Page last updated: 2024-10-23

baclofen and Pyrexia

baclofen has been researched along with Pyrexia in 23 studies

Research Excerpts

ExcerptRelevanceReference
"Baclofen withdrawal syndrome is a rare and potentially life-threatening condition manifesting with autonomic dysreflexia, high fevers, spasticity, seizures, and multiorgan failure."7.76Reversible electrocardiogram changes and cardiomyopathy secondary to baclofen withdrawal syndrome. ( Kireyev, D; Poh, KK, 2010)
"A 29-year-old man with C6 tetraplegia (ASIA A) using an implanted baclofen pump and intrathecal catheter infusion system for spasticity control developed severe spasticity, hyperthermia, hypotension, rhabdomyolysis, and disseminated intravascular coagulation after catheter disconnection."7.70Hyperthermia, rhabdomyolysis, and disseminated intravascular coagulation associated with baclofen pump catheter failure. ( Christopherson, MW; Reeves, RK; Stolp-Smith, KA, 1998)
" The patient continued to have fever and autonomic instability without evidence of infection which entirely resolved within 24 hours of reinstitution of full preadmission dosing of oral baclofen."5.33Baclofen withdrawal: a cause of prolonged fever in the intensive care unit. ( Cunningham, JA; Jelic, S, 2005)
"Baclofen (Lioresal) is a drug of choice to treat spasticity and is increasingly being administered intrathecally via an implantable pump in cases refractory to oral therapy."5.32Intrathecal baclofen withdrawal mimicking sepsis. ( Amin, Y; Kao, LW; Kirk, MA; Turner, MS, 2003)
" He developed acute kidney injury at hospital secondary to vancomycin use, and mental status declined."5.05Encephalopathy of Unknown Origin in a Baclofen Patient: Case Report and Review of the Literature. ( Abraham, M; Behmer Hansen, R; Gold, J; Lad, M; Mammis, A; Zhao, K, 2020)
" Syndromes include adrenergic "fever," anticholinergic "fever," antidopaminergic "fever," serotonin syndrome, malignant hyperthermia, uncoupling of oxidative phosphorylation, and withdrawal from baclofen."4.86Adverse drug reactions resulting in hyperthermia in the intensive care unit. ( McAllen, KJ; Schwartz, DR, 2010)
"We report a case of a 53-year-old woman who presented initially with sepsis and later in her stay developed a severe and rapidly progressing hyperthermia after a decrease in oral baclofen dosage."3.96Severe hyperthermia due to oral baclofen withdrawal. ( Kim, E; Nadherny, W; Paul, V; Righter, K, 2020)
"Baclofen withdrawal syndrome is a rare and potentially life-threatening condition manifesting with autonomic dysreflexia, high fevers, spasticity, seizures, and multiorgan failure."3.76Reversible electrocardiogram changes and cardiomyopathy secondary to baclofen withdrawal syndrome. ( Kireyev, D; Poh, KK, 2010)
"A 29-year-old man with C6 tetraplegia (ASIA A) using an implanted baclofen pump and intrathecal catheter infusion system for spasticity control developed severe spasticity, hyperthermia, hypotension, rhabdomyolysis, and disseminated intravascular coagulation after catheter disconnection."3.70Hyperthermia, rhabdomyolysis, and disseminated intravascular coagulation associated with baclofen pump catheter failure. ( Christopherson, MW; Reeves, RK; Stolp-Smith, KA, 1998)
"Rapid baclofen withdrawal is known to cause markedly increased spasticity, but high fever associated with this complication has not been reported."3.68Hyperthermia associated with baclofen withdrawal and increased spasticity. ( Hurvitz, EA; Mandac, BR; Nelson, VS, 1993)
"Hiccups are involuntary diaphragmatic muscle contractions with early glottis closure terminating inspiration."1.62Persistent hiccup: A rare presentation of COVID-19. ( Bakheet, N; El-Shazly, M; Fouad, R; Hussin, W; Kassem, AM, 2021)
" The patient continued to have fever and autonomic instability without evidence of infection which entirely resolved within 24 hours of reinstitution of full preadmission dosing of oral baclofen."1.33Baclofen withdrawal: a cause of prolonged fever in the intensive care unit. ( Cunningham, JA; Jelic, S, 2005)
"Baclofen (Lioresal) is a drug of choice to treat spasticity and is increasingly being administered intrathecally via an implantable pump in cases refractory to oral therapy."1.32Intrathecal baclofen withdrawal mimicking sepsis. ( Amin, Y; Kao, LW; Kirk, MA; Turner, MS, 2003)
" Overall, the data obtained here suggest that positive modulation of GABAB receptors may serve as a novel therapeutic strategy for the development of anxiolytics, with a superior side effect profile to both baclofen and benzodiazepines."1.32Behavioral characterization of the novel GABAB receptor-positive modulator GS39783 (N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine): anxiolytic-like activity without side effects associated with baclofen or benzodiazepines. ( Bettler, B; Chaperon, F; Cryan, JF; Froestl, W; Gentsch, C; Kaupmann, K; Kelly, PH; Lingenhoehl, K; Mombereau, C; Spooren, WP, 2004)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.35)18.7374
1990's5 (21.74)18.2507
2000's8 (34.78)29.6817
2010's6 (26.09)24.3611
2020's3 (13.04)2.80

Authors

AuthorsStudies
Gold, J1
Zhao, K1
Abraham, M1
Behmer Hansen, R1
Lad, M1
Mammis, A1
Paul, V1
Righter, K1
Kim, E1
Nadherny, W1
Bakheet, N1
Fouad, R1
Kassem, AM1
Hussin, W1
El-Shazly, M1
Sengupta, D1
Kapoor, I1
Mahajan, C1
Prabhakar, H1
Sweeney, FF1
O'Leary, OF1
Cryan, JF3
Li, X1
Kaczanowska, K1
Finn, MG1
Markou, A1
Risbrough, VB1
Huang, YS1
Hsiao, MC1
Lee, M1
Huang, YC1
Lee, JD1
McAllen, KJ1
Schwartz, DR1
Kireyev, D1
Poh, KK1
Wang, YY1
Qin, J1
Han, Y1
Cai, J1
Xing, GG1
Alden, TD1
Lytle, RA1
Park, TS1
Noetzel, MJ1
Ojemann, JG1
Meythaler, JM1
Roper, JF1
Brunner, RC1
Kao, LW1
Amin, Y1
Kirk, MA1
Turner, MS1
Kelly, PH1
Chaperon, F1
Gentsch, C1
Mombereau, C1
Lingenhoehl, K1
Froestl, W1
Bettler, B1
Kaupmann, K1
Spooren, WP1
Cunningham, JA1
Jelic, S1
Jacobson, LH1
Pirovino, M1
Meier, J1
Meyer, M1
Waldmeier, P1
Schmid, M1
Khorasani, A1
Peruzzi, WT1
Mandac, BR1
Hurvitz, EA1
Nelson, VS2
Grenier, B1
Mesli, A1
Cales, J1
Castel, JP1
Maurette, P1
Reeves, RK1
Stolp-Smith, KA1
Christopherson, MW1
Green, LB1
Wu, SS1
Dolan, KA1
Michael Ferrante, F1

Reviews

4 reviews available for baclofen and Pyrexia

ArticleYear
Encephalopathy of Unknown Origin in a Baclofen Patient: Case Report and Review of the Literature.
    World neurosurgery, 2020, Volume: 136

    Topics: Acute Kidney Injury; Adult; Anti-Bacterial Agents; Baclofen; Brain Diseases; Electroencephalography;

2020
Adverse drug reactions resulting in hyperthermia in the intensive care unit.
    Critical care medicine, 2010, Volume: 38, Issue:6 Suppl

    Topics: Baclofen; Critical Care; Drug-Related Side Effects and Adverse Reactions; Fever; Humans; Intensive C

2010
Intrathecal baclofen withdrawal: a case report and review of the literature.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2002, Volume: 18, Issue:9-10

    Topics: Adolescent; Adrenoleukodystrophy; Baclofen; Equipment Failure; Fever; Humans; Infusion Pumps, Implan

2002
Death after acute withdrawal of intrathecal baclofen: case report and literature review.
    Archives of physical medicine and rehabilitation, 1999, Volume: 80, Issue:12

    Topics: Administration, Oral; Adult; Baclofen; Brain Death; Cervical Vertebrae; Equipment Failure; Fatal Out

1999

Other Studies

19 other studies available for baclofen and Pyrexia

ArticleYear
Severe hyperthermia due to oral baclofen withdrawal.
    BMJ case reports, 2020, Sep-29, Volume: 13, Issue:9

    Topics: Administration, Oral; Baclofen; Dose-Response Relationship, Drug; Female; Fever; Humans; Middle Aged

2020
Persistent hiccup: A rare presentation of COVID-19.
    Respiratory investigation, 2021, Volume: 59, Issue:2

    Topics: Baclofen; Biomarkers; COVID-19; COVID-19 Testing; Fever; Hiccup; Humans; Hydroxychloroquine; Male; M

2021
Baclofen for neurogenic fever in a patient with cerebral contusion.
    Journal of clinical anesthesia, 2019, Volume: 55

    Topics: Adult; Baclofen; Brain Contusion; Fever; GABA-B Receptor Agonists; Humans; Male; Treatment Outcome;

2019
Activation but not blockade of GABAB receptors during early-life alters anxiety in adulthood in BALB/c mice.
    Neuropharmacology, 2014, Volume: 81

    Topics: Analysis of Variance; Animals; Animals, Newborn; Anxiety; Baclofen; Benzylamines; Defense Mechanisms

2014
The GABA(B) receptor positive modulator BHF177 attenuated anxiety, but not conditioned fear, in rats.
    Neuropharmacology, 2015, Volume: 97

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Baclofen; Buspirone; Conditioning, Classical; Dose-Response R

2015
Baclofen successfully abolished prolonged central hyperthermia in a patient with basilar artery occlusion.
    Acta neurologica Taiwanica, 2009, Volume: 18, Issue:2

    Topics: Aged; Baclofen; Body Temperature Regulation; Brain Stem; Female; Fever; Humans; Stroke; Vertebrobasi

2009
Reversible electrocardiogram changes and cardiomyopathy secondary to baclofen withdrawal syndrome.
    The American heart hospital journal, 2010,Summer, Volume: 8, Issue:1

    Topics: Adult; Autonomic Dysreflexia; Baclofen; Bundle-Branch Block; Electrocardiography; Fever; GABA-B Rece

2010
Hyperthermia induces epileptiform discharges in cultured rat cortical neurons.
    Brain research, 2011, Oct-12, Volume: 1417

    Topics: Action Potentials; Animals; Baclofen; Cells, Cultured; Cerebral Cortex; Fever; Fluorescent Antibody

2011
Cyproheptadine for intrathecal baclofen withdrawal.
    Archives of physical medicine and rehabilitation, 2003, Volume: 84, Issue:5

    Topics: Acute Disease; Adult; Baclofen; Cerebral Palsy; Cyproheptadine; Diagnosis, Differential; Female; Fev

2003
Intrathecal baclofen withdrawal mimicking sepsis.
    The Journal of emergency medicine, 2003, Volume: 24, Issue:4

    Topics: Baclofen; Child, Preschool; Clinical Protocols; Decerebrate State; Diagnosis, Differential; Emergenc

2003
Behavioral characterization of the novel GABAB receptor-positive modulator GS39783 (N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine): anxiolytic-like activity without side effects associated with baclofen or benzodiazepines.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 310, Issue:3

    Topics: Animals; Anti-Anxiety Agents; Avoidance Learning; Baclofen; Benzodiazepines; Body Temperature; Cyclo

2004
Baclofen withdrawal: a cause of prolonged fever in the intensive care unit.
    Anaesthesia and intensive care, 2005, Volume: 33, Issue:4

    Topics: Adult; Baclofen; Diagnosis, Differential; Dose-Response Relationship, Drug; Female; Fever; Humans; I

2005
Evaluation of the anxiolytic-like profile of the GABAB receptor positive modulator CGP7930 in rodents.
    Neuropharmacology, 2008, Volume: 54, Issue:5

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Baclofen; Behavior, Animal; Benzodiazepines; Body Temperature

2008
[Malignant neuroleptics syndrome].
    Deutsche medizinische Wochenschrift (1946), 1984, Mar-09, Volume: 109, Issue:10

    Topics: Adult; Amantadine; Baclofen; Cerebrospinal Fluid; Chromatography, Liquid; Cognition Disorders; Femal

1984
Dantrolene treatment for abrupt intrathecal baclofen withdrawal.
    Anesthesia and analgesia, 1995, Volume: 80, Issue:5

    Topics: Adult; Baclofen; Dantrolene; Fever; Humans; Male; Muscle Spasticity; Spinal Cord Injuries; Substance

1995
Hyperthermia associated with baclofen withdrawal and increased spasticity.
    Archives of physical medicine and rehabilitation, 1993, Volume: 74, Issue:1

    Topics: Adolescent; Baclofen; Fever; Humans; Male; Muscle Spasticity; Quadriplegia; Substance Withdrawal Syn

1993
[Severe hyperthermia caused by sudden withdrawal of continuous intrathecal administration of baclofen].
    Annales francaises d'anesthesie et de reanimation, 1996, Volume: 15, Issue:5

    Topics: Adult; Baclofen; Fever; Humans; Infusion Pumps, Implantable; Injections, Spinal; Male; Muscle Hypoto

1996
Hyperthermia, rhabdomyolysis, and disseminated intravascular coagulation associated with baclofen pump catheter failure.
    Archives of physical medicine and rehabilitation, 1998, Volume: 79, Issue:3

    Topics: Adult; Baclofen; Catheters, Indwelling; Dantrolene; Disseminated Intravascular Coagulation; Equipmen

1998
Febrile reaction to subarachnoid baclofen administration.
    Anesthesiology, 2002, Volume: 96, Issue:5

    Topics: Adult; Baclofen; Drug Delivery Systems; Drug Implants; Female; Fever; GABA Agonists; Humans; Injecti

2002