baclofen has been researched along with Reperfusion Injury in 7 studies
Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "These results indicate that activation of GABAA receptors, which include the specific binding subunits for propofol and midazolam, but not pentobarbital, plays a role in the inhibition of neuronal death induced by brain ischemia." | 7.70 | Neuroprotective properties of propofol and midazolam, but not pentobarbital, on neuronal damage induced by forebrain ischemia, based on the GABAA receptors. ( Isshiki, A; Ito, H; Uchino, H; Watanabe, Y, 1999) |
| "These results indicate that activation of GABAA receptors, which include the specific binding subunits for propofol and midazolam, but not pentobarbital, plays a role in the inhibition of neuronal death induced by brain ischemia." | 3.70 | Neuroprotective properties of propofol and midazolam, but not pentobarbital, on neuronal damage induced by forebrain ischemia, based on the GABAA receptors. ( Isshiki, A; Ito, H; Uchino, H; Watanabe, Y, 1999) |
| "TTC staining was used to detect cerebral infarction volume, and the brain water content of rats in each group was determined by wet and dry weight method." | 1.91 | [Effects of Governor Vessel electroacupuncture on chloridion homeostasis in the cortex of rats with limb spasm after cerebral ischemia-reperfusion]. ( Guo, J; Li, JW; Li, RQ; Mei, JJ; Wang, YY; Zhang, JY; Zhang, LH, 2023) |
| "In baclofen/muscimol treated eyes the ERG b-wave went from 426+/-101 microV to 148+/-118 microV (n=6)." | 1.35 | GABA agonists fail to protect the retina from ischemia-reperfusion injury. ( Agnarsson, BA; Eysteinsson, T; Stefánsson, E; Traustason, S, 2009) |
| "In global cerebral ischemia, focal cerebral ischemia and oxygen-glucose deprivation, application of muscimol and baclofen, agonists of GABA(A) receptor and GABA(B) receptor, exerted neuroprotection." | 1.35 | Co-activation of GABA receptors inhibits the JNK3 apoptotic pathway via the disassembly of the GluR6-PSD95-MLK3 signaling module in cerebral ischemic-reperfusion. ( Han, D; Li, C; Wang, W; Yan, JZ; Yu, CZ; Zhang, GY; Zhang, QG; Zong, YY, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, YY | 1 |
| Li, RQ | 1 |
| Li, JW | 1 |
| Mei, JJ | 1 |
| Zhang, LH | 1 |
| Zhang, JY | 1 |
| Guo, J | 1 |
| Traustason, S | 1 |
| Eysteinsson, T | 1 |
| Agnarsson, BA | 1 |
| Stefánsson, E | 1 |
| Kobuchi, S | 2 |
| Shintani, T | 2 |
| Sugiura, T | 1 |
| Tanaka, R | 2 |
| Suzuki, R | 2 |
| Tsutsui, H | 2 |
| Fujii, T | 1 |
| Ohkita, M | 2 |
| Ayajiki, K | 2 |
| Matsumura, Y | 2 |
| Rane, MJ | 1 |
| Gozal, D | 1 |
| Butt, W | 1 |
| Gozal, E | 1 |
| Pierce, WM | 1 |
| Guo, SZ | 1 |
| Wu, R | 1 |
| Goldbart, AD | 1 |
| Thongboonkerd, V | 1 |
| McLeish, KR | 1 |
| Klein, JB | 1 |
| Han, D | 1 |
| Zhang, QG | 1 |
| Li, C | 1 |
| Zong, YY | 1 |
| Yu, CZ | 1 |
| Wang, W | 1 |
| Yan, JZ | 1 |
| Zhang, GY | 1 |
| Ito, H | 1 |
| Watanabe, Y | 1 |
| Isshiki, A | 1 |
| Uchino, H | 1 |
7 other studies available for baclofen and Reperfusion Injury
| Article | Year |
|---|---|
[Effects of Governor Vessel electroacupuncture on chloridion homeostasis in the cortex of rats with limb spasm after cerebral ischemia-reperfusion].
Topics: Animals; Baclofen; Cerebral Cortex; Cerebral Infarction; Electroacupuncture; gamma-Aminobutyric Acid | 2023 |
GABA agonists fail to protect the retina from ischemia-reperfusion injury.
Topics: Animals; Baclofen; Drug Combinations; Drug Evaluation, Preclinical; Electroretinography; Female; GAB | 2009 |
Renoprotective effects of gamma-aminobutyric acid on ischemia/reperfusion-induced renal injury in rats.
Topics: Animals; Baclofen; Benzylamines; GABA Agonists; GABA Antagonists; GABA-B Receptor Antagonists; gamma | 2009 |
Mechanisms underlying the renoprotective effect of GABA against ischemia/reperfusion-induced renal injury in rats.
Topics: Acute Kidney Injury; Animals; Baclofen; Benzylamines; Bicuculline; Blood Urea Nitrogen; GABA Agonist | 2011 |
Gamma-amino butyric acid type B receptors stimulate neutrophil chemotaxis during ischemia-reperfusion.
Topics: Animals; Baclofen; Cells, Cultured; Cerebral Infarction; Chemotaxis, Leukocyte; Humans; Immunoprecip | 2005 |
Co-activation of GABA receptors inhibits the JNK3 apoptotic pathway via the disassembly of the GluR6-PSD95-MLK3 signaling module in cerebral ischemic-reperfusion.
Topics: Animals; Apoptosis; Baclofen; Brain Ischemia; Disks Large Homolog 4 Protein; GABA Agonists; GluK2 Ka | 2008 |
Neuroprotective properties of propofol and midazolam, but not pentobarbital, on neuronal damage induced by forebrain ischemia, based on the GABAA receptors.
Topics: Anesthetics, Intravenous; Animals; Baclofen; Brain Ischemia; Dose-Response Relationship, Drug; GABA | 1999 |