Page last updated: 2024-10-23

baclofen and Serotonin Syndrome

baclofen has been researched along with Serotonin Syndrome in 2 studies

Serotonin Syndrome: An adverse drug interaction characterized by altered mental status, autonomic dysfunction, and neuromuscular abnormalities. It is most frequently caused by use of both serotonin reuptake inhibitors and monoamine oxidase inhibitors, leading to excess serotonin availability in the CNS at the serotonin 1A receptor.

Research Excerpts

ExcerptRelevanceReference
"Intrathecal baclofen (ITB) is increasingly being used to reduce spasticity among children with cerebral palsy, dystonia, and spinal cord injuries."7.74Intrathecal baclofen withdrawal resembling serotonin syndrome in an adolescent boy with cerebral palsy. ( Eiland, LS; Salazar, ML, 2008)
" Syndromes include adrenergic "fever," anticholinergic "fever," antidopaminergic "fever," serotonin syndrome, malignant hyperthermia, uncoupling of oxidative phosphorylation, and withdrawal from baclofen."4.86Adverse drug reactions resulting in hyperthermia in the intensive care unit. ( McAllen, KJ; Schwartz, DR, 2010)
"Intrathecal baclofen (ITB) is increasingly being used to reduce spasticity among children with cerebral palsy, dystonia, and spinal cord injuries."3.74Intrathecal baclofen withdrawal resembling serotonin syndrome in an adolescent boy with cerebral palsy. ( Eiland, LS; Salazar, ML, 2008)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Salazar, ML1
Eiland, LS1
McAllen, KJ1
Schwartz, DR1

Reviews

1 review available for baclofen and Serotonin Syndrome

ArticleYear
Adverse drug reactions resulting in hyperthermia in the intensive care unit.
    Critical care medicine, 2010, Volume: 38, Issue:6 Suppl

    Topics: Baclofen; Critical Care; Drug-Related Side Effects and Adverse Reactions; Fever; Humans; Intensive C

2010

Other Studies

1 other study available for baclofen and Serotonin Syndrome

ArticleYear
Intrathecal baclofen withdrawal resembling serotonin syndrome in an adolescent boy with cerebral palsy.
    Pediatric emergency care, 2008, Volume: 24, Issue:10

    Topics: Abdominal Pain; Adolescent; Autonomic Dysreflexia; Baclofen; Cerebral Palsy; Diagnosis, Differential

2008