baclofen has been researched along with Recrudescence in 33 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " A post hoc analysis stratifying according to whether there had been a comorbid anxiety disorder, revealed a beneficial effect of baclofen 30 mg/day versus placebo on time to lapse and relapse (P < 0." | 9.19 | Baclofen for the Treatment of Alcohol Dependence and Possible Role of Comorbid Anxiety. ( Addolorato, G; Baillie, A; Haber, PS; Leggio, L; Leung, S; Morley, KC, 2014) |
| " HDB induces frequent neuropsychiatric adverse events (AEs)." | 5.42 | Safety and drinking outcomes among patients with comorbid alcohol dependence and borderline personality disorder treated with high-dose baclofen: a comparative cohort study. ( Auffret, M; Bordet, R; Cottencin, O; Danel, T; Deheul, S; Gautier, S; Langlois, C; Rolland, B; Valin, T, 2015) |
| "Data from a randomised controlled trial (RCT) (N = 104), in which AUD patients received placebo or baclofen (30 mg/day or 75 mg/day) for 12 weeks, were analysed to determine predictive effects of the following four clinical characteristics: alcoholic liver disease (ALD), baseline alcohol consumption, craving and anxiety." | 5.30 | Clinical Predictors of Response to Baclofen in the Treatment of Alcohol use Disorder: Results from the BacALD Trial. ( Baillie, A; Haber, PS; Morley, KC; Rombouts, SA, 2019) |
| " A post hoc analysis stratifying according to whether there had been a comorbid anxiety disorder, revealed a beneficial effect of baclofen 30 mg/day versus placebo on time to lapse and relapse (P < 0." | 5.19 | Baclofen for the Treatment of Alcohol Dependence and Possible Role of Comorbid Anxiety. ( Addolorato, G; Baillie, A; Haber, PS; Leggio, L; Leung, S; Morley, KC, 2014) |
| "Intrathecal baclofen treatment (ITB) is widely used in children with cerebral palsy." | 3.79 | Dose-dependent relapse of hiatus hernia after administration of intrathecal baclofen treatment--a rare complication. ( Weber, P, 2013) |
| "Intrathecal Baclofen and Clonidine may be used as alternatives to provide spinally mediated antinociception when intraspinal opioid fails due to pharmacological side effects such as persistent edema." | 3.76 | Recurrent cellulitis associated with long-term intrathecal opioid infusion therapy: a case report and review of the literature. ( Chiravuri, S; Couch, JP; Liu, H; Ruan, X; Wang, F, 2010) |
| "Previous randomised placebo-controlled trials with low-to-medium doses of baclofen (30-60mg) showed inconsistent results, but case studies suggested a dose-response effect and positive outcomes in patients on high doses of baclofen (up to 270mg)." | 2.82 | Efficacy and safety of high-dose baclofen for the treatment of alcohol dependence: A multicentre, randomised, double-blind controlled trial. ( Bakker, A; Beraha, EM; Bodewits, P; de Jong, D; Defourny, H; Geest, DV; Goudriaan, AE; Salemink, E; Schiphof, T; Smits, N; van den Brink, W; van Tricht, M; Wiers, RW; Zwart, JW, 2016) |
| "Baclofen was associated with a significant reduction in state anxiety (F(1,73)= 5." | 2.75 | Efficacy and safety of baclofen for alcohol dependence: a randomized, double-blind, placebo-controlled trial. ( Flannery, BA; Gallop, R; Garbutt, JC; Kalka-Juhl, L; Kampov-Polevoy, AB, 2010) |
| "Participants had a diagnosis of alcohol dependence according the Diagnostic and Statistical Manual of Mental Disorders (DSM) IV or the International Classification of Diseases (ICD)-10 criteria who were currently drinking." | 2.58 | Baclofen for alcohol use disorder. ( Minozzi, S; Rösner, S; Saulle, R, 2018) |
| "R(+)-Baclofen was more effective than RS(±)-Baclofen in reducing ethanol intake and seeking during acute withdrawal and during relapse after abstinence." | 1.62 | Is R(+)-Baclofen the best option for the future of Baclofen in alcohol dependence pharmacotherapy? Insights from the preclinical side. ( Bloch, V; Echeverry-Alzate, V; Jeanblanc, J; Labat, L; Naassila, M; Sauton, P; Soichot, M; Vorspan, F, 2021) |
| "Baclofen has been shown to reduce alcohol consumption in alcohol-dependent individuals, but there is marked heterogeneity in response." | 1.48 | Moderation of baclofen response by a GABA ( Baillie, A; Dore, G; Fraser, I; Haber, PS; Luquin, N; Morley, KC; Phung, N; Trent, RJ, 2018) |
| " At a mean dosage of 40 mg/day (extremes: 30-210), the median daily alcohol consumption reduced from 80 to 0 g/day (P<0." | 1.46 | One year of baclofen in 100 patients with or without cirrhosis: a French real-life experience. ( Barrault, C; Béhar, V; Cadranel, JF; Costentin, C; Garioud, A; Hagège, H; Lison, H; Medmoun, M; Pulwermacher, G; Roudot-Thoraval, F, 2017) |
| "At present there is no satisfactory treatment against relapse of drug-seeking behavior." | 1.43 | Effects of baclofen and raclopride on reinstatement of cocaine self-administration in the rat. ( Castagné, V; Froger-Colléaux, C, 2016) |
| " HDB induces frequent neuropsychiatric adverse events (AEs)." | 1.42 | Safety and drinking outcomes among patients with comorbid alcohol dependence and borderline personality disorder treated with high-dose baclofen: a comparative cohort study. ( Auffret, M; Bordet, R; Cottencin, O; Danel, T; Deheul, S; Gautier, S; Langlois, C; Rolland, B; Valin, T, 2015) |
| " Meropenem serum concentrations were obtained and indicated that T>MIC was at least 75% of the dosing interval." | 1.42 | Success With Extended-Infusion Meropenem After Recurrence of Baclofen Pump-Related Achromobacter Xylosoxidans Meningitis in an Adolescent. ( Christenson, JC; Jackson, NG; Knoderer, CA; Manaloor, JJ; Nichols, KR, 2015) |
| "Baclofen was first used in the treatment of trigeminal neuralgia in 1980 and is currently used in the management of various types of neuropathic pain." | 1.30 | Baclofen for prevention of migraine. ( Hering-Hanit, R, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (6.06) | 18.2507 |
| 2000's | 8 (24.24) | 29.6817 |
| 2010's | 20 (60.61) | 24.3611 |
| 2020's | 3 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Reiner, DJ | 1 |
| Lofaro, OM | 1 |
| Applebey, SV | 1 |
| Korah, H | 1 |
| Venniro, M | 1 |
| Cifani, C | 1 |
| Bossert, JM | 3 |
| Shaham, Y | 2 |
| Echeverry-Alzate, V | 1 |
| Jeanblanc, J | 1 |
| Sauton, P | 1 |
| Bloch, V | 1 |
| Labat, L | 1 |
| Soichot, M | 1 |
| Vorspan, F | 1 |
| Naassila, M | 1 |
| Augier, E | 1 |
| Barrault, C | 1 |
| Lison, H | 1 |
| Roudot-Thoraval, F | 1 |
| Garioud, A | 1 |
| Costentin, C | 1 |
| Béhar, V | 1 |
| Medmoun, M | 1 |
| Pulwermacher, G | 1 |
| Hagège, H | 1 |
| Cadranel, JF | 1 |
| Devine, OP | 1 |
| Harborne, AC | 1 |
| Lo, WB | 1 |
| Price, R | 1 |
| Pelloux, Y | 1 |
| Minier-Toribio, A | 1 |
| Hoots, JK | 1 |
| Bianchi, PC | 1 |
| Carneiro de Oliveira, PE | 1 |
| Palombo, P | 1 |
| Leão, RM | 1 |
| Cogo-Moreira, H | 1 |
| Planeta, CDS | 1 |
| Cruz, FC | 1 |
| Morley, KC | 3 |
| Luquin, N | 1 |
| Baillie, A | 3 |
| Fraser, I | 1 |
| Trent, RJ | 1 |
| Dore, G | 1 |
| Phung, N | 1 |
| Haber, PS | 3 |
| Minozzi, S | 1 |
| Saulle, R | 1 |
| Rösner, S | 1 |
| Rombouts, SA | 1 |
| Weber, P | 1 |
| Leung, S | 1 |
| Addolorato, G | 1 |
| Leggio, L | 1 |
| Rolland, B | 1 |
| Valin, T | 1 |
| Langlois, C | 1 |
| Auffret, M | 1 |
| Gautier, S | 1 |
| Deheul, S | 1 |
| Danel, T | 1 |
| Bordet, R | 1 |
| Cottencin, O | 1 |
| Kamal, RM | 1 |
| Schellekens, A | 1 |
| De Jong, CA | 1 |
| Dijkstra, BA | 1 |
| Davanzo, JR | 1 |
| Rizk, E | 1 |
| Nichols, KR | 1 |
| Knoderer, CA | 1 |
| Jackson, NG | 1 |
| Manaloor, JJ | 1 |
| Christenson, JC | 1 |
| Froger-Colléaux, C | 1 |
| Castagné, V | 1 |
| Beraha, EM | 1 |
| Salemink, E | 1 |
| Goudriaan, AE | 1 |
| Bakker, A | 1 |
| de Jong, D | 1 |
| Smits, N | 1 |
| Zwart, JW | 1 |
| Geest, DV | 1 |
| Bodewits, P | 1 |
| Schiphof, T | 1 |
| Defourny, H | 1 |
| van Tricht, M | 1 |
| van den Brink, W | 1 |
| Wiers, RW | 1 |
| Karneev, AN | 1 |
| Solov'eva, EIu | 1 |
| Fedin, AI | 1 |
| Peerdeman, SM | 1 |
| de Groot, V | 1 |
| Feller, RE | 1 |
| Lasseter, HC | 1 |
| Ramirez, DR | 1 |
| Xie, X | 1 |
| Fuchs, RA | 2 |
| Ruan, X | 1 |
| Liu, H | 1 |
| Couch, JP | 1 |
| Wang, F | 1 |
| Chiravuri, S | 1 |
| Garbutt, JC | 1 |
| Kampov-Polevoy, AB | 1 |
| Gallop, R | 1 |
| Kalka-Juhl, L | 1 |
| Flannery, BA | 1 |
| Bell, J | 1 |
| Collins, R | 1 |
| Stern, AL | 1 |
| Rourke, KF | 1 |
| Fischler, AH | 1 |
| Jordan, GH | 1 |
| Evans, KA | 1 |
| Parker, MP | 1 |
| See, RE | 1 |
| Han, Y | 1 |
| Qin, J | 1 |
| Bu, DF | 1 |
| Chang, XZ | 1 |
| Yang, ZX | 1 |
| Du, JB | 1 |
| Grande, LA | 1 |
| Loeser, JD | 1 |
| Samii, A | 1 |
| Maccioni, P | 1 |
| Bienkowski, P | 1 |
| Carai, MA | 1 |
| Gessa, GL | 1 |
| Colombo, G | 1 |
| Boshes, RA | 1 |
| Afonso, JA | 1 |
| Tanev, K | 1 |
| Hering-Hanit, R | 1 |
| Dickerman, RD | 1 |
| Schneider, SJ | 1 |
2 reviews available for baclofen and Recrudescence
| Article | Year |
|---|---|
Recent Advances in the Potential of Positive Allosteric Modulators of the GABAB Receptor to Treat Alcohol Use Disorder.
Topics: Acetamides; Alcoholism; Animals; Baclofen; Bacterial Proteins; GABA-B Receptor Agonists; Mice; Rats; | 2021 |
Baclofen for alcohol use disorder.
Topics: Acamprosate; Alcohol Deterrents; Alcohol Drinking; Alcoholism; Baclofen; Craving; Depression; Female | 2018 |
5 trials available for baclofen and Recrudescence
| Article | Year |
|---|---|
Clinical Predictors of Response to Baclofen in the Treatment of Alcohol use Disorder: Results from the BacALD Trial.
Topics: Adolescent; Adult; Aged; Alcohol Drinking; Alcoholism; Anxiety; Baclofen; Craving; Dose-Response Rel | 2019 |
Baclofen for the Treatment of Alcohol Dependence and Possible Role of Comorbid Anxiety.
Topics: Adult; Alcohol Abstinence; Alcoholism; Anxiety; Baclofen; Double-Blind Method; Female; GABA-B Recept | 2014 |
Baclofen as relapse prevention in the treatment of Gamma- Hydroxybutyrate (GHB) dependence: an open label study.
Topics: Adult; Baclofen; Clinical Protocols; Craving; Female; GABA Agonists; Humans; Male; Quality of Life; | 2015 |
Efficacy and safety of high-dose baclofen for the treatment of alcohol dependence: A multicentre, randomised, double-blind controlled trial.
Topics: Adolescent; Adult; Aged; Alcoholism; Baclofen; Dose-Response Relationship, Drug; Double-Blind Method | 2016 |
Efficacy and safety of baclofen for alcohol dependence: a randomized, double-blind, placebo-controlled trial.
Topics: Adolescent; Adult; Alcohol Drinking; Alcoholism; Anxiety; Baclofen; Depression; Double-Blind Method; | 2010 |
26 other studies available for baclofen and Recrudescence
| Article | Year |
|---|---|
Role of Projections between Piriform Cortex and Orbitofrontal Cortex in Relapse to Fentanyl Seeking after Palatable Food Choice-Induced Voluntary Abstinence.
Topics: Analgesics, Opioid; Animals; Baclofen; Choice Behavior; Drug-Seeking Behavior; Female; Fentanyl; Foo | 2020 |
Is R(+)-Baclofen the best option for the future of Baclofen in alcohol dependence pharmacotherapy? Insights from the preclinical side.
Topics: Alcohol Drinking; Alcoholism; Animals; Baclofen; Dose-Response Relationship, Drug; GABA-B Receptor A | 2021 |
One year of baclofen in 100 patients with or without cirrhosis: a French real-life experience.
Topics: Adult; Alcohol Abstinence; Alcohol Drinking; Alcoholism; Baclofen; Female; France; GABA-B Receptor A | 2017 |
Colonic perforation by an intrathecal baclofen pump catheter causing delayed
Topics: Anti-Bacterial Agents; Baclofen; Catheterization; Catheters, Indwelling; Device Removal; Disabled Pe | 2017 |
Opposite Effects of Basolateral Amygdala Inactivation on Context-Induced Relapse to Cocaine Seeking after Extinction versus Punishment.
Topics: Amygdala; Animals; Baclofen; Cocaine-Related Disorders; Conditioning, Operant; Extinction, Psycholog | 2018 |
Functional inactivation of the orbitofrontal cortex disrupts context-induced reinstatement of alcohol seeking in rats.
Topics: Alcohol Drinking; Alcoholism; Animals; Baclofen; Conditioning, Operant; Drug-Seeking Behavior; Femal | 2018 |
Moderation of baclofen response by a GABA
Topics: Adult; Alcohol Drinking; Alcoholism; Baclofen; Female; GABA-B Receptor Agonists; Humans; Male; Middl | 2018 |
Dose-dependent relapse of hiatus hernia after administration of intrathecal baclofen treatment--a rare complication.
Topics: Adolescent; Baclofen; Cerebral Palsy; Dose-Response Relationship, Drug; Hernia, Hiatal; Humans; Infu | 2013 |
Safety and drinking outcomes among patients with comorbid alcohol dependence and borderline personality disorder treated with high-dose baclofen: a comparative cohort study.
Topics: Adult; Alcohol Abstinence; Alcohol Drinking; Alcoholism; Baclofen; Borderline Personality Disorder; | 2015 |
Baclofen overdose from possible intrinsic malfunction of SynchroMed II pump.
Topics: Baclofen; Cerebral Palsy; Child; Device Removal; Drug Overdose; Equipment Failure; GABA-B Receptor A | 2015 |
Success With Extended-Infusion Meropenem After Recurrence of Baclofen Pump-Related Achromobacter Xylosoxidans Meningitis in an Adolescent.
Topics: Achromobacter denitrificans; Adolescent; Anti-Bacterial Agents; Baclofen; Drug Administration Schedu | 2015 |
Effects of baclofen and raclopride on reinstatement of cocaine self-administration in the rat.
Topics: Animals; Baclofen; Behavior, Animal; Cocaine; Dopamine D2 Receptor Antagonists; Drug-Seeking Behavio | 2016 |
[Efficacy and tolerability of the combined therapy with mesipol and baclosan in chronic recurrent vertebrogenic pain syndrome].
Topics: Back Pain; Baclofen; Cyclooxygenase Inhibitors; Female; Humans; Injections, Intramuscular; Male; Mel | 2008 |
In situ treatment of an infected intrathecal baclofen pump implant with gentamicin-impregnated collagen fleece.
Topics: Anti-Bacterial Agents; Baclofen; Collagen; Debridement; Drug Implants; Gentamicins; Humans; Infusion | 2010 |
Involvement of the lateral orbitofrontal cortex in drug context-induced reinstatement of cocaine-seeking behavior in rats.
Topics: Animals; Baclofen; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine Uptake Inhib | 2009 |
Recurrent cellulitis associated with long-term intrathecal opioid infusion therapy: a case report and review of the literature.
Topics: Analgesics, Opioid; Baclofen; Cellulitis; Clonidine; Edema; Female; GABA Agonists; Humans; Hydromorp | 2010 |
Gamma-butyrolactone (GBL) dependence and withdrawal.
Topics: 4-Butyrolactone; Adult; Ambulatory Care; Baclofen; Delirium; Diazepam; Dose-Response Relationship, D | 2011 |
Role of ventral subiculum in context-induced reinstatement of heroin seeking in rats.
Topics: Animals; Baclofen; Cues; Drug-Seeking Behavior; Extinction, Psychological; GABA-A Receptor Agonists; | 2014 |
Treatment of recurrent idiopathic priapism with oral baclofen.
Topics: Administration, Oral; Adult; Baclofen; GABA Agonists; Humans; Male; Priapism; Recurrence | 2002 |
Differential involvement of orbitofrontal cortex subregions in conditioned cue-induced and cocaine-primed reinstatement of cocaine seeking in rats.
Topics: Animals; Baclofen; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological | 2004 |
[Gamma-aminobutyric acid B receptor regulates the expression of hydrogen sulfide/cystathionine-beta-synthase system in recurrent febrile seizures].
Topics: Animals; Baclofen; Cystathionine beta-Synthase; Hydrogen Sulfide; Rats; Rats, Sprague-Dawley; Recept | 2006 |
Recurrent transient global amnesia with intrathecal baclofen.
Topics: Amnesia, Anterograde; Baclofen; Female; Humans; Hypotension; Injections, Spinal; Isosorbide Dinitrat | 2008 |
Baclofen attenuates cue-induced reinstatement of alcohol-seeking behavior in Sardinian alcohol-preferring (sP) rats.
Topics: Alcohol Drinking; Animals; Baclofen; Behavior, Animal; Choice Behavior; Cues; Extinction, Psychologi | 2008 |
Treatment of Meige's syndrome with ECT.
Topics: Anxiety Disorders; Baclofen; Clonazepam; Combined Modality Therapy; Comorbidity; Depressive Disorder | 1999 |
Baclofen for prevention of migraine.
Topics: Adult; Baclofen; Dose-Response Relationship, Drug; Female; GABA Agonists; Humans; Male; Middle Aged; | 1999 |
Recurrent intrathecal baclofen pump catheter leakage: A surgical observation with recommendations.
Topics: Baclofen; Catheterization; Cerebral Palsy; Child, Preschool; Equipment Failure; Equipment Failure An | 2002 |