseases; Dantrolene; Diazepam; Humans; Mephenesin; Mu

1975
[Clinico-quatitative evaluation of the action of Ciba 34.647-Ba on spasticity].
    Arquivos de neuro-psiquiatria, 1977, Volume: 35, Issue:4

    Topics: Adult; Aged; Aminobutyrates; Baclofen; Drug Evaluation; Female; Humans; Male; Middle Aged; Spasm; Sp

1977
Bacloffen (Lioresal) in the long-term management of spasticity.
    The Medical journal of Australia, 1976, May-01, Volume: 1, Issue:18

    Topics: Adolescent; Adult; Aged; Aminobutyrates; Baclofen; Cerebral Palsy; Child; Female; Humans; Long-Term

1976
[The stiff-man syndrome. A case report with regard to clinical, electromyographical and pharmacological signs (author's transl)].
    Archiv fur Psychiatrie und Nervenkrankheiten, 1977, Feb-23, Volume: 223, Issue:2

    Topics: Aged; Baclofen; Clomipramine; Clonazepam; Female; Humans; Muscle Rigidity; Muscles; Reaction Time; S

1977
C0-contraction and stretch reflexes in spasticity during treatment with baclofen.
    Journal of neurology, neurosurgery, and psychiatry, 1977, Volume: 40, Issue:1

    Topics: Adolescent; Adult; Aminobutyrates; Baclofen; Electromyography; Female; Humans; Male; Middle Aged; Mo

1977
Treatment of amyotrophic lateral sclerosis.
    Advances in neurology, 1977, Volume: 17

    Topics: Aging; Amitriptyline; Amyotrophic Lateral Sclerosis; Baclofen; Braces; Dantrolene; Deglutition Disor

1977
Intrathecal baclofen for spasticity of spinal origin: seven years of experience.
    Journal of neurosurgery, 1992, Volume: 77, Issue:2

    Topics: Adolescent; Adult; Aged; Baclofen; Catheterization; Child; Equipment Failure; Female; Humans; Infusi

1992
Continuous intrathecal baclofen treatment of severe spasms in two children with spinal-cord injury.
    Developmental medicine and child neurology, 1992, Volume: 34, Issue:8

    Topics: Adolescent; Baclofen; Catheters, Indwelling; Child; Child, Preschool; Female; Humans; Infusion Pumps

1992
Intrathecal baclofen and spasticity: what do we know and what do we need to know?
    Developmental medicine and child neurology, 1992, Volume: 34, Issue:8

    Topics: Baclofen; Child; Humans; Infusion Pumps, Implantable; Injections, Spinal; Microcomputers; Software;

1992
Intraspinal baclofen in the treatment of severe spasticity and spasms.
    Acta neurochirurgica, 1991, Volume: 110, Issue:3-4

    Topics: Adolescent; Adult; Aged; Baclofen; Child; Dose-Response Relationship, Drug; Electromyography; Female

1991
Periodic sharp waves in baclofen-induced encephalopathy.
    Archives of neurology, 1988, Volume: 45, Issue:7

    Topics: Baclofen; Brain Diseases; Electroencephalography; Female; Humans; Middle Aged; Muscular Diseases; Pa

1988
Baclofen in hemifacial spasm.
    The International journal of neuroscience, 1987, Volume: 33, Issue:3-4

    Topics: Adult; Baclofen; Facial Muscles; Female; Humans; Male; Memory Disorders; Middle Aged; Piracetam; Spa

1987
Baclofen-induced catatonia.
    Journal of clinical psychopharmacology, 1986, Volume: 6, Issue:6

    Topics: Baclofen; Catatonia; Female; Humans; Leg; Middle Aged; Spasm

1986
Baclofen-induced memory impairment.
    Clinical neuropharmacology, 1985, Volume: 8, Issue:3

    Topics: Adult; Baclofen; Female; Humans; Memory, Short-Term; Middle Aged; Multiple Sclerosis; Spasm; Trigemi

1985