Page last updated: 2024-10-23

baclofen and Smoking Cessation

baclofen has been researched along with Smoking Cessation in 5 studies

Smoking Cessation: Discontinuing the habit of SMOKING.

Research Excerpts

ExcerptRelevanceReference
" The ability of the GABA B agonist, baclofen to ameliorate nicotine and drug motivated behavior is established within the animal literature, however its potential to do so in humans is understudied, particularly with respect to its possible utility as a smoking cessation agent."5.14The GABA B agonist baclofen reduces cigarette consumption in a preliminary double-blind placebo-controlled smoking reduction study. ( Childress, AR; Franklin, TR; Harper, D; Jens, W; Kampman, K; Kildea-McCrea, S; Lynch, KG; O'Brien, CP, 2009)
"Baclofen has been reported in uncontrolled clinical studies to reduce craving for abused drugs and reduce their rewarding effects."2.70Effects of a single dose of baclofen on self-reported subjective effects and tobacco smoking. ( Cousins, MS; de Wit, H; Stamat, HM, 2001)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Franklin, TR2
Harper, D1
Kampman, K1
Kildea-McCrea, S1
Jens, W1
Lynch, KG1
O'Brien, CP2
Childress, AR2
Varani, AP1
Moutinho, LM1
Calvo, M1
Balerio, GN1
Shin, J1
Jagannathan, K1
Suh, JJ1
Detre, JA1
Shoptaw, S1
Belin, TR1
Cousins, MS1
Stamat, HM1
de Wit, H1

Reviews

1 review available for baclofen and Smoking Cessation

ArticleYear
Markov transition models for binary repeated measures with ignorable and nonignorable missing values.
    Statistical methods in medical research, 2007, Volume: 16, Issue:4

    Topics: Baclofen; Cocaine-Related Disorders; GABA Agonists; Humans; Longitudinal Studies; Markov Chains; Mod

2007

Trials

2 trials available for baclofen and Smoking Cessation

ArticleYear
The GABA B agonist baclofen reduces cigarette consumption in a preliminary double-blind placebo-controlled smoking reduction study.
    Drug and alcohol dependence, 2009, Jul-01, Volume: 103, Issue:1-2

    Topics: Adult; Baclofen; Behavior Therapy; Double-Blind Method; Educational Status; Female; GABA Antagonists

2009
Effects of a single dose of baclofen on self-reported subjective effects and tobacco smoking.
    Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2001, Volume: 3, Issue:2

    Topics: Acute Disease; Adult; Affect; Baclofen; Dose-Response Relationship, Drug; Double-Blind Method; Femal

2001

Other Studies

2 other studies available for baclofen and Smoking Cessation

ArticleYear
Ability of baclofen to prevent somatic manifestations and neurochemical changes during nicotine withdrawal.
    Drug and alcohol dependence, 2011, Dec-01, Volume: 119, Issue:1-2

    Topics: Animals; Baclofen; Behavior, Animal; Disease Models, Animal; Drug Evaluation, Preclinical; Male; Mec

2011
Acute baclofen diminishes resting baseline blood flow to limbic structures: a perfusion fMRI study.
    Drug and alcohol dependence, 2012, Sep-01, Volume: 125, Issue:1-2

    Topics: Adolescent; Adult; Baclofen; Cerebral Cortex; Cerebrovascular Circulation; Cluster Analysis; Cross-O

2012