Page last updated: 2024-10-23

baclofen and Scoliosis

baclofen has been researched along with Scoliosis in 26 studies

Scoliosis: An appreciable lateral deviation in the normally straight vertical line of the spine. (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"Intrathecal baclofen (ITB) is an effective treatment of spasticity in patients with cerebral palsy."9.13The impact of intrathecal baclofen on the natural history of scoliosis in cerebral palsy. ( Cabrera, MN; Frino, J; Lai, LP; Shilt, JS; Smith, BP, 2008)
"Patients with early-onset scoliosis (EOS) and spasticity may receive treatment with an intrathecal baclofen pump."8.12Baclofen Pump Use: Complications After Growth-friendly Instrumentation for Early-onset Scoliosis. ( Erickson, MA; Groves, ML; Hardesty, CK; Marrache, M; Murphy, RF; Sponseller, PD; Thompson, GH; Xu, AL, 2022)
"In patients with cerebral palsy (CP), we determine the impact of intrathecal baclofen pumps (ITBPs) on scoliosis curve progression before posterior spine fusion (PSF) and its effects on surgical outcome."7.96Does an intrathecal baclofen pump impact scoliosis progression and complicate posterior spine fusion in patients with cerebral palsy? ( Halanski, MA; Hetzel, SJ; Lins, LAB; Nechyporenko, AV; Noonan, KJ, 2020)
"OBJECTIVE Many patients undergoing spinal fusion for neuromuscular scoliosis have preexisting neurosurgical implants, including ventricular shunts (VSs) for hydrocephalus and baclofen pumps (BPs) for spastic cerebral palsy."7.88Complication rates for preexisting baclofen pumps and ventricular shunts following scoliosis correction: a preliminary study. ( Bonfield, CM; Chotai, S; Dallas, J; Guidry, BS; Sborov, KD, 2018)
"Compare a group of individuals with cerebral palsy (CP) who had intrathecal baclofen (ITB) pumps to a group of individuals with CP who did not have ITB pumps in order to determine if there was a difference in the prevalence of new-onset neuromuscular scoliosis, an increased rate of progression of preexisting neuromuscular scoliosis, or an increased rate of posterior spine fusion surgery in skeletally immature individuals with CP who had ITB pumps."7.85Does Intrathecal Baclofen Therapy Increase Prevalence and/or Progression of Neuromuscular Scoliosis? ( Krach, LE; Novotny, SA; Walker, KR, 2017)
"To compare scoliosis progression in quadriplegic spastic cerebral palsy with and without intrathecal baclofen (ITB) pumps."7.85Intrathecal baclofen pumps do not accelerate progression of scoliosis in quadriplegic spastic cerebral palsy. ( Ammar, A; Aujla, RK; Grevitt, MP; Nasto, LA; Rushton, PRP; Vloeberghs, MH, 2017)
"To compare patients with operative cerebral palsy with and without an intrathecal baclofen pump (ITB) to determine whether an ITB increases the complexity of scoliosis surgery and/or increases the risk of wound complications."7.81Although inconvenient, baclofen pumps do not complicate scoliosis surgery in patients with cerebral palsy. ( Asghar, J; Bastrom, TP; Bomar, JD; Newton, PO; Samdani, AF; Scannell, BP; Shah, SA; Sponseller, PD; Yaszay, B, 2015)
"In the authors' group of patients there was notable development and progression of scoliosis at a greater than previously reported rate for the same patient population, and also greater than previously reported patients with intrathecal baclofen pumps."7.76Do baclofen pumps influence the development of scoliosis in children? ( Burn, SC; Drake, JM; Zeller, R, 2010)
"Because of the increased number of patients with neuromuscular scoliosis receiving intrathecal baclofen therapy, we report a clinical case of withdrawal."7.74Intrathecal baclofen withdrawal syndrome following posterior spinal fusion for neuromuscular scoliosis: a case report. ( Dolan, L; Fernandes, P; Weinstein, SL, 2008)
"To identify the effect of intrathecal baclofen on the incidence of scoliosis, rate of curve progression, and pelvic obliquity compared with a matched cohort."7.74The risk of progression of scoliosis in cerebral palsy patients after intrathecal baclofen therapy. ( Dabney, KW; Glutting, JW; Miller, F; Presedo, A; Senaran, H; Shah, SA, 2007)
"Medical and radiographic review of 19 consecutive patients with spastic quadriplegia before and after intrathecal baclofen pump insertion with special attention paid to progression of scoliosis."7.74Progression of scoliosis in patients with spastic quadriplegia after the insertion of an intrathecal baclofen pump. ( Ginsburg, GM; Lauder, AJ, 2007)
" Four patients documented progression of the major scoliosis curve after intrathecal baclofen infusion was begun."7.73Potential complications of posterior spine fusion and instrumentation in patients with cerebral palsy treated with intrathecal baclofen infusion. ( Kanev, PM; Segal, LS; Wallach, DM, 2005)
"An ITB pump was inserted to manage spasticity."6.66Severe Neuromuscular Scoliosis Implicated by Dysfunction of Intrathecal Baclofen Pump: Case Report and Review of the Literature. ( Apostolopoulou, K; Panagopoulos, D; Themistocleous, M, 2020)
"Because of severe spasticity, many of these patients undergo intrathecal baclofen pump placement before, during, or after posterior spinal fusion."6.52Scoliosis, spinal fusion, and intrathecal baclofen pump implantation. ( Scannell, B; Yaszay, B, 2015)
"Scoliosis is commonly found in children with cerebral palsy."5.43Intrathecal Baclofen Therapy in a Child With Severe Scoliosis: Report of 2 Cases. ( Ogiwara, H; Sasaki, N, 2016)
"Four children had untreated scoliosis and corrective surgery was being contemplated."5.38Cervical implantation of intrathecal baclofen pump catheter in children with severe scoliosis. ( Ammar, A; Ingale, H; Moussa, A; Muquit, S; Ughratdar, I; Vloeberghs, M, 2012)
"Intrathecal baclofen (ITB) is an effective treatment of spasticity in patients with cerebral palsy."5.13The impact of intrathecal baclofen on the natural history of scoliosis in cerebral palsy. ( Cabrera, MN; Frino, J; Lai, LP; Shilt, JS; Smith, BP, 2008)
"There are 3 surgical procedures that patients with cerebral palsy (CP) undergo that may be considered major procedures: femoral osteotomies combined with pelvic osteotomies, spine fusion, and intrathecal baclofen pump implant for the treatment of spasticity."4.90Major surgical procedures in children with cerebral palsy. ( DiCindio, S; Theroux, MC, 2014)
"In patients with cerebral palsy (CP), we determine the impact of intrathecal baclofen pumps (ITBPs) on scoliosis curve progression before posterior spine fusion (PSF) and its effects on surgical outcome."3.96Does an intrathecal baclofen pump impact scoliosis progression and complicate posterior spine fusion in patients with cerebral palsy? ( Halanski, MA; Hetzel, SJ; Lins, LAB; Nechyporenko, AV; Noonan, KJ, 2020)
"OBJECTIVE Many patients undergoing spinal fusion for neuromuscular scoliosis have preexisting neurosurgical implants, including ventricular shunts (VSs) for hydrocephalus and baclofen pumps (BPs) for spastic cerebral palsy."3.88Complication rates for preexisting baclofen pumps and ventricular shunts following scoliosis correction: a preliminary study. ( Bonfield, CM; Chotai, S; Dallas, J; Guidry, BS; Sborov, KD, 2018)
"Compare a group of individuals with cerebral palsy (CP) who had intrathecal baclofen (ITB) pumps to a group of individuals with CP who did not have ITB pumps in order to determine if there was a difference in the prevalence of new-onset neuromuscular scoliosis, an increased rate of progression of preexisting neuromuscular scoliosis, or an increased rate of posterior spine fusion surgery in skeletally immature individuals with CP who had ITB pumps."3.85Does Intrathecal Baclofen Therapy Increase Prevalence and/or Progression of Neuromuscular Scoliosis? ( Krach, LE; Novotny, SA; Walker, KR, 2017)
"To compare scoliosis progression in quadriplegic spastic cerebral palsy with and without intrathecal baclofen (ITB) pumps."3.85Intrathecal baclofen pumps do not accelerate progression of scoliosis in quadriplegic spastic cerebral palsy. ( Ammar, A; Aujla, RK; Grevitt, MP; Nasto, LA; Rushton, PRP; Vloeberghs, MH, 2017)
"We performed scoliosis correction along with removal of baclofen pump and selective dorsal rhizotomy (SDR), as a single combined procedure."3.83Combined selective dorsal rhizotomy and scoliosis correction procedure in patients with cerebral palsy. ( Ammar, A; Mehdian, H; Moussa, AA; Muquit, S; Nasto, L; Vloeberghs, MH, 2016)
"To compare patients with operative cerebral palsy with and without an intrathecal baclofen pump (ITB) to determine whether an ITB increases the complexity of scoliosis surgery and/or increases the risk of wound complications."3.81Although inconvenient, baclofen pumps do not complicate scoliosis surgery in patients with cerebral palsy. ( Asghar, J; Bastrom, TP; Bomar, JD; Newton, PO; Samdani, AF; Scannell, BP; Shah, SA; Sponseller, PD; Yaszay, B, 2015)
"In the authors' group of patients there was notable development and progression of scoliosis at a greater than previously reported rate for the same patient population, and also greater than previously reported patients with intrathecal baclofen pumps."3.76Do baclofen pumps influence the development of scoliosis in children? ( Burn, SC; Drake, JM; Zeller, R, 2010)
"Because of the increased number of patients with neuromuscular scoliosis receiving intrathecal baclofen therapy, we report a clinical case of withdrawal."3.74Intrathecal baclofen withdrawal syndrome following posterior spinal fusion for neuromuscular scoliosis: a case report. ( Dolan, L; Fernandes, P; Weinstein, SL, 2008)
"To identify the effect of intrathecal baclofen on the incidence of scoliosis, rate of curve progression, and pelvic obliquity compared with a matched cohort."3.74The risk of progression of scoliosis in cerebral palsy patients after intrathecal baclofen therapy. ( Dabney, KW; Glutting, JW; Miller, F; Presedo, A; Senaran, H; Shah, SA, 2007)
"Medical and radiographic review of 19 consecutive patients with spastic quadriplegia before and after intrathecal baclofen pump insertion with special attention paid to progression of scoliosis."3.74Progression of scoliosis in patients with spastic quadriplegia after the insertion of an intrathecal baclofen pump. ( Ginsburg, GM; Lauder, AJ, 2007)
"CP patients treated with continuous intrathecal baclofen (ITB) can develop neuromuscular scoliosis and may require spinal fusion with instrumentation."3.74Outcomes of posterior spinal fusion and instrumentation in patients with continuous intrathecal baclofen infusion pumps. ( Ayyangar, RN; Caird, MS; Drongowski, A; Farley, FA; Garton, H; Hensinger, RN; Palanca, AA, 2008)
" Four patients documented progression of the major scoliosis curve after intrathecal baclofen infusion was begun."3.73Potential complications of posterior spine fusion and instrumentation in patients with cerebral palsy treated with intrathecal baclofen infusion. ( Kanev, PM; Segal, LS; Wallach, DM, 2005)
"An ITB pump was inserted to manage spasticity."2.66Severe Neuromuscular Scoliosis Implicated by Dysfunction of Intrathecal Baclofen Pump: Case Report and Review of the Literature. ( Apostolopoulou, K; Panagopoulos, D; Themistocleous, M, 2020)
"Because of severe spasticity, many of these patients undergo intrathecal baclofen pump placement before, during, or after posterior spinal fusion."2.52Scoliosis, spinal fusion, and intrathecal baclofen pump implantation. ( Scannell, B; Yaszay, B, 2015)
"05), while baclofen dosage increased (p = 0."1.40Intrathecal baclofen therapy in children with severe spasticity: Outcome and complications. ( Altermatt, S; Furrer, C; Meyer-Heim, A; Walter, M, 2014)
"Our experience shows that low cervical catheter insertion for administration of a test dose of intrathecal baclofen and feasible and safe to perform via the method described."1.38Cervical catheter placement for intrathecal baclofen test dose: is it safe? ( Ingale, H; Muquit, S; Ughratdar, I; Vloeberghs, M, 2012)
"Four children had untreated scoliosis and corrective surgery was being contemplated."1.38Cervical implantation of intrathecal baclofen pump catheter in children with severe scoliosis. ( Ammar, A; Ingale, H; Moussa, A; Muquit, S; Ughratdar, I; Vloeberghs, M, 2012)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (30.77)29.6817
2010's14 (53.85)24.3611
2020's4 (15.38)2.80

Authors

AuthorsStudies
Xu, AL1
Marrache, M1
Hardesty, CK1
Groves, ML1
Erickson, MA1
Murphy, RF1
Thompson, GH1
Sponseller, PD2
Panagopoulos, D1
Apostolopoulou, K1
Themistocleous, M1
Lins, LAB1
Nechyporenko, AV1
Halanski, MA1
Hetzel, SJ1
Noonan, KJ1
Oh, DC1
Rakesh, N1
LaGrant, B1
Sein, M1
Walker, KR1
Novotny, SA1
Krach, LE1
Aljuboori, Z1
Archer, J1
Huff, W1
Moreno, A1
Jea, A1
Dallas, J1
Sborov, KD1
Guidry, BS1
Chotai, S1
Bonfield, CM1
Walter, M1
Altermatt, S1
Furrer, C1
Meyer-Heim, A1
Theroux, MC1
DiCindio, S1
Arishima, H1
Kikuta, K1
Scannell, B1
Yaszay, B2
Scannell, BP1
Bomar, JD1
Shah, SA2
Asghar, J1
Samdani, AF1
Bastrom, TP1
Newton, PO1
Muquit, S3
Ammar, A3
Nasto, L1
Moussa, AA1
Mehdian, H1
Vloeberghs, MH2
Rushton, PRP1
Nasto, LA1
Aujla, RK1
Grevitt, MP1
Sasaki, N1
Ogiwara, H1
Shilt, JS1
Lai, LP1
Cabrera, MN1
Frino, J1
Smith, BP1
Fernandes, P1
Dolan, L1
Weinstein, SL1
Burn, SC1
Zeller, R1
Drake, JM1
Ughratdar, I2
Ingale, H2
Vloeberghs, M2
Moussa, A1
Segal, LS1
Wallach, DM1
Kanev, PM1
Ceulemans, B1
van Rhijn, J1
Kenis, S1
Krols, R1
Laridon, A1
Van Havenbergh, T1
Hart, AR1
Tripathi, C1
Rowland, DJ1
Broadley, P1
Mordekar, SR1
Senaran, H1
Presedo, A1
Dabney, KW1
Glutting, JW1
Miller, F1
Ginsburg, GM1
Lauder, AJ1
Caird, MS1
Palanca, AA1
Garton, H1
Hensinger, RN1
Ayyangar, RN1
Drongowski, A1
Farley, FA1

Reviews

3 reviews available for baclofen and Scoliosis

ArticleYear
Severe Neuromuscular Scoliosis Implicated by Dysfunction of Intrathecal Baclofen Pump: Case Report and Review of the Literature.
    World neurosurgery, 2020, Volume: 134

    Topics: Baclofen; Child; Equipment Failure; Female; Humans; Hypoxia, Brain; Infusion Pumps, Implantable; Inj

2020
Major surgical procedures in children with cerebral palsy.
    Anesthesiology clinics, 2014, Volume: 32, Issue:1

    Topics: Anesthetics; Baclofen; Cerebral Palsy; Child; Humans; Injections, Spinal; Kyphosis; Muscle Relaxants

2014
Scoliosis, spinal fusion, and intrathecal baclofen pump implantation.
    Physical medicine and rehabilitation clinics of North America, 2015, Volume: 26, Issue:1

    Topics: Baclofen; Cerebral Palsy; Humans; Infusion Pumps, Implantable; Muscle Relaxants, Central; Muscle Spa

2015

Trials

1 trial available for baclofen and Scoliosis

ArticleYear
The impact of intrathecal baclofen on the natural history of scoliosis in cerebral palsy.
    Journal of pediatric orthopedics, 2008, Volume: 28, Issue:6

    Topics: Adolescent; Baclofen; Case-Control Studies; Cerebral Palsy; Child; Child, Preschool; Disease Progres

2008

Other Studies

22 other studies available for baclofen and Scoliosis

ArticleYear
Baclofen Pump Use: Complications After Growth-friendly Instrumentation for Early-onset Scoliosis.
    Journal of pediatric orthopedics, 2022, Feb-01, Volume: 42, Issue:2

    Topics: Baclofen; Humans; Infusion Pumps, Implantable; Muscle Relaxants, Central; Retrospective Studies; Sco

2022
Does an intrathecal baclofen pump impact scoliosis progression and complicate posterior spine fusion in patients with cerebral palsy?
    Spine deformity, 2020, Volume: 8, Issue:1

    Topics: Adolescent; Adult; Baclofen; Cerebral Palsy; Child; Disease Progression; Female; Humans; Infusion Pu

2020
Advanced Progression of Scoliosis After Intrathecal Baclofen in an Adult With Stiff Person Syndrome: A Case Report.
    A&A practice, 2020, Volume: 14, Issue:6

    Topics: Adult; Baclofen; Child; Humans; Scoliosis; Stiff-Person Syndrome

2020
Does Intrathecal Baclofen Therapy Increase Prevalence and/or Progression of Neuromuscular Scoliosis?
    Spine deformity, 2017, Volume: 5, Issue:6

    Topics: Adolescent; Baclofen; Case-Control Studies; Cerebral Palsy; Chi-Square Distribution; Child; Disease

2017
Placement of baclofen pump catheter through a C1-2 puncture: technical note.
    Journal of neurosurgery. Pediatrics, 2018, Volume: 21, Issue:4

    Topics: Adolescent; Baclofen; Cerebral Palsy; Child; Child, Preschool; Epilepsy; Female; Humans; Infusion Pu

2018
Complication rates for preexisting baclofen pumps and ventricular shunts following scoliosis correction: a preliminary study.
    Journal of neurosurgery. Pediatrics, 2018, Volume: 22, Issue:1

    Topics: Adolescent; Baclofen; Child; Female; Follow-Up Studies; Humans; Infusion Pumps, Implantable; Male; M

2018
Intrathecal baclofen therapy in children with severe spasticity: Outcome and complications.
    Developmental neurorehabilitation, 2014, Volume: 17, Issue:6

    Topics: Adolescent; Baclofen; Brain Diseases; Brain Injuries; Child; Child, Preschool; Female; Follow-Up Stu

2014
Intrathecal baclofen pump implantation in prone position for a cerebral palsy patient with severe scoliosis: a case report.
    Neuromodulation : journal of the International Neuromodulation Society, 2015, Volume: 18, Issue:3

    Topics: Baclofen; Female; Humans; Infusion Pumps, Implantable; Injections, Spinal; Middle Aged; Muscle Relax

2015
Although inconvenient, baclofen pumps do not complicate scoliosis surgery in patients with cerebral palsy.
    Spine, 2015, Apr-15, Volume: 40, Issue:8

    Topics: Adolescent; Baclofen; Blood Loss, Surgical; Catheters, Indwelling; Cerebral Palsy; Child; Cicatrix;

2015
Combined selective dorsal rhizotomy and scoliosis correction procedure in patients with cerebral palsy.
    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2016, Volume: 25, Issue:2

    Topics: Adolescent; Baclofen; Cerebral Palsy; Device Removal; Female; Humans; Infusion Pumps, Implantable; M

2016
Intrathecal baclofen pumps do not accelerate progression of scoliosis in quadriplegic spastic cerebral palsy.
    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2017, Volume: 26, Issue:6

    Topics: Baclofen; Case-Control Studies; Cerebral Palsy; Child; Cohort Studies; Disease Progression; Female;

2017
Intrathecal Baclofen Therapy in a Child With Severe Scoliosis: Report of 2 Cases.
    Neuromodulation : journal of the International Neuromodulation Society, 2016, Volume: 19, Issue:6

    Topics: Adolescent; Animals; Baclofen; Child; Female; Humans; Infusion Pumps, Implantable; Injections, Spina

2016
Intrathecal baclofen withdrawal syndrome following posterior spinal fusion for neuromuscular scoliosis: a case report.
    The Iowa orthopaedic journal, 2008, Volume: 28

    Topics: Administration, Oral; Adolescent; Baclofen; Female; Humans; Infusion Pumps, Implantable; Injections,

2008
Do baclofen pumps influence the development of scoliosis in children?
    Journal of neurosurgery. Pediatrics, 2010, Volume: 5, Issue:2

    Topics: Adolescent; Aging; Baclofen; Cerebral Palsy; Child; Child, Preschool; Disease Progression; Dystonia;

2010
Cervical catheter placement for intrathecal baclofen test dose: is it safe?
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2012, Volume: 28, Issue:6

    Topics: Adolescent; Baclofen; Brain Diseases, Metabolic, Inborn; Catheterization; Catheters, Indwelling; Cer

2012
Cervical implantation of intrathecal baclofen pump catheter in children with severe scoliosis.
    Journal of neurosurgery. Pediatrics, 2012, Volume: 10, Issue:1

    Topics: Adolescent; Baclofen; Catheters, Indwelling; Cervical Vertebrae; Child; Female; Humans; Infusion Pum

2012
Potential complications of posterior spine fusion and instrumentation in patients with cerebral palsy treated with intrathecal baclofen infusion.
    Spine, 2005, Apr-15, Volume: 30, Issue:8

    Topics: Adolescent; Adult; Baclofen; Cerebral Palsy; Drug Delivery Systems; Headache; Humans; Injections, Sp

2005
Opisthotonus and intrathecal treatment with baclofen (ITB) in children.
    European journal of pediatrics, 2008, Volume: 167, Issue:6

    Topics: Adolescent; Adult; Baclofen; Belgium; Child; Child, Preschool; Dystonia; Epilepsy; Female; Follow-Up

2008
'Rapid progression of scoliosis complicating intrathecal baclofen pump insertion'.
    Developmental medicine and child neurology, 2007, Volume: 49, Issue:9

    Topics: Adolescent; Baclofen; Child; Disease Progression; Female; Humans; Infusion Pumps, Implantable; Injec

2007
The risk of progression of scoliosis in cerebral palsy patients after intrathecal baclofen therapy.
    Spine, 2007, Oct-01, Volume: 32, Issue:21

    Topics: Adolescent; Baclofen; Cerebral Palsy; Child; Child, Preschool; Disease Progression; Female; Humans;

2007
Progression of scoliosis in patients with spastic quadriplegia after the insertion of an intrathecal baclofen pump.
    Spine, 2007, Nov-15, Volume: 32, Issue:24

    Topics: Adolescent; Adult; Baclofen; Cerebral Palsy; Child; Child, Preschool; Disease Progression; Female; H

2007
Outcomes of posterior spinal fusion and instrumentation in patients with continuous intrathecal baclofen infusion pumps.
    Spine, 2008, Feb-15, Volume: 33, Issue:4

    Topics: Adolescent; Adult; Baclofen; Cerebral Palsy; Child; Female; Humans; Infusion Pumps, Implantable; Inj

2008