baclofen has been researched along with Renal Insufficiency, Chronic in 7 studies
Renal Insufficiency, Chronic: Conditions in which the KIDNEYS perform below the normal level for more than three months. Chronic kidney insufficiency is classified by five stages according to the decline in GLOMERULAR FILTRATION RATE and the degree of kidney damage (as measured by the level of PROTEINURIA). The most severe form is the end-stage renal disease (CHRONIC KIDNEY FAILURE). (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Cmax was not statistically different between the groups, while AUC and T1/2el increased, and CL/F decreased, with increasing severity of CKD." | 2.79 | Pharmacokinetic characterization of baclofen in patients with chronic kidney disease: dose adjustment recommendations. ( Barrière, O; Larouche, R; Perreault, MM; Pichette, V; Shink, E; Tanguay, M; Tremblay, PO; Vlavonou, R, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 4 (57.14) | 2.80 |
| Authors | Studies |
|---|---|
| Grech, E | 1 |
| Attard, SC | 1 |
| Attard, A | 1 |
| Farrugia, E | 1 |
| Muanda, FT | 1 |
| Blake, PG | 1 |
| Weir, MA | 1 |
| Bathini, L | 1 |
| Chauvin, K | 1 |
| Dixon, SN | 1 |
| McArthur, E | 1 |
| Sontrop, JM | 1 |
| Moist, L | 1 |
| Kim, RB | 1 |
| Garg, AX | 1 |
| Mitsuboshi, S | 1 |
| Pelter, M | 1 |
| Bagsic, SRS | 1 |
| Nicholson, L | 1 |
| Sriperumbuduri, S | 1 |
| Hiremath, S | 1 |
| Vlavonou, R | 1 |
| Perreault, MM | 1 |
| Barrière, O | 1 |
| Shink, E | 1 |
| Tremblay, PO | 1 |
| Larouche, R | 1 |
| Pichette, V | 1 |
| Tanguay, M | 1 |
| Niehaus, MT | 1 |
| Elliott, NC | 1 |
| Katz, KD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pharmacokinetic and Bioequivalence Comparison of Baclofen and Chlorzoxazone When Administered Individually or Concurrently[NCT05257447] | Phase 1 | 19 participants (Actual) | Interventional | 2022-04-27 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for baclofen and Renal Insufficiency, Chronic
| Article | Year |
|---|---|
The case for cautious consumption: NSAIDs in chronic kidney disease.
Topics: Acute Kidney Injury; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Baclofen; Cost-Ben | 2019 |
1 trial available for baclofen and Renal Insufficiency, Chronic
| Article | Year |
|---|---|
Pharmacokinetic characterization of baclofen in patients with chronic kidney disease: dose adjustment recommendations.
Topics: Adult; Aged; Aged, 80 and over; Baclofen; Creatinine; Female; GABA-B Receptor Agonists; Glomerular F | 2014 |
5 other studies available for baclofen and Renal Insufficiency, Chronic
| Article | Year |
|---|---|
Baclofen toxicity in a patient with advanced chronic kidney disease.
Topics: Baclofen; Chronic Disease; Humans; Kidney Failure, Chronic; Renal Insufficiency, Chronic | 2023 |
Association of Baclofen With Falls and Fractures in Patients With CKD.
Topics: Accidental Falls; Aged; Baclofen; Fractures, Bone; GABA-B Receptor Agonists; Global Health; Humans; | 2021 |
Association Between Baclofen and Respiratory Depression in Patients With Chronic Kidney Disease.
Topics: Age Factors; Aged; Baclofen; Body Weight; Female; Humans; Male; Middle Aged; Propiophenones; Renal I | 2021 |
Oral baclofen toxicity in older patients with chronic kidney disease.
Topics: Administration, Oral; Aged; Baclofen; Contraindications, Drug; Female; Humans; Male; Muscle Relaxant | 2021 |
Baclofen Toxicity Causing Acute, Reversible Dyskinesia.
Topics: Aged, 80 and over; Back Pain; Baclofen; Coronary Artery Disease; Diabetes Mellitus; Drug Interaction | 2016 |